Tyrosinase processing and intracellular trafficking is disrupted in mouse primary melanocytes carrying the underwhite (uw) mutation. A model for oculocutaneous albinism (OCA) type 4

Journal of Cell Science

Volumn 116, Issue 15, 2003, Pages 3203-3212

  Costin, Gertrude E ^a   Valencia, Julio C ^b   Vieira, Wilfred D ^a   Lamoreux, M Lynn ^c   Hearing, Vincent J ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^c TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Albinism; OCA4; Pigmentation; Tyrosinase; Underwhite

Indexed keywords

CARRIER PROTEIN; DOPACHROME TAUTOMERASE; MONOPHENOL MONOOXYGENASE; TYROSINASE RELATED PROTEIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL MATURATION; CELL MUTANT; CELL ORGANELLE; CELL VACUOLE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; ENZYME RELEASE; ENZYME SYNTHESIS; GENE MUTATION; GENETIC CODE; GOLGI COMPLEX; HYPOPIGMENTATION; MELANOCYTE; MELANOSOME; MOUSE; NONHUMAN; OCULOCUTANEOUS ALBINISM; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PROCESSING; PROTEIN TARGETING; PROTEIN TRANSPORT; REGULATORY MECHANISM; WILD TYPE;

ALBINISM, OCULOCUTANEOUS; ANIMALS; ENZYME ACTIVATION; INTRAMOLECULAR OXIDOREDUCTASES; MELANOCYTES; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MONOPHENOL MONOOXYGENASE; OXIDOREDUCTASES; PROTEIN TRANSPORT; SECRETORY VESICLES; SKIN; SKIN PIGMENTATION;

ANIMALIA; MAMMALIA; OXALIS TUBEROSA; TRIXIS;

EID: 0041885144     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.00598     Document Type: Article

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