메뉴 건너뛰기




Volumn 56, Issue 6, 2008, Pages 1896-1906

Influence of alternative liquid chromatography techniques on the chemical complexity and bioactivity of isolated proanthocyanidin mixtures

Author keywords

Proanthocyanidins; Sephadex LH 20; Silica gel type G; Topoisomerase II bioassay; Toyopearl HW 40; Vaccinium angustifolium Ait.; Wild blueberry

Indexed keywords

DNA TOPOISOMERASE (ATP HYDROLYSING); ENZYME INHIBITOR; PLANT EXTRACT; PROANTHOCYANIDIN;

EID: 41849137615     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf073001k     Document Type: Article
Times cited : (13)

References (55)
  • 1
    • 0345215163 scopus 로고    scopus 로고
    • Protective effect of grape seed proanthocyanidins and selected antioxidants against TPA-induced hepatic and brain lipid peroxidation and DNA fragmentation, and peritoneal macrophage activation in mice
    • Bagchi, D.; Garg, A.; Krohn, R. L.; Bagchi, M.; Bagchi, D. J.; Balmoori, J.; Stohs, S. J. Protective effect of grape seed proanthocyanidins and selected antioxidants against TPA-induced hepatic and brain lipid peroxidation and DNA fragmentation, and peritoneal macrophage activation in mice. Gen. Pharmacol. 1998, 30, 771-776.
    • (1998) Gen. Pharmacol , vol.30 , pp. 771-776
    • Bagchi, D.1    Garg, A.2    Krohn, R.L.3    Bagchi, M.4    Bagchi, D.J.5    Balmoori, J.6    Stohs, S.J.7
  • 2
    • 0035022276 scopus 로고    scopus 로고
    • Red wine, dealcoholized red wine, and especially grape juice inhibit atherosclerosis in a hamster model
    • Vinson, J. A.; Tuefel, K.; Wu, N. Red wine, dealcoholized red wine, and especially grape juice inhibit atherosclerosis in a hamster model. Atherosclerosis 2001, 156, 67-72.
    • (2001) Atherosclerosis , vol.156 , pp. 67-72
    • Vinson, J.A.1    Tuefel, K.2    Wu, N.3
  • 3
    • 34447634492 scopus 로고    scopus 로고
    • Antibacterial properties and major bioactive components of cinnamon stick (Cinnamomum burmannii): Activity against food borne pathogenic bacteria
    • Shan, B.; Cai, Y. Z.; Brooks, J. D.; Corke, H. Antibacterial properties and major bioactive components of cinnamon stick (Cinnamomum burmannii): activity against food borne pathogenic bacteria. J. Agric. Food Chem. 2007, 55, 5484-90.
    • (2007) J. Agric. Food Chem , vol.55 , pp. 5484-5490
    • Shan, B.1    Cai, Y.Z.2    Brooks, J.D.3    Corke, H.4
  • 4
    • 34447515810 scopus 로고    scopus 로고
    • Cranberry and blueberry: Evidence for protective effects against cancer and vascular diseases
    • Neto, C. C. Cranberry and blueberry: evidence for protective effects against cancer and vascular diseases. Mol. Nutr. Food Res. 2007, 51, 652-664.
    • (2007) Mol. Nutr. Food Res , vol.51 , pp. 652-664
    • Neto, C.C.1
  • 5
    • 0034519572 scopus 로고    scopus 로고
    • Isolation and characterization of endothelium-dependent vasorelaxing compounds from grape seeds
    • Fitzpatrick, D. F.; Fleming, R. C.; Bing, B.; Maggi, D. A.; O'Malley, R. M. Isolation and characterization of endothelium-dependent vasorelaxing compounds from grape seeds. J. Agric. Food Chem. 2000, 48, 6384-6390.
