CXCL10-induced cell death in neurons: Role of calcium dysregulation

European Journal of Neuroscience

Volumn 23, Issue 4, 2006, Pages 957-964

  Sui, Yongjun ^a   Stehno Bittel, Lisa ^a   Li, Shanping ^a   Loganathan, Rajprasad ^a   Dhillon, Navneet K ^a   Pinson, David ^a   Nath, Avindra ^b   Kolson, Dennis ^c   Narayan, Opendra ^a   Buch, Shilpa ^a  

^a UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Caspases; Chemokine; CXCL10; HIV associated dementia; Human; Neuronal apoptosis

Indexed keywords

CALCIUM; CASPASE; CASPASE 3; CASPASE 9; CHEMOKINE RECEPTOR CXCR3; CYTOCHROME C; GAMMA INTERFERON INDUCIBLE PROTEIN 10;

APOPTOSIS; ARTICLE; BRAIN MITOCHONDRION; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL MEMBRANE PERMEABILITY; ENZYME ACTIVATION; ENZYME RELEASE; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; NERVE CELL; NERVE CELL CULTURE; NERVE CELL NECROSIS; NEUROLOGIC DISEASE; PRIORITY JOURNAL; RECEPTOR BINDING; TEMPORAL CORTEX; UPREGULATION;

ANILINE COMPOUNDS; BLOTTING, WESTERN; BRAIN; CALCIUM; CASPASE 3; CASPASES; CELL COUNT; CELL DEATH; CELLS, CULTURED; CHEMOKINES, CXC; CYTOSOL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; ENZYME INHIBITORS; FETUS; GENE EXPRESSION; HUMANS; IMMUNOHISTOCHEMISTRY; MITOCHONDRIA; MODELS, NEUROLOGICAL; NEURONS; TERATOCARCINOMA; THAPSIGARGIN; XANTHENES;

EID: 33644781577     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2006.04631.x     Document Type: Article

References (49)

