Liver mitochondrial properties from the obesity-resistant Lou/C rat

International Journal of Obesity

Volumn 32, Issue 4, 2008, Pages 629-638

  Lacraz, G ^a   Couturier, K ^a   Taleux, N ^a   Servais, S ^b   Sibille, B ^b   Letexier, D ^b   Guigas, B ^a   Dubouchaud, H ^a   Leverve, X ^a   Favier, R ^a  

^a INSERM   (France)

^b UNIVERSITÉ LYON 1   (France)

Author keywords

Cytochrome oxidase; Free radicals; High fat diet; Intrinsic uncoupling; Mitochondrial membrane potential; Oxidative phosphorylation efficiency

Indexed keywords

CARNITINE DERIVATIVE; CYTOCHROME; CYTOCHROME C OXIDASE; GLUTAMIC ACID; HYDROGEN PEROXIDE; MALIC ACID; MEDIUM CHAIN ACYL COENZYME A DEHYDROGENASE; OCTANOYL CARNITINE; SUCCINIC ACID; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 2;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BREATHING RATE; CALORIC INTAKE; CARBOHYDRATE DIET; CONTROLLED STUDY; DIET; ELECTRON TRANSPORT; ENZYME ACTIVITY; FAT INTAKE; LIVER MITOCHONDRION; LOW FAT DIET; MALE; MEMBRANE POTENTIAL; NONHUMAN; NUCLEOTIDE SEQUENCE; OBESITY; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RESPIRATORY CHAIN;

ANIMALS; DIETARY FATS; DISEASE SUSCEPTIBILITY; EATING; ENERGY INTAKE; GROWTH; HYDROGEN PEROXIDE; ION CHANNELS; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA, LIVER; MITOCHONDRIAL PROTEINS; OBESITY; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; RATS; RATS, INBRED STRAINS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SPECIES SPECIFICITY;

ANIMALIA; RATTUS; RATTUS NORVEGICUS;

EID: 42149164247     PISSN: 03070565     EISSN: 14765497     Source Type: Journal    
DOI: 10.1038/sj.ijo.0803779     Document Type: Article

References (47)