    • (2000) J. Agric. Food Chem , vol.48 , pp. 6384-6390
    • Fitzpatrick, D.F.1    Fleming, R.C.2    Bing, B.3    Maggi, D.A.4    O'Malley, R.M.5
  • 6
    • 25444490122 scopus 로고    scopus 로고
    • Phenolic compounds from blueberries can inhibit colon cancer cell proliferation and induce apoptosis
    • Yi, W.; Fischer, J.; Krewer, G.; Akoh, C C Phenolic compounds from blueberries can inhibit colon cancer cell proliferation and induce apoptosis. J. Agric. Food Chem. 2005, 53, 7320-7329.
    • (2005) J. Agric. Food Chem , vol.53 , pp. 7320-7329
    • Yi, W.1    Fischer, J.2    Krewer, G.3    Akoh, C.C.4
  • 9
    • 23844526357 scopus 로고    scopus 로고
    • Anticancer effects of oligomeric proanthocyanidins on human colorectal cancer cell line, SNU-C4
    • Kim, Y.; Park, H.; Yoon, S.; Kim, M.; Leem, K.; Chung, J.; Kim, H. Anticancer effects of oligomeric proanthocyanidins on human colorectal cancer cell line, SNU-C4. World J. Gastroenterol. 2005, 11, 4674-4678.
    • (2005) World J. Gastroenterol , vol.11 , pp. 4674-4678
    • Kim, Y.1    Park, H.2    Yoon, S.3    Kim, M.4    Leem, K.5    Chung, J.6    Kim, H.7
  • 10
    • 0037168947 scopus 로고    scopus 로고
    • Flavanols and procyanidins of cocoa and chocolate inhibit growth and polyamine biosynthesis of human colonic cancer cells
    • Carnesecchi, S.; Schneider, Y.; Lazarus, A. S.; Coehlo, D.; Gosse, F.; Raul, F. Flavanols and procyanidins of cocoa and chocolate inhibit growth and polyamine biosynthesis of human colonic cancer cells. Cancer Lett. 2002, 175, 147-155.
    • (2002) Cancer Lett , vol.175 , pp. 147-155
    • Carnesecchi, S.1    Schneider, Y.2    Lazarus, A.S.3    Coehlo, D.4    Gosse, F.5    Raul, F.6
  • 11
    • 0034657286 scopus 로고    scopus 로고
    • Proanthocyanidins and tannin-like compounds - nature, occurrence, dietary intake, and effects on nutrition and health
    • Santos-Buelga, C.; Scalbert, A. Proanthocyanidins and tannin-like compounds - nature, occurrence, dietary intake, and effects on nutrition and health. J. Sci. Food Agric. 2000, 80, 1094-1117.
    • (2000) J. Sci. Food Agric , vol.80 , pp. 1094-1117
    • Santos-Buelga, C.1    Scalbert, A.2
  • 12
    • 33846798034 scopus 로고    scopus 로고
    • Immune effects of cocoa procyanidin oligomers on peripheral blood mononuclear cells
    • Kenny, T. P.; Keen, C. L.; Schmitz, H. H.; Gershwin, M. E. Immune effects of cocoa procyanidin oligomers on peripheral blood mononuclear cells. Exp. Biol. Med. 2007, 232, 293-300.
    • (2007) Exp. Biol. Med , vol.232 , pp. 293-300
    • Kenny, T.P.1    Keen, C.L.2    Schmitz, H.H.3    Gershwin, M.E.4
  • 13
    • 0001585772 scopus 로고    scopus 로고
    • The structure of cranberry proanthocyanidins which inhibit adherence of uropathogenic P-fimbriated Escherichia coli in vitro
    • Foo, L. Y.; Lu, Y.; Howell, A. B.; Vorsa, N. The structure of cranberry proanthocyanidins which inhibit adherence of uropathogenic P-fimbriated Escherichia coli in vitro. Photochemistry 2000, 54, 173-181.
    • (2000) Photochemistry , vol.54 , pp. 173-181
    • Foo, L.Y.1    Lu, Y.2    Howell, A.B.3    Vorsa, N.4
  • 14
    • 0033802087 scopus 로고    scopus 로고
    • A-type proanthocyanidin trimers from cranberry that inhibit adherence of uropathogenic P-fimbriated Escherichia coli in vitro
    • Foo, L. Y.; Lu, Y.; Howell, A. B.; Vorsa, N. A-type proanthocyanidin trimers from cranberry that inhibit adherence of uropathogenic P-fimbriated Escherichia coli in vitro. J. Nat. Prod. 2000, 63, 1225-1228.
