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Volumn 33, Issue 6, 2008, Pages 1276-1286

Dopamine depletion of the prefrontal cortex induces dendritic spine loss: Reversal by atypical antipsychotic drug treatment

Author keywords

Dendrite; Haloperidol; Motor cortex; Olanzapine; Pyramidal cell; Schizophrenia

Indexed keywords

DOPAMINE; HALOPERIDOL; OLANZAPINE; OXIDOPAMINE;

EID: 42049111635     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.npp.1301521     Document Type: Article
Times cited : (76)

References (94)
  • 1
    • 0032819210 scopus 로고    scopus 로고
    • Lamina-specific alterations in the dopamine innervation of the prefrontal cortex in schizophrenic subjects
    • Akil M, Pierri JN, Whitehead RE, Edgar CL, Mohila C, Sampson AR et al (1999). Lamina-specific alterations in the dopamine innervation of the prefrontal cortex in schizophrenic subjects. Am J Psychiatry 156: 1580-1589.
    • (1999) Am J Psychiatry , vol.156 , pp. 1580-1589
    • Akil, M.1    Pierri, J.N.2    Whitehead, R.E.3    Edgar, C.L.4    Mohila, C.5    Sampson, A.R.6
  • 2
    • 4344648827 scopus 로고    scopus 로고
    • The relationship between brain structure and neurocognition in schizophrenia: A selective review
    • Antonova E, Sharma T, Morris R, Kumari V (2004). The relationship between brain structure and neurocognition in schizophrenia: a selective review. Schizophr Res 70: 117-145.
    • (2004) Schizophr Res , vol.70 , pp. 117-145
    • Antonova, E.1    Sharma, T.2    Morris, R.3    Kumari, V.4
  • 3
    • 3142739323 scopus 로고    scopus 로고
    • Adrenergic targets for the treatment of cognitive deficits in schizophrenia
    • Arnsten AF (2004). Adrenergic targets for the treatment of cognitive deficits in schizophrenia. Psychopharmacology (Berl) 174: 25-31.
    • (2004) Psychopharmacology (Berl) , vol.174 , pp. 25-31
    • Arnsten, A.F.1
  • 4
    • 0032007608 scopus 로고    scopus 로고
    • Do novel antipsychotics have similar pharmacological characteristics? A review of the evidence
    • Arnt J, Skarsfeldt T (1998). Do novel antipsychotics have similar pharmacological characteristics? A review of the evidence. Neuropsychopharmacology 18: 63-101.
    • (1998) Neuropsychopharmacology , vol.18 , pp. 63-101
    • Arnt, J.1    Skarsfeldt, T.2
  • 5
    • 33845768335 scopus 로고    scopus 로고
    • The effects of morphine self-administration on cortical pyramidal cell structure in addiction-prone lewis rats
    • Ballesteros-Yanez I, Ambrosio E, Benavides-Piccione R, Perez J, Torres I, Miguens M et al (2007). The effects of morphine self-administration on cortical pyramidal cell structure in addiction-prone lewis rats. Cereb Cortex 17: 238-249.
    • (2007) Cereb Cortex , vol.17 , pp. 238-249
    • Ballesteros-Yanez, I.1    Ambrosio, E.2    Benavides-Piccione, R.3    Perez, J.4    Torres, I.5    Miguens, M.6
  • 6
    • 0035811508 scopus 로고    scopus 로고
    • Cortical remodelling induced by activity of ventral tegmental dopamine neurons
    • Bao S, Chan VT, Merzenich MM (2001). Cortical remodelling induced by activity of ventral tegmental dopamine neurons. Nature 412: 79-83.
    • (2001) Nature , vol.412 , pp. 79-83
    • Bao, S.1    Chan, V.T.2    Merzenich, M.M.3
  • 7
    • 0021988597 scopus 로고
    • The effects of haloperidol on synaptic patterns in the rat striatum
    • Benes FM, Paskevich PA, Davidson J, Domesick VB (1985). The effects of haloperidol on synaptic patterns in the rat striatum. Brain Res 329: 265-273.
    • (1985) Brain Res , vol.329 , pp. 265-273
    • Benes, F.M.1    Paskevich, P.A.2    Davidson, J.3    Domesick, V.B.4
  • 8
    • 0036268294 scopus 로고    scopus 로고
    • Neurocognitive effects of clozapine, olanzapine, risperidone, and haloperidol in patients with chronic schizophrenia or schizoaffective disorder
    • Bilder RM, Goldman RS, Volavka J, Czobor P, Hoptman M, Sheitman B et al (2002). Neurocognitive effects of clozapine, olanzapine, risperidone, and haloperidol in patients with chronic schizophrenia or schizoaffective disorder. Am J Psychiatry 159: 1018-1028.
    • (2002) Am J Psychiatry , vol.159 , pp. 1018-1028
    • Bilder, R.M.1    Goldman, R.S.2    Volavka, J.3    Czobor, P.4    Hoptman, M.5    Sheitman, B.6
  • 10
    • 2942560575 scopus 로고    scopus 로고
    • Microanatomy of dendritic spines: Emerging principles of synaptic pathology in psychiatric and neurological disease
    • Blanpied TA, Ehlers MD (2004). Microanatomy of dendritic spines: emerging principles of synaptic pathology in psychiatric and neurological disease. Biol Psychiatry 55: 1121-1127.
