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Volumn 17, Issue 2, 1999, Pages 585-592

Phase I-II study of gemcitabine and fluorouracil as a continuous infusion in patients with pancreatic cancer

Author keywords

[No Author keywords available]

Indexed keywords

FLUOROURACIL; GEMCITABINE;

EID: 0033012340     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/jco.1999.17.2.585     Document Type: Article
Times cited : (176)

References (26)
  • 2
    • 0029816590 scopus 로고    scopus 로고
    • Chemotherapy improves survival and quality of life in advanced pancreatic and biliary cancer
    • Glimelius B, Hoffman K, Sjödén P-O, et al: Chemotherapy improves survival and quality of life in advanced pancreatic and biliary cancer. Ann Oncol 7:593-600, 1996
    • (1996) Ann Oncol , vol.7 , pp. 593-600
    • Glimelius, B.1    Hoffman, K.2    Sjödén, P.-O.3
  • 3
    • 0023880296 scopus 로고
    • Continuous 5-fluorouacil infusion in carcinoma of the pancreas
    • Hansen R, Quebbman E, Ritch P, et al: Continuous 5-fluorouacil infusion in carcinoma of the pancreas. Am J Med Sci 295:91-93, 1988
    • (1988) Am J Med Sci , vol.295 , pp. 91-93
    • Hansen, R.1    Quebbman, E.2    Ritch, P.3
  • 4
    • 0025815267 scopus 로고
    • Lack of efficacy of high-dose leucovorin and fluorouracil in patients with pancreatic adenocarcinoma
    • Crown J, Casper ES, Botet J, et al: Lack of efficacy of high-dose leucovorin and fluorouracil in patients with pancreatic adenocarcinoma. J Clin Oncol 9:1682-1686, 1991
    • (1991) J Clin Oncol , vol.9 , pp. 1682-1686
    • Crown, J.1    Casper, E.S.2    Botet, J.3
  • 5
    • 0025841867 scopus 로고
    • Fluorouracil and high-dose leucovorin in previously untreated patients with advanced adenocarcinoma of the pancreas: Results of a phase II trial
    • DeCaprio JA, Mayer RJ, Gonin R, et al: Fluorouracil and high-dose leucovorin in previously untreated patients with advanced adenocarcinoma of the pancreas: Results of a phase II trial. J Clin Oncol 9:2128-2133, 1991
    • (1991) J Clin Oncol , vol.9 , pp. 2128-2133
    • DeCaprio, J.A.1    Mayer, R.J.2    Gonin, R.3
  • 6
    • 0028791757 scopus 로고
    • Cisplatin and protracted venous infusion 5-fluorouracil (CF): Good symptom relief with low toxicity in advanced pancreatic carcinoma
    • Nicolson M, Webb A, Cunningham D, et al: Cisplatin and protracted venous infusion 5-fluorouracil (CF): good symptom relief with low toxicity in advanced pancreatic carcinoma. Ann Oncol 6:801-804, 1995
    • (1995) Ann Oncol , vol.6 , pp. 801-804
    • Nicolson, M.1    Webb, A.2    Cunningham, D.3
  • 7
    • 0026066795 scopus 로고
    • Continuous infusion 5-fluorouracil plus weekly cisplatin for pancreatic carcinoma: A Mid-Atlantic Oncology Program study
    • Rothman H, Cantrell JE, Lockich J, et al: Continuous infusion 5-fluorouracil plus weekly cisplatin for pancreatic carcinoma: A Mid-Atlantic Oncology Program study. Cancer 68:264-268, 1991
    • (1991) Cancer , vol.68 , pp. 264-268
    • Rothman, H.1    Cantrell, J.E.2    Lockich, J.3
  • 8
    • 0030878120 scopus 로고    scopus 로고
    • Treatment of advanced pancreatic carcinoma with a combination of protracted infusional 5-fluorouracil and weekly carboplatin: A Mid-Atlantic Oncology Program study
    • Auerbach M, Wampler GL, Lockich JJ, et al: Treatment of advanced pancreatic carcinoma with a combination of protracted infusional 5-fluorouracil and weekly carboplatin: A Mid-Atlantic Oncology Program study. Ann Oncol 8:439-444, 1997
    • (1997) Ann Oncol , vol.8 , pp. 439-444
    • Auerbach, M.1    Wampler, G.L.2    Lockich, J.J.3