    • (2000) J. Nat. Prod , vol.63 , pp. 1225-1228
    • Foo, L.Y.1    Lu, Y.2    Howell, A.B.3    Vorsa, N.4
  • 15
    • 6344278620 scopus 로고    scopus 로고
    • Effective separation of potent antiproliferation and antiadhesion components from wild blueberry (Vaccinium angustifolium Ait.) fruits
    • Schmidt, B. M.; Howell, A. B.; McEniry, B.; Knight, C. T.; Seigler, D.; Erdman, J. W., Jr.; Lila, M. A. Effective separation of potent antiproliferation and antiadhesion components from wild blueberry (Vaccinium angustifolium Ait.) fruits. J. Agric. Food Chem. 2004, 52, 6433-6442.
    • (2004) J. Agric. Food Chem , vol.52 , pp. 6433-6442
    • Schmidt, B.M.1    Howell, A.B.2    McEniry, B.3    Knight, C.T.4    Seigler, D.5    Erdman Jr., J.W.6    Lila, M.A.7
  • 17
    • 0042261671 scopus 로고    scopus 로고
    • Antioxidant protection of low density lipoprotein by procyanidins: Structure/activity relationships
    • da Silva Porto, P. A. L.; Laranjinha, J. A. N.; de Freitas, V. A. P. Antioxidant protection of low density lipoprotein by procyanidins: structure/activity relationships. Biochem. Pharmacol. 2003, 66, 947-954.
    • (2003) Biochem. Pharmacol , vol.66 , pp. 947-954
    • da Silva Porto, P.A.L.1    Laranjinha, J.A.N.2    de Freitas, V.A.P.3
  • 18
    • 24344443633 scopus 로고    scopus 로고
    • Occurrence and biological significance of proanthocyanidins in the American diet
    • Prior, R. L.; Gu, L. Occurrence and biological significance of proanthocyanidins in the American diet. Phytochemistry 2005, 66, 2264-2280.
    • (2005) Phytochemistry , vol.66 , pp. 2264-2280
    • Prior, R.L.1    Gu, L.2
  • 19
    • 33750608363 scopus 로고    scopus 로고
    • Significance of sample preparation in developing analytical methodologies for accurate estimation of bioactive compounds in functional foods
    • Luthria, D. Significance of sample preparation in developing analytical methodologies for accurate estimation of bioactive compounds in functional foods. J. Sci. Food Agric. 2006, 86, 2266-2272.
    • (2006) J. Sci. Food Agric , vol.86 , pp. 2266-2272
    • Luthria, D.1
  • 20
    • 31044449048 scopus 로고    scopus 로고
    • Influence of sample preparation on assay of phenolic acids from eggplant
    • Luthria, D.; Mukhopadhyay, S. Influence of sample preparation on assay of phenolic acids from eggplant. J. Agric. Food Chem. 2006, 54, 41-47.
    • (2006) J. Agric. Food Chem , vol.54 , pp. 41-47
    • Luthria, D.1    Mukhopadhyay, S.2
  • 21
    • 0034089647 scopus 로고    scopus 로고
    • Anthocyanins, phenolics, and antioxidant capacity of lowbush blueberry products
    • Kalt, W.; McDonald, J. E.; Donner, H. Anthocyanins, phenolics, and antioxidant capacity of lowbush blueberry products. J. Food Sci. 2000, 65, 390-393.
    • (2000) J. Food Sci , vol.65 , pp. 390-393
    • Kalt, W.1    McDonald, J.E.2    Donner, H.3
  • 22
    • 23744451134 scopus 로고    scopus 로고
    • Effects of food processing on blueberry antiproliferation and antioxidant activity
    • Schmidt, B. M.; Erdman, J. W., Jr.; Lila, M. A. Effects of food processing on blueberry antiproliferation and antioxidant activity. J. Food Sci. 2005, 70, S389-394.