    • (2004) Biol Psychiatry , vol.55 , pp. 1121-1127
    • Blanpied, T.A.1    Ehlers, M.D.2
  • 11
    • 0036842250 scopus 로고    scopus 로고
    • Evidence for a decrease in basilar dendrites of pyramidal cells in schizophrenic medial prefrontal cortex
    • Broadbelt K, Byne W, Jones LB (2002). Evidence for a decrease in basilar dendrites of pyramidal cells in schizophrenic medial prefrontal cortex. Schizophr Res 58: 75-81.
    • (2002) Schizophr Res , vol.58 , pp. 75-81
    • Broadbelt, K.1    Byne, W.2    Jones, L.B.3
  • 12
    • 26844558556 scopus 로고    scopus 로고
    • Mild, short-term stress alters dendritic morphology in rat medial prefrontal cortex
    • Brown SM, Henning S, Wellman CL (2005). Mild, short-term stress alters dendritic morphology in rat medial prefrontal cortex. Cereb Cortex 15: 1714-1722.
    • (2005) Cereb Cortex , vol.15 , pp. 1714-1722
    • Brown, S.M.1    Henning, S.2    Wellman, C.L.3
  • 15
    • 15944369335 scopus 로고    scopus 로고
    • Spine architecture and synaptic plasticity
    • Carlisle HJ, Kennedy MB (2005). Spine architecture and synaptic plasticity. Trends Neurosci 28: 182-187.
    • (2005) Trends Neurosci , vol.28 , pp. 182-187
    • Carlisle, H.J.1    Kennedy, M.B.2
  • 17
    • 38749118384 scopus 로고    scopus 로고
    • Specific configuration of dendritic degeneration in pyramidal neurons of the medial prefrontal cortex induced by differing corticosteroid regimens
    • doi:10.1093/cercor/bhii08
    • Cerqueira JJ, Taipa R, Uylings HB, Almeida OF, Sousa N (2006). Specific configuration of dendritic degeneration in pyramidal neurons of the medial prefrontal cortex induced by differing corticosteroid regimens. Cereb Cortex (doi:10.1093/cercor/bhii08).
    • (2006) Cereb Cortex
    • Cerqueira, J.J.1    Taipa, R.2    Uylings, H.B.3    Almeida, O.F.4    Sousa, N.5
  • 18
    • 49049131252 scopus 로고
    • Do dendritic spines twitch?
    • Crick F (1982). Do dendritic spines twitch? Trends Neurosci 5: 44-46.
    • (1982) Trends Neurosci , vol.5 , pp. 44-46
    • Crick, F.1
  • 19
    • 8844286003 scopus 로고    scopus 로고
    • Prefrontal executive and cognitive functions in rodents: Neural and neurochemical substrates
    • Dalley JW, Cardinal RN, Robbins TW (2004). Prefrontal executive and cognitive functions in rodents: neural and neurochemical substrates. Neurosci Biobehav Rev 28: 771-784.
    • (2004) Neurosci Biobehav Rev , vol.28 , pp. 771-784
    • Dalley, J.W.1    Cardinal, R.N.2    Robbins, T.W.3
  • 20
    • 0026070134 scopus 로고
    • Dopamine in schizophrenia: A review and reconceptualization
    • Davis KL, Kahn RS, Ko G, Davidson M (1991). Dopamine in schizophrenia: a review and reconceptualization. Am J Psychiatry 148: 1474-1486.
    • (1991) Am J Psychiatry , vol.148 , pp. 1474-1486
    • Davis, K.L.1    Kahn, R.S.2    Ko, G.3    Davidson, M.4
  • 21
    • 0035477920 scopus 로고    scopus 로고
    • Olanzapine activates the rat locus coeruleus: In vivo electrophysiology and c-Fos immunoreactivity
    • Dawe GS, Huff KD, Vandergriff JL, Sharp T, O'Neill MJ, Rasmussen K (2001). Olanzapine activates the rat locus coeruleus: in vivo electrophysiology and c-Fos immunoreactivity. Biol Psychiatry 50: 510-520.
    • (2001) Biol Psychiatry , vol.50 , pp. 510-520
    • Dawe, G.S.1    Huff, K.D.2    Vandergriff, J.L.3    Sharp, T.4    O'Neill, M.J.5    Rasmussen, K.6
  • 22
    • 31544465246 scopus 로고    scopus 로고
    • Selective elimination of glutamatergic synapses on striatopallidal neurons in Parkinson disease models
    • Day M, Wang Z, Ding J, An X, Ingham CA, Shering AF et al (2006). Selective elimination of glutamatergic synapses on striatopallidal neurons in Parkinson disease models. Nat Neurosci 9: 251-259.
    • (2006) Nat Neurosci , vol.9 , pp. 251-259
    • Day, M.1    Wang, Z.2    Ding, J.3    An, X.4    Ingham, C.A.5    Shering, A.F.6
  • 23
    • 0026611392 scopus 로고
    • The regulation of subcortical dopamine systems by the prefrontal cortex: Interactions of central dopamine systems and the pathogenesis of schizophrenia
    • Deutch AY (1992). The regulation of subcortical dopamine systems by the prefrontal cortex: interactions of central dopamine systems and the pathogenesis of schizophrenia. J Neural Transm Suppl 36: 61-89.
    • (1992) J Neural Transm Suppl , vol.36 , pp. 61-89
    • Deutch, A.Y.1
  • 24
    • 0026567360 scopus 로고
    • Pharmacological characterization of dopamine systems in the nucleus accumbens core and shell
    • Deutch AY, Cameron DS (1992). Pharmacological characterization of dopamine systems in the nucleus accumbens core and shell. Neuroscience 46: 49-56.
