메뉴 건너뛰기




Volumn 49, Issue 3, 2008, Pages 1200-1209

Prevalence and morphology of druse types in the macula and periphery of eyes with age-related maculopathy

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; BRUCH MEMBRANE; CLINICAL ARTICLE; CRYSTALLIZATION; DISEASE COURSE; DISEASE PREDISPOSITION; DRUSEN; FEMALE; HUMAN; LIQUID; MALE; MICROSCOPY; MORPHOLOGY; PARAMETER; PIGMENT EPITHELIUM; PREVALENCE; PRIORITY JOURNAL; RETINA MACULA AGE RELATED DEGENERATION; RETINA MACULA LUTEA; STRUCTURE ANALYSIS; TISSUE DISTRIBUTION; CLASSIFICATION; MIDDLE AGED; PATHOLOGY; RETINA MACULA DEGENERATION; RISK FACTOR;

EID: 41949092443     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.07-1466     Document Type: Article
Times cited : (138)

References (53)
  • 1
    • 0033520641 scopus 로고    scopus 로고
    • Histopathology of age-related macular degeneration
    • Green WR. Histopathology of age-related macular degeneration. Mol Vis. 1999;5:27.
    • (1999) Mol Vis , vol.5 , pp. 27
    • Green, W.R.1
  • 2
    • 0032797880 scopus 로고    scopus 로고
    • Abdelsalam A, Del Priore L, Zarbin MA. Drusen in age-related macular degeneration: pathogenesis, natural course, and laser photocoagulation-induced regression. Surv Ophthalmol. 1999;44:1-29.
    • Abdelsalam A, Del Priore L, Zarbin MA. Drusen in age-related macular degeneration: pathogenesis, natural course, and laser photocoagulation-induced regression. Surv Ophthalmol. 1999;44:1-29.
  • 3
    • 0026681119 scopus 로고
    • Prevalence of age-related maculopathy. The Beaver Dam Eye Study
    • Klein R, Klein BE, Linton KL. Prevalence of age-related maculopathy. The Beaver Dam Eye Study. Ophthalmology. 1992;99:933-943.
    • (1992) Ophthalmology , vol.99 , pp. 933-943
    • Klein, R.1    Klein, B.E.2    Linton, K.L.3
  • 6
    • 0028934221 scopus 로고
    • An international classification and grading system for age-related maculopathy and age-related macular degeneration. The International ARM Epidemiological Study Group
    • Bird AC, Bressler NM, Bressler SB, et al. An international classification and grading system for age-related maculopathy and age-related macular degeneration. The International ARM Epidemiological Study Group. Surv Ophthalmol. 1995;39:367-374.
    • (1995) Surv Ophthalmol , vol.39 , pp. 367-374
    • Bird, A.C.1    Bressler, N.M.2    Bressler, S.B.3
  • 7
    • 27744508407 scopus 로고    scopus 로고
    • The Age-Related Eye Disease Study severity scale for age-related macular degeneration: AREDS Report No. 17
    • Davis MD, Gangnon RE, Lee LY, et al. The Age-Related Eye Disease Study severity scale for age-related macular degeneration: AREDS Report No. 17. Arch Ophthalmol. 2005;123:1484-1498.
    • (2005) Arch Ophthalmol , vol.123 , pp. 1484-1498
    • Davis, M.D.1    Gangnon, R.E.2    Lee, L.Y.3
  • 9
    • 27744516278 scopus 로고    scopus 로고
    • A simplified severity scale for age-related macular degeneration: AREDS Report No. 18
    • Ferris FL, Davis MD, Clemons TE, et al. A simplified severity scale for age-related macular degeneration: AREDS Report No. 18. Arch Ophthalmol. 2005;123:1570-1574.