    • (2005) J. Food Sci , vol.70
    • Schmidt, B.M.1    Erdman Jr., J.W.2    Lila, M.A.3
  • 23
    • 0028036133 scopus 로고
    • Oligomeric and polymeric proanthocyanidins from grape seeds
    • Prieur, C.; Rigaud, J.; Cheynier, V.; Mountounet, M. Oligomeric and polymeric proanthocyanidins from grape seeds. Phytochemistry 1994, 36, 781-784.
    • (1994) Phytochemistry , vol.36 , pp. 781-784
    • Prieur, C.1    Rigaud, J.2    Cheynier, V.3    Mountounet, M.4
  • 24
    • 0030964063 scopus 로고    scopus 로고
    • Extractable and non-extractable proanthocyanidins in barks
    • Matthews, S.; Mila, I.; Scalbert, A.; Donnelly, D. M. X. Extractable and non-extractable proanthocyanidins in barks. Phytochemistry 1997, 45, 405-410.
    • (1997) Phytochemistry , vol.45 , pp. 405-410
    • Matthews, S.1    Mila, I.2    Scalbert, A.3    Donnelly, D.M.X.4
  • 25
    • 0033004275 scopus 로고    scopus 로고
    • Identification of procyanidins in cocoa (Theobroma cacao) and chocolate using high-performance liquid chromatography mass spectrometry
    • Hammerstone, J. F.; Lazarus, S. A.; Mitchell, A. E.; Rucker, R.; Schmitz, H. H. Identification of procyanidins in cocoa (Theobroma cacao) and chocolate using high-performance liquid chromatography mass spectrometry. J. Agric. Food Chem. 1999, 47, 490-496.
    • (1999) J. Agric. Food Chem , vol.47 , pp. 490-496
    • Hammerstone, J.F.1    Lazarus, S.A.2    Mitchell, A.E.3    Rucker, R.4    Schmitz, H.H.5
  • 26
    • 0037077372 scopus 로고    scopus 로고
    • Fractionation of polymeric procyanidins from lowbush blueberry and quantification of procyanidins in selected foods with and optimized normal-phase HPLC-MS fluorescent detection method
    • Gu, L.; Kelm, M.; Hammerstone, J. F.; Beecher, G.; Cunningham, D.; Vannozzi, S.; Prior, L. Fractionation of polymeric procyanidins from lowbush blueberry and quantification of procyanidins in selected foods with and optimized normal-phase HPLC-MS fluorescent detection method. J. Agric. Food Chem. 2002, 50, 4852-4860.
    • (2002) J. Agric. Food Chem , vol.50 , pp. 4852-4860
    • Gu, L.1    Kelm, M.2    Hammerstone, J.F.3    Beecher, G.4    Cunningham, D.5    Vannozzi, S.6    Prior, L.7
  • 27
    • 33645455557 scopus 로고    scopus 로고
    • High-performance liquid chromatography separation and purification of cacao (Theobroma cacao L.) procyanidins according to degree of polymerization using a diol stationary phase
    • Kelm, M. A.; Johnson, J. C.; Robbins, R. J.; Hammerstone, J. F.; Schmitz, H. H. High-performance liquid chromatography separation and purification of cacao (Theobroma cacao L.) procyanidins according to degree of polymerization using a diol stationary phase. J. Agric. Food Chem. 2006, 54, 1571-6.
    • (2006) J. Agric. Food Chem , vol.54 , pp. 1571-1576
    • Kelm, M.A.1    Johnson, J.C.2    Robbins, R.J.3    Hammerstone, J.F.4    Schmitz, H.H.5
  • 28
    • 0035134932 scopus 로고    scopus 로고
    • Thiolysis-HPLC characterization of apple procyanidins covering a large range of polymerization states
    • Guyot, S.; Mamet, N.; Drilleau, J. Thiolysis-HPLC characterization of apple procyanidins covering a large range of polymerization states. J. Agric. Food Chem. 2001, 49, 14-20.
