Housing and Environment

The Laboratory Rat

Volumn , Issue , 2006, Pages 303-337

  Faith, Robert E ^a   Hessler, Jack R ^b  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 41849117680     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-012074903-4/50013-3     Document Type: Chapter

References (430)

1. Adler M.W., Bendotti C., Ghezzi D., Samanin R., Valzelli L. Morphine analgesia in grouped and isolated rats. Psychopharmacol. 1975, 41:15-18.
2. Aguila H.N., Pakes S.P., Lai W.C., Lu Y.S. The effect of transportation stress on splenic natural killer cell activity in C57BL/6J mice. Lab. anim. Sci. 1988, 38:148-151.
3. Aloisi A.M., Seta D.D., Rendo C., Ceccarelli I., Scaramuzzino A., Farabollini F. Exposure to the estrogen pollutant bisphenol A affects pain behavior induced by subcutaneous formalin injection in male and female rats. Brain Res. 2002, 937:1-7.
4. Akita S., Kawahara M., Takeshita T., Morio T., fujii K. Halothane-induced hepatic microsomal lipid peroxidation in guinea pigs and rats. J. Appl. Toxicol. 1989, 9:9-14.
5. Anthony A. Criteria for acoustics in animal housing. Lab. Anim. Care 1962, 13:340-347.
6. Archana R., Namasivayam A. The effect of acute noise stress on neutrophil functions. Indian J. Physiol. Pharmacol. 1999, 43:491-495.
7. Archana R., Namasivayam A. Acute noise-induced alterations in the immune status of albino rats. Indian J. Physiol. Pharmacol. 2000, 44:105-108.
8. Armario A., Castellanos J.M., Balasch J. Effect of crowding on emotional reactivity in male rats. Nuroendocrin 1984, 39:330-333.
9. Armario A., Castellanos J.M., Balasch J. Adaptation of anterior pituitary hormones to chronic noise stress in male rats. Behav. Neural. Biol. 1984, 41:71-76.
10. Armario A., Ortiz R., Balasch J. Effect of crowding on some physiological and behavioral variables in adult male rats. Physiol. Behav. 1984, 32:35-37.
11. Armario A., Castellanos J.M., Balasch J. Chronic noise stress and insulin secretion in male rats. Physiol. Behav. 1985, 34:359-361.
12. Aston R., Synan J. Chlorine dioxide as a bactericide in waterworks operation. J. N. Eng. Water Works Assoc. 1948, 62:80.
13. Rabinet C. Transgenic mice: an irreplaceable tool for the study of mammalian development and biology. J. Am. Soc. Nephrol. 2000, 11(Suppl 16):88-94.
14. Baker H.J., Lindsey J.R., Weisbroth S.H. Housing to control research variables. The Laboratory Rat 1979, Vol. 1:169-192. Academic Press, New York.
15. Balazs T., Murphy J.B., Grice H.C. The influence of environmental changes on the cardiotoxicity of isoprenaline in rats. J. Pharm. Pharmacol. 1962, 14:750-755.
16. Baldry M.G. The bactericidal, fungicidal and sporicidal properties of hydrogen peroxide and peracetic acid. J. Appl. Bacteriol. 1983, 54:417-423.
17. Ballowitz L. Effects of blue and white light on infant (Gunn) rats and on lactating mother rats. Biol. Neonate 1971, 19:409-425.
18. Banerjee B.D., Koner B.C., Ray A., Pasha S.T. Influence of subchronic exposure to lindane on humoral immunity in mice. Indian J. Exp. Biol. 1996, 34:1109-1113.
19. Banerjee B.D., Pasha S.T., Hussain Q.Z., Koner B.C., Ray A. A comparative evaluation of immunotoxicity of malathion after subchronic exposure in experimental animals. Indian J. Exp. Biol. 1998, 36:273-282.
20. Baran D., Paduraru I., Saramet A., Petrescu E., Haulica I. Influence of light-dark cycle alteration on free radical level in rat cns. Rom. J. Physiol. 2000, 37:23-38.
21. Barrett A.M., Stockham M.A. The effect of housing conditions and simple experimental procedures upon the corticosterone level in the plasma of rats. J. Endocrinol. 1963, 26:97-105.
22. Baudrie V., Laude D., Chaouloff F., Elghozi J.L. Genetic influences on cardiovascular responses to an acoustic startle stimulus in rats. Clin. Exp. Pharmacol. Physiol. 2001, 28:1096-1099.
23. Baumans V., van de Weerd H.A. Enrichment of laboratory animal housing: basic need or luxury?. Scand. Lab. Anim. Sci. 1996, 23(Suppl 1):93-95.
24. Baumel I., de Fao J.J., Lal H. Decreased potency of CNS depressants after prolonged isolation in mice. Psychopharmacol. 1969, 15:153-159.
25. Beall J.R., Torning F.E., Runkle R.S. A laminar flow system for animal maintenance. Lab. Anim. Sci. 1971, 21:206-212.
26. Belanger P.M., Atitse-Gbeassor A. Effect of nonsteroidal anti-inflammatory drugs on the microsomal monooxygenase system of rat liver. Can. J. Physiol. Pharmacol. 1985, 63:798-803.
27. Bellhorn R.W. Lighting in the animal environment. Lab. Anim. Sci. 1980, 30:440-450.
28. Benefiel A.C., Greenough W.T. Effects of experience and environment on the developing and mature brain: implications for laboratory animal housing. ILAR J. 1998, 39:5-11.
29. Bennett E.L., Rosenzweig M.R., Diamond M.C. Rat brain: effects of environmental enrichment on wet and dry weights. Science 1969, 163:825-826.
