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Volumn 128, Issue 5, 2008, Pages 1236-1247

Chemical genetic screening identifies tricyclic compounds that decrease cellular melanin content

Author keywords

[No Author keywords available]

Indexed keywords

AMITRIPTYLINE; AMOXAPINE; CHLORPROTHIXENE; CLOMIPRAMINE; CLOZAPINE; CYCLOBENZAPRINE; CYPROHEPTADINE; DESIPRAMINE; DIZOCILPINE; DOXEPIN; IMIPRAMINE; LOXAPINE SUCCINATE; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MAPROTILINE; MELANIN; MONOPHENOL MONOOXYGENASE; NORTRIPTYLINE; ORPHENADRINE; PROMAZINE; PROTRIPTYLINE; THIAZINAMIUM; TRICYCLIC ANTIDEPRESSANT AGENT; TRIMIPRAMINE MALEATE; TRIPELENNAMINE;

EID: 42149089346     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/sj.jid.5701163     Document Type: Article
Times cited : (8)

References (69)
  • 1
    • 0018940271 scopus 로고
    • Acute effects of two melanocytolytic agents, hydroquinone and beta-mercaptoethanolamine, upon tyrosinase activity and cyclic nucleotide levels in murine melanomas
    • Abramowitz J, Chavin W (1980) Acute effects of two melanocytolytic agents, hydroquinone and beta-mercaptoethanolamine, upon tyrosinase activity and cyclic nucleotide levels in murine melanomas. Chem Biol Interact 32:195-208
    • (1980) Chem Biol Interact , vol.32 , pp. 195-208
    • Abramowitz, J.1    Chavin, W.2
  • 2
    • 0034697167 scopus 로고    scopus 로고
    • A common temperature-sensitive allelic form of human tyrosinase is retained in the endoplasmic reticulum at the nonpermissive temperature
    • Berson JF, Frank DW, Calvo PA, Bieler BM, Marks MS (2000) A common temperature-sensitive allelic form of human tyrosinase is retained in the endoplasmic reticulum at the nonpermissive temperature. J Biol Chem 275:12281-9
    • (2000) J Biol Chem , vol.275 , pp. 12281-12289
    • Berson, J.F.1    Frank, D.W.2    Calvo, P.A.3    Bieler, B.M.4    Marks, M.S.5
  • 3
    • 0031716330 scopus 로고    scopus 로고
    • Altered protein localization in melanocytes from Hermansky-Pudlak syndrome: Support for the role of the HPS gene product in intracellular trafficking
    • Boissy RE, Zhao Y, Gahl WA (1998) Altered protein localization in melanocytes from Hermansky-Pudlak syndrome: support for the role of the HPS gene product in intracellular trafficking. Lab Invest 78:1037-48
    • (1998) Lab Invest , vol.78 , pp. 1037-1048
    • Boissy, R.E.1    Zhao, Y.2    Gahl, W.A.3
  • 4
    • 0038580778 scopus 로고    scopus 로고
    • Chemical and instrumental approaches to treat hyperpigmentation
    • Briganti S, Camera E, Picardo M (2003) Chemical and instrumental approaches to treat hyperpigmentation. Pigment Cell Res 16:101-10
    • (2003) Pigment Cell Res , vol.16 , pp. 101-110
    • Briganti, S.1    Camera, E.2    Picardo, M.3
  • 5
    • 0037428468 scopus 로고    scopus 로고
    • Antidepressant-induced switch of beta 1-adrenoceptor trafficking as a mechanism for drug action
    • Bürgi S, Baltensperger K, Honegger UE (2003) Antidepressant-induced switch of beta 1-adrenoceptor trafficking as a mechanism for drug action. J Biol Chem 278:1044-52
    • (2003) J Biol Chem , vol.278 , pp. 1044-1052
    • Bürgi, S.1    Baltensperger, K.2    Honegger, U.E.3
  • 6
    • 0035985173 scopus 로고    scopus 로고
    • Pink-eyed dilution protein controls the processing of tyrosinase
    • Chen K, Manga P, Orlow SJ (2002) Pink-eyed dilution protein controls the processing of tyrosinase. Mol Biol Cell 13:1953-64
    • (2002) Mol Biol Cell , vol.13 , pp. 1953-1964