    • (1992) Neuroscience , vol.46 , pp. 49-56
    • Deutch, A.Y.1    Cameron, D.S.2
  • 25
    • 0025286232 scopus 로고
    • Prefrontal cortical dopamine depletion enhances the responsiveness of mesolimbic dopamine neurons to stress
    • Deutch AY, Clark WA, Roth RH (1990). Prefrontal cortical dopamine depletion enhances the responsiveness of mesolimbic dopamine neurons to stress. Brain Res 521: 311-315.
    • (1990) Brain Res , vol.521 , pp. 311-315
    • Deutch, A.Y.1    Clark, W.A.2    Roth, R.H.3
  • 26
    • 0021981617 scopus 로고
    • Footshock and conditioned stress increase 3,4-dihydroxyphenylacetic acid (DOPAC) in the ventral tegmental area but not substantia nigra
    • Deutch AY, Tam SY, Roth RH (1985). Footshock and conditioned stress increase 3,4-dihydroxyphenylacetic acid (DOPAC) in the ventral tegmental area but not substantia nigra. Brain Res 333: 143-146.
    • (1985) Brain Res , vol.333 , pp. 143-146
    • Deutch, A.Y.1    Tam, S.Y.2    Roth, R.H.3
  • 27
    • 0038070364 scopus 로고    scopus 로고
    • Co-release of noradrenaline and dopamine from noradrenergic neurons in the cerebral cortex induced by clozapine, the prototype atypical antipsychotic
    • Devoto P, Flore G, Vacca G, Pira L, Arca A, Casu MA et al (2003). Co-release of noradrenaline and dopamine from noradrenergic neurons in the cerebral cortex induced by clozapine, the prototype atypical antipsychotic. Psychopharmacology (Berl) 167: 79-84.
    • (2003) Psychopharmacology (Berl) , vol.167 , pp. 79-84
    • Devoto, P.1    Flore, G.2    Vacca, G.3    Pira, L.4    Arca, A.5    Casu, M.A.6
  • 28
    • 0041357082 scopus 로고    scopus 로고
    • Age-related dendritic and spine changes in corticocortically projecting neurons in macaque monkeys
    • Duan H, Wearne SL, Rocher AB, Macedo A, Morrison JH, Hof PR (2003). Age-related dendritic and spine changes in corticocortically projecting neurons in macaque monkeys. Cereb Cortex 13: 950-961.
    • (2003) Cereb Cortex , vol.13 , pp. 950-961
    • Duan, H.1    Wearne, S.L.2    Rocher, A.B.3    Macedo, A.4    Morrison, J.H.5    Hof, P.R.6
  • 29
    • 0036082812 scopus 로고    scopus 로고
    • Dendritic spine pathology: Cause or consequence of neurological disorders?
    • Fiala JC, Spacek J, Harris KM (2002). Dendritic spine pathology: cause or consequence of neurological disorders? Brain Res Brain Res Rev 39: 29-54.
    • (2002) Brain Res Brain Res Rev , vol.39 , pp. 29-54
    • Fiala, J.C.1    Spacek, J.2    Harris, K.M.3
  • 30
    • 0021676562 scopus 로고
    • Tyrosine hydroxylase- immunoreactive boutons in synaptic contact with identified striatonigral neurons, with particular reference to dendritic spines
    • Freund TF, Powell JF, Smith AD (1984). Tyrosine hydroxylase- immunoreactive boutons in synaptic contact with identified striatonigral neurons, with particular reference to dendritic spines. Neuroscience 13: 1189-1215.
    • (1984) Neuroscience , vol.13 , pp. 1189-1215
    • Freund, T.F.1    Powell, J.F.2    Smith, A.D.3
  • 32
    • 24944568237 scopus 로고    scopus 로고
    • A functional MRI study of the effects of bromocriptine, a dopamine receptor agonist, on component processes of working memory
    • Gibbs SE, D'Esposito M (2005). A functional MRI study of the effects of bromocriptine, a dopamine receptor agonist, on component processes of working memory. Psychopharmacology (Berl) 180: 644-653.
    • (2005) Psychopharmacology (Berl) , vol.180 , pp. 644-653
    • Gibbs, S.E.1    D'Esposito, M.2
  • 33
    • 0033985644 scopus 로고    scopus 로고
    • Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia
    • Glantz LA, Lewis DA (2000). Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia. Arch Gen Psychiatry 57: 65-73.
    • (2000) Arch Gen Psychiatry , vol.57 , pp. 65-73
    • Glantz, L.A.1    Lewis, D.A.2
  • 34
    • 0030460739 scopus 로고    scopus 로고
    • Regional and cellular fractionation of working memory
    • Goldman-Rakic PS (1996). Regional and cellular fractionation of working memory. Proc Natl Acad Sci USA 93: 13473-13480.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 13473-13480
    • Goldman-Rakic, P.S.1
  • 35
    • 0033009336 scopus 로고    scopus 로고
    • The 'psychic' neuron of the cerebral cortex
    • Goldman-Rakic PS (1999). The 'psychic' neuron of the cerebral cortex. Ann NY Acad Sci 868: 13-26.