    • (2005) Arch Ophthalmol , vol.123 , pp. 1570-1574
    • Ferris, F.L.1    Davis, M.D.2    Clemons, T.E.3
  • 10
    • 33846472391 scopus 로고    scopus 로고
    • Fifteen-year cumulative incidence of age-related macular degeneration: The Beaver Dam Eye Study
    • Klein R, Klein BE, Knudtson MD, Meuer SM, Swift M, Gangnon RE. Fifteen-year cumulative incidence of age-related macular degeneration: the Beaver Dam Eye Study. Ophthalmology. 2007; 114:253-262.
    • (2007) Ophthalmology , vol.114 , pp. 253-262
    • Klein, R.1    Klein, B.E.2    Knudtson, M.D.3    Meuer, S.M.4    Swift, M.5    Gangnon, R.E.6
  • 11
    • 0036788613 scopus 로고    scopus 로고
    • Ten-year incidence and progression of age-related maculopathy: The Beaver Dam eye study
    • Klein R, Klein BE, Tomany SC, Meuer SM, Huang GH. Ten-year incidence and progression of age-related maculopathy: The Beaver Dam eye study. Ophthalmology. 2002;109:1767-1779.
    • (2002) Ophthalmology , vol.109 , pp. 1767-1779
    • Klein, R.1    Klein, B.E.2    Tomany, S.C.3    Meuer, S.M.4    Huang, G.H.5
  • 12
    • 33845754932 scopus 로고    scopus 로고
    • Ten-year incidence and progression of age-related maculopathy: The blue Mountains Eye Study
    • Wang JJ, Rochtchina E, Lee AJ, et al. Ten-year incidence and progression of age-related maculopathy: the blue Mountains Eye Study. Ophthalmology. 2007;114:92-98.
    • (2007) Ophthalmology , vol.114 , pp. 92-98
    • Wang, J.J.1    Rochtchina, E.2    Lee, A.J.3
  • 13
    • 0345760069 scopus 로고    scopus 로고
    • Characterization of beta amyloid assemblies in drusen: The deposits associated with aging and age-related macular degeneration
    • Anderson DH, Talaga KC, Rivest AJ, Barron E, Hageman GS, Johnson LV. Characterization of beta amyloid assemblies in drusen: the deposits associated with aging and age-related macular degeneration. Exp Eye Res. 2004;78:243-256.
    • (2004) Exp Eye Res , vol.78 , pp. 243-256
    • Anderson, D.H.1    Talaga, K.C.2    Rivest, A.J.3    Barron, E.4    Hageman, G.S.5    Johnson, L.V.6
  • 14
    • 18244421270 scopus 로고    scopus 로고
    • Molecular composition of drusen as related to substructural phenotype
    • Hageman GS, Mullins RF. Molecular composition of drusen as related to substructural phenotype. Mol Vis. 1999;5:28.
    • (1999) Mol Vis , vol.5 , pp. 28
    • Hageman, G.S.1    Mullins, R.F.2
  • 15
    • 34447635912 scopus 로고    scopus 로고
    • Distribution and composition of esterified and unesterified cholesterol in extra-macular drusen
    • Li CM, Clark ME, Rudolf M, Curcio CA. Distribution and composition of esterified and unesterified cholesterol in extra-macular drusen. Exp Eye Res. 2007;85:192-201.
    • (2007) Exp Eye Res , vol.85 , pp. 192-201
    • Li, C.M.1    Clark, M.E.2    Rudolf, M.3    Curcio, C.A.4
  • 16
    • 0037332052 scopus 로고    scopus 로고
    • Apolipoprotein B in cholesterol-containing drusen and basal deposits of human eyes with age-related maculopathy
    • Malek G, Li CM, Guidry C, Medeiros NE, Curcio CA. Apolipoprotein B in cholesterol-containing drusen and basal deposits of human eyes with age-related maculopathy. Am J Pathol. 2003;162: 413-425.