30. Benson G.K., Morris L.R. Foetal growth and lactation in rats exposed to high temperatures during pregnancy. J. Reprod. Fertil. 1971, 27:369-384.
31. Bernier J., Hugo P., Krzystyniak K., Fournier M. Suppression of humoral immunity in inbred mice by dieldrin. Toxicol. Lett. 1987, 35:231-240.
32. Besch E.L. Animal cage-room dry-bulb and dew-point temperature differentials. ASHRAE 1975, 81:549-557.
33. Blaszezyk J., Tajchert K. Sex and strain differences of acoustic startle reaction development in adolescent albino Wistar and hooded rats. Acta Neurobiol. Exp. 1996, 56:919-925.
34. Blom H.J., Van Tintelen G., Van Vorstenbosch C.J., Baumans V., Beynen A.C. Preferences of mice and rats for types of bedding material. Lab. Anim. 1996, 30:234-244.
35. Bock F.G., Myers H.K., Fox H.W. Cocarcinogenic activity of peroxy compounds. J. Natl. Cancer Inst. 1975, 55:1359-1361.
36. Bomberger C.E., Haar J.L. Restraint and sound strees reduce the in vitro migration of prethymic stem cells to thymus supernatant. Thymus 1992, 19:111-115.
37. Borges J.M., Edward D.P., Tso M.O. A comparative study of photic injury in four inbred strains of albino rats. Curr. Eye Res. 1990, 9:799-803.
38. Borin C., Periquet A., Mitjavila S. Studies on the mechanism of nabam- and zineb-induced inhibition of the hepatic microsomal monooxygenases of the male rat. Toxicol. Appl. Pharmacol. 1985, 81:460-468.
39. Bouchon R., Will B. Effects of post-weaning rearing conditions on learning performance in "dwarf mice". Physiol. Behav. 1982, 28:971-978.
40. Boyle E., Villanueva P.A. Hyperbaric oxygen seizures in rats: effects of handling and chamber noise. Lab. Anim. Sci. 1976, 26:100-101.
41. Brain P., Benton D. The interpretation of physiological correlates of differential housing in laboratory rats. Life Sci. 1979, 24:99-116.
42. Brain P., Benton D. Conditions of housing, hormones, and aggressive behavior. Hormones and Aggressive Behavior 1983, 351-372. Plenum Press, New York. B.B. Svare (Ed.).
43. Brick J.O., Newell R.R., Doherty D.G. A barrier system for a breeding and experimental rodent colony: Description and operation. Lab. anim. Care 1969, 19:93-97.
44. Briel J.E., Kruckenberg S.M., Besch E.L. Observations of Ammonia Generation in Laboratory Animal Quarters. Publication no. 72-03 1972, Institute of Environmental Research, Kansas State University, Manhattan.
45. Broderson J.R., Lindsey J.R., Crawford J.E. The role of environmental ammonia in respiratory mycoplasmosis of rats. Am. J. Pathol. 1976, 85:115-127.
46. Burek J.D., Schwetz B.A. Considerations in the selection and use of chemicals within the animal facility. Lab. Anim. Sci. 1980, 30:414-421.
47. Burkhart C.A., Robinson J.L. High rat pup mortality attributed to the use of cedar-wood shavings as bedding. Lab. Anim. 1978, 12:221-222.
48. Campbell M.A., Gyorkos J., Leece B., Homonko K., Safe S. The effects of twenty-two organochlorine pesticides as inducers of the hepatic drug-metabolizing enzymes. Gen. Pharmacol. 1983, 14:445-454.
49. Carlton B.D., Basaran A.H., Mezza L.E., George E.L., Smith M.K. Reproductive effects in Long-Evans rats exposed to chlorine dioxide. Environ. Res. 1991, 56:170-177.
50. Casale G.P., Cohen S.D., DiCapua R.A. Parathion-induced suppression of humoral immunity in inbred mice. Toxicol. Lett. 1984, 23:239-247.
51. Cass J.S. Chemical factors in laboratory animal surroundings. Bio-Sci 1970, 20:658-662.
52. Chaguri L.C.A.G., Souza N.L., Teixeira M.A., Mori C.M.C., Carissimi A.S., Merusse J.L.B. Evaluation of reproductive indices in rats (Rattus norvegicus) housed under an intracage ventilation system. Contemp. Top. Lab. Anim. Sci. 2001, 40:25-30.
53. Chedid A., Nair V. Diural rhythm in endoplasmic reticulum of rat liver: electron microscopic study. Science 1972, 175:176-179.
54. Christian J.J., LeMunyan C.D. Adverse effects of crowding on lactation and reproduction of mice and two generations of their progeny. Endocrinology 1958, 63:517-529.
55. Christie R.J., Williams F.P., Whitney R.A., Johnson D.J. Techniques used in the establishment and maintenance of a barrier mouse breeding colony. Lab. Anim. Care 1968, 18:544-549.
56. Chvedoff M., Clarke M.R., Irisarri E., Faccini J.M., Monro A.M. Effects of housing conditions on food intake, body weight and spontaneous lesions in mice: a review of the literature and results of an 18-month study. Food Cosmest. Toxicol. 1980, 18:517-522.
57. Cinti H.E., Lemelin M.A., Christian J. Induction of liver microsomal mixed-function oxidases by volatile hydrocarbons. Biochem. Pharmacol. 1976, 25:100-103.
58. Cline J. Gene therapy: current status and future directions. Schweiz Med. Wochenschr. 1986, 116:1459-1464.
59. Clough G. The immediate environment of the laboratory animal. Control of the Animal House Environment 1976, 77-94. Lab. Anim. Ltd., London. T. McSheehy (Ed.).