  • 9
    • 0025987989 scopus 로고
    • A phase III comparison trial of streptozotocin, mitomycin and 5-fluorouracil with cisplatin, cytosine arabinoside, and caffeine in patients with advanced pancreatic carcinoma
    • Kelsen D, Hudis C, Niedzwiecki D, et al: A phase III comparison trial of streptozotocin, mitomycin and 5-fluorouracil with cisplatin, cytosine arabinoside, and caffeine in patients with advanced pancreatic carcinoma. Cancer 68:965-968, 1991
    • (1991) Cancer , vol.68 , pp. 965-968
    • Kelsen, D.1    Hudis, C.2    Niedzwiecki, D.3
  • 10
    • 0025360261 scopus 로고
    • A phase III trial on the therapy of advanced pancreatic carcinoma: Evaluations of the Mallinson regimen and combined 5-fluorouracil, doxorubicin, and cisplatin
    • Cullinan S, Moertel CG, Wieand HS, et al: A phase III trial on the therapy of advanced pancreatic carcinoma: Evaluations of the Mallinson regimen and combined 5-fluorouracil, doxorubicin, and cisplatin. Cancer 65:2207-2212, 1990
    • (1990) Cancer , vol.65 , pp. 2207-2212
    • Cullinan, S.1    Moertel, C.G.2    Wieand, H.S.3
  • 11
    • 0018615384 scopus 로고
    • Chemotherapy of gastric and pancreatic carcinoma: A controlled evaluation of combination of 5-fluorouracil with nitrosoureas and "lactones."
    • Moertel CG, Engstrom P, Lavin PT, et al: Chemotherapy of gastric and pancreatic carcinoma: A controlled evaluation of combination of 5-fluorouracil with nitrosoureas and "lactones." Surgery 85:509-513, 1979
    • (1979) Surgery , vol.85 , pp. 509-513
    • Moertel, C.G.1    Engstrom, P.2    Lavin, P.T.3
  • 12
    • 0025325071 scopus 로고
    • Evaluation of the antitumor activity of gemcitabine (2′,2′-difluoro-2′-deoxycytidine)
    • Hertel LW, Boder GB, Kroin JS, et al: Evaluation of the antitumor activity of gemcitabine (2′,2′-difluoro-2′-deoxycytidine). Cancer Res 50:4417-4422, 1990
    • (1990) Cancer Res , vol.50 , pp. 4417-4422
    • Hertel, L.W.1    Boder, G.B.2    Kroin, J.S.3
  • 13
    • 0026324313 scopus 로고
    • Action of 2′,2′-difluoro-2′-deoxycytidine on DNA synthesis
    • Huang P, Chubb S, Hertel LW, et al: Action of 2′,2′-difluoro-2′-deoxycytidine on DNA synthesis. Cancer Res 51:6110-6117, 1991
    • (1991) Cancer Res , vol.51 , pp. 6110-6117
    • Huang, P.1    Chubb, S.2    Hertel, L.W.3
  • 14
    • 0028292341 scopus 로고
    • Phase II trial of gemcitabine (2′,2′-difluorodeoxycytidine) in patients with adenocarcinoma of the pancreas
    • Casper ES, Green MR, Kelsen DP, et al: Phase II trial of gemcitabine (2′,2′-difluorodeoxycytidine) in patients with adenocarcinoma of the pancreas. Invest New Drugs 12:29-34, 1994
    • (1994) Invest New Drugs , vol.12 , pp. 29-34
    • Casper, E.S.1    Green, M.R.2    Kelsen, D.P.3
  • 15
    • 8244254377 scopus 로고    scopus 로고
    • Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreatic cancer: A randomized trial
    • Burris HA, Moore MJ, Andersen J, et al: Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreatic cancer: A randomized trial. J Clin Oncol 15:2403-2413, 1997
    • (1997) J Clin Oncol , vol.15 , pp. 2403-2413
    • Burris, H.A.1    Moore, M.J.2    Andersen, J.3
  • 16
    • 8944261362 scopus 로고    scopus 로고
    • A phase II trial of gemcitabine in patients with 5-FU-refractory pancreas cancer
    • Rothemberg ML, Moore MJ, Cripps MC, et al: A phase II trial of gemcitabine in patients with 5-FU-refractory pancreas cancer. Ann Oncol 7:347-353, 1996
    • (1996) Ann Oncol , vol.7 , pp. 347-353
    • Rothemberg, M.L.1    Moore, M.J.2    Cripps, M.C.3
  • 17
    • 0001437359 scopus 로고    scopus 로고
