Promyelocytic leukemia nuclear bodies provide a scaffold for human polyomavirus JC replication and are disrupted after development of viral inclusions in progressive multifocal leukoencephalopathy

Journal of Neuropathology and Experimental Neurology

Volumn 67, Issue 4, 2008, Pages 299-308

  Shishido Hara, Yukiko ^a,b   Higuchi, Kayoko ^c   Ohara, Sinji ^d   Duyckaerts, Charles ^e   Hauw, Jean Jacques ^e   Uchihara, Toshiki ^a  

^a TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^b KYORIN UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c Aizawa Hospital   (Japan)

^d National Hospital Organization Matsumoto Medical Center Matsumoto Hospital   (Japan)

^e PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

JC virus; Progressive multifocal leukoencephalopathy; Promyelocytic leukemia nuclear bodies; Sp100; SUMO 1; Ubiquitin

Indexed keywords

CYCLINE; GENOMIC DNA; PROMYELOCYTIC LEUKEMIA PROTEIN; SUMO 1 PROTEIN; UBIQUITIN; VIRUS CAPSID ANTIGEN; VIRUS DNA;

ADULT; AGED; ARTICLE; CADAVER; CELL DEGENERATION; CELL NUCLEUS; CELL NUCLEUS INCLUSION BODY; CLINICAL ARTICLE; CONTROLLED STUDY; DNA REPLICATION; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN SITU HYBRIDIZATION; INTRANUCLEAR SPACE; JC VIRUS; MALE; MOLECULE; OLIGODENDROGLIA; PRIORITY JOURNAL; PROGENY; PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY; PROMYELOCYTIC LEUKEMIA; PROTEIN ASSEMBLY; VIRUS CAPSID; VIRUS INCLUSION; VIRUS INHIBITION; VIRUS REPLICATION;

ADULT; AGED; AGED, 80 AND OVER; ANIMALS; CAPSID PROTEINS; CERCOPITHECUS AETHIOPS; COS CELLS; FEMALE; HUMANS; INCLUSION BODIES, VIRAL; JC VIRUS; LEUKOENCEPHALOPATHY, PROGRESSIVE MULTIFOCAL; MALE; MICROSCOPY, ELECTRON, TRANSMISSION; MIDDLE AGED; NEOPLASM PROTEINS; NUCLEAR PROTEINS; SUMO-1 PROTEIN; TRANSCRIPTION FACTORS; TRANSFECTION; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN; VIRUS REPLICATION;

EID: 41949090887     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1097/NEN.0b013e31816a1dd3     Document Type: Article

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