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Volumn 19, Issue 6 B, 1999, Pages 5423-5428

Synergistic effect of gemcitabine and irinotecan (CPT-11) on breast and small cell lung cancer cell lines

Author keywords

Breast cancer; CPT 11; Gemcitabine; Irinotecan; Small cell lung cancer

Indexed keywords

GEMCITABINE; IRINOTECAN;

EID: 0033368083     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (45)

References (33)
  • 3
    • 0028033227 scopus 로고
    • Single agent activity of weekly gemcitabine in advanced non-small-cell lung cancer: A phase II study
    • Anderson H, Lund B, Bach F, Thatcher N, Walling J and Hansen HH: Single agent activity of weekly gemcitabine in advanced non-small-cell lung cancer: a phase II study. J Clin Oncol 12: 1821-1826, 1994.
    • (1994) J Clin Oncol , vol.12 , pp. 1821-1826
    • Anderson, H.1    Lund, B.2    Bach, F.3    Thatcher, N.4    Walling, J.5    Hansen, H.H.6
  • 4
    • 0028297564 scopus 로고
    • Gemcitabine is an active new agent in previously untreated extensive small cell lung cancer (SCLC): A study of National Cancer Institute of Canada Clinical Trials Group
    • Cormier Y, Eisenhauer E, Muldal A, Gregg R, Ayoub J, Goss G, Stewart D, Tarasoff P and Wong D: Gemcitabine is an active new agent in previously untreated extensive small cell lung cancer (SCLC): a study of National Cancer Institute of Canada Clinical Trials Group. Ann Oncol 5: 283-285, 1994.
    • (1994) Ann Oncol , vol.5 , pp. 283-285
    • Cormier, Y.1    Eisenhauer, E.2    Muldal, A.3    Gregg, R.4    Ayoub, J.5    Goss, G.6    Stewart, D.7    Tarasoff, P.8    Wong, D.9
  • 6
    • 0029782426 scopus 로고    scopus 로고
    • Excision of 2′,2′-difluorodeoxycytidine (gemcitabine) monophosphate residues from DNA
    • Gandhi V, Legha J, Chen F, Hertel LW and Plunkett W: Excision of 2′,2′-difluorodeoxycytidine (gemcitabine) monophosphate residues from DNA. Cancer Res 56: 4453-4459, 1996.
    • (1996) Cancer Res , vol.56 , pp. 4453-4459
    • Gandhi, V.1    Legha, J.2    Chen, F.3    Hertel, L.W.4    Plunkett, W.5
  • 7
    • 0028832342 scopus 로고
    • Gemcitabine: A modulator of intracellular nucleotide and deoxynucleotide metabolism
    • Heinemann V, Schulz L, Issels RD and Plunkett W: Gemcitabine: a modulator of intracellular nucleotide and deoxynucleotide metabolism. Semin Oncol 22 (4 Suppl 11): 11-18, 1995.
    • (1995) Semin Oncol , vol.22 , Issue.4 SUPPL. 11 , pp. 11-18
    • Heinemann, V.1    Schulz, L.2    Issels, R.D.3    Plunkett, W.4
  • 8
    • 0023552964 scopus 로고
    • Antitumor activity of 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxy-camptothecin, a novel water-soluble derivative of camptothecin, against murine tumors
    • Kunimoto T, Nitta K, Tanaka T, Uehara N, Baba H, Takeuchi M, Yokokura T, Sawada S, Miyasaka T and Mutai M: Antitumor activity of 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxy-camptothecin, a novel water-soluble derivative of camptothecin, against murine tumors. Cancer Res 47: 5944-5947, 1987.
    • (1987) Cancer Res , vol.47 , pp. 5944-5947
    • Kunimoto, T.1    Nitta, K.2    Tanaka, T.3    Uehara, N.4    Baba, H.5    Takeuchi, M.6    Yokokura, T.7    Sawada, S.8    Miyasaka, T.9    Mutai, M.10
  • 9
    • 0025996996 scopus 로고
    • Intracellular roles of SN-38, a metabolite of the camptothecin derivative CPT-11, in the antitumor effect of CPT-11
    • Kawato Y, Aonuma M, Hirota Y, Kuga H and Sato K: Intracellular roles of SN-38, a metabolite of the camptothecin derivative CPT-11, in the antitumor effect of CPT-11. Cancer Res 51: 4187-4191, 1991.
    • (1991) Cancer Res , vol.51 , pp. 4187-4191
    • Kawato, Y.1    Aonuma, M.2    Hirota, Y.3    Kuga, H.4    Sato, K.5
