메뉴 건너뛰기




Volumn 27, Issue 2, 2005, Pages 189-200

Are there non-catalytic functions of acetylcholinesterases? Lessons from mutant animal models

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; ACETYLCHOLINESTERASE; CHOLINERGIC RECEPTOR; CHOLINESTERASE;

EID: 14344255818     PISSN: 02659247     EISSN: None     Source Type: Journal    
DOI: 10.1002/bies.20153     Document Type: Review
Times cited : (54)

References (100)
  • 1
    • 0032936983 scopus 로고    scopus 로고
    • Development of the vertebrate neuromuscular junction
    • Sanes JR, Lichtman JW. 1999. Development of the vertebrate neuromuscular junction. Annu Rev Neurosci 22:389-442.
    • (1999) Annu Rev Neurosci , vol.22 , pp. 389-442
    • Sanes, J.R.1    Lichtman, J.W.2
  • 2
    • 0036891517 scopus 로고    scopus 로고
    • Building the vertebrate neuromuscular synapse
    • Burden SJ. 2002. Building the vertebrate neuromuscular synapse. J Neurobiol 53:501-511.
    • (2002) J Neurobiol , vol.53 , pp. 501-511
    • Burden, S.J.1
  • 3
    • 0033362102 scopus 로고    scopus 로고
    • Congenital end-plate acetylcholinesterase deficiency caused by a nonsense mutation and an A→G splice-donor-site mutation at position +3 of the collagenlike-tail-subunit gene (COLQ): How does G at position +3 result in aberrant splicing?
    • Ohno K, Brengman JM, Felice KJ, Cornblath DR, Engel AG. 1999. Congenital end-plate acetylcholinesterase deficiency caused by a nonsense mutation and an A→G splice-donor-site mutation at position +3 of the collagenlike-tail- subunit gene (COLQ): how does G at position +3 result in aberrant splicing? Am J Hum Genet 65:635-644.
    • (1999) Am J Hum Genet , vol.65 , pp. 635-644
    • Ohno, K.1    Brengman, J.M.2    Felice, K.J.3    Cornblath, D.R.4    Engel, A.G.5
  • 4
    • 17344391484 scopus 로고    scopus 로고
    • The spectrum of mutations causing end-plate acetylcholinesterase deficiency
    • Ohno K, Engel AG, Brengman JM, Shen XM, Heidenreich F, et al. 2000. The spectrum of mutations causing end-plate acetylcholinesterase deficiency. Ann Neurol 47:162-170.
    • (2000) Ann Neurol , vol.47 , pp. 162-170
    • Ohno, K.1    Engel, A.G.2    Brengman, J.M.3    Shen, X.M.4    Heidenreich, F.5
  • 5
    • 0037160130 scopus 로고    scopus 로고
    • Single nucleotide polymorphism of the human high affinity choline transporter alters transport rate
    • Okuda T, Okamura M, Kaitsuka C, Haga T, Gurwitz D. 2002. Single nucleotide polymorphism of the human high affinity choline transporter alters transport rate. J Biol Chem 277:45315-45322.
    • (2002) J Biol Chem , vol.277 , pp. 45315-45322
    • Okuda, T.1    Okamura, M.2    Kaitsuka, C.3    Haga, T.4    Gurwitz, D.5
  • 6
    • 0036310759 scopus 로고    scopus 로고
    • Congenital myasthenic syndrome associated with episodic apnea and sudden infant death
    • Byring RF, Pihko H, Tsujino A, Shen XM, Gustafsson B, et al. 2002. Congenital myasthenic syndrome associated with episodic apnea and sudden infant death. Neuromuscul Disord 12:548-553.
    • (2002) Neuromuscul Disord , vol.12 , pp. 548-553
    • Byring, R.F.1    Pihko, H.2    Tsujino, A.3    Shen, X.M.4    Gustafsson, B.5
  • 8
    • 0842304284 scopus 로고    scopus 로고
    • The cholinergic lesion of Alzheimer's disease: Pivotal factor or side show?
    • Mesulam M. 2004. The cholinergic lesion of Alzheimer's disease: pivotal factor or side show? Learn Mem 11:43-49.
    • (2004) Learn Mem , vol.11 , pp. 43-49
    • Mesulam, M.1
  • 9
    • 0346494961 scopus 로고    scopus 로고
    • ESTHER, the database of the alpha/beta-hydrolase fold superfamily of proteins
    • Hotelier T, Renault L, Cousin X, Negre V, Marchot P, et al. 2004. ESTHER, the database of the alpha/beta-hydrolase fold superfamily of proteins. Nucleic Acids Res 32:D145-D147.
    • (2004) Nucleic Acids Res , vol.32
    • Hotelier, T.1    Renault, L.2    Cousin, X.3    Negre, V.4    Marchot, P.5
  • 10
    • 0036560908 scopus 로고    scopus 로고
    • The origin of the molecular diversity and functional anchoring of cholinesterases
    • Massoulié J. 2002. The origin of the molecular diversity and functional anchoring of cholinesterases. Neurosignals 11:130-143.
    • (2002) Neurosignals , vol.11 , pp. 130-143
    • Massoulié, J.1
  • 11
    • 0023099099 scopus 로고
    • A morphogenic role for transiently expressed acetylcholinesterase in developing thalamocortical systems?
    • Robertson RT. 1987. A morphogenic role for transiently expressed acetylcholinesterase in developing thalamocortical systems? Neurosci Lett 75:259-264.
    • (1987) Neurosci Lett , vol.75 , pp. 259-264
    • Robertson, R.T.1
  • 12
    • 0021044291 scopus 로고
    • Comparative localization of acetylcholinesterase and pseudocholinesterase during morphogenesis of the chicken brain
    • Layer PG. 1983. Comparative localization of acetylcholinesterase and pseudocholinesterase during morphogenesis of the chicken brain. Proc Natl Acad Sci USA 80:6413-6417.
    • (1983) Proc Natl Acad Sci USA , vol.80 , pp. 6413-6417
    • Layer, P.G.1
  • 13
    • 0025490658 scopus 로고
    • Cholinesterases preceding major tracts in vertebrate neurogenesis
    • Layer PG. 1990. Cholinesterases preceding major tracts in vertebrate neurogenesis. Bioessays 12:415-420.