    • Chen, K.1    Manga, P.2    Orlow, S.J.3
  • 7
    • 0041885144 scopus 로고    scopus 로고
    • Tyrosinase processing and intracellular trafficking is disrupted in mouse primary melanocytes carrying the underwhite (uw) mutation. A model for oculocutaneous albinism (OCA) type 4
    • Costin G-E, Valencia JC, Vieira WD, Lynn Lamoreux M, Hearing VJ (2003) Tyrosinase processing and intracellular trafficking is disrupted in mouse primary melanocytes carrying the underwhite (uw) mutation. A model for oculocutaneous albinism (OCA) type 4. J Cell Sci 116:3203-12
    • (2003) J Cell Sci , vol.116 , pp. 3203-3212
    • Costin, G.-E.1    Valencia, J.C.2    Vieira, W.D.3    Lynn Lamoreux, M.4    Hearing, V.J.5
  • 8
    • 42149119736 scopus 로고    scopus 로고
    • Cullen MK (1998) Genetic epidermal syndromes: disorders characterized by lentigines. In: The pigmentary system: physiology and pathophysiology. (James J. Nordlund, Raymond E. Boissy, Vincent J. Hearing, Richard A. King, Jean-Paul Ortonne, eds), New York: Oxford University Press, 760-6
    • Cullen MK (1998) Genetic epidermal syndromes: disorders characterized by lentigines. In: The pigmentary system: physiology and pathophysiology. (James J. Nordlund, Raymond E. Boissy, Vincent J. Hearing, Richard A. King, Jean-Paul Ortonne, eds), New York: Oxford University Press, 760-6
  • 9
    • 0033559796 scopus 로고    scopus 로고
    • Inhibitors of mammalian melanocyte tyrosinase: In vitro comparisons of alkyl esters of gentisic acid with other putative inhibitors
    • Curto EV, Kwong C, Hermersdorfer H (1999) Inhibitors of mammalian melanocyte tyrosinase: in vitro comparisons of alkyl esters of gentisic acid with other putative inhibitors. Biochem Pharmacol 15:663-72
    • (1999) Biochem Pharmacol , vol.15 , pp. 663-672
    • Curto, E.V.1    Kwong, C.2    Hermersdorfer, H.3
  • 10
    • 1542504222 scopus 로고    scopus 로고
    • Melanosome biogenesis: Shedding light on the origin of an obscure organelle
    • Dell'Angelica EC (2003) Melanosome biogenesis: shedding light on the origin of an obscure organelle. Trends Cell Bio 13:503-6
    • (2003) Trends Cell Bio , vol.13 , pp. 503-506
    • Dell'Angelica, E.C.1
  • 11
    • 0028926923 scopus 로고
    • Lysosomal hydrolases are present in melanosomes and are elevated in melanizing cells
    • Diment S, Eidelman M, Rodriguez GM, Orlow SJ (1995) Lysosomal hydrolases are present in melanosomes and are elevated in melanizing cells. J Biol Chem 270:4213-5
    • (1995) J Biol Chem , vol.270 , pp. 4213-4215
    • Diment, S.1    Eidelman, M.2    Rodriguez, G.M.3    Orlow, S.J.4
  • 13
    • 0028822323 scopus 로고
    • The antipruritic effect of 5% doxepin cream in patients with eczematous dermatitis. Doxepin study group
    • Drake LA, Millikan LE (1995) The antipruritic effect of 5% doxepin cream in patients with eczematous dermatitis. Doxepin study group. Arch Dermatol 131:1403-8
    • (1995) Arch Dermatol , vol.131 , pp. 1403-1408
    • Drake, L.A.1    Millikan, L.E.2
  • 15
    • 0037565706 scopus 로고    scopus 로고
    • Accumulation of tyrosinase in the endolysosomal compartment is induced by U18666A
    • Hall AM, Krishnamoorthy L, Orlow SJ (2003) Accumulation of tyrosinase in the endolysosomal compartment is induced by U18666A. Pigment Cell Res 16:149-58
    • (2003) Pigment Cell Res , vol.16 , pp. 149-158
    • Hall, A.M.1    Krishnamoorthy, L.2    Orlow, S.J.3
  • 16
    • 15944424673 scopus 로고    scopus 로고
    • Degradation of tyrosinase induced by phenylthiourea occurs following Golgi maturation