    • (1999) Ann NY Acad Sci , vol.868 , pp. 13-26
    • Goldman-Rakic, P.S.1
  • 37
    • 0030858125 scopus 로고    scopus 로고
    • Functional and anatomical aspects of prefrontal pathology in schizophrenia
    • Goldman-Rakic PS, Selemon LD (1997). Functional and anatomical aspects of prefrontal pathology in schizophrenia. Schizophr Bull 23: 437-458.
    • (1997) Schizophr Bull , vol.23 , pp. 437-458
    • Goldman-Rakic, P.S.1    Selemon, L.D.2
  • 40
    • 33748757320 scopus 로고    scopus 로고
    • Subchronic phencyclidine treatment decreases the number of dendritic spine synapses in the rat prefrontal cortex
    • Hajszan T, Leranth C, Roth RH (2006). Subchronic phencyclidine treatment decreases the number of dendritic spine synapses in the rat prefrontal cortex. Biol Psychiatry 60: 639-644.
    • (2006) Biol Psychiatry , vol.60 , pp. 639-644
    • Hajszan, T.1    Leranth, C.2    Roth, R.H.3
  • 41
    • 0042831054 scopus 로고    scopus 로고
    • Presynaptic proteins in the prefrontal cortex of patients with schizophrenia and rats with abnormal prefrontal development
    • Halim ND, Weickert CS, McClintock BW, Hyde TM, Weinberger DR, Kleinman JE et al (2003). Presynaptic proteins in the prefrontal cortex of patients with schizophrenia and rats with abnormal prefrontal development. Mol Psychiatry 8: 797-810.
    • (2003) Mol Psychiatry , vol.8 , pp. 797-810
    • Halim, N.D.1    Weickert, C.S.2    McClintock, B.W.3    Hyde, T.M.4    Weinberger, D.R.5    Kleinman, J.E.6
  • 42
    • 33645633313 scopus 로고    scopus 로고
    • Estrogen alters spine number and morphology in prefrontal cortex of aged female rhesus monkeys
    • Hao J, Rapp PR, Leffler AE, Leffler SR, Janssen WG, Lou W et al (2006). Estrogen alters spine number and morphology in prefrontal cortex of aged female rhesus monkeys. J Neurosci 26: 2571-2578.
    • (2006) J Neurosci , vol.26 , pp. 2571-2578
    • Hao, J.1    Rapp, P.R.2    Leffler, A.E.3    Leffler, S.R.4    Janssen, W.G.5    Lou, W.6
  • 43
    • 0032924127 scopus 로고    scopus 로고
    • The neuropathology of schizophrenia. A critical review of the data and their interpretation
    • Harrison PJ (1999). The neuropathology of schizophrenia. A critical review of the data and their interpretation. Brain 122(Part 4): 593-624.
    • (1999) Brain , vol.122 , Issue.PART 4 , pp. 593-624
    • Harrison, P.J.1
  • 44
    • 33745698814 scopus 로고    scopus 로고
    • Molecular mechanisms contributing to dendritic spine alterations in the prefrontal cortex of subjects with schizophrenia
    • Hill JJ, Hashimoto T, Lewis DA (2006). Molecular mechanisms contributing to dendritic spine alterations in the prefrontal cortex of subjects with schizophrenia. Mol Psychiat 11: 557-566.
    • (2006) Mol Psychiat , vol.11 , pp. 557-566
    • Hill, J.J.1    Hashimoto, T.2    Lewis, D.A.3
  • 45
    • 0037839787 scopus 로고    scopus 로고
    • Loss and altered spatial distribution of oligodendrocytes in the superior frontal gyrus in schizophrenia
    • Hof PR, Haroutunian V, Friedrich Jr VL, Byne W, Buitron C, Perl DP et al (2003). Loss and altered spatial distribution of oligodendrocytes in the superior frontal gyrus in schizophrenia. Biol Psychiatry 53: 1075-1085.
    • (2003) Biol Psychiatry , vol.53 , pp. 1075-1085
    • Hof, P.R.1    Haroutunian, V.2    Friedrich Jr, V.L.3    Byne, W.4    Buitron, C.5    Perl, D.P.6
  • 46
    • 0024326094 scopus 로고
    • Spine density on neostriatal neurones changes with 6-hydroxydopamine lesions and with age
    • Ingham CA, Hood SH, Arbuthnott GW (1989). Spine density on neostriatal neurones changes with 6-hydroxydopamine lesions and with age. Brain Res 503: 334-338.
    • (1989) Brain Res , vol.503 , pp. 334-338
    • Ingham, C.A.1    Hood, S.H.2    Arbuthnott, G.W.3
  • 47
    • 33744991083 scopus 로고    scopus 로고
    • Brief uncontrollable stress causes dendritic retraction in infralimbic cortex and resistance to fear extinction in mice
    • Izquierdo A, Wellman CL, Holmes A (2006). Brief uncontrollable stress causes dendritic retraction in infralimbic cortex and resistance to fear extinction in mice. J Neurosci 26: 5733-5738.
    • (2006) J Neurosci , vol.26 , pp. 5733-5738
    • Izquierdo, A.1    Wellman, C.L.2    Holmes, A.3
  • 48
    • 0023870096 scopus 로고
    • Development of the dopaminergic innervation in the prefrontal cortex of the rat
    • Kalsbeek A, Voorn P, Buijs RM, Pool CW, Uylings HB (1988). Development of the dopaminergic innervation in the prefrontal cortex of the rat. J Comp Neurol 269: 58-72.
