Single-molecule observations of topotecan-mediated TopIB activity at a unique DNA sequence

Nucleic Acids Research

Volumn 36, Issue 7, 2008, Pages 2301-2310

  Koster, Daniel A ^a,f   Czerwinski, Fabian ^a,c   Halby, Ludovic ^d,e   Crut, Aurélien ^a   Vekhoff, Pierre ^d,e   Palle, Komaraiah ^b   Arimondo, Paola B ^d,e   Dekker, Nynke H ^a  

^a DELFT UNIVERSITY OF TECHNOLOGY   (Netherlands)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d MUSÉUM NATIONAL D'HISTOIRE NATURELLE   (France)

^e INSERM   (France)

^f WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

CAMPTOTHECIN DERIVATIVE; DNA TOPOISOMERASE; OLIGONUCLEOTIDE; TOPOTECAN; ANTINEOPLASTIC AGENT; DNA; DRUG DERIVATIVE; ENZYME INHIBITOR; TOPOISOMERASE IB, HUMAN; TRIPLEX DNA;

ARTICLE; COMPLEX FORMATION; COVALENT BOND; DNA SEQUENCE; DNA SUPERCOILING; DRUG DNA BINDING; DRUG PROTEIN BINDING; ENZYME ACTIVITY; MAGNET; PRIORITY JOURNAL; SEQUENCE ANALYSIS; TRIPLE HELIX; BIOMECHANICS; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; NUCLEOTIDE SEQUENCE; SYNTHESIS;

ANTINEOPLASTIC AGENTS; BASE SEQUENCE; BIOMECHANICS; DNA; DNA TOPOISOMERASES, TYPE I, EUKARYOTIC; DNA, SUPERHELICAL; ENZYME INHIBITORS; TOPOTECAN;

EID: 42449159316     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkn035     Document Type: Article

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