    • Hall AM, Orlow SJ (2005) Degradation of tyrosinase induced by phenylthiourea occurs following Golgi maturation. Pigment Cell Res 18:122-9
    • (2005) Pigment Cell Res , vol.18 , pp. 122-129
    • Hall, A.M.1    Orlow, S.J.2
  • 17
    • 0035989977 scopus 로고    scopus 로고
    • Redefining the skin's pigmentary system with a novel tyrosinase assay
    • Han R, Baden HP, Brissette JL, Weiner L (2002) Redefining the skin's pigmentary system with a novel tyrosinase assay. Pigment Cell Res 15:290-7
    • (2002) Pigment Cell Res , vol.15 , pp. 290-297
    • Han, R.1    Baden, H.P.2    Brissette, J.L.3    Weiner, L.4
  • 18
    • 0023068990 scopus 로고
    • Mammalian monophenol monooxygenase (tyrosinase): Purification, properties, and reactions catalyzed
    • Hearing VJ (1987) Mammalian monophenol monooxygenase (tyrosinase): purification, properties, and reactions catalyzed. Methods Enzymol 142:154-65
    • (1987) Methods Enzymol , vol.142 , pp. 154-165
    • Hearing, V.J.1
  • 19
    • 11144314304 scopus 로고    scopus 로고
    • Biogenesis of pigment granules: A sensitive way to regulate melanocyte function
    • Hearing VJ (2005) Biogenesis of pigment granules: a sensitive way to regulate melanocyte function. J Dermatol Sci 37:3-14
    • (2005) J Dermatol Sci , vol.37 , pp. 3-14
    • Hearing, V.J.1
  • 20
    • 0020596992 scopus 로고
    • Evidence for lysosomotropic action of desipramine in cultured human fibroblasts
    • Honegger UE, Roscher AA, Wiesmann UN (1983) Evidence for lysosomotropic action of desipramine in cultured human fibroblasts. J Pharmacol Exp Ther 225:436-41
    • (1983) J Pharmacol Exp Ther , vol.225 , pp. 436-441
    • Honegger, U.E.1    Roscher, A.A.2    Wiesmann, U.N.3
  • 21
    • 0028468309 scopus 로고
    • The tricyclic antidepressant desipramine causes proteolytic degradation of lysosomal sphingomyelinase in human fibroblasts
    • Hurwitz R, Ferlinz K, Sandhoff K (1994) The tricyclic antidepressant desipramine causes proteolytic degradation of lysosomal sphingomyelinase in human fibroblasts. Biol Chem Hoppe Seyler 375:447-50
    • (1994) Biol Chem Hoppe Seyler , vol.375 , pp. 447-450
    • Hurwitz, R.1    Ferlinz, K.2    Sandhoff, K.3
  • 23
    • 0025964036 scopus 로고
    • Tyrosinases from two different loci are expressed by normal and by transformed melanocytes
    • Jimenez M, Tsukamoto K, Hearing VJ (1991) Tyrosinases from two different loci are expressed by normal and by transformed melanocytes. J Biol Chem 266:1147-56
    • (1991) J Biol Chem , vol.266 , pp. 1147-1156
    • Jimenez, M.1    Tsukamoto, K.2    Hearing, V.J.3
  • 25
    • 26644443924 scopus 로고    scopus 로고
    • Identification of the F1F0 mitochondrial ATPase as a target for modulating skin pigmentation by screening a tagged triazine library in zebrafish
    • Jung DW, Williams D, Khersonsky SM, Kang TW, Heidary N, Chang YT et al. (2005) Identification of the F1F0 mitochondrial ATPase as a target for modulating skin pigmentation by screening a tagged triazine library in zebrafish. Mol Biosyst 1:85-92
    • (2005) Mol Biosyst , vol.1 , pp. 85-92
    • Jung, D.W.1    Williams, D.2    Khersonsky, S.M.3    Kang, T.W.4    Heidary, N.5    Chang, Y.T.6
  • 26
    • 4544334518 scopus 로고    scopus 로고
    • Strategies for facilitated forward chemical genetics
    • Khersonsky SM, Chang YT (2004) Strategies for facilitated forward chemical genetics. Chembiochem 5:903-8
    • (2004) Chembiochem , vol.5 , pp. 903-908
    • Khersonsky, S.M.1    Chang, Y.T.2
  • 27