    • (1990) Bioessays , vol.12 , pp. 415-420
    • Layer, P.G.1
  • 14
    • 0032559867 scopus 로고    scopus 로고
    • Developmental expression of acetyl- And butyrylcholinesterase in the rat: Enzyme and mRNA levels in embryonic dorsal root ganglia
    • Koenigsberger C, Hammond P, Brimijoin S. 1998. Developmental expression of acetyl- and butyrylcholinesterase in the rat: enzyme and mRNA levels in embryonic dorsal root ganglia. Brain Res 787:248-258.
    • (1998) Brain Res , vol.787 , pp. 248-258
    • Koenigsberger, C.1    Hammond, P.2    Brimijoin, S.3
  • 15
    • 0026447003 scopus 로고
    • Secreted acetylcholinesterase: Non-classical aspects of a classical enzyme
    • Appleyard ME. 1992. Secreted acetylcholinesterase: non-classical aspects of a classical enzyme. Trends Neurosci 15:485-490.
    • (1992) Trends Neurosci , vol.15 , pp. 485-490
    • Appleyard, M.E.1
  • 16
    • 0035808323 scopus 로고    scopus 로고
    • Zebrafish acetylcholinesterase is encoded by a single gene localized on linkage group 7. Gene structure and polymorphism; molecular forms and expression pattern during development
    • Bertrand C, Chatonnet A, Takke C, Van YL, Postlethwait J, et al. 2001. Zebrafish acetylcholinesterase is encoded by a single gene localized on linkage group 7. Gene structure and polymorphism; molecular forms and expression pattern during development. J Biol Chem 276:464-474.
    • (2001) J Biol Chem , vol.276 , pp. 464-474
    • Bertrand, C.1    Chatonnet, A.2    Takke, C.3    Van, Y.L.4    Postlethwait, J.5
  • 17
    • 0029860131 scopus 로고    scopus 로고
    • From oocyte to neuron: Do neurotransmitters function in the same way throughout development?
    • Buznikov GA, Shmukler YB, Lauder JM. 1996. From oocyte to neuron: do neurotransmitters function in the same way throughout development? Cell Mol Neurobiol 16:537-559.
    • (1996) Cell Mol Neurobiol , vol.16 , pp. 537-559
    • Buznikov, G.A.1    Shmukler, Y.B.2    Lauder, J.M.3
  • 18
    • 0032908629 scopus 로고    scopus 로고
    • Morphogenetic roles of acetylcholine
    • Lauder JM, Schambra UB. 1999. Morphogenetic roles of acetylcholine. Environ Health Perspect 107(Suppl 1):65-69.
    • (1999) Environ Health Perspect , vol.107 , Issue.SUPPL. 1 , pp. 65-69
    • Lauder, J.M.1    Schambra, U.B.2
  • 19
    • 0036006876 scopus 로고    scopus 로고
    • Three-dimensional mapping of cholinergic molecules by confocal laser scanning microscopy in sea urchin larvae
    • Falugi C, Diaspro A, Angelini C, Pedrotti ML, Raimondo M, et al. 2002. Three-dimensional mapping of cholinergic molecules by confocal laser scanning microscopy in sea urchin larvae. Micron 33:233-239.
    • (2002) Micron , vol.33 , pp. 233-239
    • Falugi, C.1    Diaspro, A.2    Angelini, C.3    Pedrotti, M.L.4    Raimondo, M.5
  • 20
    • 0031587286 scopus 로고    scopus 로고
    • Acetylcholinesterase promotes the aggregation of amyloid-beta-peptide fragments by forming a complex with the growing fibrils
    • Alvarez A, Opazo C, Alarcon R, Garrido J, Inestrosa NC. 1997. Acetylcholinesterase promotes the aggregation of amyloid-beta-peptide fragments by forming a complex with the growing fibrils. J Mol Biol 272:348-361.
    • (1997) J Mol Biol , vol.272 , pp. 348-361
    • Alvarez, A.1    Opazo, C.2    Alarcon, R.3    Garrido, J.4    Inestrosa, N.C.5
  • 21
    • 0030873431 scopus 로고    scopus 로고
    • Acetylcholinesterase-transgenic mice display embryonic modulations in spinal cord choline acetyltransferase and neurexin Ibeta gene expression followed by late-onset neuromotor deterioration
    • Andres C, Beeri R, Friedman A, Lev-Lehman E, Henis S, et al. 1997. Acetylcholinesterase-transgenic mice display embryonic modulations in spinal cord choline acetyltransferase and neurexin Ibeta gene expression followed by late-onset neuromotor deterioration. Proc Natl Acad Sci USA 94:8173-8178.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 8173-8178
    • Andres, C.1    Beeri, R.2    Friedman, A.3    Lev-Lehman, E.4    Henis, S.5
  • 22
    • 0029360450 scopus 로고
    • Transgenic expression of human acetylcholinesterase induces progressive cognitive deterioration in mice
    • Beeri R, Andres C, Lev-Lehman E, Timberg R, Huberman T, et al. 1995. Transgenic expression of human acetylcholinesterase induces progressive cognitive deterioration in mice. Current Biology 5:1063-1071.
    • (1995) Current Biology , vol.5 , pp. 1063-1071
    • Beeri, R.1    Andres, C.2    Lev-Lehman, E.3    Timberg, R.4    Huberman, T.5
  • 23
    • 0035320772 scopus 로고    scopus 로고
    • Acetylcholinesterase-new roles for an old actor
    • Soreq H, Seidman S. 2001. Acetylcholinesterase-new roles for an old actor. Nat Rev Neurosci 2:294-302.
    • (2001) Nat Rev Neurosci , vol.2 , pp. 294-302
    • Soreq, H.1    Seidman, S.2
  • 24
    • 0028819272 scopus 로고
    • Cholinergic regulation of neurite outgrowth from isolated chick sympathetic neurons in culture
    • Small DH, Reed G, Whitefield B, Nurcombe V. 1995. Cholinergic regulation of neurite outgrowth from isolated chick sympathetic neurons in culture. J Neurosci 15:144-151.
