Protection from fatal viral encephalomyelitis: AMPA receptor antagonists have a direct effect on the inflammatory response to infection

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 9, 2008, Pages 3575-3580

  Greene, Ivorlyne P ^a   Lee, Eun Young ^a,b   Prow, Natalie ^a,c   Ngwang, Brownhilda ^a,d   Griffin, Diane E ^a  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^b Chungbuk National University College of Medicine   (South Korea)

^c UNIVERSITY OF QUEENSLAND   (Australia)

^d NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

Alphavirus; Glutamate; Paralysis; Sindbis virus; Talampanel

Indexed keywords

AMPA RECEPTOR ANTAGONIST; GLIAL FIBRILLARY ACIDIC PROTEIN; TALAMPANEL; AMPA RECEPTOR; BENZODIAZEPINE DERIVATIVE; GYKI 53405; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN INFECTION; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; ENCEPHALOMYELITIS; FEMALE; IMMUNITY; INFLAMMATION; MOUSE; NONHUMAN; PARALYSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SINDBIS VIRUS; T LYMPHOCYTE ACTIVATION; VIRUS ENCEPHALITIS; VIRUS REPLICATION; ANIMAL; BRAIN; C57BL MOUSE; DRUG ANTAGONISM; PATHOLOGY; VIROLOGY; VIRUS INFECTION;

ALPHAVIRUS; MUS; SINDBIS VIRUS;

ALPHAVIRUS INFECTIONS; ANIMALS; BENZODIAZEPINES; BRAIN; ENCEPHALOMYELITIS; FEMALE; INFLAMMATION; MICE; MICE, INBRED C57BL; RECEPTORS, AMPA; SINDBIS VIRUS; VIRUS DISEASES;

EID: 42149143477     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0712390105     Document Type: Article

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