    • (2003) Am J Pathol , vol.162 , pp. 413-425
    • Malek, G.1    Li, C.M.2    Guidry, C.3    Medeiros, N.E.4    Curcio, C.A.5
  • 18
    • 11144258543 scopus 로고    scopus 로고
    • Drusen proteome analysis: An approach to the etiology of age-related macular degeneration
    • Crabb JW, Miyagi M, Gu X, et al. Drusen proteome analysis: an approach to the etiology of age-related macular degeneration. Proc Natl Acad Sci USA. 2002;99:14682-14687.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 14682-14687
    • Crabb, J.W.1    Miyagi, M.2    Gu, X.3
  • 19
    • 0026670743 scopus 로고
    • Correlation between biochemical composition and fluorescein binding of deposits in Bruch's membrane
    • Pauleikhoff D, Zuels S, Sheraidah GS, Marshall J, Wessing A, Bird AC. Correlation between biochemical composition and fluorescein binding of deposits in Bruch's membrane. Ophthalmology. 1992; 99:1548-1553.
    • (1992) Ophthalmology , vol.99 , pp. 1548-1553
    • Pauleikhoff, D.1    Zuels, S.2    Sheraidah, G.S.3    Marshall, J.4    Wessing, A.5    Bird, A.C.6
  • 20
    • 28444468904 scopus 로고    scopus 로고
    • Esterified and unesterified cholesterol in drusen and basal deposits of eyes with age-related maculopathy
    • Curcio CA, Presley JB, Malek G, Medeiros NE, Avery DV, Kruth HS. Esterified and unesterified cholesterol in drusen and basal deposits of eyes with age-related maculopathy. Exp Eye Res. 2005;81:731-741.
    • (2005) Exp Eye Res , vol.81 , pp. 731-741
    • Curcio, C.A.1    Presley, J.B.2    Malek, G.3    Medeiros, N.E.4    Avery, D.V.5    Kruth, H.S.6
  • 21
    • 0032714687 scopus 로고    scopus 로고
    • Human ocular drusen possess novel core domains with a distinct carbohydrate composition
    • Mullins RF, Hageman GS. Human ocular drusen possess novel core domains with a distinct carbohydrate composition. J Histochem Cytochem. 1999;47:1533-1540.
    • (1999) J Histochem Cytochem , vol.47 , pp. 1533-1540
    • Mullins, R.F.1    Hageman, G.S.2
  • 22
    • 0034012166 scopus 로고    scopus 로고
    • Drusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease
    • Mullins RF, Russell SR, Anderson DH, Hageman GS. Drusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease. FASEB J. 2000;14:835-846.
    • (2000) FASEB J , vol.14 , pp. 835-846
    • Mullins, R.F.1    Russell, S.R.2    Anderson, D.H.3    Hageman, G.S.4
  • 23
    • 33947101484 scopus 로고    scopus 로고
    • High concentration of zinc in sub-retinal pigment epithelial deposits
    • Lengyel I, Flinn JM, Peto T, et al. High concentration of zinc in sub-retinal pigment epithelial deposits. Exp Eye Res. 2007;84:772-780.
    • (2007) Exp Eye Res , vol.84 , pp. 772-780
    • Lengyel, I.1    Flinn, J.M.2    Peto, T.3
  • 24
    • 0036741098 scopus 로고    scopus 로고
    • A role for local inflammation in the formation of drusen in the aging eye
    • Anderson DH, Mullins RF, Hageman GS, Johnson LV. A role for local inflammation in the formation of drusen in the aging eye. Am J Ophthalmol. 2002;134:411-431.
    • (2002) Am J Ophthalmol , vol.134 , pp. 411-431
    • Anderson, D.H.1    Mullins, R.F.2    Hageman, G.S.3    Johnson, L.V.4
  • 25
    • 0035699547 scopus 로고    scopus 로고
    • Complement activation and inflammatory processes in Drusen formation and age related macular degeneration
    • Johnson LV, Leitner WP, Staples MK, Anderson DH. Complement activation and inflammatory processes in Drusen formation and age related macular degeneration. Exp Eye Res. 2001;73:887-896.
    • (2001) Exp Eye Res , vol.73 , pp. 887-896
    • Johnson, L.V.1    Leitner, W.P.2    Staples, M.K.3    Anderson, D.H.4
  • 26
    • 0034832029 scopus 로고    scopus 로고
    • An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration
    • Hageman GS, Luthert PJ, Victor Chong NH, Johnson LV, Anderson DH, Mullins RF. An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration. Prog Retin Eye Res. 2001;20:705-732.