    • (1995) J Neurosci , vol.15 , pp. 144-151
    • Small, D.H.1    Reed, G.2    Whitefield, B.3    Nurcombe, V.4
  • 25
    • 0035863556 scopus 로고    scopus 로고
    • Direct evidence for an adhesive function in the noncholinergic role of acetylcholinesterase in neurite outgrowth
    • Sharma KV, Koenigsberger C, Brimijoin S, Bigbee JW. 2001. Direct evidence for an adhesive function in the noncholinergic role of acetylcholinesterase in neurite outgrowth. J Neurosci Res 63:165-175.
    • (2001) J Neurosci Res , vol.63 , pp. 165-175
    • Sharma, K.V.1    Koenigsberger, C.2    Brimijoin, S.3    Bigbee, J.W.4
  • 26
    • 0031663777 scopus 로고    scopus 로고
    • Butyrylcholinesterase antisense transfection increases apoptosis in differentiating retinal reaggregates of the chick embryo
    • Robitzki A, Mack A, Hoppe U, Chatonnet A, Layer PG. 1998. Butyrylcholinesterase antisense transfection increases apoptosis in differentiating retinal reaggregates of the chick embryo. J Neurochem 71: 1413-1420.
    • (1998) J Neurochem , vol.71 , pp. 1413-1420
    • Robitzki, A.1    Mack, A.2    Hoppe, U.3    Chatonnet, A.4    Layer, P.G.5
  • 27
    • 0034131817 scopus 로고    scopus 로고
    • Evidence for a noncholinergic function of acetylcholinesterase during development of chicken retina as shown by fasciculin
    • Blasina MF, Faria AC, Gardino PF, Hokoc JN, Almeida OM, et al. 2000. Evidence for a noncholinergic function of acetylcholinesterase during development of chicken retina as shown by fasciculin. Cell Tissue Res 299:173-184.
    • (2000) Cell Tissue Res , vol.299 , pp. 173-184
    • Blasina, M.F.1    Faria, A.C.2    Gardino, P.F.3    Hokoc, J.N.4    Almeida, O.M.5
  • 28
    • 0034647050 scopus 로고    scopus 로고
    • Evidence for the direct role of acetylcholinesterase in neurite outgrowth in primary dorsal root ganglion neurons
    • Bigbee JW, Sharma KV, Chan EL, Bogler O. 2000. Evidence for the direct role of acetylcholinesterase in neurite outgrowth in primary dorsal root ganglion neurons. Brain Res 861:354-362.
    • (2000) Brain Res , vol.861 , pp. 354-362
    • Bigbee, J.W.1    Sharma, K.V.2    Chan, E.L.3    Bogler, O.4
  • 29
    • 0031842365 scopus 로고    scopus 로고
    • Influence of acetylcholinesterase on embryonic spinal rat motoneurones growth in culture: A quantitative morphometric study
    • Bataille S, Portalier P, Coulon P, Ternaux JP. 1998. Influence of acetylcholinesterase on embryonic spinal rat motoneurones growth in culture: a quantitative morphometric study. Eur J Neurosci 10:560-572.
    • (1998) Eur J Neurosci , vol.10 , pp. 560-572
    • Bataille, S.1    Portalier, P.2    Coulon, P.3    Ternaux, J.P.4
  • 30
    • 0033607448 scopus 로고    scopus 로고
    • Peripheral binding site is involved in the neurotrophic activity of acetylcholinesterase
    • Munoz FJ, Aldunate R, Inestrosa NC. 1999. Peripheral binding site is involved in the neurotrophic activity of acetylcholinesterase. Neuroreport 10:3621-3625.
    • (1999) Neuroreport , vol.10 , pp. 3621-3625
    • Munoz, F.J.1    Aldunate, R.2    Inestrosa, N.C.3
  • 31
    • 0029163984 scopus 로고
    • Novel functions of cholinesterases in development, physiology and disease
    • Layer PG, Willbold E. 1995. Novel functions of cholinesterases in development, physiology and disease. Progress Histochem Cytochem 29: 1-94.
    • (1995) Progress Histochem Cytochem , vol.29 , pp. 1-94
    • Layer, P.G.1    Willbold, E.2
  • 32
    • 0027198071 scopus 로고
    • Cholinesterases regulate neurite growth of chick nerve cells in vitro by means of a non-enzymatic mechanism
    • Layer PG, Weikert T, Alber R. 1993. Cholinesterases regulate neurite growth of chick nerve cells in vitro by means of a non-enzymatic mechanism. Cell Tissue Res 273:219-226.
    • (1993) Cell Tissue Res , vol.273 , pp. 219-226
    • Layer, P.G.1    Weikert, T.2    Alber, R.3
  • 33
    • 0344441446 scopus 로고    scopus 로고
    • A peptide derived from acetylcholinesterase induces neuronal cell death: Characterisation of possible mechanisms
    • Day T, Greenfield SA. 2003. A peptide derived from acetylcholinesterase induces neuronal cell death: characterisation of possible mechanisms. Exp Brain Res 153:334-342.
    • (2003) Exp Brain Res , vol.153 , pp. 334-342
    • Day, T.1    Greenfield, S.A.2
  • 34
    • 0242317361 scopus 로고    scopus 로고
    • Making connections: Cholinesterase-domain proteins in the CNS
    • Scholl FG, Scheiffele P. 2003. Making connections: cholinesterase-domain proteins in the CNS. Trends Neurosci 26:618-624.
    • (2003) Trends Neurosci , vol.26 , pp. 618-624
    • Scholl, F.G.1    Scheiffele, P.2
  • 35
    • 0029816374 scopus 로고    scopus 로고
    • The structure-function relationships in Drosophila neurotactin show that cholinesterasic domains may have adhesive properties
    • Darboux I, Barthalay Y, Piovant M, Hipeau-Jacquotte R. 1996. The structure-function relationships in Drosophila neurotactin show that cholinesterasic domains may have adhesive properties. Embo J 15: 4835-4843.
