Interaction of acetylcholinesterase with the G4 domain of the laminin α1-chain

Biochemical Journal

Volumn 411, Issue 3, 2008, Pages 507-514

  Johnson, Glynis ^a   Swart, Chrisna ^a   Moore, Samuel W ^a  

^a UNIVERSITY OF STELLENBOSCH   (South Africa)

Author keywords

Acetylcholinesterase; Cell adhesion; Docking; Heparin; Laminin; Peripheral anionic site (PAS)

Indexed keywords

ANTIBODIES; CELL ADHESION; HYDROLYSIS; RATS;

ACETYLCHOLINESTERASE; NEUNTE OUTGROWTH; PERIPHERAL ANIONIC SITE (PAS);

ENZYME ACTIVITY;

ACETYLCHOLINESTERASE; DOCKING PROTEIN; HEPARIN; LAMININ 1; LAMININ BINDING PROTEIN; SYNTHETIC PEPTIDE; AG 73; ANION; EPITOPE; LAMININ; LAMININ A; MONOCLONAL ANTIBODY; PEPTIDE FRAGMENT; UNCLASSIFIED DRUG;

ARTICLE; CELL ADHESION; CONFORMATIONAL TRANSITION; ENZYME BINDING; ENZYME LINKED IMMUNOSORBENT ASSAY; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; AMINO ACID SEQUENCE; ANIMAL; BINDING COMPETITION; CHEMICAL STRUCTURE; CHEMISTRY; HUMAN; IMMUNOLOGY; METABOLISM; MOLECULAR GENETICS; MOUSE; PROTEIN BINDING; PROTEIN QUATERNARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; SEQUENCE ALIGNMENT;

ACETYLCHOLINESTERASE; AMINO ACID SEQUENCE; ANIMALS; ANIONS; ANTIBODIES, MONOCLONAL; BINDING, COMPETITIVE; EPITOPES; HEPARIN; HUMANS; LAMININ; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ALIGNMENT;

EID: 42449164646     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20071404     Document Type: Article

References (48)