    • (2001) J. Agric. Food Chem , vol.49 , pp. 14-20
    • Guyot, S.1    Mamet, N.2    Drilleau, J.3
  • 29
    • 0038094483 scopus 로고    scopus 로고
    • Separation of proanthocyanidins by degree of polymerization by means of size-exclusion chromatography and related techniques
    • Yanagida, A.; Shoji, T.; Shibusawa, Y. Separation of proanthocyanidins by degree of polymerization by means of size-exclusion chromatography and related techniques. J. Biochem. Biophys. Methods 2003, 56, 311-322.
    • (2003) J. Biochem. Biophys. Methods , vol.56 , pp. 311-322
    • Yanagida, A.1    Shoji, T.2    Shibusawa, Y.3
  • 31
    • 33749362767 scopus 로고    scopus 로고
    • Analysis of proanthocyanidins and complex polyphenols
    • C. WilliamsonG, Eds, Royal Society of Chemistry: London, U.K
    • Cheynier, V.; Fulcrand, H. Analysis of proanthocyanidins and complex polyphenols. In Methods in Polyphenol Analysis; Santos-Buelga, C. WilliamsonG., Eds.; Royal Society of Chemistry: London, U.K., 2003; pp 282-313.
    • (2003) Methods in Polyphenol Analysis; Santos-Buelga , pp. 282-313
    • Cheynier, V.1    Fulcrand, H.2
  • 32
    • 84985315197 scopus 로고
    • High-pressure liquid chromatography of apple juice phenolics compounds
    • Wilson, E. L. High-pressure liquid chromatography of apple juice phenolics compounds. J. Sci. Food Agric. 1981, 32, 257-264.
    • (1981) J. Sci. Food Agric , vol.32 , pp. 257-264
    • Wilson, E.L.1
  • 33
    • 0000346483 scopus 로고
    • Isolation and determination of polymeric polyphenols using Sephadex LH-20 and analysis of grape tissue extracts
    • Kantz, K.; Singleton, V. L. Isolation and determination of polymeric polyphenols using Sephadex LH-20 and analysis of grape tissue extracts. Am. J. Enol. Vitic. 1990, 41, 223-228.
    • (1990) Am. J. Enol. Vitic , vol.41 , pp. 223-228
    • Kantz, K.1    Singleton, V.L.2
  • 34
    • 0022612150 scopus 로고    scopus 로고
    • Hagerman, A. E.; Klucher, K. M. Tannin-protein interactions. In Plant Flavonoids in Biology and Medicine: Biochemical, Pharmacological, and Structure-Activity Relationships; Alan R. Liss Publishers: New York, 1986.
    • Hagerman, A. E.; Klucher, K. M. Tannin-protein interactions. In Plant Flavonoids in Biology and Medicine: Biochemical, Pharmacological, and Structure-Activity Relationships; Alan R. Liss Publishers: New York, 1986.
  • 35
    • 34548723991 scopus 로고    scopus 로고
    • Reversed-phased HPLC-ESI/MS analysis of birch leaf proanthocyanidins after their acidic degradation in the presence of nucleophiles
    • Karonen, M.; Leikas, A.; Loponen, J.; Sinkkonen, J.; Ossipov, V.; Pihlaja, K. Reversed-phased HPLC-ESI/MS analysis of birch leaf proanthocyanidins after their acidic degradation in the presence of nucleophiles. Phytochem. Anal. 2007, 18, 378-386.
    • (2007) Phytochem. Anal , vol.18 , pp. 378-386
    • Karonen, M.1    Leikas, A.2    Loponen, J.3    Sinkkonen, J.4    Ossipov, V.5    Pihlaja, K.6
  • 37
    • 33750356119 scopus 로고    scopus 로고
    • Isolation and quantification of oligomeric pyranoanthocyanin-flavanol pigments from red wines by combination of column chromatographic techniques
    • He, J.; Santos-Buelga, C.; Mateus, N.; de Freitas, V. Isolation and quantification of oligomeric pyranoanthocyanin-flavanol pigments from red wines by combination of column chromatographic techniques. J. Chromatogr., A 2006, 1134, 215-225.
