Bone marrow stromal cells and the upregulation of interleukin-8 production in human T-cell acute lymphoblastic leukemia through the CXCL12/CXCR4 axis and the NF-κB and JNK/AP-1 pathways

Haematologica

Volumn 93, Issue 4, 2008, Pages 524-532

  Scupoli, Maria Teresa ^a,c   Donadelli, Massimo ^a   Cioffi, Federica ^a   Rossi, Maria ^a   Perbellini, Omar ^a   Malpeli, Giorgio ^a   Corbioli, Silvia ^a   Vinante, Fabrizio ^a   Krampera, Mauro ^a   Palmieri, Marta ^a   Scarpa, Aldo ^a   Ariola, Cristina ^b   Foà, Robin ^b   Pizzolo, Giovanni ^a  

^a UNIVERSITY OF VERONA   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c Laboratorio Universitario di Ricerca Medica (LURM)   (Italy)

Author keywords

Acute lymphoid leukemias; Chemokines; Tumor microenvironment

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; STROMAL CELL DERIVED FACTOR 1;

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; BONE MARROW CELL; CELL STIMULATION; CLINICAL TRIAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; ENZYME ACTIVITY; FLOW CYTOMETRY; GEL MOBILITY SHIFT ASSAY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MULTICENTER STUDY; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; STROMA CELL; T CELL LEUKEMIA; UPREGULATION;

ADULT; BONE MARROW CELLS; CHEMOKINE CXCL12; CLINICAL TRIALS AS TOPIC; GENE EXPRESSION REGULATION, LEUKEMIC; HUMANS; INTERLEUKIN-8; JNK MITOGEN-ACTIVATED PROTEIN KINASES; JURKAT CELLS; LEUKEMIA-LYMPHOMA, ADULT T-CELL; MULTICENTER STUDIES AS TOPIC; NEOPLASM PROTEINS; NF-KAPPA B; RECEPTORS, CXCR4; RECOMBINANT FUSION PROTEINS; RNA, MESSENGER; RNA, NEOPLASM; STROMAL CELLS; TRANSCRIPTION FACTOR AP-1; TRANSFECTION; UP-REGULATION;

EID: 42149181188     PISSN: 03906078     EISSN: None     Source Type: Journal    
DOI: 10.3324/haematol.12098     Document Type: Article

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