1. Soreq, H. and Seidman, S. (2001) Acetylcholinesterase: new roles for an old actor. Nat. Rev. Neurosci. 2, 294-302
2. Inestrosa, N. C., Sagal, J. P. and Colombres, M. (2005) Acetylcholinesterase: interaction with Alzheimer amyloid β. Subcell. Biochem. 38, 299-317
3. Zhang, X. J., Yang, L., Zhao, Q., Caen, J. P., He, H. Y., Jin, Q. H., Guo, L. H., Alemany, M., Zhang, L. Y. and Shi, Y. F. (2002) Induction of acetylcholinesterase expression during apoptosis in various cell types. Cell Death Differ. 9, 790-800
4. Pera, M., Roman, S., Ratia, M., Camps, P., Munoz-Torrero, D., Colombo, L., Manzoni, C., Salmona, M., Badia, A. and Clos, M. V. (2006) Acetylcholinesterase triggers the aggregation of PrP 106-126. Biochem. Biophys. Res. Commun. 346, 89-94
5. Johnson, G. and Moore, S. W. (2003) Human acetylcholinesterase binds to mouse laminin-1 and collagen IV by an electrostatic mechanism at the peripheral anionic site. Neurosci. Lett. 337, 37-40
6. Paraoanu, L. E. and Layer, P. G. (2004) Mouse acetylcholinesterase interacts in yeast with the extracellular matrix component laminin-1β. FEBS Lett. 576, 161-164
7. Giordano, C., Poiana, G., Augusti-Tocco, G. and Biagioni, S. (2007) Acetylcholinesterase modulates neurite outgrowth on fibronectin. Biochem. Biophys. Res. Commun. 356, 398-404
8. Greenfield, S. A., Day, T., Mann, E. O. and Bermudez, I. (2004) A novel peptide modulates α7 nicotinic receptor responses: implications for a possible trophic-toxic mechanism within the brain. J. Neurochem. 90, 325-331
9. De Ferrari, G. V., Canales, M. A., Shin, I., Weiner, L. M., Silman, I. and Inestrosa, N. C. (2001) A structural motif of acetylcholinesterase that promotes amyloid β-peptide fibril formation. Biochemistry 40, 10447-10457
10. Johnson, G. and Moore, S. W. (2004) Identification of a structural site on acetylcholinesterase that promotes neurite outgrowth and binds laminin-1 and collagen IV. Biochem. Biophys. Res. Commun. 319, 448-455
11. Day, T. and Greenfield, S. A. (2003) A peptide derived from acetylcholinesterase induces neuronal death: characterisation of possible mechanisms. Exp. Brain Res. 154, 334-342
12. Dori, A. and Soreq, H. (2006) ARP, the cleavable C-terminal peptide of 'readthrough' acetylcholinesterase, promotes neuronal development and plasticity. J. Mol. Neurosci. 28, 247-255
13. Aumailley, M., Bruckner-Tuderman, L., Carter, W. G., Deutzmann, R., Edgar, D., Ekblom, P., Engel, J., Engvall, E., Hohenester, E., Jones, J. C. R. et al. (2005) A simplified laminin nomenclature. Matrix Biol. 24, 326-332
14. Duband, J. L. and Thiery, J. P. (1987) Distribution of laminin and collagens during avian neural crest cell development. Development 101, 461-478
15. Drews, U. (1975) Cholinesterase in embryonic development. Prog. Histochem. Cytochem. 7, 1-52
16. Tzu, J. and Marinkovich, M. P. (2007) Bridging structure with function: structural, regulatory and developmental role of laminins. Int. J. Biochem. Cell Biol. 40, 199-214
17. Suzuki, N., Yokoyama, F. and Nomizu, M. (2005) Functional sites in the laminin alpha chains. Connect. Tissue Res. 46, 142-152
18. Powell, S. K. and Kleinman, H. K. (1997) Neuronal laminins and their cellular receptors. Int. J. Biochem. Cell Biol. 29, 401-414
19. Nomizu, M., Kim, W. H., Yamamura, K., Utani, A., Song, S.-Y., Otaka, A., Roller, P. P., Kleinman, H. K. and Yamada, Y. (1995) Identification of cell binding sites in the laminin α1 chain carboxyl-terminal globular domain by systematic screening of synthetic peptides. J. Biol. Chem. 270, 20583-20590
20. Johnson, G. and Moore, S. W. (2000) Cholinesterases modulate cell adhesion in human neuroblastoma cells in vitro. Int. J. Dev. Neurosci. 18, 781-790
21. Olivera, S., Rodriguez-Ithurralde, D. and Henley, J. M. (2003) Acetylcholinesterase promotes neurite elongation, synapse formation and surface expression of AMDA receptors in hippocampal neurons. Mol. Cell. Neurosci. 23, 96-106
22. De Jaco, A., Augusti-Tocco, G. and Biagioni, S. (2002) Alternative acetylcholinesterase molecular forms exhibit similar ability to induce neurite outgrowth. J. Neurosci. Res. 70, 756-765
23. Karpel, R., Sternfeld, M., Ginzberg, D., Guhl, E., Graessmann, A. and Soreq, H. (1996) Overexpression of alternative human acetylcholinesterase forms modulates process extensions in cultured glioma cells. J. Neurochem. 66, 114-123
24. Ferrand, C., Clarons, D., Delteil, C. and Weber, M. J. (1986) Cellular localization of the molecular forms of acetylcholinesterase in primary cultures of rat sympathetic neurons and analysis of the secreted enzyme. J. Neurochem. 46, 349-358