    • 23844545621 scopus 로고    scopus 로고
    • Tyrosinase inhibitors from natural and synthetic sources: Structure, inhibition mechanism and perspective for the future
    • Kim Y-J, Uyama H (2005) Tyrosinase inhibitors from natural and synthetic sources: structure, inhibition mechanism and perspective for the future. Cell Mol Life Sci 62:1707-23
    • (2005) Cell Mol Life Sci , vol.62 , pp. 1707-1723
    • Kim, Y.-J.1    Uyama, H.2
  • 28
    • 0442323490 scopus 로고    scopus 로고
    • Interactions of acid sphingomyelinase and lipid bilayers in the presence of the tricyclic antidepressant desipramine
    • Kolzer M, Werth N, Sandhoff K (2004) Interactions of acid sphingomyelinase and lipid bilayers in the presence of the tricyclic antidepressant desipramine. FEBS Lett 559:96-8
    • (2004) FEBS Lett , vol.559 , pp. 96-98
    • Kolzer, M.1    Werth, N.2    Sandhoff, K.3
  • 29
    • 0019945365 scopus 로고
    • Mammalian tyrosinase catalyzes three reactions in the biosynthesis of melanin
    • Korner A, Pawelek J (1982) Mammalian tyrosinase catalyzes three reactions in the biosynthesis of melanin. Science 217:1163-5
    • (1982) Science , vol.217 , pp. 1163-1165
    • Korner, A.1    Pawelek, J.2
  • 30
    • 0035490904 scopus 로고    scopus 로고
    • The melanosome: Membrane dynamics in black and white
    • Marks MS, Seabra MC (2001) The melanosome: membrane dynamics in black and white. Nat Rev Mol Cell Biol 2:738-48
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 738-748
    • Marks, M.S.1    Seabra, M.C.2
  • 31
    • 0033625754 scopus 로고    scopus 로고
    • Topical application of doxepin hydrochloride, capsaicin and a combination of both produces analgesia in chronic human neuropathic pain: A randomized, double-blind, placebo-controlled study
    • McCleane G (2000) Topical application of doxepin hydrochloride, capsaicin and a combination of both produces analgesia in chronic human neuropathic pain: a randomized, double-blind, placebo-controlled study. Br J Clin Pharmacol 49:574-9
    • (2000) Br J Clin Pharmacol , vol.49 , pp. 574-579
    • McCleane, G.1
  • 32
    • 0023179999 scopus 로고
    • Inhibition of melanization in human melanoma cells by a serotonin uptake inhibitor
    • McEwan M, Parsons PG (1987) Inhibition of melanization in human melanoma cells by a serotonin uptake inhibitor. J Invest Dermatol 89:82-6
    • (1987) J Invest Dermatol , vol.89 , pp. 82-86
    • McEwan, M.1    Parsons, P.G.2
  • 33
    • 33749363368 scopus 로고    scopus 로고
    • Imipramine-induced facial pigmentation: Case report and literature review
    • Metelitsa AI, Nguyen GK, Lin AN (2005) Imipramine-induced facial pigmentation: case report and literature review. J Cutan Med Surg 9:341-5
    • (2005) J Cutan Med Surg , vol.9 , pp. 341-345
    • Metelitsa, A.I.1    Nguyen, G.K.2    Lin, A.N.3
  • 36
    • 31344481037 scopus 로고    scopus 로고
    • Heterologous expression of tyrosinase recapitulates the misprocessing and mistrafficking in oculocutaneous albinism type 2: Effects of altering intracellular pH and pink-eyed dilution gene expression
    • Ni-Komatsu L, Orlow SJ (2006) Heterologous expression of tyrosinase recapitulates the misprocessing and mistrafficking in oculocutaneous albinism type 2: effects of altering intracellular pH and pink-eyed dilution gene expression. Exp Eye Res 82:519-28
    • (2006) Exp Eye Res , vol.82 , pp. 519-528
    • Ni-Komatsu, L.1    Orlow, S.J.2
  • 37
    • 34250628806 scopus 로고    scopus 로고
    • Identification of novel pigmentation modulators by chemical genetic screening
