Dissection of melanogenesis with small molecules identifies prohibitin as a regulator

Chemistry and Biology

Volumn 12, Issue 4, 2005, Pages 477-484

  Snyder, Jane R ^a,b   Hall, Andrea ^a,b   Ni Komatsu, Li ^a,b   Khersonsky, Sonya M ^b   Chang, Young Tae ^b   Orlow, Seth J ^a,b  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NEW YORK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MAMMALIA;

EID: 17844362208     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2005.02.014     Document Type: Article

References (31)

1. D. Tan Sweet surrender to chemical genetics Nat. Biotechnol. 20 2002 561 562
2. S.L. Schreiber Target-oriented and diversity-oriented organic synthesis in drug discovery Science 287 2000 1964 1968
3. L. Burdine, and T. Kodadek Target identification in chemical genetics: the (often) missing link Chem. Biol. 11 2004 593 597
4. M. Knockaert, N. Gray, E. Damiens, Y.T. Chang, P. Grellier, K. Grant, D. Fergusson, J. Mottram, M. Soete, and J.F. Dubremetz Intracellular targets of cyclin-dependent kinase inhibitors: identification by affinity chromatography using immobilised inhibitors Chem. Biol. 7 2000 411 422
5. D.A. Brown Skin pigmentation enhancers J. Photochem. Photobiol. B 63 2001 148 161
6. F.G. Kuruvilla, A.F. Shamji, S.M. Sternson, P.J. Hergenrother, and S.L. Schreiber Dissecting glucose signaling with diversity-oriented synthesis and small-molecule microarrays Nature 416 2002 653 657
7. G.R. Rosania, Y.T. Chang, O. Perez, D. Sutherlin, H. Dong, D.J. Lockhart, and P.G. Schultz Myoseverin, a microtubule-binding molecule with novel cellular effects Nat. Biotechnol. 18 2000 304 308
8. T.U. Mayer, T.M. Kapoor, S.J. Haggarty, R.W. King, S.L. Schreiber, and T.J. Mitchison Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen Science 286 1999 971 974
9. Y. Zhao, X. Dai, H.E. Blackwell, S.L. Schreiber, and J. Chory SIR 1, an upstream component in auxin signaling identified by chemical genetics Science 301 2003 1107 1110
10. S.M. Khersonsky, D.W. Jung, T.W. Kang, D.P. Walsh, H.S. Moon, H. Jo, E.M. Jacobson, V. Shetty, T.A. Neubert, and Y.T. Chang Facilitated forward chemical genetics using a tagged triazine library and zebrafish embryo screening J. Am. Chem. Soc. 125 2003 11804 11805
11. D.C. Bennett, and P.J. Cooper A line of non-tumorigenic mouse melanocytes, syngenic with the B16 melanoma and requiring a tumor promoter for growth Int. J. Cancer 39 1987 414 418
12. D.C. Bennett, P.J. Cooper, T.J. Dexter, L.M. Devlin, J. Heasman, and B. Nester Cloned mouse melanocyte lines carrying the germline mutations albino and brown: complementation in culture Development 126 1989 379 385
13. S.J. Orlow, A.K. Chakraborty, R.E. Boissy, and J. Pawelek Inhibition of induced melanogenesis in Cloudman melanoma cells by four phenotypic modifiers Exp. Cell Res. 191 1990 209 218
14. S. Pomerantz The tyrosine hydroxylase activity of mammalian tyrosinase J. Biol. Chem. 241 1996 161 168
15. A. Hall, L. Krishnamoorthy, and S.J. Orlow Accumulation of tyrosinase in the endolysosomal compartment is induced by U18666A Pigment Cell Res. 16 2003 149 158
16. D.W.H. Scharn, U. Reineke, J. Schneider-Mergener, and L. Germeroth Spatially addressed synthesis of amino- and amino-oxy-substituted 1,3,5-triazine arrays on polymeric membranes J. Comb. Chem. 2 2000 361 369
17. 0 mitochondrial ATPase by screening a tagged triazine library for the correction of oculocutaneous albinism type 2 Chem. Biol. 11 2004 1251 1259
18. M.L.M. Stankova Library generation through successive substitution of trichlorotriazine Mol. Divers. 2 1996 75 80
19. C. Gaggioli, R. Busca, P. Abbe, J.P. Ortonne, and R. Ballotti Microphthalmia-associated transcription factor (MITF) is required but is not sufficient to induce the expression of melanogenic genes Pigment Cell Res. 16 2003 374 382
20. S. Bacher, G. Achatz, M.L. Schmitz, and M.C. Lamers Prohibitin and prohibitone are contained in high-molecular weight complexes and interact with alpha-actinin and annexin A2 Biochimie 84 2002 1207 1220
21. A.J. Darmon, and P.S. Jat BAP37 and prohibitin are specifically recognized by an SV40T antigen antibody Mol. Cell Biol. Res. Commun. 4 2000 219 223
22. G. Fusaro, P. Dasgupta, S. Rastogi, B. Joshi, and S. Chellappan Prohibitin induces the transcriptional activity of p53 and is exported from the nucleus upon apoptotic signaling J. Biol. Chem. 278 2003 47853 47861
23. L.G. Nijtmans, S.M. Artal, L.A. Grivell, and P.J. Coates The mitochondrial PHB complex: roles in mitochondrial respiratory complex assembly, ageing and degenerative disease Cell. Mol. Life Sci. 59 2002 143 155
24. P.J. Coates, R. Nenutil, A. McGregor, S.M. Picksley, D.H. Crouch, P.A. Hall, and E.G. Wright Mammalian prohibitin proteins respond to mitochondrial stress and decrease during cellular senescence Exp. Cell Res. 265 2001 262 273
25. J.K. McClung, E.R. Jupe, X.T. Liu, and R.T. Dell'Orco Prohibitin: potential role in senescence, development and tumor suppression Exp. Gerontol. 30 1995 99 124
26. S. Wang, N. Nath, M. Adlam, and S. Chellappan Prohibitin, a potential tumor suppressor, interacts with RB and regulates E2F function Oncogene 18 1999 3501 3510
27. S. Wang, B. Zhang, and D.V. Faller Prohibitin requires Brg-1 and Brm for the repression of E2F and cell growth EMBO J. 21 2002 3019 3028
28. A. Menssen, and H. Hermeking Characterization of the c-MYC-regulated transcriptome by SAGE: identification and analysis of c-MYC target genes Proc. Natl. Acad. Sci. USA 99 2002 6274 6279
29. S. Wang, N. Nath, G. Fusaro, and S. Chellappan Rb and prohibitin target distinct regions of E2F1 for repression and respond to different upstream signals Mol. Cell. Biol. 19 1999 7447 7460
30. L.G.J. Nijtmans, L. de Jong, M. Artal Sanz, P.J. Coates, J.A. Berden, J.W. Back, A.O. Muijsers, H. van der Spek, and L.A. Grivell Prohibitins act as a membrane-bound chaperone for the stabilization of mitochondrial proteins EMBO J. 19 2000 2444 2451
31. C.-M. Huang, K.W. Foster, T. DeSilva, J. Zhang, Z. Shi, N. Yusuf, K.R. Van Kampen, C.A. Elmets, and D.C. Tang Comparative proteomic profiling of murine skin J. Invest. Dermatol. 121 2003 51 64