Neurochemical responses to antidepressants in the prefrontal cortex of mice and their efficacy in preclinical models of anxiety-like and depression-like behavior: A comparative and correlational study

Psychopharmacology

Volumn 197, Issue 4, 2008, Pages 567-580

  Kobayashi, Tomohiro ^a,c   Hayashi, Etsuko ^a   Shimamura, Midori ^a   Kinoshita, Mine ^a   Murphy, Niall P ^b  

^a Development and Medical Affairs Division   (Japan)

^b RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^c TORAY INDUSTRIES INC   (Japan)

Author keywords

Anxiety; Correlation; Depression; Dopamine; Forced swim; Marble burying; Norepinephrine; NRI; Porsolt; Serotonin; SSRI

Indexed keywords

CITALOPRAM; DESIPRAMINE; DOPAMINE; FLUOXETINE; FLUVOXAMINE MALEATE; IMIPRAMINE; NORADRENALIN; SEROTONIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY DISORDER; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATIONAL STUDY; DEPRESSION; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG DOSE INCREASE; DRUG EFFICACY; DRUG MECHANISM; DRUG MEGADOSE; FORCED SWIMMING TEST; LOCOMOTION; LOW DRUG DOSE; MALE; MICRODIALYSIS; MOUSE; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL;

ANIMALS; ANTIDEPRESSIVE AGENTS; ANXIETY; BEHAVIOR, ANIMAL; DEPRESSION; DISEASE MODELS, ANIMAL; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; HELPLESSNESS, LEARNED; MALE; MICE; MOTIVATION; MOTOR ACTIVITY; NEUROTRANSMITTER AGENTS; NOREPINEPHRINE; PREFRONTAL CORTEX; SEROTONIN; STATISTICS AS TOPIC; STEREOTYPED BEHAVIOR; SWIMMING;

EID: 41849123069     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00213-008-1070-6     Document Type: Article

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