    • Ni-Komatsu L, Orlow SJ (2007) Identification of novel pigmentation modulators by chemical genetic screening. J Invest Dermatol 127:1585-92
    • (2007) J Invest Dermatol , vol.127 , pp. 1585-1592
    • Ni-Komatsu, L.1    Orlow, S.J.2
  • 38
    • 0029081168 scopus 로고
    • Melanosomes are specialized members of the lysosomal lineage of organelles
    • Orlow SJ (1995) Melanosomes are specialized members of the lysosomal lineage of organelles. J Invest Dermatol 105:3-7
    • (1995) J Invest Dermatol , vol.105 , pp. 3-7
    • Orlow, S.J.1
  • 39
    • 0026717402 scopus 로고
    • Imipramine induced lipidosis and dexamethasone effect: Morphological and biochemical study in normal and chronic GM2 gangliosidosis fibroblasts
    • Palmeri S, Mangano L, Battisti C, Malandrini A, Federico A (1992) Imipramine induced lipidosis and dexamethasone effect: morphological and biochemical study in normal and chronic GM2 gangliosidosis fibroblasts. J Neurol Sci 110:215-21
    • (1992) J Neurol Sci , vol.110 , pp. 215-221
    • Palmeri, S.1    Mangano, L.2    Battisti, C.3    Malandrini, A.4    Federico, A.5
  • 41
    • 0021236568 scopus 로고
    • Depigmenting action of hydroquinone depends on disruption of fundamental cell processes
    • Penney KB, Smith CJ, Allen JC (1984) Depigmenting action of hydroquinone depends on disruption of fundamental cell processes. J Invest Dermatol 82:308-10
    • (1984) J Invest Dermatol , vol.82 , pp. 308-310
    • Penney, K.B.1    Smith, C.J.2    Allen, J.C.3
  • 43
    • 0036219181 scopus 로고    scopus 로고
    • The dark side of lysosome-related organelles: Specialization of the endocytic pathway for melanosome biogenesis
    • Raposo G, Marks MS (2002) The dark side of lysosome-related organelles: specialization of the endocytic pathway for melanosome biogenesis. Traffic 3:237-48
    • (2002) Traffic , vol.3 , pp. 237-248
    • Raposo, G.1    Marks, M.S.2
  • 44
    • 12944284535 scopus 로고    scopus 로고
    • Melanocytes derived from patients with Hermansky-Pudlak syndrome types 1, 2, and 3 have distinct defects in cargo trafficking
    • Richmond B, Huizing M, Knapp J, Koshoffer A, Zhao Y, Gahl WA et al. (2005) Melanocytes derived from patients with Hermansky-Pudlak syndrome types 1, 2, and 3 have distinct defects in cargo trafficking. J Invest Dermatol 124:420-7
    • (2005) J Invest Dermatol , vol.124 , pp. 420-427
    • Richmond, B.1    Huizing, M.2    Knapp, J.3    Koshoffer, A.4    Zhao, Y.5    Gahl, W.A.6
  • 45
    • 0026410676 scopus 로고
    • Type C Niemann-Pick disease: Use of hydrophobic amines to study defective cholesterol transport
    • Roff CF, Goldin E, Comly ME, Cooney A, Brown A, Vanier MT et al. (1991) Type C Niemann-Pick disease: use of hydrophobic amines to study defective cholesterol transport. Dev Neurosci 13:315-9
    • (1991) Dev Neurosci , vol.13 , pp. 315-319
    • Roff, C.F.1    Goldin, E.2    Comly, M.E.3    Cooney, A.4    Brown, A.5    Vanier, M.T.6
  • 46
    • 0031594702 scopus 로고    scopus 로고
    • Accumulation of cholesterol and GM2 ganglioside in cells cultured in the presence of progesterone: An implication for the basic defect in Niemann-Pick disease type C
    • Sato M, Akaboshi S, Katsumoto T, Taniguchi M, Higaki K, Tai T et al. (1998) Accumulation of cholesterol and GM2 ganglioside in cells cultured in the presence of progesterone: an implication for the basic defect in Niemann-Pick disease type C. Brain Dev 20:50-2
    • (1998) Brain Dev , vol.20 , pp. 50-52