    • (1988) J Comp Neurol , vol.269 , pp. 58-72
    • Kalsbeek, A.1    Voorn, P.2    Buijs, R.M.3    Pool, C.W.4    Uylings, H.B.5
  • 49
    • 0034626870 scopus 로고    scopus 로고
    • The dendritic architecture of prefrontal pyramidal neurons in schizophrenic patients
    • Kalus P, Muller TJ, Zuschratter W, Senitz D (2000). The dendritic architecture of prefrontal pyramidal neurons in schizophrenic patients. Neuroreport 11: 3621-3625.
    • (2000) Neuroreport , vol.11 , pp. 3621-3625
    • Kalus, P.1    Muller, T.J.2    Zuschratter, W.3    Senitz, D.4
  • 50
    • 34247643916 scopus 로고    scopus 로고
    • Neurocognitive effects of antipsychotic medications in patients with chronic schizophrenia in the CATIE Trial
    • Keefe RS, Bilder RM, Davis SM, Harvey PD, Palmer BW, Gold JM et al (2007). Neurocognitive effects of antipsychotic medications in patients with chronic schizophrenia in the CATIE Trial. Arch Gen Psychiatry 64: 633-647.
    • (2007) Arch Gen Psychiatry , vol.64 , pp. 633-647
    • Keefe, R.S.1    Bilder, R.M.2    Davis, S.M.3    Harvey, P.D.4    Palmer, B.W.5    Gold, J.M.6
  • 51
    • 2942565924 scopus 로고    scopus 로고
    • Comparative effect of atypical and conventional antipsychotic drugs on neurocognition in first-episode psychosis: A randomized, double-blind trial of olanzapine versus low doses of haloperidol
    • Keefe RS, Seidman LJ, Christensen BK, Hamer RM, Sharma T, Sitskoorn MM et al (2004). Comparative effect of atypical and conventional antipsychotic drugs on neurocognition in first-episode psychosis: a randomized, double-blind trial of olanzapine versus low doses of haloperidol. Am J Psychiatry 161: 985-995.
    • (2004) Am J Psychiatry , vol.161 , pp. 985-995
    • Keefe, R.S.1    Seidman, L.J.2    Christensen, B.K.3    Hamer, R.M.4    Sharma, T.5    Sitskoorn, M.M.6
  • 52
    • 0030964194 scopus 로고    scopus 로고
    • Dopamine, the prefrontal cortex and schizophrenia
    • Knable MB, Weinberger DR (1997). Dopamine, the prefrontal cortex and schizophrenia. J Psychopharmacol 11: 123-131.
    • (1997) J Psychopharmacol , vol.11 , pp. 123-131
    • Knable, M.B.1    Weinberger, D.R.2
  • 53
    • 0041836229 scopus 로고    scopus 로고
    • Amphetamine or cocaine limits the ability of later experience to promote structural plasticity in the neocortex and nucleus accumbens
    • Kolb B, Gorny G, Li Y, Samaha AN, Robinson TE (2003). Amphetamine or cocaine limits the ability of later experience to promote structural plasticity in the neocortex and nucleus accumbens. Proc Natl Acad Sci USA 100: 10523-10528.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 10523-10528
    • Kolb, B.1    Gorny, G.2    Li, Y.3    Samaha, A.N.4    Robinson, T.E.5
  • 54
    • 20044380772 scopus 로고    scopus 로고
    • Lamina-specific reductions in dendritic spine density in the prefrontal cortex of subjects with schizophrenia
    • Kolluri N, Sun Z, Sampson AR, Lewis DA (2005). Lamina-specific reductions in dendritic spine density in the prefrontal cortex of subjects with schizophrenia. Am J Psychiatry 162: 1200-1202.
    • (2005) Am J Psychiatry , vol.162 , pp. 1200-1202
    • Kolluri, N.1    Sun, Z.2    Sampson, A.R.3    Lewis, D.A.4
  • 55
    • 0017343846 scopus 로고
    • The cortical projections of the mediodorsal nucleus and adjacent thalamic nuclei in the rat
    • Krettek JE, Price JL (1977). The cortical projections of the mediodorsal nucleus and adjacent thalamic nuclei in the rat. J Comp Neurol 171: 157-191.
    • (1977) J Comp Neurol , vol.171 , pp. 157-191
    • Krettek, J.E.1    Price, J.L.2
  • 56
    • 0033638576 scopus 로고    scopus 로고
    • Catching up on schizophrenia: Natural history and neurobiology
    • Lewis DA, Lieberman JA (2000). Catching up on schizophrenia: natural history and neurobiology. Neuron 28: 325-334.
    • (2000) Neuron , vol.28 , pp. 325-334
    • Lewis, D.A.1    Lieberman, J.A.2
  • 57
    • 0031933103 scopus 로고    scopus 로고
    • Olanzapine increases in vivo dopamine and norepinephrine release in rat prefrontal cortex, nucleus accumbens and striatum
    • Li XM, Perry KW, Wong DT, Bymaster FP (1998). Olanzapine increases in vivo dopamine and norepinephrine release in rat prefrontal cortex, nucleus accumbens and striatum. Psychopharmacology (Berl) 136: 153-161.