    • (2006) J. Chromatogr., A , vol.1134 , pp. 215-225
    • He, J.1    Santos-Buelga, C.2    Mateus, N.3    de Freitas, V.4
  • 39
    • 17144465016 scopus 로고    scopus 로고
    • Some potentialities and drawbacks of contempory size-exclusion chromatography
    • Stulik, K.; Pacakova, V.; Ticha, M. Some potentialities and drawbacks of contempory size-exclusion chromatography. J. Biochem. Biophys. Methods 2003, 56, 1-13.
    • (2003) J. Biochem. Biophys. Methods , vol.56 , pp. 1-13
    • Stulik, K.1    Pacakova, V.2    Ticha, M.3
  • 42
    • 33748648670 scopus 로고    scopus 로고
    • Acid-catalyzed rearrangements of flavan-4-phloroglucinol derivatives to novel 6 hydroxyphenyl-6a, 11b-dihydro-6H-[1]benzofuro[2,3- c]-chromenes and hydroxyphenyl-3,29-spirobi [dihydro[1] benzofurans]
    • Steynberg, P. J.; Steynberg, J. P.; Hemingway, R. W.; Ferreira, D.; McGrawc, G. W. Acid-catalyzed rearrangements of flavan-4-phloroglucinol derivatives to novel 6 hydroxyphenyl-6a, 11b-dihydro-6H-[1]benzofuro[2,3- c]-chromenes and hydroxyphenyl-3,29-spirobi [dihydro[1] benzofurans]. J. Chem. Soc., Perkin Trans. 1 1997, 2395-2403.
    • (1997) J. Chem. Soc., Perkin Trans. 1 , pp. 2395-2403
    • Steynberg, P.J.1    Steynberg, J.P.2    Hemingway, R.W.3    Ferreira, D.4    McGrawc, G.W.5
  • 44
    • 1942471903 scopus 로고    scopus 로고
    • A novel DNA topoisomerase inhibitor: Dehydroebriconic acid, one of the lanostane-type triterpene acids from Poria cocos
    • Mizushina, Y.; Akihisa, T.; Ukiya, M.; Murakami, C.; Kuriyama, I.; Xu, X.; Yoshida, H.; Sakaguchi, K. A novel DNA topoisomerase inhibitor: dehydroebriconic acid, one of the lanostane-type triterpene acids from Poria cocos. Cancer Sci. 2004, 95, 354-360.
    • (2004) Cancer Sci , vol.95 , pp. 354-360
    • Mizushina, Y.1    Akihisa, T.2    Ukiya, M.3    Murakami, C.4    Kuriyama, I.5    Xu, X.6    Yoshida, H.7    Sakaguchi, K.8
  • 45
    • 0022896243 scopus 로고
    • Topoisomerase II: A specific marker for cell proliferation
    • Heck, M. M.; Earnshaw, W. C. Topoisomerase II: a specific marker for cell proliferation. J. Cell Biol. 1986, 103, 2569-2581.
    • (1986) J. Cell Biol , vol.103 , pp. 2569-2581
    • Heck, M.M.1    Earnshaw, W.C.2
  • 47
    • 0042513663 scopus 로고    scopus 로고
    • Processing of sorghum (Sorghum bicolor) and sorghum products alters procyanidin oligomer and polymer distribution and content
    • Awika, J. M.; Dykes, L.; Gu, L.; Rooney, L. W.; Prior, R. L. Processing of sorghum (Sorghum bicolor) and sorghum products alters procyanidin oligomer and polymer distribution and content. J. Agric. Food Chem. 2003, 51, 5516-5521.
    • (2003) J. Agric. Food Chem , vol.51 , pp. 5516-5521
    • Awika, J.M.1    Dykes, L.2    Gu, L.3    Rooney, L.W.4    Prior, R.L.5
  • 48
    • 20744452184 scopus 로고    scopus 로고
    • Characterization of polyphenolics in the seed coat of black jamapa bean (Phaseolus vulgaris L)
    • Aparicio-Fernandez, X.; Yousef, G. G.; Loarca-Pina, G.; de Mejia, E.; Lila, M. A. Characterization of polyphenolics in the seed coat of black jamapa bean (Phaseolus vulgaris L). J. Agric. Food Chem. 2005, 53, 4615-4622.
