The 'Psychic' neuron of the cerebral cortex

Annals of the New York Academy of Sciences

Volumn 868, Issue , 1999, Pages 13-26

  Goldman Rakic, Patricia S ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; DOPAMINE; DOPAMINE RECEPTOR; GLUTAMIC ACID; ION CHANNEL; NEUROTRANSMITTER; NEUROTRANSMITTER RECEPTOR; RECEPTOR; SEROTONIN; SEROTONIN RECEPTOR;

BIOPHYSICS; BRAIN CORTEX; CENTRAL NERVOUS SYSTEM; CLONING; CONFERENCE PAPER; EXCITABILITY; INFORMATION PROCESSING; INNERVATION; MEMORY; NERVE CELL; NEUROBIOLOGY; NONHUMAN; PERFORMANCE; PREFRONTAL CORTEX; PRIMATE; PROTEIN LOCALIZATION; PYRAMIDAL NERVE CELL; WORKING MEMORY;

PRIMATES;

EID: 0033009336     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1999.tb11270.x     Document Type: Conference Paper

References (45)

1. Baddeley, A. 1986. Working Memory. Oxford University Press, London.
2. Just, M.A. & P.A. Carpenter. 1992. A capacity theory of comprehension: Individual differences in working memory. Psych. Rev. 99: 122-149.
3. Fuster, J.M. & G.E. Alexander. 1971. Neuron activity related to short-term memory. Science 173: 652-654.
4. Kubota, K. & H. Niki. 1971. Prefrontal cortical unit activity and delayed alternation performance in monkeys. J. Neurophysiol. 34: 337-347.
5. Funahashi, S., C.J. Bruce & P.S. Goldman-Rakic. 1989. Mnemonic coding of visual space in the monkey's dorsolateral prefrontal cortex. J. Neurophysiol. 61: 331-349.
6. Fuster, J.M. 1973. Unit activity in prefrontal cortex during delayed-response performance: Neuronal correlates of transient memory. J. Neurophysiol. 36: 61-78.
7. Funahashi, S., M.V. Chafee & P.S. Goldman-Rakic. 1993. Prefrontal neuronal activity in rhesus monkeys performing a delayed anti-saccade task. Nature 365: 753-756.
8. Wilson, F.A.W., S.P.O Scalaidhe & P.S. Goldman-Rakic. 1993. Dissociation of object and spatial processing domains in primate prefrontal cortex. Science 260: 1955-1958.
9. Ó Scalaidhe, S.P., F.A.W, Wilson & P.S. Goldman-Rakic. 1997. Areal segregation of face-processing neurons in prefrontal cortex. Science 278: 1135-1138.
10. Mountcastle, V.B., V.M. Talbot, H. Sakata & J. Hyvarinen. 1969. Cortical neuronal mechanisms in flutter-vibration studied in unanesthetized monkeys. Neuronal periodicity and frequency discrimination. J. Neurophysiol. 32: 452-484.
11. McCormick, D.A., B.W. Connors, J.W. Lighthall & D.A. Prince. 1985. Comparative electro-physiology of pyramidal and sparsely spiny stellate neurons of the neocortex. J. Neurophysiol. 54: 782-806.
12. Kawaguchi, Y. 1995. Physiological subgroups of nonpyramidal cells with specific morphological characteristics in layer II/III of rat frontal cortex. J. Neurosci. 15: 2638-2655.
13. Martin, K.A., P. Somogyi & D. Whitteridge. 1983. Physiological and morphological properties of identified basket cells in the cat's visual cortex. Exp. Brain Res. 50: 193-200.
14. Williams, S.M., P.S. Goldman-Rakic & C. Leranth. 1992. The synaptology of parvalbumin-immunorcactive neurons in the primate prefrontal cortex. J. Comp. Neurol. 320: 353-369.
15. Rao, S., G.V. Williams & P.S. Goldman-Rakic. Iso-directional spatial tuning if adjacent putative intemourons and pyramidal neurons during working memory: Functional evidence for a microcolumnar organization in primate prefrontal cortex. J. Neurophysiol. In press.
16. Williams, S.M. & P.S. Goldman-Rakic. 1993. Characterization of the dopaminergic innervation of the primate frontal cortex using a dopamine-specific antibody. Cereb. Cortex 3: 199-222.
17. Williams, S.M. & P.S. Goldman-Rakic. 1998. Widespread origin of the primate mesofrontal dopamine system. Cereb. Cortex 8: 321-345.
18. 2A serotonin receptors in the primate cerebral cortex: Possible site of action of hallucinogenic and antipsychotic drugs in pyramidal cell apical dendrites. Proc. Natl. Acad. Sci. USA 95: 735-740.
19. Brozoski, T., R.M. Brown, H.E. Rosvold & P.S. Goldman. 1979. Cognitive deficit caused by regional depletion of dopamine in prefrontal cortex of rhesus monkey. Science 205: 929-932.
20. Brown, R.G. & C.D. Marsden. 1988. Internal versus external cues and the control of attention in Parkinson's disease. Brain 111: 323-345.
21. Gotham, A.M., R.G. Brown & C.P. Marsden. 1988. 'Frontal' cognitive function in patients with Parkinson's disease 'on' and 'off' levodopa. Brain 111: 299-321.