60. Clough G. Environmental effects on animals used in biomedical research. Biol. Rev. 1982, 57:487-523.
61. Clough G. Environmental factors in relation to the comfort and well-being of laboratory rats and mice. Standards In Laboratory Animal Management: Part 1 1984, 7-24. Universities Federation for animal Welfare, Herfordshire, United Kingdom.
62. Clough G., Wallace J., Gamble M.R., Merryweather E.R., Bailey E. A positive, individually ventilated caging system: a local barrier system to protect both animals and personnel. Lab. Anim. 1995, 29:139-151.
63. Committee to Revise the Guide for the Care and Use of Laboratory Animals Guide for the Care and Use of Laboratory Animals 1996, National Academy Press, Washington, DC.
64. Connelly C.S., Fahl W.E., Iannaccone P.M. The role of transgenic animals in the analysis of various biological aspects of normal and pathologic states. Exp. Cell Res. 1989, 183:257-276.
65. Conney A.H., Burns J.J. Metabolic interactions among environmental chemicals and drugs. Science 1972, 178:576-586.
66. Connolly M.S., Suman M.A., Halberg E., Halberg F. Lighting cycle and social isolation affect development of elevated blood pressure in spontaneously hypertensive rats. Med. Biol. 1983, 61:113-119.
67. Corning B.F., Lipman N.S. A comparison of rodent caging systems based on microenvironmental parameters. Lab. Anim. Sci. 1991, 41:498-503.
68. Corning B.F., Lipman N.S. The effects of a mass air displacement unit on the microenvironmental parameters within isolator cages. Lab. Anim. Sci. 1992, 42:91-93.
69. Cummins R.A., Walsh R.N., Budtz-Olsen O.E., Kontantinos T., Horsfall C.R. Environmentally-enduced changes in the brains of elderly rats. Nature 1973, 243:516-518.
70. Cunliffe-Beamer T.L., Freeman L.C., Myers D.D. Barbiturate sleeptime in mice exposed to autoclaved or unautoclaved wood beddings. Lab. Anim. Sci. 1981, 31:672-675.
71. Cunliffe-Beamer T.L., Les E.P. Effectiveness of pressurized individually ventilated (PIV) cages in reducing transmission of pneumonia virus of mice (PVM). Lab. Anim. Sci. 1983, 33:495.
72. Dairman W., Balazs T. Comparison of liver microsome enzyme systems and barbiturate sleep times in rats caged individually or communally. Biochem. Pharmacol. 1970, 19:951-955.
73. Dale O., Nilsen O.G. Glutathione and glutathione S-transferases in rat liver after inhalation of halothane and enflurane. Toxicol. Lett. 1984, 23:61-66.
74. Dale O., Nielsen K., Westgaard G., Nilsen O.G. Drug metabolizing enzymes in the rat after inhalation of halothane and enflurane: different pattern of response in liver, kidney and lung and possible implications for toxicity. Br. J. Anaesth. 1983, 55:1217-1224.
75. Dalhamn T. Mucous flow and ciliary activity in the trachea of healthy rats and rats exposed to respiratory irritant gases. Acta Physiol. Sci 1956, 36(Suppl 123):1-158.
76. Dalvi R.R., Terse P.S. Induction of hepatic microsomal drug metabolizing enzyme system by levamisole in male rats. J. Pharm. Pharmacol. 1990, 42:58-59.
77. Damon E.G., Eidson A.F., Hahn F.F. Acute uranium toxicity resulting from subcutaneous implantation of soluble yellow-cake powder in Fischer-344 rats. NUREG/CR-2539, LMF-94, Springfield, VA 1982, 32-37.
78. Damon E.G., Eidson A.F., Hobbs C.H., Hahn F.F. Effect of acclimation to caging on nephrotoxic response of rats to uranium. Lab. Anim. Sci. 1986, 36:24-27.
79. Daniel W., Friebertshauser J., Steffen C. The effect of imipramine and desipramine on mixed function oxidase in rats. Naunyn Schmiedebergs Arch. Pharmacol. 1984, 328:83-86.
80. Davis D.E. Social behavior in a laboratory environment. Laboratory Animal Housing 1978, 44-63. Institute of Laboratory Animal Resoures, National Academy of Science, Washington, DC.
81. Degen G.H., Bolt H.M. Endocrine disruptors: update on xenoestrogens. Int. Arch Occup. Environ. Health 2000, 73:433-441.
82. Depocas F. The calorigenic response of cold-acclimated white rats to infused nor-adrenalin. Canadian J. Biochem. Physiol. 1960, 38:107-114.
83. Dessi-Fulgheri F., Porrini S., Farabollini F. Effects of perinatal exposure to bisphenol A on play behavior of female and male juvenile rats. Environ. Health Persp. 2002, 110(Suppl 3):403-407.
84. Douglas G.R., Nestmann E.R., Lebel G. Contribution of chlorination to the mutagenic activity of drinking water extract in Salmonella and Chinese hamster ovary cells. Environ. Health Perspect. 1986, 69:81-87.
85. Drozdowicz C.K., Bowman T.a., Webb M.L., Lang C.M. Effect on in-house transport on murine plasma corticosterone concentration and blood lymphocyte populations. Am. J. Vet. Res. 1990, 51:1841-1846.
86. Duke J.L., Zammit T.G., Lawson D.M. The effects of routine cage-changing on cardiovasclar and behavioral parameters in male Sprague-Dawley rats. Contemp. Top. Lab. Anim. Sci. 2001, 40:17-20.
