Triazine-based tyrosinase inhibitors identified by chemical genetic screening

Pigment Cell Research

Volumn 18, Issue 6, 2005, Pages 447-453

  Ni Komatsu, Li ^a   Leung, Jennifer K ^a   Williams, Darren ^a   Min, Jaeki ^b   Khersonsky, Sonya M ^b   Chang, Young Tae ^b   Orlow, Seth J ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NEW YORK UNIVERSITY   (United States)

Author keywords

Chemical genetics; Melanocyte; Pigmentation inhibitors; Triazine based combinatorial library; Tyrosinase

Indexed keywords

DEPIGMENTING AGENT; DOPA; LEVODOPA; MELANIN; MONOPHENOL MONOOXYGENASE; OXYGENASE INHIBITOR; TGD 10; TGD 24; TGD 39; TGG 11; TGH 11; TGJ 24; TGJ 29; TRIAZINE DERIVATIVE; UNCLASSIFIED DRUG;

AFFINITY CHROMATOGRAPHY; ANIMAL CELL; ARTICLE; BINDING SITE; CELL CULTURE; CHEMICAL GENETICS; CONTROLLED STUDY; CYTOTOXICITY; DRUG BINDING; DRUG IDENTIFICATION; DRUG SCREENING; ENZYME KINETICS; GENETIC SCREENING; HYPERPIGMENTATION; IC 50; MELANOCYTE; MELANOGENESIS; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PROCESSING;

ANIMALS; ANTIGENS, NEOPLASM; BINDING SITES; BINDING, COMPETITIVE; CELLS, CULTURED; CHROMATOGRAPHY, AFFINITY; ENZYME INHIBITORS; GENETIC SCREENING; KINETICS; LEVODOPA; MELANINS; MELANOCYTES; MICE; MONOPHENOL MONOOXYGENASE; NEOPLASM PROTEINS; PIGMENTATION; PROTEIN TRANSPORT; TRIAZINES;

ANIMALIA;

EID: 28044463805     PISSN: 08935785     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0749.2005.00273.x     Document Type: Article

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