    • (2001) Prog Retin Eye Res , vol.20 , pp. 705-732
    • Hageman, G.S.1    Luthert, P.J.2    Victor Chong, N.H.3    Johnson, L.V.4    Anderson, D.H.5    Mullins, R.F.6
  • 27
    • 0000123146 scopus 로고
    • Senile choroidal vascular patterns and drusen
    • Friedman E, Smith TR, Kuwabara T. Senile choroidal vascular patterns and drusen. Arch Ophthalmol. 1962;69:114-124.
    • (1962) Arch Ophthalmol , vol.69 , pp. 114-124
    • Friedman, E.1    Smith, T.R.2    Kuwabara, T.3
  • 28
    • 0023051052 scopus 로고
    • The prevalence of macular drusen in postmortem eyes
    • Lewis H, Straatsma BR, Foos RY. The prevalence of macular drusen in postmortem eyes. Am J Ophthalmol. 1986;102:801-803.
    • (1986) Am J Ophthalmol , vol.102 , pp. 801-803
    • Lewis, H.1    Straatsma, B.R.2    Foos, R.Y.3
  • 29
    • 0022492513 scopus 로고
    • Chorioretinal juncture: Multiple extramacular drusen
    • Lewis H, Straatsma BR, Foos RY. Chorioretinal juncture: multiple extramacular drusen. Ophthalmology. 1986;93:1098-1112.
    • (1986) Ophthalmology , vol.93 , pp. 1098-1112
    • Lewis, H.1    Straatsma, B.R.2    Foos, R.Y.3
  • 31
    • 0038667890 scopus 로고    scopus 로고
    • Risk of age-related macular degeneration in eyes with macular drusen or hyperpigmentation: The Blue Mountains Eye Study cohort
    • Wang JJ, Foran S, Smith W, Mitchell P. Risk of age-related macular degeneration in eyes with macular drusen or hyperpigmentation: the Blue Mountains Eye Study cohort. Arch Ophthalmol. 2003; 121:658-663.
    • (2003) Arch Ophthalmol , vol.121 , pp. 658-663
    • Wang, J.J.1    Foran, S.2    Smith, W.3    Mitchell, P.4
  • 32
    • 34047244381 scopus 로고    scopus 로고
    • Relationship of basal laminar deposit and membranous debris to the clinical presentation of early age-related macular degeneration
    • Sarks S, Cherepanoff S, Killingsworth M, Sarks J. Relationship of basal laminar deposit and membranous debris to the clinical presentation of early age-related macular degeneration. Invest Ophthalmol Vis Sci. 2007;48:968-977.
    • (2007) Invest Ophthalmol Vis Sci , vol.48 , pp. 968-977
    • Sarks, S.1    Cherepanoff, S.2    Killingsworth, M.3    Sarks, J.4
  • 33
    • 0037975774 scopus 로고    scopus 로고
    • Amyloid-beta is found in drusen from some age-related macular degeneration retinas, but not in drusen from normal retinas
    • Dentchev T, Milam AH, Lee VM, Trojanowski JQ, Dunaief JL. Amyloid-beta is found in drusen from some age-related macular degeneration retinas, but not in drusen from normal retinas. Mol Vis. 2003;9:184-190.
    • (2003) Mol Vis , vol.9 , pp. 184-190
    • Dentchev, T.1    Milam, A.H.2    Lee, V.M.3    Trojanowski, J.Q.4    Dunaief, J.L.5
  • 34
    • 0031806880 scopus 로고    scopus 로고
    • The Alabama Age-Related Macular Degeneration Grading System for donor eyes
    • Curcio CA, Medeiros NE, Millican CL. The Alabama Age-Related Macular Degeneration Grading System for donor eyes. Invest Ophthalmol Vis Sci. 1998;39:1085-1096.