87. Dymsza H.A., Miller S.A., Maloney J.F., Foster H.L. Equilibration of the laboratory rat following exposure to shipping stresses. Lab. Anim. Care 1963, 13:60-65.
88. Einon D., Stewart J., Atkinson S., Morgan M. Effect of isolation on barbiturate anesthesia in the rat. Psychopharmacol. 1976, 50:85-88.
89. Elenkov I.J., Chrousos G.P. Stress, cytokine patterns and susceptibility to disease. Baillieres Best Pract. Res. Clin. Endocrinol. Metab. 1999, 13:583-595.
90. Elenkov I.J., Webster E.L., Torpy D.J., Chrousos G.P. Stress, corticotrophin-releasing hormone, glucocorticoids, and the immune/inflammatory response: acute and chronic effects. Ann. NY Acad. Sci. 1999, 876:1-11.
91. Ema M., Fujii S., Furukawa M., Kiguchi M., Ikka T., Harazono A. Rat two-generation reproductive toxicity study of bisphenol A. Reprod. Toxicol. 2001, 15:505-523.
92. Erickson R.P. Antisense transgenics in animals. Methods 1999, 18:304-310.
93. Evans M.J. Potential for generic manipulation of mammals. Mol. Biol. Med. 1989, 6:557-565.
94. Everitt J.I., Paul W.R., Davis T.W. Urologic syndrome associated with wire caging in AKR mice. Lab. Anim. Sci. 1988, 38:609-611.
95. Faith R.E., Henning S.J., McCarty D.R., McKenzie W.F. Reduction of reproductive efficiency in Sprague-Dawley rats by soft wood bedding. Lab. Anim. Sci. 1985, 35:555.
96. Farabollini F., Porrini S., Dessi-Fulgheri F. Perinatal exposure to the estrogenic pollutant bisphenol A affects behavior in male and female rats. Pharmacol. Biochem. Behav. 1999, 64:687-694.
97. Farabollini F., Porrini S., Seta D.D., Bianchi F., Dessi-Fulgheri F. Effects of perinatal exposure to bisphenol A on sociosexual behavior of female and male rats. Environ. Health Persp. 2002, 110(Suppl 3):409-414.
98. Faraday M.M. Rat sex and strain differences in responses to stress. Physiol. Behav. 2002, 75:507-522.
99. Fauci A.S. Clinical aspects of immunosuppression: use of cytotoxic agents and corticosteroids. Immunology III 1985, 546-557. W.B. Saudners, Philadelphia. J.A. Bellanti (Ed.).
100. Feldman D., Krishnan A. Estrogens in unexpected places: possible implications for researchers and consumers. Environ. Health Perspect. 1995, 103(Suppl 7):129-133.
101. Feldman D. Rodent allergens and occupational health programs in research facilities: the complexity of political and immune responses. Contemp. Topics Lab. Anim. Sci. 2003, 42:144-147.
102. Fenner-Crisp P.A. Endocrine modulators: risk characterization and assessment. Toxicol. Pathol. 2000, 28:438-440.
103. Ferstrom J.D., Wurtman R.J. Brain serotonin content: physiological dependence on plasma tryptophan levels. Science 1971, 173:149.
104. Fidler I.J. Depression of macrophages in mice drinking hyperchlorinated water. Nature 1977, 270:735-736.
105. File S.E. Exploration, distraction and habituation in rats, reared in isolation. Dev. Psychobiol. 1978, 11:73-81.
106. Fletcher J.I. Influence of noise on animals. Control of the Animal House Environment 1976, 51-62. Laboratory Animal Limited, London. T. McSheehy (Ed.).
107. Flynn R.J. A new cage cover as an aid to laboratory rodent disease control. Proc. Soc. Exp. Biol. Med. 1968, 129:714-717.
108. Flynn R.J., Poole C.M., Tyler S.A. Long distance air transport of aged laboratory mice. J. Gerontol. 1971, 26:201-203.
109. Foley K.M. A comparison of the pesticide residues in corn cob and wood beddings. Abstr. 22. 29th Annual Session 1979.
110. Foster C.H.L., Trexler P.C., Rumsey G. A canned sterile shipping diet for small laboratory rodents. Lab. Anim. Care 1967, 17:400-405.
111. Foster H.L. Large scale production of rats free of commonly occurring pathogens and parasites. Proc. Anim. Care Panel 1958, 8:92-100.
112. Foster H.L. Establishment and operation of SPF colonies. Problems of Laboratory Animal Disease 1962, 249-259. Academic Press, New York. R.J.C. Harris (Ed.).
113. Foster H.L., Pfan E.S. Gnotobiotic animal production at the Charles River Breeding Laboratories, Inc. Lab. Anim. Care 1963, 13:609-632.
114. Foster H.L., Foster S.J., Pfan E.S. The large scale production of caesarian originated barrier sustained mice. Lab. Anim. Care 1963, 13:711-718.
115. Fouts J.R. Some effects of insecticides on hepatic microsomal enzymes in various animal species. Rev. Can. Biol. 1970, 29:377-389.
116. Fouts J.R. Overview of the field: environmental factors affecting chemical or drug effects in animals. Fed. Proc. Fed. Am. Soc. Exp. Biol. 1976, 35:1162-1165.
117. Friedman M., Byers S.O., Brown A.E. Plasma lipid responses of rats and rabbits to an auditory stimulus. Am. J. Physiol 1967, 212:1174-1178.
118. Fritz T.E., Tolle D.V., Flynn R.J. Hemorrhagic diathesis in laboratory rodents. Proc. Soc. Exp. Biol. Med. 1968, 128:228-234.