    • (1996) Embo J , vol.15 , pp. 4835-4843
    • Darboux, I.1    Barthalay, Y.2    Piovant, M.3    Hipeau-Jacquotte, R.4
  • 36
    • 0032506149 scopus 로고    scopus 로고
    • Functional redundancy of acetylcholinesterase and neuroligin in mammalian neuritogenesis
    • Grifman M, Galyam N, Seidman S, Soreq H. 1998. Functional redundancy of acetylcholinesterase and neuroligin in mammalian neuritogenesis. Proc Natl Acad Sci USA 95:13935-13940.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 13935-13940
    • Grifman, M.1    Galyam, N.2    Seidman, S.3    Soreq, H.4
  • 37
    • 0017194820 scopus 로고
    • Genetics of acetylcholinesterase in Drosophila melanogaster
    • Hall JC, Kankel DR. 1976. Genetics of acetylcholinesterase in Drosophila melanogaster. Genetics 83:517-535.
    • (1976) Genetics , vol.83 , pp. 517-535
    • Hall, J.C.1    Kankel, D.R.2
  • 38
    • 0019105940 scopus 로고
    • Behavioral and biochemical defects in temperature-sensitive acetylcholinesterase mutants of Drosophila melanogaster
    • Hall JC, Alahiotis SN, Strumpf DA, White K. 1980. Behavioral and biochemical defects in temperature-sensitive acetylcholinesterase mutants of Drosophila melanogaster. Genetics 96:939-965.
    • (1980) Genetics , vol.96 , pp. 939-965
    • Hall, J.C.1    Alahiotis, S.N.2    Strumpf, D.A.3    White, K.4
  • 39
    • 0018889608 scopus 로고
    • Acetylcholinesterase mutants in Drosophila and their effects on the structure and function of the central nervous system
    • Greenspan RJ, Finn JA Jr., Hall JC. 1980. Acetylcholinesterase mutants in Drosophila and their effects on the structure and function of the central nervous system. J Comp Neurol 189:741-774.
    • (1980) J Comp Neurol , vol.189 , pp. 741-774
    • Greenspan, R.J.1    Finn Jr., J.A.2    Hall, J.C.3
  • 40
    • 0023985973 scopus 로고
    • The acetylcholinesterase genes of C. elegans: Identification of a third gene (ace-3) and mosaic mapping of a synthetic lethal phenotype
    • Johnson CD, Rand JB, Herman RK, Stern BD, Russell RL. 1988. The acetylcholinesterase genes of C. elegans: identification of a third gene (ace-3) and mosaic mapping of a synthetic lethal phenotype. Neuron 1:165-173.
    • (1988) Neuron , vol.1 , pp. 165-173
    • Johnson, C.D.1    Rand, J.B.2    Herman, R.K.3    Stern, B.D.4    Russell, R.L.5
  • 41
    • 0019525546 scopus 로고
    • An acetylcholinesterase-deficient mutant of the nematode Caenorhabditis elegans
    • Johnson CD, Duckett JG, Culotti JG, Herman RK, Meneely PM, et al. 1981. An acetylcholinesterase-deficient mutant of the nematode Caenorhabditis elegans. Genetics 97:261-279.
    • (1981) Genetics , vol.97 , pp. 261-279
    • Johnson, C.D.1    Duckett, J.G.2    Culotti, J.G.3    Herman, R.K.4    Meneely, P.M.5
  • 42
    • 0019525053 scopus 로고
    • A second class of acetylcholinesterase-deficient mutants of the nematode Caenorhabditis elegans
    • Culotti JG, Von Ehrenstein G, Culotti MR, Russell RL. 1981. A second class of acetylcholinesterase-deficient mutants of the nematode Caenorhabditis elegans. Genetics 97:281-305.
    • (1981) Genetics , vol.97 , pp. 281-305
    • Culotti, J.G.1    Von Ehrenstein, G.2    Culotti, M.R.3    Russell, R.L.4
  • 43
    • 0036164239 scopus 로고    scopus 로고
    • Acetylcholinesterase is required for neuronal and muscular development in the zebrafish embryo
    • Behra M, Cousin X, Bertrand C, Vonesch JL, Biellmann D. 2002. Acetylcholinesterase is required for neuronal and muscular development in the zebrafish embryo. Nat Neurosci 5:111-118.
    • (2002) Nat Neurosci , vol.5 , pp. 111-118
    • Behra, M.1    Cousin, X.2    Bertrand, C.3    Vonesch, J.L.4    Biellmann, D.5
  • 44
    • 2342655065 scopus 로고    scopus 로고
    • Acetylcholinesterase function is dispensable for sensory neurite growth but is critical for neuromuscular synapse stability
    • Downes GB, Granato M. 2004. Acetylcholinesterase function is dispensable for sensory neurite growth but is critical for neuromuscular synapse stability. Dev Biol 270:232-245.
    • (2004) Dev Biol , vol.270 , pp. 232-245
    • Downes, G.B.1    Granato, M.2
  • 45
    • 0034119973 scopus 로고    scopus 로고
    • Postnatal developmental delay and supersensitivity to organophosphate in gene-targeted mice lacking acetylcholinesterase
    • Xie W, Stribley JA, Chatonnet A, Wilder PJ, Rizzino A. 2000. Postnatal developmental delay and supersensitivity to organophosphate in gene-targeted mice lacking acetylcholinesterase. J Pharmacol Exp Ther 293:896-902.
    • (2000) J Pharmacol Exp Ther , vol.293 , pp. 896-902
    • Xie, W.1    Stribley, J.A.2    Chatonnet, A.3    Wilder, P.J.4    Rizzino, A.5
  • 46
    • 0037079059 scopus 로고    scopus 로고
    • Roles of neurotransmitter in synapse formation: Development of neuromuscular junctions lacking choline acetyltransferase
    • Misgeld T, Burgess RW, Lewis RM, Cunningham JM, Lichtman JW, et al. 2002. Roles of neurotransmitter in synapse formation: development of neuromuscular junctions lacking choline acetyltransferase. Neuron 36:635-648.
    • (2002) Neuron , vol.36 , pp. 635-648
    • Misgeld, T.1    Burgess, R.W.2    Lewis, R.M.3    Cunningham, J.M.4    Lichtman, J.W.5
  • 48
    • 0037439758 scopus 로고    scopus 로고
    • Aberrant patterning of neuromuscular synapses in choline acetyltransferase-deficient mice
    • Brandon EP, Lin W, D'Amour KA, Pizzo DP, Dominguez B, et al. 2003. Aberrant patterning of neuromuscular synapses in choline acetyltransferase- deficient mice. J Neurosci 23:539-549.