    • (1998) Invest Ophthalmol Vis Sci , vol.39 , pp. 1085-1096
    • Curcio, C.A.1    Medeiros, N.E.2    Millican, C.L.3
  • 35
    • 33746551720 scopus 로고    scopus 로고
    • Apolipoprotein localization in isolated drusen and retinal apolipoprotein gene expression
    • Li CM, Clark ME, Chimento MF, Curcio CA. Apolipoprotein localization in isolated drusen and retinal apolipoprotein gene expression. Invest Ophthalmol Vis Sci. 2006;47:3119-3128.
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , pp. 3119-3128
    • Li, C.M.1    Clark, M.E.2    Chimento, M.F.3    Curcio, C.A.4
  • 36
    • 0004229526 scopus 로고
    • Chicago: University of Chicago;
    • Polyak SL. The Retina. Chicago: University of Chicago; 1941.
    • (1941) The Retina
    • Polyak, S.L.1
  • 37
    • 0033040280 scopus 로고    scopus 로고
    • Early drusen formation in the normal and aging eye and their relation to age related maculopathy: A clinicopathological study
    • Sarks SH, Arnold JJ, Killingsworth MC, Sarks JP. Early drusen formation in the normal and aging eye and their relation to age related maculopathy: a clinicopathological study. Br J Ophthalmol. 1999;83:358-368.
    • (1999) Br J Ophthalmol , vol.83 , pp. 358-368
    • Sarks, S.H.1    Arnold, J.J.2    Killingsworth, M.C.3    Sarks, J.P.4
  • 38
    • 0023724421 scopus 로고
    • Ultrastructural discrimination of lipid droplets and vesicles in atherosclerosis: Value of osmium-thiocarbohydrazide-osmium and tannic acid-paraphenylenediamine techniques
    • Guyton JR, Klemp KF. Ultrastructural discrimination of lipid droplets and vesicles in atherosclerosis: value of osmium-thiocarbohydrazide-osmium and tannic acid-paraphenylenediamine techniques. J Histochem Cytochem. 1988;36:1319-1328.
    • (1988) J Histochem Cytochem , vol.36 , pp. 1319-1328
    • Guyton, J.R.1    Klemp, K.F.2
  • 39
    • 0027452475 scopus 로고
    • Age-related macular degeneration histopathologic studies. The 1992 Lorenz E. Zimmerman Lecture
    • Green WR, Enger C. Age-related macular degeneration histopathologic studies. The 1992 Lorenz E. Zimmerman Lecture. Ophthalmology. 1993;100:1519-1535.
    • (1993) Ophthalmology , vol.100 , pp. 1519-1535
    • Green, W.R.1    Enger, C.2
  • 40
    • 0021856681 scopus 로고
    • Pathologic features of senile macular degeneration
    • Green WR, McDonnell PJ, Yeo JH. Pathologic features of senile macular degeneration. Ophthalmology. 1985;92:615-627.
    • (1985) Ophthalmology , vol.92 , pp. 615-627
    • Green, W.R.1    McDonnell, P.J.2    Yeo, J.H.3
  • 41
    • 0028240206 scopus 로고
    • Evolution of soft drusen in age-related macular degeneration
    • Sarks JP, Sarks SH, Killingsworth MC. Evolution of soft drusen in age-related macular degeneration. Eye (Lond). 1994;8:269-283.
    • (1994) Eye (Lond) , vol.8 , pp. 269-283
    • Sarks, J.P.1    Sarks, S.H.2    Killingsworth, M.C.3
  • 42
    • 0017078404 scopus 로고
    • Ageing and degeneration in the macular region: A clinicopathological study
    • Sarks SH. Ageing and degeneration in the macular region: a clinicopathological study. Br J Ophthalmol. 1976;60:324-341.
    • (1976) Br J Ophthalmol , vol.60 , pp. 324-341
    • Sarks, S.H.1
  • 43
    • 0024151007 scopus 로고
    • Evolution of geographic atrophy of the retinal pigment epithelium
    • Sarks JP, Sarks SH, Killingsworth MC. Evolution of geographic atrophy of the retinal pigment epithelium. Eye (Lond). 1988;2: 552-577.