119. 9-tetrahydrocannibol. Physiol. Behav. 1978, 21:581-585.
120. 9-tetrehydrocannabinol and its characteristics. Physiol. Behav. 1979, 22:535-540.
121. Fullerton P.M., Gilliatt R.W. Pressure neuropathy in the hind foot of the guinea pig. J. Neurol. Neurosurg. Psychiatry 1967, 30:18-25.
122. Gamble M.R. Fire alarms and oestrus in rats. Lab. Anim. 1976, 10:161-163.
123. Gamble M.R., Clough G. Ammonia build-up in animal boxes and its effect on rat tracheal epithelium. Lab. Anim. 1976, 10:93-104.
124. Gao H., Zhang S.Z. Effect of noise on blood pressure of various types of rats. Zhonghua Yu Fang Yi Xue Za Zhi 1992, 26:275-277.
125. Gardiner S.M., Bennet T. The effects of short-term isolation on systolic blood pressure and heart rate in rats. Med. Biol. 1977, 55:325-329.
126. Gartner K., Buttner D., Dohler B.K., Friedel R., Lindena J., Trautschold I. Stress response of rats to handling and experimental procedures. Lab. Anim. 1980, 14:267-274.
127. Geber W.F., Anderson T.A., Van Dyne V. Physiologic responses of the albino rat to chronic noise stress. Arch. Environ. Health 1966, 12:751-754.
128. Gelineo S. Influence du milieu thermique d'adaptation sur la thermogenese des homeothermes. Annales de Physiologie et de Physiocochimie Biologique 1934, 10:1083-1115.
129. Gentsch C., Lichtsteiner M., Feer H. Locomotor activity, defecation score and corticosterone levels during an open field exposure: a comparison among individually and group housed rats and genetically selected rat lines. Physiol. Behav. 1981, 27:183-186.
130. Gerges S.E., Abdel-Rahman M.S., Skowronski G.A., Von Hagen S. Effects of Alcide gel on fetal development in rats and mice. II. J. Appl. Toxicol. 1985, 5:104-109.
131. Gesi M., Fornai F., Lenzi P., Natale G., Soldani P., Paparelli A. Time-dependent changes in adrenal cortex ultrastructure and corticosterone levels after noise exposure in male rats. Eur. J. Morphol. 2001, 39:129-135.
132. Gesi M., Lenzi P., Alessandri M.G., Ferrucci M., Fornai F., Paparelli A. Brief and repeated noise exposure produces different morphological and biochemical effects in noradrenaline and adrenaline cells of adrenal medulla. J. Anat. 2002, 200:159-168.
133. Gibson S.V., Besch-Williford C., Raisbeck M.F., Wagner J.E., McLaughlin R.M. Organophosphate toxicity in rats associated with contaminated bedding. Lab. Anim. Sci. 1987, 37:59-62.
134. Glowa J.R., Hansen C.T. Differences in response to an acoustic startle stimulus among 46 rat strains. Behav. Genet. 1994, 24:79-84.
135. Golberg L. Carcinogenesis Testing of Chemicals 1974, CRC Press, Cleveland, OH.
136. Goldstein D. Convulsions elicited by handling: a sensitive method of measuring CNS excitation in mice treated with reserpine or convulsant drugs. Psychopharm. 1973, 32:27-32.
137. Gomella C., Musquere P. Disinfection of water by chlorine, ozone, and chlorine dioxide. Int. Water Supply Assoc., Congr. [Proc.] 1980, 13:k1-k12.
138. Gordon A.H., D'Arcy Hart P., Young M.R. Ammonia inhibits phagosome-lysosome fusion in macrophages. Nature 1980, 286:79-80.
139. Gordon J.W. Studies of foreign genes transmitted through the germ limes of transgenic mice. J. Exp. Zool. 1983, 228:313-324.
140. Gordon J.W., Ruddle F.H. DNA-mediated genetic transformation of mouse embryos and bone marrow: a review. Gene 1985, 33:121-136.
141. Gordon S., Wallace J., Cook A., Tee R.D., Newman-Taylor A.J. Reduction of exposure to laboratory animal allergens in the workplace. Clin. Exp. Allergy 1997, 27:744-751.
142. Govindwar S.P., Siddiqui A.M., Hashmi R.S., Kachole M.S., Pawar S.S. Effect of ampicillin on hepatic microsomal mixed-function oxidase system in male rats. Toxicol. Lett 1984, 23:201-204.
143. Grant L., Hopkinson P., Jennings G., Jenner F.A. Period of adjustment of rats used for experimental studies. Nature 1971, 232:135.
144. Gray L.E., Kelce W.R. Latent effects of pesticides and toxic substances on sexual differentiation of rodents. Toxicol. Ind. Health 1996, 12:515-531.
145. Gray L.E., Ostby J. Effects of pesticides and toxic substances on behavioral and morphological reproductive development: endocrine versus nonendocrine mechanisms. Toxicol. Ind. Health 1998, 14:159-184.
146. Gray L.E., Ostby J.S., Kelce W.R. Developmental effects of an environmental antiandrogen: the fungicide vinclozolin alters sex differentiation of the male rat. Toxicol. Appl. Pharmacol. 1994, 129:46-52.
147. Grewal I.S., Heilig M., Miller A., Sercarz E.E. Environmental regulation of T-cell function in mice: group housing of males affects accessory cell function. Immunol 1997, 90:165-168.
148. Grewal I.S., Miller A., Sercarz E.E. The influence of mouse housing density on autoimmune reactivity. Autoimmunity 1997, 26:209-214.