1. Couturier K, Servais S, Koubi H, Sempore B, Sornay-Mayet MH, Cottet-Emard JM et al. Metabolic characteristics and body composition in a model of anti-obese rats (Lou/C). Obes Res 2002; 10: 188-195.
2. Helies JM, Diane A, Langlois A, Larue-Achagiotis C, Fromentin G, Tomé D et al. Comparison of fat storage between Fischer 344 and obesity-resistant Lou/C rats fed different diets. Obes Res 2005; 13: 3-10.
3. Kappeler L, Zizzari P, Grouselle D, Epelbaum J, Bluet-Pajot MT. Plasma and hypothalamic peptide-hormone levels regulating somatotroph function and energy balance in fed and fasted states: a comparative study in four strains of rats. J Neuroendocrinol 2004; 16: 980-988.
4. Perrin D, Soulage C, Pequignot JM, Geloen A. Resistance to obesity in Lou/C rats prevents ageing-associated metabolic alterations. Diabetologia 2003; 46: 1489-1496.
5. Abdoulaye D, Wetzler S, Goubern M, Helies JM, Fromentin G, Tomé D et al. Comparison of energy balance in two inbred strains of rats: Fischer F344 prone to obesity and Lou rats resistant to obesity. Physiol Behav 2006; 87: 245-250.
6. Newby FD, DiGirolamo M, Cotsonis GA, Kutner MH. Model of spontaneous obesity in aging male Wistar rats. Am J Physiol 1990; 259: R1117-R1125.
7. Alliot J, Boghossian S, Jourdan D, Veyrat-Durebex C, Pickering G, Menial-Denis D et al. The LOU/c/jall rat as an animal model of healthy aging? J Gerontol A Biol Sci Med Sci 2002; 57: B312-B320.
8. Veyrat-Durebex C, Alliot J. Changes in pattern of macronutrient intake during aging in male and female rats. Physiol Behav 1997; 62: 1273-1278.
9. Kappeler L, Zizzari P, Alliot J, Epelbaum J, Bluet-Pajot MT. Delayed age-associated decrease in growth hormone pulsatile secretion and increased orexigenic peptide expression in the Lou C/JaLL rat. Neuroendocrinology 2004; 80: 273-283.
10. Merry BJ. Calorie restriction and age-related oxidative stress. Ann NY Acad Sci 2000; 908: 180-198.
11. Sohal RS, Weindruch R. Oxidative stress, caloric restriction, and aging. Science 1996; 273: 59-63.
12. Yu BP. Aging and oxidative stress: modulation by dietary restriction. Free Radic Biol Med 1996; 21: 651-668.
13. Frisard M, Ravussin E. Energy metabolism and oxidative stress: impact on the metabolic syndrome and the aging process. Endocrine 2006; 29: 27-32.
14. Couturier K, Servais S, Koubi H, Sempore B, Cottet-Emard JM, Guigas B et al. Metabolic and hormonal responses to exercise in the anti-obese Lou/C rats. Int J Obes Relat Metab Disord 2004; 28: 972-978.
15. Garait B, Couturier K, Servais S, Letexier D, Perrin D, Batandier C et al. Fat intake reverses the beneficial effects of low caloric intake on skeletal muscle mitochondrial H(2)O(2) production. Free Radic Biol Med 2005; 39: 1249-1261.
16. 2 generation in isolated mitochondria. J Bioenerg Biomembr 2002; 34: 227-233.
17. Nogueira V, Rigoulet M, Piquet MA, Devin A, Fontaine E, Leverve XM. Mitochondrial respiratory chain adjustment to cellular energy demand. J Biol Chem 2001; 276: 46104-46110.
18. Kamo N, Muratsugu M, Hongoh R, Kobatake Y. Membrane potential of mitochondria measured with an electrode sensitive to tetraphenyl phosphonium and relationship between proton electrochemical potential and phosphorylation potential in steady state. J Membr Biol 1979; 49: 105-121.
19. Williams Jr JN. A method for the simultaneous quantitative estimation of cytochromes A, B, C1, and C in mitochondria. Arch Biochem Biophys 1964; 107: 537-543.
20. Verity MA, Turnbull DM. Assay of acyl-CoA dehydrogenase activity in frozen muscle biopsies: application to medium-chain acyl-CoA dehydrogenase deficiency. Biochem Med Metab Biol 1993; 49: 351-362.
21. Alves-Guerra MC, Rousset S, Pecqueur C, Mallat Z, Blanc J, Tedgui A et al. Bone marrow transplantation reveals the in vivo expression of the mitochondrial uncoupling protein 2 in immune and nonimmune cells during inflammation. J Biol Chem 2003; 278: 42307-42312.
22. Brand MD, Chien LF, Diolez P. Experimental discrimination between proton leak and redox slip during mitochondrial electron transport. Biochem J 1994; 297 (Pt 1): 27-29.
23. Hurtaud C, Gelly C, Bouillaud F, Levi-Meyrueis C. Translation control of UCP2 synthesis by the upstream open reading frame. Cell Mol Life Sci 2006; 63: 1780-1789.