  • 10
    • 0028221421 scopus 로고
    • Activity of CPT-11 (irinotecan hydrochloride), a topoisomerase I inhibitor, against human tumor colony-forming units
    • Shimada Y, Rothenberg ML, Hilsenbeck SG, Burris HA III, Degen D and Von Hoff DD: Activity of CPT-11 (irinotecan hydrochloride), a topoisomerase I inhibitor, against human tumor colony-forming units. Anticancer Drugs 5: 202-206, 1994.
    • (1994) Anticancer Drugs , vol.5 , pp. 202-206
    • Shimada, Y.1    Rothenberg, M.L.2    Hilsenbeck, S.G.3    Burris III, H.A.4    Degen, D.5    Von Hoff, D.D.6
  • 11
    • 0025785082 scopus 로고
    • Antitumor activity of a camptothecin derivative, CPT-11, against humor tumor xenografts in nude mice
    • Kawato Y, Furuta T, Aonuma M, Yasuoka T and Matsumoto K: Antitumor activity of a camptothecin derivative, CPT-11, against humor tumor xenografts in nude mice. Cancer Chemother Pharmacol 28: 192-198, 1991.
    • (1991) Cancer Chemother Pharmacol , vol.28 , pp. 192-198
    • Kawato, Y.1    Furuta, T.2    Aonuma, M.3    Yasuoka, T.4    Matsumoto, K.5
  • 12
    • 0023864510 scopus 로고
    • Antitumor effect of CPT-11, a new derivative of camptothecin, against pleiotropic drug-resistant tumors in vitro and in vivo
    • Tsuruo T, Matsuzaki T, Matsushita M, Saito H and Yokokura T: Antitumor effect of CPT-11, a new derivative of camptothecin, against pleiotropic drug-resistant tumors in vitro and in vivo. Cancer Chemother Pharmacol 21: 71-74, 1988.
    • (1988) Cancer Chemother Pharmacol , vol.21 , pp. 71-74
    • Tsuruo, T.1    Matsuzaki, T.2    Matsushita, M.3    Saito, H.4    Yokokura, T.5
  • 13
    • 0027194943 scopus 로고
    • Phase II study of CPT-11, a new camptothecin derivative, in metastatic colorectal cancer
    • CPT-11 Gastrointestinal Cancer Study Group
    • Shimada Y, Yoshino M, Wakui A, Nakao I, Sakata Y, Kambe M, Taguchi T and Ogawa N: Phase II study of CPT-11, a new camptothecin derivative, in metastatic colorectal cancer. CPT-11 Gastrointestinal Cancer Study Group. J Clin Oncol 11: 909-913, 1993.
    • (1993) J Clin Oncol , vol.11 , pp. 909-913
    • Shimada, Y.1    Yoshino, M.2    Wakui, A.3    Nakao, I.4    Sakata, Y.5    Kambe, M.6    Taguchi, T.7    Ogawa, N.8
  • 17
    • 0032168956 scopus 로고    scopus 로고
    • A phase II trial of CPT-11 in recurrent squamous carcinoma of the cervix: A gynecologic oncology study group
    • Look KY, Blessing JA, Levenback C, Kohler M, Chafe W and Roman LD: A phase II trial of CPT-11 in recurrent squamous carcinoma of the cervix: a gynecologic oncology study group. Gynecol Oncol 70: 334-338, 1998.
    • (1998) Gynecol Oncol , vol.70 , pp. 334-338
    • Look, K.Y.1    Blessing, J.A.2    Levenback, C.3    Kohler, M.4    Chafe, W.5    Roman, L.D.6
  • 19
    • 0026572562 scopus 로고
    • Megestrol acetate reverses multidrug resistance and interacts with P-glycoprotein
    • Fleming GF, Amato JM, Agresti M and Safa AR: Megestrol acetate reverses multidrug resistance and interacts with P-glycoprotein. Cancer Chemother Pharmacol 29: 445-459, 1992.
    • (1992) Cancer Chemother Pharmacol , vol.29 , pp. 445-459
    • Fleming, G.F.1    Amato, J.M.2    Agresti, M.3    Safa, A.R.4
  • 20
    • 0024847290 scopus 로고
    • What is synergy?
    • Berenbaum MC: What is synergy? Pharmacol Rev 41: 93-141, 1990.
    • (1990) Pharmacol Rev , vol.41 , pp. 93-141
    • Berenbaum, M.C.1
  • 21
    • 0021118703 scopus 로고
    • Quantitative analysis of dose-effect relationships: The combined effects of multiple drugs or enzyme inhibitors
    • Chou T-C and Talalay P: Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. Adv Enzyme Regul 22: 27-55, 1984.
    • (1984) Adv Enzyme Regul , vol.22 , pp. 27-55