    • Sato, M.1    Akaboshi, S.2    Katsumoto, T.3    Taniguchi, M.4    Higaki, K.5    Tai, T.6
  • 47
    • 0037416141 scopus 로고    scopus 로고
    • The small-molecule approach to biology
    • Schreiber SL (2003) The small-molecule approach to biology. Chem Eng News 81:51-61
    • (2003) Chem Eng News , vol.81 , pp. 51-61
    • Schreiber, S.L.1
  • 50
    • 0033017893 scopus 로고    scopus 로고
    • Photoinduced dermal pigmentation in patients taking tricyclic antidepressants: Histology, electron microscopy, and energy dispersive spectroscopy
    • Sicari MC, Lebwohl M, Baral J, Wexler P, Gordon RE, Phelps RG (1999) Photoinduced dermal pigmentation in patients taking tricyclic antidepressants: histology, electron microscopy, and energy dispersive spectroscopy. J Am Acad Dermatol 40:290-3
    • (1999) J Am Acad Dermatol , vol.40 , pp. 290-293
    • Sicari, M.C.1    Lebwohl, M.2    Baral, J.3    Wexler, P.4    Gordon, R.E.5    Phelps, R.G.6
  • 51
    • 4644237315 scopus 로고    scopus 로고
    • Melanin pigmentation in mammalian skin and its hormonal regulation
    • Slominski A, Tobin DJ, Shibahara S, Wortsman J (2004) Melanin pigmentation in mammalian skin and its hormonal regulation. Physiol Rev 84:1155-228
    • (2004) Physiol Rev , vol.84 , pp. 1155-1228
    • Slominski, A.1    Tobin, D.J.2    Shibahara, S.3    Wortsman, J.4
  • 52
    • 13244267262 scopus 로고    scopus 로고
    • The cutaneous serotoninergic/melatoninergic system: Securing a place under the sun
    • Slominski A, Wortsman J, Tobin DJ (2005) The cutaneous serotoninergic/melatoninergic system: securing a place under the sun. FASEB J 19:176-94
    • (2005) FASEB J , vol.19 , pp. 176-194
    • Slominski, A.1    Wortsman, J.2    Tobin, D.J.3
  • 55
    • 33750538670 scopus 로고    scopus 로고
    • Hypopigmentation agents: An updated review on biological, chemical and clinical aspects
    • Solano F, Briganti S, Picardo M, Ghanem G (2006) Hypopigmentation agents: an updated review on biological, chemical and clinical aspects. Pigment Cell Res 19:550-71
    • (2006) Pigment Cell Res , vol.19 , pp. 550-571
    • Solano, F.1    Briganti, S.2    Picardo, M.3    Ghanem, G.4
  • 57
    • 0035984725 scopus 로고    scopus 로고
    • Sweet surrender to chemical genetics
    • Tan DS (2002) Sweet surrender to chemical genetics. Nat Biotechnol 20:561-3
    • (2002) Nat Biotechnol , vol.20 , pp. 561-563
    • Tan, D.S.1
  • 58
    • 0025268565 scopus 로고
    • Single and multiple desipramine exposures of cultured cells. Changes in cellular anisotropy and in lipid composition of whole cells and of plasma membranes
    • Toplak H, Zuehlke R, Loidl S, Hermetter A, Honegger UE, Wiesmann UN (1990) Single and multiple desipramine exposures of cultured cells. Changes in cellular anisotropy and in lipid composition of whole cells and of plasma membranes. Biochem Pharmacol 39:1437-43
    • (1990) Biochem Pharmacol , vol.39 , pp. 1437-1443
    • Toplak, H.1    Zuehlke, R.2    Loidl, S.3    Hermetter, A.4    Honegger, U.E.5    Wiesmann, U.N.6
  • 59
    • 0036016306 scopus 로고    scopus 로고
    • The etiology of oculocutaneous albinism (OCA) type II: The pink protein modulates the processing and transport of tyrosinase
    • Toyofuku K, Valencia JC, Kushimoto T, Costin GE, Virador VM, Vieira WD et al. (2002) The etiology of oculocutaneous albinism (OCA) type II: the pink protein modulates the processing and transport of tyrosinase. Pigment Cell Res 15:217-24
    • (2002) Pigment Cell Res , vol.15 , pp. 217-224