149. Grover-Johnson N., Spencer P.S. Peripheral nerve abnor-malities in aging rats. J. Neuropath. Exp. Neurol. 1981, 40:155-165.
150. Guide for the Care and Use of Laboratory Animals 1996, National academy Press, Washington, DC.
151. Gwosdow A.R., Besch E.L. Effect of thermal history on the rat's response to varying environmental temperature. J. Appl. Physiol. 1985, 59:413-419.
152. Haake J., Kelley M., Keys B., Safe S. The effects of organochlorine pesticides as inducers of testosterone and benzo [a] pyrene hydroxylases. Gen. Pharmacol. 1987, 18:165-169.
153. Hall F.S. Social deprivation of neonatal, adolescent, and adult rats has distinct neurochemical and behavioral consequences. Crit. Rev. Neurobiol. 1998, 12:129-162.
154. Hallback M. Consequence of social isolation on blood pressure, cardiovascular reactivity and design in spontaneously hypertensive rats. Acta Physiol. Scand. 1975, 93:455-465.
155. Hamilton B.A., Frankel W.N. Of mice and genome sequence. Cell 2001, 107:13-16.
156. Goodman and Gilman's: the Pharmacological Basis of Therapeutics 2001, McGraw-Hill, New York. J.G. Hardman, L.E. Limbird, A.G. Gilman (Eds.).
157. 2 on the absorption and distribution of dietary iodide in the rat. Fundam. Appl. Toxicol. 1985, 5:672-678.
158. Harrington R.M., Shertzer H.G., Bercz J.P. Effects of chlorine dioxide on thyroid function in the African green monkey and the rat. J. Toxicol. Environ. Health 1986, 19:235-242.
159. Hart L., Fouts J. Further studies on the stimulation of hepatic microsomal drug metabolizing enzymes by DDT and its analogs. Arch. Exp. Pathol. Pharmacol. 1965, 249:486-500.
160. Hasegawa M., Kurabayashi Y., Ishii T., Yoshida K., Uebayashi N., Sato N., Kurosawa T. Intra-cage air change rate on forced-air-ventilated microisolation environment within cages: carbon dioxide and oxygen concentration. Exp. Anim. 1997, 46:251-257.
161. Hasenau J.J., Baggs R.B., Kraus A.L. Microenvironments in microisolation cages using BALB/c and CD-1 mice. Contemp. Top. Lab. Anim. Sci. 1993, 32:11-16.
162. Hastings J.S. Long term use of vermiculite. J. Inst. Anim. Tech. 1967, 18:184-190.
163. Hastings J.W., Menaker M. Physiological and biochemical aspects of circadian rhythms. Fed. Proc., Fed. Am. Soc., Exp. Biol. 1976, 35:2325-2357.
164. Hatch A.M., Wibert G.S., Zawidzka Z. Isolation syndrome in the rat. Toxicol. Appl. Pharmacol. 1965, 7:737-745.
165. Hayashi O., Kikuchi M. The effects of the light-dark cycle on humoral and cell-mediated immune response of mice. Chronobiologia 1982, 9:291-300.
166. Hayashi O., Kikuchi M. The influence of phase shift in the light-dark cycle on humoral immune responses of mice to sheep red blood cells and polyvinylpyrrolidone. J. Immunol. 1985, 134:1455-1461.
167. Hayes W.J. Toxicology of Pesticides 1975, Williams and Wilkins, Baltimore.
168. Heller R., Ballowitz L., Natszchka J. Wirkungen von blaulicht auf junge Gunn-ratten; bietrag zur frage der phototherapie bei hyperbilirubinamie. Monatsshrift fur Kinderheilkunde 1969, 117:437-440.
169. Hemminki A From molecular changes to customized therapy. Eur. J. Cancer 2002, 38:333-338.
170. Hessler J.R. Facilities to support research. Handbook of Facilities Planning: Vol. 2, Laboratory Animal Facilities 1991, 35-54. Van Nostrand Reinhold, New York. T. Ruys (Ed.).
171. Hessler J.R. Single versus dual-corridor systems: advantages, disadvantages, limitations and alternatives for effective contamination control. Handbook of Facilities Planning: Vol. 2, Laboratory Animal Facilities 1991, 59-67. Van Nostrand Reinhold, New York. T. Ruys (Ed.).
172. Hessler J.R. Methods of biocontainment. Current Issues and New Frontiers in Animal Research 1995, 61-68. Scientist Center for Animal Welfare, Greenbelt, MD. K.A. Bayne, L.M. Greene, E.D. Prentice (Eds.).
173. Hessler J.R., Broderson R., King C. Animal research facilities and equipment. Anthology of Biosafety 1. Perspectives on Laboratory Design 1999, 191-217. American Biological Safety Association, Mundelein, IL. J.Y. Richmond (Ed.).
174. Hessler J.R., Leary S.L. Design and management of animal facilities. Laboratory Animal Medicine 2002, 909-933. Academic Press, New York, NY. 2nd Ed. J. Fox, L.C. Anderson, F. Lowe, F.W. Quimby (Eds.).
175. Hisjarvi P., Junnila M. Happy rats: reliable results. Acta Physiol. Scand. 1986, 128(Suppl 554):32.
176. Hirsjarvi P.A., Valiaho T.V. Microclimate in two types of rat cages. Lab. Anim. 1987, 21:95-98.
177. Hoff J.C., Geldreich E.E. Comparison of the biocidal efficiency of alternative distinfectants. J. Amer. Water Works Assoc. 1981, 73:40-49.