    • (2003) J Neurosci , vol.23 , pp. 539-549
    • Brandon, E.P.1    Lin, W.2    D'Amour, K.A.3    Pizzo, D.P.4    Dominguez, B.5
  • 49
    • 0029863697 scopus 로고    scopus 로고
    • Acetylcholinesterase accelerates assembly of amyloid-beta-peptides into Alzheimer's fibrils: Possible role of the peripheral site of the enzyme
    • Inestrosa NC, Alvarez A, Perez CA, Moreno RD, Vicente M, et al. 1996. Acetylcholinesterase accelerates assembly of amyloid-beta-peptides into Alzheimer's fibrils: possible role of the peripheral site of the enzyme. Neuron 16:881-891.
    • (1996) Neuron , vol.16 , pp. 881-891
    • Inestrosa, N.C.1    Alvarez, A.2    Perez, C.A.3    Moreno, R.D.4    Vicente, M.5
  • 50
    • 3342963982 scopus 로고    scopus 로고
    • Detecting hidden sequence propensity for amyloid fibril formation
    • Yoon S, Welsh WJ. 2004. Detecting hidden sequence propensity for amyloid fibril formation. Protein Sci 13:2149-2160.
    • (2004) Protein Sci , vol.13 , pp. 2149-2160
    • Yoon, S.1    Welsh, W.J.2
  • 51
    • 0037992406 scopus 로고    scopus 로고
    • Comparative genomics: Insecticide resistance in mosquito vectors
    • Weill M, Lutfalla G, Mogensen K, Chandre F, Berthomieu A, et al. 2003. Comparative genomics: insecticide resistance in mosquito vectors. Nature 423:136-137.
    • (2003) Nature , vol.423 , pp. 136-137
    • Weill, M.1    Lutfalla, G.2    Mogensen, K.3    Chandre, F.4    Berthomieu, A.5
  • 52
    • 0028242847 scopus 로고
    • Drosophila melanogaster acetylcholinesterase: Identification and expression of two mutations responsible for cold- and heat-sensitive phenotypes
    • Mutera A, Bride JM, Pralavorio M, Fournier D. 1994. Drosophila melanogaster acetylcholinesterase: identification and expression of two mutations responsible for cold- and heat-sensitive phenotypes. Mol Gen Genet 243:699-705.
    • (1994) Mol Gen Genet , vol.243 , pp. 699-705
    • Mutera, A.1    Bride, J.M.2    Pralavorio, M.3    Fournier, D.4
  • 53
    • 0026530707 scopus 로고
    • Minigene rescues acetylcholinesterase lethal mutations in Drosophila melanogaster
    • Hoffmann F, Fournier D, Spierer P. 1992. Minigene rescues acetylcholinesterase lethal mutations in Drosophila melanogaster. J Mol Biol 223:17-22.
    • (1992) J Mol Biol , vol.223 , pp. 17-22
    • Hoffmann, F.1    Fournier, D.2    Spierer, P.3
  • 54
    • 0029923812 scopus 로고    scopus 로고
    • Replacement of the glycoinositol phospholipid anchor of Drosophila acetylcholinesterase with a transmembrane domain does not alter sorting in neurons and epithelia but results in behavioral defects
    • Incardona JP, Rosenberry TL. 1996. Replacement of the glycoinositol phospholipid anchor of Drosophila acetylcholinesterase with a transmembrane domain does not alter sorting in neurons and epithelia but results in behavioral defects. Mol Biol Cell 7:613-630.
    • (1996) Mol Biol Cell , vol.7 , pp. 613-630
    • Incardona, J.P.1    Rosenberry, T.L.2
  • 55
    • 0032513228 scopus 로고    scopus 로고
    • Existence of four acetylcholinesterase genes in the nematodes Caenorhabditis elegans and Caenorhabditis briggsae
    • Grauso M, Culetto E, Combes D, Fedon Y, Toutant JP, et al. 1998. Existence of four acetylcholinesterase genes in the nematodes Caenorhabditis elegans and Caenorhabditis briggsae. FEBS Lett 424:279-284.
    • (1998) FEBS Lett , vol.424 , pp. 279-284
    • Grauso, M.1    Culetto, E.2    Combes, D.3    Fedon, Y.4    Toutant, J.P.5
  • 56
    • 0034697999 scopus 로고    scopus 로고
    • Four genes encode acetylcholinesterases in the nematodes Caenorhabditis elegans and Caenorhabditis briggsae. cDNA sequences, genomic structures, mutations and in vivo expression
    • Combes D, Fedon Y, Grauso M, Toutant JP, Arpagaus M. 2000. Four genes encode acetylcholinesterases in the nematodes Caenorhabditis elegans and Caenorhabditis briggsae. cDNA sequences, genomic structures, mutations and in vivo expression. J Mol Biol 300: 727-742.
    • (2000) J Mol Biol , vol.300 , pp. 727-742
    • Combes, D.1    Fedon, Y.2    Grauso, M.3    Toutant, J.P.4    Arpagaus, M.5
  • 57
    • 0021963370 scopus 로고
    • New acetylcholinesterase-deficient mutants of the nematode Caenorhabditis elegans
    • Kolson DL, Russell RL. 1985. New acetylcholinesterase-deficient mutants of the nematode Caenorhabditis elegans. J Neurogenet 2:69-91.
    • (1985) J Neurogenet , vol.2 , pp. 69-91
    • Kolson, D.L.1    Russell, R.L.2
  • 58
    • 0041879942 scopus 로고    scopus 로고
    • Multiple ace genes encoding acetylcholinesterases of Caenorhabditis elegans have distinct tissue expression
    • Combes D, Fedon Y, Toutant JP, Arpagaus M. 2003. Multiple ace genes encoding acetylcholinesterases of Caenorhabditis elegans have distinct tissue expression. Eur J Neurosci 18:497-512.
