Structural considerations for designing adenosine analogs as selective inhibitors of Trichomonas sp. glyceraldehyde-3-phosphate dehydrogenase

In Silico Biology

Volumn 7, Issue 6, 2007, Pages 583-593

  Kundu, Sangeeta ^a   Roy, Debjani ^a  

^a BOSE INSTITUTE   (India)

Author keywords

Docking; Drug design; Glyceraldehyde 3 phosphate dehydrogenase; Homology modeling; Trichomonas vaginalis

Indexed keywords

2' DEOXY 2' (3 METHOXYBENZAMIDO)ADENOSINE; 2' DEOXY 2' (3,5 DI METHOXYBENZAMIDO)ADENOSINE; 6 N BENZYLADENOSINE; ADENOSINE; ADENOSINE DERIVATIVE; DIMER; ENZYME INHIBITOR; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE INHIBITOR; N 6 (1 BENZYLMETHYL) 2' DEOXY 2' (3 METHOXYBENZAMIDO)ADENOSINE; N 6 (1 BENZYLMETHYL)ADENOSINE; N 6 (1,2,3,4 TETRAHYDRONAPHTHYL) 2' DEOXY 2' (3,5 DIMETHOXYBENZAMIDO)ADENOSINE; N 6 BENZYL 2' DEOXY 2' (3,5 DI METHOXYBENZAMIDO)ADENOSINE; N 6 NAPHTHALENEADENOSINE; NICOTINAMIDE ADENINE DINUCLEOTIDE; RIBOSE; UNCLASSIFIED DRUG;

ARTICLE; BINDING KINETICS; CITRIC ACID CYCLE; CRYSTAL STRUCTURE; DRUG DESIGN; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG TARGETING; GLYCOLYSIS; HUMAN; HYDROPHOBICITY; LIVER; MOLECULAR DOCKING; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; NUCLEOTIDE SEQUENCE; TRICHOMONAS VAGINALIS;

ADENOSINE; AMINO ACID SEQUENCE; ANIMALS; ANTITRICHOMONAL AGENTS; BINDING SITES; DRUG DESIGN; ENZYME INHIBITORS; GLUCOSEPHOSPHATE DEHYDROGENASE; HUMANS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; TRICHOMONAS;

EID: 41849146017     PISSN: 13866338     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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