25. Botti, S. A., Felder, C. E., Sussman, J. L. and Silman, I. (1998) Electrotactins: a class of adhesion proteins with conserved electrostatic and structural motifs. Protein Eng. 11, 415-420
26. Bourne, Y., Radic, Z., Sulzenbacher, G., Kim, E., Taylor, P. and Marchot, P. (2006) Substrate and product trafficking through the active center gorge of acetylcholinesterase analysed by crystallography and equilibrium binding. J. Biol. Chem. 281, 29256-29267
27. Colletier, J. P., Fournier, D., Greenblatt, H. M., Stojan, J., Sussman, J. L., Zaccai, G., Silman, I. and Weik, M. (2006) Structural insights into substrate traffic and inhibitors in acetylcholinesterase. EMBO J. 25, 2746-2756
28. Bourne, Y., Radic, Z., Kolb, H. C., Sharpless, K. B., Taylor, P. and Marchot, P. (2005) Structural insights into conformational flexibility at the peripheral site and within the active center gorge of acetylcholinesterase. Chem. Biol. Interact. 157-158, 159-165
29. Munoz, F. J., Aldunate, R. and Inestrosa, N. C. (1999) Peripheral binding site is involved in the neurotrophic activity of acetylcholinesterase. NeuroReport 10, 3621-3625
30. Harlow, E. and Lane, D. (1988) Antibodies: A Laboratory Manual, Cold Spring Harbor Laboratory Press, Cold Spring Harbor
31. Johnson, G. and Moore, S. W. (2002) Catalytic antibodies with acetylcholinesterase activity. J. Immunol. Methods 269, 13-28
32. Bhakdi, S., Roth, M. and Hugo, F. (1989) Biotinylation: a simple method for labelling complement component C8 with preservation of functional activity. J. Immunol. Methods 121, 61-66
33. Harrison, D., Hussain, S. A., Combs, A. C., Ervasti, J. M., Yurchenco, P. D. and Hohenester, E. (2007) Crystal structure and cell surface anchorage sites of laminin α1 G4-5. J. Biol. Chem. 282, 11573-11581
34. Hopp, T. P. and Woods, K. R. (1983) A computer program for predicting protein antigenic determinants. Mol. Immunol. 20, 483-489
35. Wasserman, L., Doctor, B. P., Gentry, M. K. and Taylor, P. (1993) Epitope mapping of form-specific and nonspecific antibodies to acetylcholinesterase. J. Neurochem. 61, 2124-2132
36. Wewer, U. M. and Engvall, E. (1996) Merosin/laminin-2 and muscular dystrophy. Neuromuscul. Disord. 6, 409-418
37. Hoffman, M. P., Nomizu, M., Roque, E., Lee, S., Jung, D. W., Yamada, Y. and Kleinman, H. K. (1998) Laminin-1 and laminin-2 G-domain synthetic peptides bind syndecan-1 and are involved in acinar formation of a human submandibular gland cell line. J. Biol. Chem. 273, 28633-28641
38. Andac, Z., Sasaki, T., Mann, K., Brancaccio, A., Deutzmann, R. and Timpl, R. (1999) Analysis of heparin, α-dystroglycan and sulfatide binding to the G domain of the laminin α1 chain by site-directed mutagenesis. J. Mol. Biol. 287, 253-264
39. Ma, B., Shatsky, M., Wolfson, H. J. and Nussinov, R. (2002) Multiple diverse ligands binding at a single protein site: a matter of pre-existing populations. Protein Sci. 11, 184-197
40. Wyman, Jr, J. (1964) Linked functions and reciprocal effects in hemoglobin: a second look. Adv. Protein Chem. 19, 223-286
41. Xie, W., Stribley, J. A., Chatonnet, A., Wilder, P. J., Rizzino, A., McComb, R. D., Taylor, P., Hinrichs, S. H. and Lockridge, O. (2000) Postnatal developmental delay and supersensitivity to organophosphate in gene-targeted mice lacking acetylcholinesterase. J. Pharmacol. Exp. Ther. 292, 896-902
42. Cousin, X., Strahle, U. and Chatonnet, A. (2005) Are there non-catalytic functions of acetylcholinesterases? Lessons from mutant animal models. BioEssays 27, 189-200
43. Biagioni, S., Tata, A. M., De Jaco, A. and Augusti-Tocco, G. (2000) Acetylcholine synthesis and neuron differentiation. Int. J. Dev. Biol. 44, 689-697
44. Sharma, K. V. and Bigbee, J. W. (1998) Acetylcholinesterase antibody treatment results in neurite detachment and reduced outgrowth from cultured neurons: further evidence for a cell adhesive role for neuronal acetylcholinesterase. J. Neurosci. Res. 53, 454-464
45. Richard, B. L., Nomizu, M., Yamada, Y. and Kleinman, H. K. (1996) Identification of synthetic peptides derived from laminin α1 and α2 chains with cell type specificity for neurite outgrowth. Exp. Cell Res. 228, 98-105
46. Kim, C. W., Goldberger, O. A., Gallo, R. L. and Bernfield, M. (1994) Members of the syndecan family of heparan sulfate proteoglycans are expressed in distinct cell-, tissue-, and development-specific forms. Mol. Biol. Cell 5, 797-805
47. Hartmann, U. and Maurer, P. (2001) Proteoglycans in the nervous system: the quest for functional roles in vivo. Matrix Biol. 20, 23-35
48. Grifman, M., Galyam, N., Seidman, S. and Soreq, H. (1998) Functional redundancy of acetylcholinesterase and neuroligin in mammalian neuritogenesis. Proc. Natl. Acad. Sci. U.S.A. 95, 13935-13940