    • Ex vivo ATP tumor testing of gemcitabine for combination chemotherapy and biochemical modulation
    • abstr 2116
    • Bruckner HW, Zhou G, Haenel P, et al: Ex vivo ATP tumor testing of gemcitabine for combination chemotherapy and biochemical modulation. Proc Am Assoc Cancer Res 89:310, 1998 (abstr 2116)
    • (1998) Proc Am Assoc Cancer Res , vol.89 , pp. 310
    • Bruckner, H.W.1    Zhou, G.2    Haenel, P.3
  • 19
    • 0003486931 scopus 로고
    • (WHO Offset Publication No. 48). Geneva, Switzerland, World Health Organization
    • World Health Organization: WHO Handbook for Reporting Results of Cancer Treatment (WHO Offset Publication No. 48). Geneva, Switzerland, World Health Organization, 1979
    • (1979) WHO Handbook for Reporting Results of Cancer Treatment
  • 20
    • 0019850673 scopus 로고
    • Phase I study of protracted venous infusion of 5-fluorouracil
    • Lokich JJ, Bothe A, Fine N, et al: Phase I study of protracted venous infusion of 5-fluorouracil. Cancer 48:2565-2568, 1981
    • (1981) Cancer , vol.48 , pp. 2565-2568
    • Lokich, J.J.1    Bothe, A.2    Fine, N.3
  • 21
    • 0028022127 scopus 로고
    • Gemcitabine: Current status of phase I and II trials
    • Kaye SB: Gemcitabine: Current status of phase I and II trials. J Clin Oncol 12:1527-1531, 1994
    • (1994) J Clin Oncol , vol.12 , pp. 1527-1531
    • Kaye, S.B.1
  • 22
    • 0015962412 scopus 로고
    • Mechanism of interactions of thymidylate synthetase with 5-fluorodeoxyuridylate
    • Santi DV, McHenry CS, Sommer A: Mechanism of interactions of thymidylate synthetase with 5-fluorodeoxyuridylate. Biochemistry 13:471-481, 1974
    • (1974) Biochemistry , vol.13 , pp. 471-481
    • Santi, D.V.1    McHenry, C.S.2    Sommer, A.3
  • 23
    • 0004185252 scopus 로고    scopus 로고
    • Phase I trial of gemcitabine, leucovorin and 5-fluorouracil in patients with advanced malignancies
    • abstr 724
    • Berlin J, Voi M, Alberti D, et al: Phase I trial of gemcitabine, leucovorin and 5-fluorouracil in patients with advanced malignancies. Proc Am Soc Clin Oncol 16:207, 1997 (abstr 724)
    • (1997) Proc Am Soc Clin Oncol , vol.16 , pp. 207
    • Berlin, J.1    Voi, M.2    Alberti, D.3
  • 24
    • 0345230600 scopus 로고    scopus 로고
    • Phase I study of gemcitabine and continuous infusion of 5-fluorouracil in advanced pancreatic cancer
    • abstr 1023
    • Faggiuolo R, Raucci CA, Roncari A, et al: Phase I study of gemcitabine and continuous infusion of 5-fluorouracil in advanced pancreatic cancer. Proc Am Soc Clin Oncol 16:288, 1997 (abstr 1023)
    • (1997) Proc Am Soc Clin Oncol , vol.16 , pp. 288
    • Faggiuolo, R.1    Raucci, C.A.2    Roncari, A.3
  • 25
    • 17344384670 scopus 로고    scopus 로고
    • Cisplatin-gemcitabine combination in advanced non-small cell lung cancer: A phase II study
    • Crino L, Scagliotti G, Marangolo M: Cisplatin-gemcitabine combination in advanced non-small cell lung cancer: A phase II study. J Clin Oncol 15:297-303, 1997
    • (1997) J Clin Oncol , vol.15 , pp. 297-303
    • Crino, L.1    Scagliotti, G.2    Marangolo, M.3
  • 26
    • 0000601979 scopus 로고    scopus 로고
    • Gemcitabine (GEM) and 5-fluorouracil (5-FU) in advanced pancreatic cancer: A GISCAP phase II study
    • abstr 1013
    • Cascinu S, Silva RR, Barni S, et al: Gemcitabine (GEM) and 5-fluorouracil (5-FU) in advanced pancreatic cancer: A GISCAP phase II study. Proc Am Soc Clin Oncol 17:264, 1998 (abstr 1013)
    • (1998) Proc Am Soc Clin Oncol , vol.17 , pp. 264
    • Cascinu, S.1    Silva, R.R.2    Barni, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.