178. Viruses of Laboratory Rodents. Monograph no. 20 1966, XIII-XIV. National Cancer Institute, Bethesda, MD. R. Holdenreid (Ed.).
179. Hoffman-Goetz L., MacNeil B., Arumugam Y. Effect of differential housing in mice on natural killer cell activity tumor growth, and plasma corticosterone. Proc. Soc. Exp. Biol. Med. 1992, 199:337-344.
180. Honma S., Suzuki A., Buchannan D.L., Katsu Y., Watanabe H., Iguchi T. Low dose effect of in utero exposure to bisphenol A and diethylstibestrol on female mouse reproduction. Reprod. Toxicol. 2002, 16:117-122.
181. Howdeshell K.L., Peterman P.H., Judy B.M., Taylor J.A., Orazio C.E., Ruhlen R.L., vom Saal F.S., Welshons W.V. Bisphenol A is released from used polycarbonate animal cages into water at room temperature. Environ. Health Perspect. 2003, 111:1180-1187.
182. Huerkamp M.J., Lehner N.D.M. Comparative effects of forced-air, individual cage ventilation or an absorbent bedding additive on mouse isolator cage microenvironment. Contemp. Top. Lab. Anim. Sci. 1994, 33:58-61.
183. Huerkamp M.J., Thompson W.D., Lehner N.D.M. Failed air supply to individually ventilated caging system causes acute hypoxia and mortality of rats. Contemp. Top. Lab. Anim. Sci. 2003, 42:454.
184. Hughes R.N., Syme L.A. The role of social isolation and sex in determining effects of chlordiazepoxide and methylphenidate on exploratory activity. Psychopharmacology 1972, 27:359-366.
185. Hunt P.A., Koehler K.E., Susiarjo M., Hodges C.A., Ilagan A., Voigt R.C., Thomas S., Thomas B.F., Hassold T.J. Bisphenol a exposure causes meiotic aneuploidy in the female mouse. Curr. Biol. 2003, 13:546-553.
186. Institute of Laboratory Animal Resources Laboratory Animal Housing 1978, Institute of Laboratory Animal Resources, National Academy of Science, Washington, DC.
187. Irving L. Terrestrial animals in cold: birds and mammals. Handbook of Physiology, Section 4 1964, 361-377. American Physiological Society, Washington, DC.
188. Ishikawa M., Ozaki M., Takayanagi Y., Sasaki K. Induction of hepatic cytochrome P-450 and drug metabolism by doxapram in the mouse. Res. Commun. Chem. Pathol. Pharmacol. 1991, 72:109-112.
189. Iwarsson K., Noren L. Comparison of microenvironmental conditions in standard versus forced-air ventilated rodent filter-top cages. Scand. J. Lab. Anim. Sci. 1992, 19:167-173.
190. Izaraeli S., Rechavi G. Molecular medicine: an overview. Isr. Med. Assoc. J. 2002, 4:638-640.
191. Jacob H.J. Functional genomics and rat models. Genome Res. 1999, 9:1013-1016.
192. Jacob H.J., Kwitek A.E. Rat genetics: attaching physiology and pharmacology to the genome. Nat. Rev. Genet. 2002, 3:33-42.
193. Jessop J.J., Bayer B.M. Time-dependent effects of isolation on lymphocyte and adrenal activity. J. Neuroimmunol. 1989, 23:143-147.
194. Jessop J.J., Gale K., Bayer B.M. Enhancement of rat lymphocyte proliferation after prolonged exposure to stress. J. Neuroimmunol. 1987, 16:261-271.
195. Jessop J.J., Gale K., Bayer B.M. Time-dependent enhancement of lymphocyte activation by mitogens after exposure to isolation or water scheduling. Life Sci. 1988, 43:1133-1140.
196. Joasoo A., McKenzie J.M. Stress and immune response in rats. Int. Arch. Allergy. Appl. Immunol. 1976, 50:659-663.
197. Johnson T., Lavender J.F., Hultin E., Rasmussen A.F. The influence of avoidance-learning stress on resistance to cocksackie B virus in mice. J. Immunol. 1963, 91:569-575.
198. Jonas A.M. Laboratory animal facilities. J. Am. Vet. Med. Assoc. 1965, 146:600-606.
199. Jonas A.M. Long-term holding of laboratory rodents. ILAR News 1976, 19:1-25.
200. Jori A., Bianchetti A., Prestini P.E. Effect of essential oils on drug metabolism. Biochem. Pharmacol. 1969, 18:2081-2085.
201. Jori A., DiSalle E., Santini V. Daily rhythmic variation and liver drug metabolism in rats. Biochem. Pharmacol. 1971, 29:2965-2969.
202. Joseph I.M., Suthanthirarajan N., Namasivayam A. Effect of heat stress on certain immunological parameters in albino rats. Indian J. Physiol. Pharmacol. 1991, 35:269-271.
203. Junli H., Li W., Nenqi R., Fang M., Li J. Disinfection effect of chlorine dioxide on bacteria in water. Water Res. 1997, 31:607-613.
204. Junli H., Li W., Nenqi R., Li L.X., Fun S.R., Guanle Y. Disinfection effect of chlorine dioxide on viruses, algae, and animal planktons in water. Water Res. 1997, 31:455-460.
205. Justice M.J. Capitalizing on large-scale mouse mutagenesis screens. Nat. Rev. Genet. 2000, 1:109-115.
206. Kanzaki M., Fujieda M., Furukawa T. Effects of suspension of air-conditioning on airtight-type racks. Exp. Anim. 2001, 50:379-385.