    • (1998) Psychopharmacology (Berl) , vol.136 , pp. 153-161
    • Li, X.M.1    Perry, K.W.2    Wong, D.T.3    Bymaster, F.P.4
  • 60
    • 0033598803 scopus 로고    scopus 로고
    • Cognition, schizophrenia, and the atypical antipsychotic drugs
    • Meltzer HY, Park S, Kessler R (1999). Cognition, schizophrenia, and the atypical antipsychotic drugs. Proc Natl Acad Sci USA 96: 13591-13593.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 13591-13593
    • Meltzer, H.Y.1    Park, S.2    Kessler, R.3
  • 62
    • 0035426751 scopus 로고    scopus 로고
    • Analysis of complex brain disorders with gene expression microarrays: Schizophrenia as a disease of the synapse
    • Mirnics K, Middleton FA, Lewis DA, Levitt P (2001). Analysis of complex brain disorders with gene expression microarrays: schizophrenia as a disease of the synapse. Trends Neurosci 24: 479-486.
    • (2001) Trends Neurosci , vol.24 , pp. 479-486
    • Mirnics, K.1    Middleton, F.A.2    Lewis, D.A.3    Levitt, P.4
  • 63
    • 33748751056 scopus 로고    scopus 로고
    • Changes of spine density and dendritic complexity in the prefrontal cortex in offspring of mothers exposed to stress during pregnancy
    • Murmu MS, Salomon S, Biala Y, Weinstock M, Braun K, Bock J (2006). Changes of spine density and dendritic complexity in the prefrontal cortex in offspring of mothers exposed to stress during pregnancy. Eur J Neurosci 24: 1477-1487.
    • (2006) Eur J Neurosci , vol.24 , pp. 1477-1487
    • Murmu, M.S.1    Salomon, S.2    Biala, Y.3    Weinstock, M.4    Braun, K.5    Bock, J.6
  • 64
    • 0026485577 scopus 로고
    • Schizophrenics show spatial working memory deficits
    • Park S, Holzman PS (1992). Schizophrenics show spatial working memory deficits. Arch Gen Psychiatry 49: 975-982.
    • (1992) Arch Gen Psychiatry , vol.49 , pp. 975-982
    • Park, S.1    Holzman, P.S.2
  • 65
    • 42049102620 scopus 로고    scopus 로고
    • Perez-Costas E, Guidetti P, Leeley JJ, Melendez-Ferro M, Roberts RC (2005). Neuroleptic and animals models: feasibility of oral treatment monitored by plasma levels and receptor occupancy assays. Soc Neurosci (Abstr 914.18).
    • Perez-Costas E, Guidetti P, Leeley JJ, Melendez-Ferro M, Roberts RC (2005). Neuroleptic and animals models: feasibility of oral treatment monitored by plasma levels and receptor occupancy assays. Soc Neurosci (Abstr 914.18).
  • 66
    • 0037771074 scopus 로고    scopus 로고
    • Somal size of prefrontal cortical pyramidal neurons in schizophrenia: Differential effects across neuronal subpopulations
    • Pierri JN, Volk CL, Auh S, Sampson A, Lewis DA (2003). Somal size of prefrontal cortical pyramidal neurons in schizophrenia: differential effects across neuronal subpopulations. Biol Psychiatry 54: 111-120.
    • (2003) Biol Psychiatry , vol.54 , pp. 111-120
    • Pierri, J.N.1    Volk, C.L.2    Auh, S.3    Sampson, A.4    Lewis, D.A.5
  • 67
    • 23444432520 scopus 로고    scopus 로고
    • Reversibility of apical dendritic retraction in the rat medial prefrontal cortex following repeated stress
    • Radley JJ, Rocher AB, Janssen WG, Hof PR, McEwen BS, Morrison JH (2005). Reversibility of apical dendritic retraction in the rat medial prefrontal cortex following repeated stress. Exp Neurol 196: 199-203.
    • (2005) Exp Neurol , vol.196 , pp. 199-203
    • Radley, J.J.1    Rocher, A.B.2    Janssen, W.G.3    Hof, P.R.4    McEwen, B.S.5    Morrison, J.H.6
  • 68
    • 1642421311 scopus 로고    scopus 로고
    • Chronic behavioral stress induces apical dendritic reorganization in pyramidal neurons of the medial prefrontal cortex
    • Radley JJ, Sisti HM, Hao J, Rocher AB, McCall T, Hof PR et al (2004). Chronic behavioral stress induces apical dendritic reorganization in pyramidal neurons of the medial prefrontal cortex. Neuroscience 125: 1-6.
    • (2004) Neuroscience , vol.125 , pp. 1-6
    • Radley, J.J.1    Sisti, H.M.2    Hao, J.3    Rocher, A.B.4    McCall, T.5    Hof, P.R.6
  • 69
    • 0036354728 scopus 로고    scopus 로고
    • The effects of prelimbic and infralimbic lesions on working memory for visual objects in rats
    • Ragozzino ME, Detrick S, Kesner RP (2002). The effects of prelimbic and infralimbic lesions on working memory for visual objects in rats. Neurobiol Learn Mem 77: 29-43.
    • (2002) Neurobiol Learn Mem , vol.77 , pp. 29-43
    • Ragozzino, M.E.1    Detrick, S.2    Kesner, R.P.3
  • 70
    • 0033995269 scopus 로고    scopus 로고
    • Destruction and creation of spatial tuning by disinhibition: GABA(A) blockade of prefrontal cortical neurons engaged by working memory
    • Rao SG, Williams GV, Goldman-Rakic PS (2000). Destruction and creation of spatial tuning by disinhibition: GABA(A) blockade of prefrontal cortical neurons engaged by working memory. J Neurosci 20: 485-494.
