Inhibition of apoptosis by MAD1 is mediated by repression of the PTEN tumor suppressor gene

FASEB Journal

Volumn 22, Issue 4, 2008, Pages 1124-1134

  Rottmann, Sabine ^a,b   Speckgens, Stefanie ^a   Lüscher Firzlaff, Juliane ^a   Lüscher, Bernhard ^a,c  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION   (United States)

^c UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

Author keywords

AKT; MYC; PI3K; Transcription

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPID; PHOSPHATASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; PROTEIN MAD1; SMALL INTERFERING RNA; TENSIN;

APOPTOSIS; ARTICLE; CELL STRAIN HEK293; CHROMOSOME 10; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; ENZYME ACTIVATION; FEMALE; GENE DELETION; GENE EXPRESSION REGULATION; GENE REPRESSION; HELA CELL; HUMAN; HUMAN CELL; KNOCKOUT GENE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN TARGETING; RNA INTERFERENCE; STIMULATION; TUMOR SUPPRESSOR GENE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; APOPTOSIS; BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; CELL LINE, TUMOR; GENES, TUMOR SUPPRESSOR; HELA CELLS; HUMANS; MICE; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION;

EID: 42049096743     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.07-9627com     Document Type: Article

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