24. - stoichiometry in mitochondrial cytochrome c oxidase: influence of the rate of electron flow and transmembrane delta pH. Biochemistry 1996; 35: 10800-10806.
25. 2 production and oxidative DNA damage in rat liver mitochondria and location of the free radical source. J Bioenerg Biomembr 2001; 33: 279-287.
26. Hagopian K, Harper ME, Ram JJ, Humble SJ, Weindruch R, Ramsey JJ. Long-term calorie restriction reduces proton leak and hydrogen peroxide production in liver mitochondria. Am J Physiol Endocrinol Metab 2005; 288: E674-E684.
27. Lambert AJ, Merry BJ. Lack of effect of caloric restriction on bioenergetics and reactive oxygen species production in intact rat hepatocytes. J Gerontol A Biol Sci Med Sci 2005; 60: 175-180.
28. Lopez-Torres M, Gredilla R, Sanz A, Barja G. Influence of aging and long-term caloric restriction on oxygen radical generation and oxidative DNA damage in rat liver mitochondria. Free Radic Biol Med 2002; 32: 882-889.
29. Ramsey JJ, Hagopian K, Kenny TM, Koomson EK, Bevilacqua L, Weindruch R et al. Proton leak and hydrogen peroxide production in liver mitochondria from energy-restricted rats. Am J Physiol Endocrinol Metab 2004; 286: E31-E40.
30. Young TA, Cunningham CC, Bailey SM. Reactive oxygen species production by the mitochondrial respiratory chain in isolated rat hepatocytes and liver mitochondria: studies using myxothiazol. Arch Biochem Biophys 2002; 405: 65-72.
31. St-Pierre J, Buckingham JA, Roebuck SJ, Brand MD. Topology of superoxide production from different sites in the mitochondrial electron transport chain. J Biol Chem 2002; 277: 44784-44790.
32. Boveris A, Chance B. The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen. Biochem J 1973; 134: 707-716.
33. McGilvery R. Biochemistry: a Functional Approach. W.B. Saunders Company: Philadelphia, 1983, 909pp.
34. Wei Yuren WD, Topczewksi F, Pagliassotti Michael J. Saturated fatty acids induce endoplasmic reticulum stress and apoptosis independently of ceramide in liver cells. Am J Physiol 2006; 291: E275-E281.
35. Lambert AJ, Merry BJ. Effect of caloric restriction on mitochondrial reactive oxygen species production and bioenergetics: reversal by insulin. Am J Physiol Regul Integr Comp Physiol 2004; 286: R71-R79.
36. Vanhove G, Van Veldhoven PP, Eyssen HJ, Mannaerts GP. Mitochondrial short-chain acyl-CoA dehydrogenase of human liver and kidney can function as an oxidase. Biochem J 1993; 292 (Pt 1): 23-30.
37. Korshunov SS, Skulachev VP, Starkov AA. High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria. FEBS Lett 1997; 416: 15-18.
38. Papa S, Guerrieri F, Capitanio N. A possible role of slips in cytochrome C oxidase in the antioxygen defense system of the cell. Biosci Rep 1997; 17: 23-31.
39. Liu Y, Fiskum G, Schubert D. Generation of reactive oxygen species by the mitochondrial electron transport chain. J Neurochem 2002; 80: 780-787.
40. Kadenbach B. Intrinsic and extrinsic uncoupling of oxidative phosphorylation. Biochim Biophys Acta 2003; 1604: 77-94.
41. Larrouy D, Laharrague P, Carrera G, Viguerie-Bascands N, Levi-Meyrueis C, Fleury C et al. Kupffer cells are a dominant site of uncoupling protein 2 expression in rat liver. Biochem Biophys Res Commun 1997; 235: 760-764.
42. Nakatani T, Tsuboyama-Kasaoka N, Takahashi M, Miura S, Ezaki O. Mechanism for peroxisome proliferator-activated receptor-alpha activator-induced up-regulation of UCP2 mRNA in rodent hepatocytes. J Biol Chem 2002; 277: 9562-9569.
43. Wang Z, Pei H, Kaeck M, Lu J. Mammary cancer promotion and MAPK activation associated with consumption of a corn oil-based high-fat diet. Nutr Cancer 1999; 34: 140-146.
44. Slim RM, Toborek M, Watkins BA, Boissonneault GA, Hennig B. Susceptibility to hepatic oxidative stress in rabbits fed different animal and plant fats. J Am Coll Nutr 1996; 15: 289-294.
45. Kritchevsky D. Colorectal cancer: the role of dietary fat and caloric restriction. Mutat Res 1993; 290: 63-70.
46. Ishigaki Y, Katagiri H, Yamada T, Ogihara T, Imai J, Uno K et al. Dissipating excess energy stored in the liver is a potential treatment strategy for diabetes associated with obesity. Diabetes 2005; 54: 322-332.
47. Lee CF, Liu CY, Hsieh RH, Wei YH. Oxidative stress-induced depolymerization of microtubules and alteration of mitochondrial mass in human cells. Ann NY Acad Sci 2005; 1042: 246-254.