1. Asensio VC. Campbell IL. 1999 Chemokines in the CNS: plurifunctional mediators in diverse states Trends Neurosci 22 504 512
2. Asensio VC. Maier J. Milner R. Boztug K. Kincaid C. Moulard M. Phillipson C. Lindsley K. Krucker T. Fox HS. Campbell IL. 2001 Interferon-independent, human immunodeficiency virus type 1 gp120-mediated induction of CXCL10/IP-10 gene expression by astrocytes in vivo and in vitro JVirol 75 7067 7077
3. Bajetto A. Bonavia R. Barbero S. Schettini G. 2002 Characterization of chemokines and their receptors in the central nervous system: physiopathological implications JNeurochem 82 1311 1329
4. Clark-Lewis I. Mattioli I. Gong JH. Loetscher P. 2003 Structure-function relationship between the human chemokine receptor CXCR3 and its ligands JBiolChem 278 289 295
5. Coughlan CM. McManus CM. Sharron M. Gao Z. Murphy D. Jaffer S. Choe W. Chen W. Hesselgesser J. Gaylord H. Kalyuzhny A. Lee VM. Wolf B. Doms RW. Kolson DL. 2000 Expression of multiple functional chemokine receptors and monocyte chemoattractant protein-1 in human neurons Neuroscience 97 591 600
6. 2+ release by direct and specific action at skeletal muscle ryanodine receptors JBiolChem 272 26965 26971
7. Green DR. 1998 Apoptotic pathways: the roads to ruin Cell 94 695 698
8. Green DR. Reed JC. 1998 Mitochondria and apoptosis Science 281 1309 1312
9. Hartley RS. Margulis M. Fishman PS. Lee VM. Tang CM. 1999 Functional synapses are formed between human NTera2 (NT2N, hNT) neurons grown on astrocytes JCompNeurol 407 1 10
10. Hartmann A. Hunot S. Michel PP. Muriel MP. Vyas S. Faucheux BA. Mouatt-Prigent A. Turmel H. Srinivasan A. Ruberg M. Evan GI. Agid Y. Hirsch EC. 2000 Caspase-3: a vulnerability factor and final effector in apoptotic death of dopaminergic neurons in Parkinson's disease ProcNatl AcadSciUSA 97 2875 2880
11. Huang D. Han Y. Rani MR. Glabinski A. Trebst C. Sorensen T. Tani M. Wang J. Chien P. O'Bryan S. Bielecki B. Zhou ZL. Majumder S. Ransohoff RM. 2000 Chemokines and chemokine receptors in inflammation of the nervous system: manifold roles and exquisite regulation ImmunolRev 177 52 67
12. 2+ mobilizing mechanisms in cultured rat cerebellar granule cells JPhysiol 456 667 680
13. Kaul M. Garden GA. Lipton SA. 2001 Pathways to neuronal injury and apoptosis in HIV-associated dementia Nature 410 988 994
14. Kluck RM. Bossy-Wetzel E. Green DR. Newmeyer DD. 1997 The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis Science 275 1132 1136
15. Kolb SA. Sporer B. Lahrtz F. Koedel U. Pfister HW. Fontana A. 1999 Identification of a T cell chemotactic factor in the cerebrospinal fluid of HIV-1-infected individuals as interferon-gamma inducible protein 10 JNeuroimmunol 93 172 181
16. Kroemer G. 1999 Mitochondrial control of apoptosis: an overview BiochemSocSymp 66 1 15
17. Kutsch O. Oh J. Nath A. Benveniste EN. 2000 Induction of the chemokines interleukin-8 and IP-10 by human immunodeficiency virus type 1 tat in astrocytes JVirol 74 9214 9221
18. Lahrtz F. Piali L. Nadal D. Pfister HW. Spanaus KS. Baggiolini M. Fontana A. 1997 Chemotactic activity on mononuclear cells in the cerebrospinal fluid of patients with viral meningitis is mediated by interferon-gamma inducible protein-10 and monocyte chemotactic protein-1 EurJImmunol 27 2484 2489
19. Lasagni L. Francalanci M. Annunziato F. Lazzeri E. Giannini S. Cosmi L. Sagrinati C. Mazzinghi B. Orlando C. Maggi E. Marra F. Romagnani S. Serio M. Romagnani P. 2003 An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4 JExpMed 197 1537 1549
20. Llanes C. Collman RG. Hrin R. Kolson DL. 1995 Acetylcholinesterase expression in NTera 2 human neuronal cells: a model for developmental expression in the nervous system JNeurosciRes 42 791 802
21. Luster AD. Ravetch JV. 1987 Biochemical characterization of a gamma interferon-inducible cytokine (IP-10) JExp Med 166 1084 1097
22. Luster AD. Unkeless JC. Ravetch JV. 1985 Gamma-interferon transcriptionally regulates an early-response gene containing homology to platelet proteins Nature 315 672 676
23. van Marle G. Henry S. Todoruk T. Sullivan A. Silva C. Rourke SB. Holden J. McArthur JC. Gill MJ. Power C. 2004 Human immunodeficiency virus type 1 Nef protein mediates neural cell death: a neurotoxic role for IP-10 Virology 329 302 318
24. Matsuoka T. Kondoh T. Tamaki N. Nishizaki T. 1997 The GABAA receptor is expressed in human neurons derived from a teratocarcinoma cell line BiochemBiophysResCommun 237 719 723
25. Medina I. Filippova N. Bakhramov A. Bregestovski P. 1996 Calcium-induced inactivation of NMDA receptor-channels evolves independently of run-down in cultured rat brain neurones JPhysiol 495 411 427