22. Goldman-Rakic, P.S., C. Leranth, S.M. Williams, N. Mons & M. Geffard. 1989. Dopamine synaptic complex with pyramidal neurons in primate cerebral cortex. Proc. Natl. Acad. Sci. USA 86: 9015-9019.
23. Smiley, J.F., S.M. Williams, K. Szigeti & P.S. Goldman-Rakic. 1992. Light and electron microscopic characterization of dopamine-immunoreactivc processes in human cerebral cortex. J. Comp. Neurol. 321: 325-335.
24. Smiley, J.F. & P.S. Goldman-Rakic. 1993. Heterogeneous target of dopamine synapses in monkey prefrontal cortex demonstrated by serial section electron microscopy: A laminar analysis using the silver-enhanced diaminobenzidine sulfide (SEDS) immunolabeling technique. Cereb. Cortex 3: 223-238.
25. Goldman-Rakic, P.S., M.S. Lidow & D.W. Gallager. 1990. Overlap of dopaminergic, adrenergic, and serotoninergic receptors and complementarily of their subtypes in primate prefrontal cortex. J. Neurosci. 10: 2125-2138.
26. H]SCH23390. Neuroscience. 40: 657-671.
27. Smiley, J.F., A.I. Levey, B.J. Ciliax & P.S. Goldman-Rakic. 1994. D1 dopamine receptor immunoreactivity in human and monkey cerebral cortex: Predominant and extrasynaptic localization in dendritic spines. Proc. Natl. Acad. Sci. USA 91: 5720-5724.
28. Surtneier, D.J., J. Bargas, H.C. Hemmings, Jr., A.C. Naim & P. Greengard. 1995. Modulation of calcium currents by a D1 dopaminergic protein kinase/phosphatase cascade in rat neostriatal neurons. Neuron 14: 385-397.
29. Calabresi, P., N. Mercuri, P. Stanzione, A. Stefani & G. Bernardi. 1987. Intracellular studies on the dopamine-induced firing inhibition of neostriatal neurons in vitro: Evidence for D1 receptor involvement. Neuroscience 20: 757-771.
30. Uchimura N., H. Higashi & S. Nishi. 1986. Hyperpolarizing and depolarizing actions of dopamine via D-1 and D-2 receptors on nucleus accumbens neurons. Brain Res. 375: 368-372.
31. 2+ conductance. J. Neurosci. 17: 3334-3342.
32. Cepeda, C., N.A. Buchwald & M.S. Levine. 1993. Neuromodulatory actions of dopamine in the neostriatum are dependent upon the excitatory amino acid receptor subtypes activated. Proc. Natl. Acad. Sci. USA 90: 9576-9580.
33. Cepeda, C., C.S. Colwell, J.N. Itri, S.H. Chandler & M.S. Levine. 1998. Dopaminergic modulation of NMDA-induced whole cell currents in neostriatal neurons in slices: Contribution of calcium conductances. J. Neurophysiol. 79: 82-94.
34. Westenbroek, R.E., M.K. Ahhjanian & W.A. Catterall. 1990. Clustering of L-type Ca2+ channels at the base of major dendrites in hippocampal pyramidal neurons. Nature 347: 281-284.
35. 1 subunit. Neuron 9: 1099-1115.
36. 1A sub-units of brain calcium channels. J. Neurosci. 15: 6403-6418.
37. Ahlijanian, M.K., R.E. Westenbroek & W.A. Catterall. 1990. Subunit structure and localization of dihydropyridine-sensitive calcium channels in mammalian brain, spinal cord, and retina. Neuron 4: 819-832.
38. 1 subunits. J. Cell Biol 123: 949-962.
39. Williams, G.V. & P.S. Goldman-Rakic. 1995. Modulation of memory fields by dopamine D1 receptors in prefrontal cortex. Nature 376: 572-575.
40. Lange, K.W., T.W. Robbins, C.D. Marsden, M. James, A.M. Owen & G.M. Paul. 1992. L-dopa withdrawal in Parkinson's disease selectively impairs cognitive performance in tests sensitive to frontal lobe dysfunction. Psychopharmacology 107: 394-404.
41. Murphy, B.L., A.F.T. Arnsten, P.S. Goldman-Rakic & R.H. Roth. 1996. Increased dopamine turnover in the prefrontal cortex impairs spatial working memory performance in rats and monkeys. Proc. Natl. Acad. Sci. USA 93: 1325-1329.
42. Cepeda, C., Z. Radisavijevic, W. Peacock, M.S. Levine & N.A. Buchwald. 1992. Differential modulation by dopamine of responses evoked by excitatory amino acids in human cortex. Synapse 11: 330-341.
43. Yang, C.R. & J.K. Seamans. 1996. Dopamine D1 receptor actions in layers V-VI rat prefrontal cortex neurons in vitro: Modulation of dendritic-somatic signal integration. J. Neurosci. 16: 1922-1935.
44. Lisman, J.E., J-M Fellous & X-J Wang. 1998. A role for the NMDA-receptor channels in working memory. Nature Neuroscience 1: 273-275.
45. Jakab, R.L. & P.S. Goldman-Rakic. 1998. Segregation of 5-HT2A and 5-HT3 serotonin receptors in primate prefrontal cortex. Soc. Neurosci. Abstr. 24: 308.