    • Chou, T.-C.1    Talalay, P.2
  • 22
    • 0027993707 scopus 로고
    • Efficacy and safety profile of gemcitabine in non-small-cell lung cancer: A phase II study
    • Abratt RP, Bezwoda WR, Falkson G, Goedhals L, Hacking D and Rugg TA: Efficacy and safety profile of gemcitabine in non-small-cell lung cancer: a phase II study. J Clin Oncol 12: 1535-1540, 1994.
    • (1994) J Clin Oncol , vol.12 , pp. 1535-1540
    • Abratt, R.P.1    Bezwoda, W.R.2    Falkson, G.3    Goedhals, L.4    Hacking, D.5    Rugg, T.A.6
  • 24
    • 0028020890 scopus 로고
    • Phase II study of gemcitabine (2′,2′-difluorodeoxycytidine) in previously treated ovarian cancer patients
    • Lund B, Hansen OP, Theilade K, Hansen M and Neijt JP: Phase II study of gemcitabine (2′,2′-difluorodeoxycytidine) in previously treated ovarian cancer patients. J Natl Cancer Inst 86: 1530-1533, 1994.
    • (1994) J Natl Cancer Inst , vol.86 , pp. 1530-1533
    • Lund, B.1    Hansen, O.P.2    Theilade, K.3    Hansen, M.4    Neijt, J.P.5
  • 26
    • 0030698628 scopus 로고    scopus 로고
    • Phase II study of single-agent gemcitabine in previously untreated patients with metastatic urothelial cancer
    • Stadler WM, Kuzel T, Roth B, Raghavan D and Dorr FA: Phase II study of single-agent gemcitabine in previously untreated patients with metastatic urothelial cancer. J Clin Oncol 15: 3394-3398, 1997.
    • (1997) J Clin Oncol , vol.15 , pp. 3394-3398
    • Stadler, W.M.1    Kuzel, T.2    Roth, B.3    Raghavan, D.4    Dorr, F.A.5
  • 27
    • 0030686593 scopus 로고    scopus 로고
    • Gemcitabine: A promising new agent in the treatment of advanced urothelial cancer
    • Moore MJ, Tannock IF, Ernst DS, Huan S and Murray N: Gemcitabine: a promising new agent in the treatment of advanced urothelial cancer. J Clin Oncol 15: 3441-3445, 1997.
    • (1997) J Clin Oncol , vol.15 , pp. 3441-3445
    • Moore, M.J.1    Tannock, I.F.2    Ernst, D.S.3    Huan, S.4    Murray, N.5
  • 30
    • 0028236635 scopus 로고
    • A late phase II study of CPT-11, irinotecan hydrochloride, in patients with advanced pancreatic cancer
    • CPT-11 study group on gastrointestinal cancer
    • Sakata Y, Shimada Y, Yoshino M, Kambe M, Futatsuki K, Nakao I, Ogawa N, Wakui A and Taguchi T: A late phase II study of CPT-11, irinotecan hydrochloride, in patients with advanced pancreatic cancer. CPT-11 study group on gastrointestinal cancer. Jpn J Cancer Chemother 21: 1039-1046, 1994.
    • (1994) Jpn J Cancer Chemother , vol.21 , pp. 1039-1046
    • Sakata, Y.1    Shimada, Y.2    Yoshino, M.3    Kambe, M.4    Futatsuki, K.5    Nakao, I.6    Ogawa, N.7    Wakui, A.8    Taguchi, T.9
  • 31
    • 0030883212 scopus 로고    scopus 로고
    • Clinical pharmacokinetics of irinotecan
    • Chabot GG: Clinical pharmacokinetics of irinotecan. Clin Pharmacokinet 33: 245-259, 1997
    • (1997) Clin Pharmacokinet , vol.33 , pp. 245-259
    • Chabot, G.G.1
  • 32
    • 0029852961 scopus 로고    scopus 로고
    • Phase I studies with the novel nucleoside analog gemcitabine
    • Abbruzzese JL: Phase I studies with the novel nucleoside analog gemcitabine. Semin Oncol 23: 24-31, 1996.
    • (1996) Semin Oncol , vol.23 , pp. 24-31
    • Abbruzzese, J.L.1
  • 33
    • 0030944603 scopus 로고    scopus 로고
    • In vitro interaction between gemcitabine and other anticancer drugs using a novel three-dimensional model
    • Kanzawa F and Saijo N: In vitro interaction between gemcitabine and other anticancer drugs using a novel three-dimensional model. Semin Oncol 24 (2 Suppl 7): S7-8-S7-16, 1997.
    • (1997) Semin Oncol , vol.24 , Issue.2 SUPPL. 7
    • Kanzawa, F.1    Saijo, N.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.