    • (2005) J. Agric. Food Chem , vol.53 , pp. 4615-4622
    • Aparicio-Fernandez, X.1    Yousef, G.G.2    Loarca-Pina, G.3    de Mejia, E.4    Lila, M.A.5
  • 49
    • 0031750423 scopus 로고    scopus 로고
    • LC-UV-electrospray-MS-MS mass spectrometry analysis of plant constituents inhibiting xanthine oxidase
    • Gariboldi, E.; Mascetti, D.; Galli, G.; Caballion, P.; Bosisio, E. LC-UV-electrospray-MS-MS mass spectrometry analysis of plant constituents inhibiting xanthine oxidase. Pharm. Res. 1998, 15, 936-943.
    • (1998) Pharm. Res , vol.15 , pp. 936-943
    • Gariboldi, E.1    Mascetti, D.2    Galli, G.3    Caballion, P.4    Bosisio, E.5
  • 50
    • 0036938075 scopus 로고    scopus 로고
    • Evaluation of the clastogenic, DNA intercalative, and topoisomerase II-interactive properties of bioflavonoids in Chinese hamster V79 cells
    • Snyder, R. D.; Gillies, P. J. Evaluation of the clastogenic, DNA intercalative, and topoisomerase II-interactive properties of bioflavonoids in Chinese hamster V79 cells. Environ. Mol. Mutagen. 2002, 40, 266-276.
    • (2002) Environ. Mol. Mutagen , vol.40 , pp. 266-276
    • Snyder, R.D.1    Gillies, P.J.2
  • 51
    • 0042346439 scopus 로고    scopus 로고
    • Catalytic topoisomerase II inhibitors in cancer therapy
    • Larsen, A. K.; Escargueil, A. E.; Skladanowski, A. Catalytic topoisomerase II inhibitors in cancer therapy. Pharmacol. Ther. 2003, 99, 167-181.
    • (2003) Pharmacol. Ther , vol.99 , pp. 167-181
    • Larsen, A.K.1    Escargueil, A.E.2    Skladanowski, A.3
  • 52
    • 0035663005 scopus 로고    scopus 로고
    • Forum Original Research. Communication transport of proanthocyanidin dimer, trimer, and polymer across monolayers of human intestinal epithelial caco-2 cells
    • Deprez, S.; Mila, I.; Huneau, J. F.; Tome, D.; Scalbert, A. Forum Original Research. Communication transport of proanthocyanidin dimer, trimer, and polymer across monolayers of human intestinal epithelial caco-2 cells. Antioxid. Redox Signal. 2001, 6, 957-967.
    • (2001) Antioxid. Redox Signal , vol.6 , pp. 957-967
    • Deprez, S.1    Mila, I.2    Huneau, J.F.3    Tome, D.4    Scalbert, A.5
  • 53
    • 48749137373 scopus 로고
    • Separation of malt and hop proanthocyanidins on Fractogel TSK HW- 40 (S)
    • Derdelinckx, G.; Jermanis, J. Separation of malt and hop proanthocyanidins on Fractogel TSK HW- 40 (S). J. Chromatogr. 1984, 285, 231-234.
    • (1984) J. Chromatogr , vol.285 , pp. 231-234
    • Derdelinckx, G.1    Jermanis, J.2
  • 54
    • 0032892216 scopus 로고    scopus 로고
    • Isolation and purification of dimeric and trimeric procyanidins from grape seeds
    • Sun, B.; Belchior, G. P.; Ricardo da Silva, J. M.; Spranger, M. I. Isolation and purification of dimeric and trimeric procyanidins from grape seeds. J. Chromatogr., A 1999, 841, 115-121.
    • (1999) J. Chromatogr., A , vol.841 , pp. 115-121
    • Sun, B.1    Belchior, G.P.2    Ricardo da Silva, J.M.3    Spranger, M.I.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.