    • (2000) J Neurosci , vol.20 , pp. 485-494
    • Rao, S.G.1    Williams, G.V.2    Goldman-Rakic, P.S.3
  • 71
    • 0035283646 scopus 로고    scopus 로고
    • Cocaine self-administration alters the morphology of dendrites and dendritic spines in the nucleus accumbens and neocortex
    • Robinson TE, Gorny G, Mitton E, Kolb B (2001). Cocaine self-administration alters the morphology of dendrites and dendritic spines in the nucleus accumbens and neocortex. Synapse 39: 257-266.
    • (2001) Synapse , vol.39 , pp. 257-266
    • Robinson, T.E.1    Gorny, G.2    Mitton, E.3    Kolb, B.4
  • 72
    • 0037114066 scopus 로고    scopus 로고
    • Widespread but regionally specific effects of experimenter- versus self-administered morphine on dendritic spines in the nucleus accumbens, hippocampus, and neocortex of adult rats
    • Robinson TE, Gorny G, Savage VR, Kolb B (2002). Widespread but regionally specific effects of experimenter- versus self-administered morphine on dendritic spines in the nucleus accumbens, hippocampus, and neocortex of adult rats. Synapse 46: 271-279.
    • (2002) Synapse , vol.46 , pp. 271-279
    • Robinson, T.E.1    Gorny, G.2    Savage, V.R.3    Kolb, B.4
  • 73
    • 0030732153 scopus 로고    scopus 로고
    • Persistent structural modifications in nucleus accumbens and prefrontal cortex neurons produced by previous experience with amphetamine
    • Robinson TE, Kolb B (1997). Persistent structural modifications in nucleus accumbens and prefrontal cortex neurons produced by previous experience with amphetamine. J Neurosci 17: 8491-8497.
    • (1997) J Neurosci , vol.17 , pp. 8491-8497
    • Robinson, T.E.1    Kolb, B.2
  • 74
    • 0032905108 scopus 로고    scopus 로고
    • Alterations in the morphology of dendrites and dendritic spines in the nucleus accumbens and prefrontal cortex following repeated treatment with amphetamine or cocaine
    • Robinson TE, Kolb B (1999). Alterations in the morphology of dendrites and dendritic spines in the nucleus accumbens and prefrontal cortex following repeated treatment with amphetamine or cocaine. Eur J Neurosci 11: 1598-1604.
    • (1999) Eur J Neurosci , vol.11 , pp. 1598-1604
    • Robinson, T.E.1    Kolb, B.2
  • 75
    • 0020578137 scopus 로고
    • Reduction of cortical dopamine, noradrenaline, serotonin and their metabolites in Parkinson's disease
    • Scatton B, Javoy-Agid F, Rouquier L, Dubois B, Agid Y (1983). Reduction of cortical dopamine, noradrenaline, serotonin and their metabolites in Parkinson's disease. Brain Res 275: 321-328.
    • (1983) Brain Res , vol.275 , pp. 321-328
    • Scatton, B.1    Javoy-Agid, F.2    Rouquier, L.3    Dubois, B.4    Agid, Y.5
  • 76
    • 0033729918 scopus 로고    scopus 로고
    • Dendritic spines shaped by synaptic activity
    • Segal M, Andersen P (2000). Dendritic spines shaped by synaptic activity. Curr Opin Neurobiol 10: 582-586.
    • (2000) Curr Opin Neurobiol , vol.10 , pp. 582-586
    • Segal, M.1    Andersen, P.2
  • 77
    • 0037472343 scopus 로고    scopus 로고
    • Daily injections alter spine density in rat medial prefrontal cortex
    • Seib LM, Wellman CL (2003). Daily injections alter spine density in rat medial prefrontal cortex. Neurosci Lett 337: 29-32.
    • (2003) Neurosci Lett , vol.337 , pp. 29-32
    • Seib, L.M.1    Wellman, C.L.2
  • 78
    • 0032967531 scopus 로고    scopus 로고
    • The reduced neuropil hypothesis: A circuit based model of schizophrenia
    • Selemon LD, Goldman-Rakic PS (1999). The reduced neuropil hypothesis: a circuit based model of schizophrenia. Biol Psychiatry 45: 17-25.
    • (1999) Biol Psychiatry , vol.45 , pp. 17-25
    • Selemon, L.D.1    Goldman-Rakic, P.S.2
  • 79
    • 0033058874 scopus 로고    scopus 로고
    • Increased volume and glial density in primate prefrontal cortex associated with chronic antipsychotic drug exposure
    • Selemon LD, Lidow MS, Goldman-Rakic PS (1999). Increased volume and glial density in primate prefrontal cortex associated with chronic antipsychotic drug exposure. Biol Psychiatry 46: 161-172.
    • (1999) Biol Psychiatry , vol.46 , pp. 161-172
    • Selemon, L.D.1    Lidow, M.S.2    Goldman-Rakic, P.S.3
  • 80
    • 0347091942 scopus 로고    scopus 로고
    • Anatomical substrates for glutamate-dopamine interactions: Evidence for specificity of connections and extrasynaptic actions
    • Sesack SR, Carr DB, Omelchenko N, Pinto A (2003). Anatomical substrates for glutamate-dopamine interactions: evidence for specificity of connections and extrasynaptic actions. Ann NY Acad Sci 1003: 36-52.