    • (2003) Eur J Neurosci , vol.18 , pp. 497-512
    • Combes, D.1    Fedon, Y.2    Toutant, J.P.3    Arpagaus, M.4
  • 59
    • 0024669454 scopus 로고
    • Genetic analysis of the cha-1-unc-17 gene complex in Caenorhabditis
    • Rand JB. 1989. Genetic analysis of the cha-1-unc-17 gene complex in Caenorhabditis. Genetics 122:73-80.
    • (1989) Genetics , vol.122 , pp. 73-80
    • Rand, J.B.1
  • 60
    • 14344253744 scopus 로고
    • Mutations in cha-1 and unc-17 suppress the ace-lethal phenotype
    • Rand J, Johnson C. 1986. Mutations in cha-1 and unc-17 suppress the ace-lethal phenotype. Worm Breeder's Gazette 9:115.
    • (1986) Worm Breeder's Gazette , vol.9 , pp. 115
    • Rand, J.1    Johnson, C.2
  • 61
    • 14344259284 scopus 로고
    • Nematode Acetylcholinesterase: Diversity and functions
    • Massoulié J, Bacou F, Barnard E, Chatonnet A, Doctor BP, Quinn DM, editor. London: Oxford University Press
    • Johnson CD. 1991. Nematode Acetylcholinesterase: Diversity and functions. In: Massoulié J, Bacou F, Barnard E, Chatonnet A, Doctor BP, Quinn DM, editor. Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology. London: Oxford University Press.
    • (1991) Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology
    • Johnson, C.D.1
  • 63
    • 0031768122 scopus 로고    scopus 로고
    • Time course of the development of motor behaviors in the zebrafish embryo
    • Saint-Amant L, Drapeau P. 1998. Time course of the development of motor behaviors in the zebrafish embryo. J Neurobiol 37:622-632.
    • (1998) J Neurobiol , vol.37 , pp. 622-632
    • Saint-Amant, L.1    Drapeau, P.2
  • 64
    • 0025310659 scopus 로고
    • Pathfinding and synapse formation in a zebrafish mutant lacking functional acetylcholine receptors
    • Westerfield M, Liu DW, Kimmel CB, Walker C. 1990. Pathfinding and synapse formation in a zebrafish mutant lacking functional acetylcholine receptors. Neuron 4:867-874.
    • (1990) Neuron , vol.4 , pp. 867-874
    • Westerfield, M.1    Liu, D.W.2    Kimmel, C.B.3    Walker, C.4
  • 65
    • 12644302205 scopus 로고    scopus 로고
    • Genes controlling and mediating locomotion behavior of the zebrafish embryo and larva
    • Granato M, van Eeden FJ, Schach U, Trowe T, Brand M, et al. 1996. Genes controlling and mediating locomotion behavior of the zebrafish embryo and larva. Development 123:399-413.
    • (1996) Development , vol.123 , pp. 399-413
    • Granato, M.1    Van Eeden, F.J.2    Schach, U.3    Trowe, T.4    Brand, M.5
  • 66
    • 2342662682 scopus 로고    scopus 로고
    • The use of zebrafish mutants to identify secondary target effects of acetylcholine esterase inhibitors
    • Behra M, Etard C, Cousin X, Strahle U. 2003. The use of zebrafish mutants to identify secondary target effects of acetylcholine esterase inhibitors. Toxicol Sci 2:2.
    • (2003) Toxicol Sci , vol.2 , pp. 2
    • Behra, M.1    Etard, C.2    Cousin, X.3    Strahle, U.4
  • 67
    • 0018731409 scopus 로고
    • Agonist-induced myopathy at the neuromuscular junction is mediated by calcium
    • Leonard JP, Salpeter MM. 1979. Agonist-induced myopathy at the neuromuscular junction is mediated by calcium. J Cell Biol 82:811-819.
    • (1979) J Cell Biol , vol.82 , pp. 811-819
    • Leonard, J.P.1    Salpeter, M.M.2
  • 68
    • 0033524439 scopus 로고    scopus 로고
    • Eserine and other tertiary amine interactions with Torpedo acetylcholine receptor post-synaptic membrane vesicles
    • Kawai H, Carlson BJ, Okita DK, Raftery MA. 1999. Eserine and other tertiary amine interactions with Torpedo acetylcholine receptor post-synaptic membrane vesicles. Biochemistry 38:134-141.
    • (1999) Biochemistry , vol.38 , pp. 134-141
    • Kawai, H.1    Carlson, B.J.2    Okita, D.K.3    Raftery, M.A.4
  • 69
    • 3042653108 scopus 로고    scopus 로고
    • Increased neuromuscular activity causes axonal defects and muscular degeneration
    • Lefebvre JL, Ono F, Puglielli C, Seidner G, Franzini-Armstrong C, et al. 2004. Increased neuromuscular activity causes axonal defects and muscular degeneration. Development 131:2605-2618.
    • (2004) Development , vol.131 , pp. 2605-2618
    • Lefebvre, J.L.1    Ono, F.2    Puglielli, C.3    Seidner, G.4    Franzini-Armstrong, C.5
  • 70
    • 0028944389 scopus 로고
    • A mutated acetylcholine receptor subunit causes neuronal degeneration in C. elegans
    • Treinin M, Chalfie M. 1995. A mutated acetylcholine receptor subunit causes neuronal degeneration in C. elegans. Neuron 14:871-877.
    • (1995) Neuron , vol.14 , pp. 871-877
    • Treinin, M.1    Chalfie, M.2
  • 71
    • 0033983498 scopus 로고    scopus 로고
    • Aberrant development of motor axons and neuromuscular synapses in erbB2-deficient mice
    • Lin W, Sanchez HB, Deerinck T, Morris JK, Ellisman M, et al. 2000. Aberrant development of motor axons and neuromuscular synapses in erbB2-deficient mice. Proc Natl Acad Sci USA 97:1299-1304.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 1299-1304
    • Lin, W.1    Sanchez, H.B.2    Deerinck, T.3    Morris, J.K.4    Ellisman, M.5
  • 73
    • 0032533934 scopus 로고    scopus 로고
    • Zebrafish touch-insensitive mutants reveal an essential role for the developmental regulation of sodium current
    • Ribera AB, Nusslein-Volhard C. 1998. Zebrafish touch-insensitive mutants reveal an essential role for the developmental regulation of sodium current. J Neurosci 18:9181-9191.