    • (1988) Eye (Lond) , vol.2 , pp. 552-577
    • Sarks, J.P.1    Sarks, S.H.2    Killingsworth, M.C.3
  • 44
    • 84917036192 scopus 로고    scopus 로고
    • Bressler SB, Bressler NM, Sarks S, Sarks J. Age-related macular degeneration: nonneovascular early AMD, intermediate AMD, and geographic atrophy. In: Ryan SJ, Schachat AP, eds. Retina. Philadelphia: Elsevier Mosby; 2006:1041-1074.
    • Bressler SB, Bressler NM, Sarks S, Sarks J. Age-related macular degeneration: nonneovascular early AMD, intermediate AMD, and geographic atrophy. In: Ryan SJ, Schachat AP, eds. Retina. Philadelphia: Elsevier Mosby; 2006:1041-1074.
  • 46
    • 34447631882 scopus 로고    scopus 로고
    • Age-related changes in human macular Bruch's membrane as seen by quick-freeze/deep-etch
    • Huang JD, Presley JB, Chimento MF, Curcio CA, Johnson M. Age-related changes in human macular Bruch's membrane as seen by quick-freeze/deep-etch. Exp Eye Res. 2007;85:202-218.
    • (2007) Exp Eye Res , vol.85 , pp. 202-218
    • Huang, J.D.1    Presley, J.B.2    Chimento, M.F.3    Curcio, C.A.4    Johnson, M.5
  • 48
    • 0031050490 scopus 로고    scopus 로고
    • Characteristics of Drusen and Bruch's membrane in postmortem eyes with age-related macular degeneration
    • Spraul CW, Grossniklaus HE. Characteristics of Drusen and Bruch's membrane in postmortem eyes with age-related macular degeneration. Arch Ophthalmol. 1997;115:267-273.
    • (1997) Arch Ophthalmol , vol.115 , pp. 267-273
    • Spraul, C.W.1    Grossniklaus, H.E.2
  • 49
    • 0028233212 scopus 로고
    • Clinicopathologic correlation of drusen and retinal pigment epithelial abnormalities in age-related macular degeneration
    • Bressler NM, Silva JC, Bressler SB, Fine SL, Green WR. Clinicopathologic correlation of drusen and retinal pigment epithelial abnormalities in age-related macular degeneration. Retina. 1994;14:130-142.
    • (1994) Retina , vol.14 , pp. 130-142
    • Bressler, N.M.1    Silva, J.C.2    Bressler, S.B.3    Fine, S.L.4    Green, W.R.5
  • 50
    • 0020071301 scopus 로고
    • Drusen patterns predisposing to geographic atrophy of the retinal pigment epithelium
    • Sarks SH. Drusen patterns predisposing to geographic atrophy of the retinal pigment epithelium. Aust J Ophthalmol. 1982;10:91-97.
    • (1982) Aust J Ophthalmol , vol.10 , pp. 91-97
    • Sarks, S.H.1
  • 51
    • 0022642121 scopus 로고
    • Clinicopathologic correlation of lipidization and detachment of the retinal pigment epithelium
    • el Baba F, Green WR, Fleischmann J, Finkelstein D, de la Cruz ZC. Clinicopathologic correlation of lipidization and detachment of the retinal pigment epithelium. Am J Ophthalmol. 1986;101:576-583.
    • (1986) Am J Ophthalmol , vol.101 , pp. 576-583
    • el Baba, F.1    Green, W.R.2    Fleischmann, J.3    Finkelstein, D.4    de la Cruz, Z.C.5
  • 53
    • 0344791691 scopus 로고    scopus 로고
    • Basal linear deposit and large drusen are specific for early age-related maculopathy
    • Curcio CA, Millican CL. Basal linear deposit and large drusen are specific for early age-related maculopathy. Arch Ophthalmol. 1999;117:329-339.
    • (1999) Arch Ophthalmol , vol.117 , pp. 329-339
    • Curcio, C.A.1    Millican, C.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.