    • Toyofuku, K.1    Valencia, J.C.2    Kushimoto, T.3    Costin, G.E.4    Virador, V.M.5    Vieira, W.D.6
  • 61
    • 0027056307 scopus 로고    scopus 로고
    • Tripathi RK, Hearing VJ, Urabe K, Aroca P, Spritz RA (1992) Mutational mapping of the catalytic activities of human tyrosinase. J Biol Chem 267:23707-12
    • Tripathi RK, Hearing VJ, Urabe K, Aroca P, Spritz RA (1992) Mutational mapping of the catalytic activities of human tyrosinase. J Biol Chem 267:23707-12
  • 62
    • 42149129024 scopus 로고    scopus 로고
    • Urabe K, Nakayama J, Hori Y (1998) Mixed epidermal and dermal hypermelanoses. In: The pigmentary system: physiology and pathophysiology. (James J. Nordlund, Raymond E. Boissy, Vincent J. Hearing, Richard A. King, Jean-Paul Ortonne, eds), New York: Oxford University Press, 909-11
    • Urabe K, Nakayama J, Hori Y (1998) Mixed epidermal and dermal hypermelanoses. In: The pigmentary system: physiology and pathophysiology. (James J. Nordlund, Raymond E. Boissy, Vincent J. Hearing, Richard A. King, Jean-Paul Ortonne, eds), New York: Oxford University Press, 909-11
  • 63
    • 33645057693 scopus 로고    scopus 로고
    • Hermansky-Pudlak syndrome: A disease of protein trafficking and organelle function
    • Wei ML (2006) Hermansky-Pudlak syndrome: a disease of protein trafficking and organelle function. Pigment Cell Res 19:19-42
    • (2006) Pigment Cell Res , vol.19 , pp. 19-42
    • Wei, M.L.1
  • 65
    • 0026354903 scopus 로고
    • Expression of a mouse tyrosinase cDNA in 3T3 Swiss mouse fibroblasts
    • Winder AJ (1991) Expression of a mouse tyrosinase cDNA in 3T3 Swiss mouse fibroblasts. Biochem Biophys Res Commun 178:739-45
    • (1991) Biochem Biophys Res Commun , vol.178 , pp. 739-745
    • Winder, A.J.1
  • 66
    • 0027418696 scopus 로고
    • Fibroblasts expressing mouse c locus tyrosinase produce an authentic enzyme and synthesize phaeomelanin
    • Winder AJ, Wittbjer A, Rosengren E, Rorsman H (1993a) Fibroblasts expressing mouse c locus tyrosinase produce an authentic enzyme and synthesize phaeomelanin. J Cell Sci 104:467-75
    • (1993) J Cell Sci , vol.104 , pp. 467-475
    • Winder, A.J.1    Wittbjer, A.2    Rosengren, E.3    Rorsman, H.4
  • 67
    • 0027378040 scopus 로고
    • The mouse brown (b) locus protein has dopachrome tautomerase activity and is located in lysosomes in transfected fibroblasts
    • Winder AJ, Wittbjer A, Rosengren E, Rorsman H (1993b) The mouse brown (b) locus protein has dopachrome tautomerase activity and is located in lysosomes in transfected fibroblasts. J Cell Sci 106:153-66
    • (1993) J Cell Sci , vol.106 , pp. 153-166
    • Winder, A.J.1    Wittbjer, A.2    Rosengren, E.3    Rorsman, H.4
  • 68
    • 0027936741 scopus 로고
    • On the analysis of the pathophysiology of Chediak-Higashi syndrome. Defects expressed by cultured melanocytes
    • Zhao H, Boissy YL, Abdel-Malek Z, King RA, Nordlund JJ, Boissy RE (1994) On the analysis of the pathophysiology of Chediak-Higashi syndrome. Defects expressed by cultured melanocytes. Lab Invest 71:25-34
    • (1994) Lab Invest , vol.71 , pp. 25-34
    • Zhao, H.1    Boissy, Y.L.2    Abdel-Malek, Z.3    King, R.A.4    Nordlund, J.J.5    Boissy, R.E.6
  • 69
    • 12144273121 scopus 로고    scopus 로고
    • In vivo drug discovery in the zebrafish
    • Zon LI, Peterson RT (2005) In vivo drug discovery in the zebrafish. Nat Rev Drug Discov 4:35-44
    • (2005) Nat Rev Drug Discov , vol.4 , pp. 35-44
    • Zon, L.I.1    Peterson, R.T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.