    • (1998) J Neurosci , vol.18 , pp. 9181-9191
    • Ribera, A.B.1    Nusslein-Volhard, C.2
  • 74
    • 0037114958 scopus 로고    scopus 로고
    • Nicotinic receptors mediate changes in spinal motoneuron development and axonal pathfinding in embryonic zebrafish exposed to nicotine
    • Svoboda KR, Vijayaraghavan S, Tanguay RL. 2002. Nicotinic receptors mediate changes in spinal motoneuron development and axonal pathfinding in embryonic zebrafish exposed to nicotine. J Neurosci 22:10731-10741.
    • (2002) J Neurosci , vol.22 , pp. 10731-10741
    • Svoboda, K.R.1    Vijayaraghavan, S.2    Tanguay, R.L.3
  • 75
    • 0032105405 scopus 로고    scopus 로고
    • The hypothesis of an ambient level of acetylcholine in the central nervous system
    • Descarries L. 1998. The hypothesis of an ambient level of acetylcholine in the central nervous system. J Physiol Paris 92:215-220.
    • (1998) J Physiol Paris , vol.92 , pp. 215-220
    • Descarries, L.1
  • 76
    • 0024352019 scopus 로고
    • Comparison of butyrylcholinesterase and acetylcholinesterase
    • Chatonnet A, Lockridge O. 1989. Comparison of butyrylcholinesterase and acetylcholinesterase. Biochem J 260:625-634.
    • (1989) Biochem J , vol.260 , pp. 625-634
    • Chatonnet, A.1    Lockridge, O.2
  • 77
    • 0027517144 scopus 로고
    • Three distinct domains in the cholinesterase molecule confer selectivity for acetyl- And butyrylcholinesterase inhibitors
    • Radie Z, Pickering NA, Vellom DC, Camp S, Taylor P. 1993. Three distinct domains in the cholinesterase molecule confer selectivity for acetyl- and butyrylcholinesterase inhibitors. Biochemistry 32:12074-12084.
    • (1993) Biochemistry , vol.32 , pp. 12074-12084
    • Radie, Z.1    Pickering, N.A.2    Vellom, D.C.3    Camp, S.4    Taylor, P.5
  • 79
    • 0027481817 scopus 로고
    • Degradation of acetylcholine in human airways: Role of butyrylcholinesterase
    • Norel X, Angrisani M, Labat C, Gorenne I, Dulmet E, et al. 1993. Degradation of acetylcholine in human airways: role of butyrylcholinesterase. Br J Pharmacol 108:914-919.
    • (1993) Br J Pharmacol , vol.108 , pp. 914-919
    • Norel, X.1    Angrisani, M.2    Labat, C.3    Gorenne, I.4    Dulmet, E.5
  • 80
    • 0025354508 scopus 로고
    • Role of butyrylcholinesterase in canine tracheal smooth muscle function
    • Adler M, Filbert MG. 1990. Role of butyrylcholinesterase in canine tracheal smooth muscle function. FEBS Lett 267:107-110.
    • (1990) FEBS Lett , vol.267 , pp. 107-110
    • Adler, M.1    Filbert, M.G.2
  • 81
    • 0032527453 scopus 로고    scopus 로고
    • Cholinesterases in cardiac ganglia and modulation of canine intrinsic cardiac neuronal activity
    • Darvesh S, MacDonald SE, Losier AM, Martin E, Hopkins DA, et al. 1998. Cholinesterases in cardiac ganglia and modulation of canine intrinsic cardiac neuronal activity. J Auton Nerv Syst 71:75-84.
    • (1998) J Auton Nerv Syst , vol.71 , pp. 75-84
    • Darvesh, S.1    MacDonald, S.E.2    Losier, A.M.3    Martin, E.4    Hopkins, D.A.5
  • 82
    • 0037375876 scopus 로고    scopus 로고
    • Cholinesterases: New roles in brain function and in Alzheimer's disease
    • Giacobini E. 2003. Cholinesterases: new roles in brain function and in Alzheimer's disease. Neurochem Res 28:515-522.
    • (2003) Neurochem Res , vol.28 , pp. 515-522
    • Giacobini, E.1
  • 83
    • 0023794322 scopus 로고
    • Acetylcholinesterase and butyrylcholinesterase in the gut mucosal cells of various mammal species: Distribution along the intestine and molecular forms
    • Sine JP, Ferrand R, Colas B. 1988. Acetylcholinesterase and butyrylcholinesterase in the gut mucosal cells of various mammal species: distribution along the intestine and molecular forms. Comp Biochem Physiol C 91:597-602.
    • (1988) Comp Biochem Physiol C , vol.91 , pp. 597-602
    • Sine, J.P.1    Ferrand, R.2    Colas, B.3
  • 85
    • 0037199344 scopus 로고    scopus 로고
    • Rescue of the acetylcholinesterase knockout mouse by feeding a liquid diet: Phenotype of the adult acetylcholinesterase deficient mouse
    • Duysen EG, Stribley JA, Fry DL, Hinrichs SH, Lockridge O. Rescue of the acetylcholinesterase knockout mouse by feeding a liquid diet: phenotype of the adult acetylcholinesterase deficient mouse. Brain Res Dev Brain Res 137:43-54.
    • Brain Res Dev Brain Res , vol.137 , pp. 43-54
    • Duysen, E.G.1    Stribley, J.A.2    Fry, D.L.3    Hinrichs, S.H.4    Lockridge, O.5
  • 86
    • 0034760772 scopus 로고    scopus 로고
    • Evidence for nonacetylcholinesterase targets of organophosphorus nerve agent: Supersensitivity of acetylcholinesterase knockout mouse to VX lethality
    • Duysen EG, Li B, Xie W, Schopfer LM, Anderson RS, et al. 2001. Lockridge O. Evidence for nonacetylcholinesterase targets of organophosphorus nerve agent: supersensitivity of acetylcholinesterase knockout mouse to VX lethality. J Pharmacol Exp Ther 299:528-535.