26. 2+ in hippocampal neurons JNeurophysiol 72 456 465
27. 2+]i and the toxic actions of the HIV coat protein GP120 EurJNeurosci 11 1167 1178
28. Mennicken F. Maki R. de Souza EB. Quirion R. 1999 Chemokines and chemokine receptors in the CNS: a possible role in neuroinflammation and patterning Trends PharmacolSci 20 73 78
29. Munir M. Lu L. McGonigle P. 1995 Excitotoxic cell death and delayed rescue in human neurons derived from NT2 cells JNeurosci 15 7847 7860
30. Nelson TE. Gruol DL. 2004 The chemokine CXCL10 modulates excitatory activity and intracellular calcium signaling in cultured hippocampal neurons JNeuroimmunol 156 74 87
31. Newmeyer DD. Farschon DM. Reed JC. 1994 Cell-free apoptosis in Xenopus egg extracts: inhibition by Bcl-2 and requirement for an organelle fraction enriched in mitochondria Cell 79 353 364
32. Pleasure SJ. Page C. Lee VM. 1992 Pure, postmitotic, polarized human neurons derived from NTera 2 cells provide a system for expressing exogenous proteins in terminally differentiated neurons JNeurosci 12 1802 1815
33. Price DD. Mao J. Frenk H. Mayer DJ. 1994 The N-methyl-D-aspartate receptor antagonist dextromethorphan selectively reduces temporal summation of second pain in man Pain 59 165 174
34. Rootwelt T. Dunn M. Yudkoff M. Itoh T. Almaas R. Pleasure D. 1998 Hypoxic cell death in human NT2-N neurons: involvement of NMDA and non-NMDA glutamate receptors JNeurochem 71 1544 1553
35. Sanders VJ. Pittman CA. White MG. Wang G. Wiley CA. Achim CL. 1998 Chemokines and receptors in HIV encephalitis AIDS 12 1021 1026
36. Sasseville VG. Smith MM. Mackay CR. Pauley DR. Mansfield KG. Ringler DJ. Lackner AA. 1996 Chemokine expression in simian immunodeficiency virus-induced AIDS encephalitis AmJPathol 149 1459 1467
37. Scorrano L. Ashiya M. Buttle K. Weiler S. Oakes SA. Mannella CA. Korsmeyer SJ. 2002 A distinct pathway remodels mitochondrial cristae and mobilizes cytochrome c during apoptosis DevCell 2 55 67
38. 2+: a control point for apoptosis Science 300 135 139
39. Simpson JE. Newcombe J. Cuzner ML. Woodroofe MN. 2000 Expression of the interferon-gamma-inducible chemokines IP-10 and Mig and their receptor, CXCR3, in multiple sclerosis lesions Neuropathol ApplNeurobiol 26 133 142
40. Sui Y. Potula R. Dhillon N. Pinson D. Li S. Nath A. Anderson C. Turchan J. Kolson D. Narayan O. Buch S. 2004 Neuronal apoptosis is mediated by CXCL10 overexpression in simian human immunodeficiency virus encephalitis AmJPathol 164 1557 1566
41. Sui Y. Potula R. Pinson D. Adany I. Li Z. Day J. Buch E. Segebrecht J. Villinger F. Liu Z. Huang M. Narayan O. Buch S. 2003 Microarray analysis of cytokine and chemokine genes in the brains of macaques with SHIV-encephalitis JMed 32 229 239
42. Tacconi S. Perri R. Balestrieri E. Grelli S. Bernardini S. Annichiarico R. Mastino A. Caltagirone C. Macchi B. 2004 Increased caspase activation in peripheral blood mononuclear cells of patients with Alzheimer's disease ExpNeurol 190 254 262
43. Turchan J. Anderson C. Hauser KF. Sun Q. Zhang J. Liu Y. Wise PM. Kruman I. Maragos W. Mattson MP. Booze R. Nath A. 2001 Estrogen protects against the synergistic toxicity by HIV proteins, methamphetamine and cocaine BMC Neurosci 2 3
44. Wertkin AM. Turner RS. Pleasure SJ. Golde TE. Younkin SG. Trojanowski JQ. Lee VM. 1993 Human neurons derived from a teratocarcinoma cell line express solely the 695-amino acid amyloid precursor protein and produce intracellular beta-amyloid or A4 peptides ProcNatlAcadSciUSA 90 9513 9517
45. Westmoreland SV. Rottman JB. Williams KC. Lackner AA. Sasseville VG. 1998 Chemokine receptor expression on resident and inflammatory cells in the brain of macaques with simian immunodeficiency virus encephalitis AmJPathol 152 659 665
46. Wolf BA. Wertkin AM. Jolly YC. Yasuda RP. Wolfe BB. Konrad RJ. Manning D. Ravi S. Williamson JR. Lee VM. 1995 Muscarinic regulation of Alzheimer's disease amyloid precursor protein secretion and amyloid beta-protein production in human neuronal NT2N cells JBiolChem 270 4916 4922
47. Xia MQ. Bacskai BJ. Knowles RB. Qin SX. Hyman BT. 2000 Expression of the chemokine receptor CXCR3 on neurons and the elevated expression of its ligand IP-10 in reactive astrocytes: in vitro ERK1/2 activation and role in Alzheimer's disease JNeuroimmunol 108 227 235
48. Yang J. Liu X. Bhalla K. Kim CN. Ibrado AM. Cai J. Peng TI. Jones DP. Wang X. 1997 Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked Science 275 1129 1132
49. Zou H. Henzel WJ. Liu X. Lutschg A. Wang X. 1997 Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3 Cell 90 405 413