    • (2003) Ann NY Acad Sci , vol.1003 , pp. 36-52
    • Sesack, S.R.1    Carr, D.B.2    Omelchenko, N.3    Pinto, A.4
  • 81
    • 0032054478 scopus 로고    scopus 로고
    • Dopamine axon varicosities in the prelimbic division of the rat prefrontal cortex exhibit sparse immunoreactivity for the dopamine transporter
    • Sesack SR, Hawrylak VA, Matus C, Guido MA, Levey AI (1998). Dopamine axon varicosities in the prelimbic division of the rat prefrontal cortex exhibit sparse immunoreactivity for the dopamine transporter. J Neurosci 18: 2697-2708.
    • (1998) J Neurosci , vol.18 , pp. 2697-2708
    • Sesack, S.R.1    Hawrylak, V.A.2    Matus, C.3    Guido, M.A.4    Levey, A.I.5
  • 82
    • 27744446263 scopus 로고    scopus 로고
    • Selective acetylcholine and dopamine lesions in neonatal rats produce distinct patterns of cortical dendritic atrophy in adulthood
    • Sherren N, Pappas BA (2005). Selective acetylcholine and dopamine lesions in neonatal rats produce distinct patterns of cortical dendritic atrophy in adulthood. Neuroscience 136: 445-456.
    • (2005) Neuroscience , vol.136 , pp. 445-456
    • Sherren, N.1    Pappas, B.A.2
  • 83
    • 34147177023 scopus 로고    scopus 로고
    • Alterations in dendritic morphology of the prefrontal cortical and striatum neurons in the unilateral 6-OHDA-rat model of Parkinson's disease
    • Solis O, Limón DI, Flores-Hernández J, Flores G (2007). Alterations in dendritic morphology of the prefrontal cortical and striatum neurons in the unilateral 6-OHDA-rat model of Parkinson's disease. Synapse 61: 450-458.
    • (2007) Synapse , vol.61 , pp. 450-458
    • Solis, O.1    Limón, D.I.2    Flores-Hernández, J.3    Flores, G.4
  • 84
    • 19544370363 scopus 로고    scopus 로고
    • Anatomical abnormalities in dopaminoceptive regions of the cerebral cortex of dopamine D1 receptor mutant mice
    • Stanwood GD, Parlaman JP, Levitt P (2005). Anatomical abnormalities in dopaminoceptive regions of the cerebral cortex of dopamine D1 receptor mutant mice. J Comp Neurol 487: 270-282.
    • (2005) J Comp Neurol , vol.487 , pp. 270-282
    • Stanwood, G.D.1    Parlaman, J.P.2    Levitt, P.3
  • 87
    • 0035080414 scopus 로고    scopus 로고
    • No deficit in total number of neurons in the prefrontal cortex in schizophrenics
    • Thune JJ, Uylings HB, Pakkenberg B (2001). No deficit in total number of neurons in the prefrontal cortex in schizophrenics. J Psychiatr Res 35: 15-21.
    • (2001) J Psychiatr Res , vol.35 , pp. 15-21
    • Thune, J.J.1    Uylings, H.B.2    Pakkenberg, B.3
  • 89
    • 0023408490 scopus 로고
    • Immunocytochemical localization of dopamine in the prefrontal cortex of the rat at the light and electron microscopical level
    • Van Eden CG, Hoorneman EM, Buijs RM, Matthijssen MA, Geffard M, Uylings HB (1987). Immunocytochemical localization of dopamine in the prefrontal cortex of the rat at the light and electron microscopical level. Neuroscience 22: 849-862.
    • (1987) Neuroscience , vol.22 , pp. 849-862
    • Van Eden, C.G.1    Hoorneman, E.M.2    Buijs, R.M.3    Matthijssen, M.A.4    Geffard, M.5    Uylings, H.B.6
  • 90
    • 0036159250 scopus 로고    scopus 로고
    • Clozapine, olanzapine, risperidone, and haloperidol in the treatment of patients with chronic schizophrenia and schizoaffective disorder
    • Volavka J, Czobor P, Sheitman B, Lindenmayer JP, Citrome L, McEvoy JP et al (2002). Clozapine, olanzapine, risperidone, and haloperidol in the treatment of patients with chronic schizophrenia and schizoaffective disorder. Am J Psychiatry 159: 255-262.
    • (2002) Am J Psychiatry , vol.159 , pp. 255-262
    • Volavka, J.1    Czobor, P.2    Sheitman, B.3    Lindenmayer, J.P.4    Citrome, L.5    McEvoy, J.P.6
  • 92
    • 0023918477 scopus 로고
    • Physiological dysfunction of dorsolateral prefrontal cortex in schizophrenia. III. A new cohort and evidence for a monoaminergic mechanism
    • Weinberger DR, Berman KF, Illowsky BP (1988). Physiological dysfunction of dorsolateral prefrontal cortex in schizophrenia. III. A new cohort and evidence for a monoaminergic mechanism. Arch Gen Psychiatry 45: 609-615.
    • (1988) Arch Gen Psychiatry , vol.45 , pp. 609-615
    • Weinberger, D.R.1    Berman, K.F.2    Illowsky, B.P.3
  • 93
    • 0027972670 scopus 로고
    • Preferential activation of dopamine overflow in prefrontal cortex produced by chronic clozapine treatment
    • Youngren KD, Moghaddam B, Bunney BS, Roth RH (1994). Preferential activation of dopamine overflow in prefrontal cortex produced by chronic clozapine treatment. Neurosci Lett 165: 41-44.
    • (1994) Neurosci Lett , vol.165 , pp. 41-44
    • Youngren, K.D.1    Moghaddam, B.2    Bunney, B.S.3    Roth, R.H.4


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