    • (2001) J Pharmacol Exp Ther , vol.299 , pp. 528-535
    • Duysen, E.G.1    Li, B.2    Xie, W.3    Schopfer, L.M.4    Anderson, R.S.5    Lockridge, O.6
  • 87
    • 0141619383 scopus 로고    scopus 로고
    • Respiratory survival mechanisms in acetylcholinesterase knockout mouse
    • Chatonnet F, Boudinot E, Chatonnet A, Taysse L, Daulon S, et al. 2003. Respiratory survival mechanisms in acetylcholinesterase knockout mouse. Eur J Neurosci 18:1419-1427.
    • (2003) Eur J Neurosci , vol.18 , pp. 1419-1427
    • Chatonnet, F.1    Boudinot, E.2    Chatonnet, A.3    Taysse, L.4    Daulon, S.5
  • 90
    • 12244284582 scopus 로고    scopus 로고
    • Butyrylcholinesterase and acetylcholinesterase activity and quantal transmitter release at normal and acetylcholinesterase knockout mouse neuromuscular junctions
    • Minic J, Chatonnet A, Krejci E, Molgo J. 2003. Butyrylcholinesterase and acetylcholinesterase activity and quantal transmitter release at normal and acetylcholinesterase knockout mouse neuromuscular junctions. Br J Pharmacol 138:177-187.
    • (2003) Br J Pharmacol , vol.138 , pp. 177-187
    • Minic, J.1    Chatonnet, A.2    Krejci, E.3    Molgo, J.4
  • 91
    • 0036456306 scopus 로고    scopus 로고
    • Regulation of acetylcholine release by muscarinic receptors at the mouse neuromuscular junction depends on the activity of acetylcholinesterase
    • Minic J, Molgo J, Karlsson E, Krejci E. 2002. Regulation of acetylcholine release by muscarinic receptors at the mouse neuromuscular junction depends on the activity of acetylcholinesterase. Eur J Neurosci 15:439-448.
    • (2002) Eur J Neurosci , vol.15 , pp. 439-448
    • Minic, J.1    Molgo, J.2    Karlsson, E.3    Krejci, E.4
  • 92
    • 0033594106 scopus 로고    scopus 로고
    • Genetic analysis of collagen Q: Roles in acetylcholinesterase and butyrylcholinesterase assembly and in synaptic structure and function
    • Feng G, Krejci E, Molgo J, Cunningham JM, Massoulié J, Sanes JR. 1999. Genetic analysis of collagen Q: roles in acetylcholinesterase and butyrylcholinesterase assembly and in synaptic structure and function. J Cell Biol 144:1349-1360.
    • (1999) J Cell Biol , vol.144 , pp. 1349-1360
    • Feng, G.1    Krejci, E.2    Molgo, J.3    Cunningham, J.M.4    Massoulié, J.5    Sanes, J.R.6
  • 93
    • 0345735775 scopus 로고    scopus 로고
    • Altered striatal function and muscarinic cholinergic receptors in acetylcholinesterase knockout mice
    • Volpicelli-Daley LA, Hrabovska A, Duysen EG, Ferguson SM, Blakely RD, et al. 2003. Altered striatal function and muscarinic cholinergic receptors in acetylcholinesterase knockout mice. Mol Pharmacol 64:1309-1316.
    • (2003) Mol Pharmacol , vol.64 , pp. 1309-1316
    • Volpicelli-Daley, L.A.1    Hrabovska, A.2    Duysen, E.G.3    Ferguson, S.M.4    Blakely, R.D.5
  • 94
    • 0038103811 scopus 로고    scopus 로고
    • Altered hippocampal muscarinic receptors in acetylcholinesterase- deficient mice
    • Volpicelli-Daley LA, Duysen EG, Lockridge O, Levey AI. 2003. Altered hippocampal muscarinic receptors in acetylcholinesterase-deficient mice. Ann Neural 53:788-796.
    • (2003) Ann Neural , vol.53 , pp. 788-796
    • Volpicelli-Daley, L.A.1    Duysen, E.G.2    Lockridge, O.3    Levey, A.I.4
  • 95
    • 0038512097 scopus 로고    scopus 로고
    • Dramatic depletion of cell surface m2 muscarinic receptor due to limited delivery from intracytoplasmic stores in neurons of acetylcholinesterase- deficient mice
    • Bernard V, Brana C, Liste I, Lockridge O, Bloch B. 2003. Dramatic depletion of cell surface m2 muscarinic receptor due to limited delivery from intracytoplasmic stores in neurons of acetylcholinesterase-deficient mice. Mol Cell Neurosci 23:121-133.
    • (2003) Mol Cell Neurosci , vol.23 , pp. 121-133
    • Bernard, V.1    Brana, C.2    Liste, I.3    Lockridge, O.4    Bloch, B.5
  • 97
    • 0030954673 scopus 로고    scopus 로고
    • The mammalian gene of acetylcholinesterase-associated collagen
    • Krejci E, Thomine S, Boschetti N, Legay C, Sketelj J, et al. 1997. The mammalian gene of acetylcholinesterase-associated collagen. J Biol Chem 272:22840-22847.
    • (1997) J Biol Chem , vol.272 , pp. 22840-22847
    • Krejci, E.1    Thomine, S.2    Boschetti, N.3    Legay, C.4    Sketelj, J.5
  • 98
    • 0037122918 scopus 로고    scopus 로고
    • PRiMA: The membrane anchor of acetylcholinesterase in the brain
    • Perrier AL, Massoulie J, Krejci E. 2002. PRiMA: the membrane anchor of acetylcholinesterase in the brain. Neuron 33:275-285.
    • (2002) Neuron , vol.33 , pp. 275-285
    • Perrier, A.L.1    Massoulie, J.2    Krejci, E.3
  • 100
    • 0028870647 scopus 로고
    • Characterization of a null mutation in ace-1, the gene encoding class a acetylcholinesterase in the nematode Caenorhabditis elegans
    • Talesa V, Culetto E, Schirru N, Bernardi H, Fedon Y, et al. 1995. Characterization of a null mutation in ace-1, the gene encoding class A acetylcholinesterase in the nematode Caenorhabditis elegans. FEBS Lett 357:265-268.
    • (1995) FEBS Lett , vol.357 , pp. 265-268
    • Talesa, V.1    Culetto, E.2    Schirru, N.3    Bernardi, H.4    Fedon, Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.