207. Karim A., Arslan M.I. Isolation modifies the behavioral response in rats. Bangladesh Med. Res. Counc. Bull. 2000, 26:27-32.
208. Karp J.D., Cohen N., Moynihan J.A. Quantitative differences in interleukin-2 and interleukin-4 production by antigen-stimulated splenocytes from individually- and group-housed mice. Life Sci. 1994, 55:789-795.
209. Karp J.D., Moynihan J.A., Ader R. Effects of differential housing on the primary and secondary antibody responses of male C57BL/6 and BALB/c mice. Brain Behav. Immun. 1993, 7:326-333.
210. Karp J.D., Moynihan J.A., Ader R. Psychosocial influences on immune responses to HSV-1 infection in BALBc mice. Brain Behav. Immun. 1997, 11:47-62.
211. Katz D.M., Steinberg H. Factors which might modify morphine dependence in rats. Biochemical and Pharmacological Aspects of Dependence and Reports on Marihuana Research 1972, 57-66. De Erven Bohn, Haarlem. H.M. Prang (Ed.).
212. Keller G.L., Mattingly S.F., Knapke F.B. A forced-air individually ventilated caging system for rodents. Lab. Anim. Sci. 1983, 33:580-582.
213. Keller L.S.F., White W.J., Snider M.T., Lang C.M. An evaluation of intra-cage ventilation in three animal caging systems. Lab. Anim. Sci. 1989, 39:237-242.
214. Kline L.B., Hull R.N. The virucidal properties of peracetic acid. Am. J. Clin. Pathol. 1960, 33:30-33.
215. Klir P., Bondy R., Lachout J., Hanis T. Physiological changes in laboratory rats caused by different housing. Physiol. Bohemoslov. 1984, 33:111-121.
216. Knapka J.J. Nutrition of rodents. Vet. Clin. N. Am. Exot. Anim. Pract. 1999, 2:153-167.
217. Knights K.M., Gourlay G.K., Cousins M.J. Changes in rat hepatic microsomal mixed function oxidase activity following exposure to halothane under various oxygen concentrations. Biochem. Pharmacol. 1987, 36:897-906.
218. Kodam K.M., Adav S.S., Govindwar S.P. Effect of sulfamethazine on phenobarbitol and benzo[a]pyrene induced hepatic microsomal mixed function oxidase system in rats. Toxicol. Lett. 1996, 87:25-30.
219. Kodam K.M., Govindwar S.P. In vivo and in vitro effect of sulfamathazine on hepatic mixed function oxidases in rats. Vet. Hum. Toxicol. 1997, 39:141-146.
220. Koehler K.E., Voigt R.C., Thomas S., Lamb B., Urban C., Hassold T., Hunt P.A. When disaster strikes: rethinking caging materials. Lab. Anim. 2003, 32:24-27.
221. Kolmodin B., Azarnoff D.L., Sjoqvist F. Effect of environmental factors in drug metabolism: decreased plasma half-life of antipyrine in workers exposed to chlorinated hydrocarbon insecticides. Clin. Pharmacol. Ther. 1969, 10:638-642.
222. Koner B.C., Banerjee B.D., Ray A. Organochlorine pesticide-induced oxidative stress and immune suppression in rats. Indian J. Exp. Biol. 1998, 36:395-398.
223. Kostowski W., Czlonkowski A., Rewerski W., Piechocki T. Morphine action in grouped and isolated rats and mice. Psychopharmacology 1977, 53:191-193.
224. Kraft L.M. The manufacturing, shipping and receiving and quality control of rodent bedding materials. Lab. Anim. Sci. 1980, 30:366-374.
225. Krebs H., Macht M., Weyers P., Weijers H.G., Janke W. Effects of stressful noise on eating and non-eating behavior in rats. Appetite 1996, 26:193-202.
226. Krechniak J., Wrzesniowska K. Effects of pyrethroid insecticides on hepatic microsomal enzymes in rats. Environ. Res. 1991, 55:129-134.
227. Krishnan A.V., Stathis P., Permuth S.F., Tokes L., Feldman D. Bisphenol-A: an estrogenic substance is released from polycarbonate flaks during autoclaving. Endocrinology 1993, 132:2279-2286.
228. Krynicki M., Olszewski W.L. Influence of thermal stress on lymphocyte migration pattern in rats. Arch. Immunol. Ther. Exp. (Warsz) 1989, 37:601-607.
229. Kwitek-Black A.E., Jacob H.J. The use of designer rats in the genetic dissection of hypertension. Curr. Hypertens. Rep. 2001, 3:12-18.
230. Lambert H.H. Continuous red light induces persistent estrus without retinal degeneration in the albino rat. Endocrinology 1975, 97:208-210.
231. Landi M.S., Kreider J.W., Lang C.M., Bullock L.P. Effects of shipping on the immune function in mice. Am. J. Vet. Res. 1982, 43:1654-1657.
232. Lang C., Harrell G.T. A Comprehensive Animal Facility for a College of Medicine 1971, USHEW, PHS, NIH, Bethesda, MD.
233. Lang C., Vesell E.S. Environmental and genetic factors affecting laboratory animals: impact on biomedical research. Fed. Proc. Fed. Am. Soc. Exp. Biol. 1976, 35:1123-1124.
234. LeBouton A.V., Handler S.D. Persistent circadian rhythmicity of protein synthesis in liver of starved rats. Experientia 1971, 27:1031-1032.
235. Ledermann B. Embryonic stem cells and gene targeting. Exp. Physiol. 2000, 85:603-613.
236. Les E.P. Cage population density and efficiency of feed utilization in inbred mice. Lab. Anim. Care 1968, 18:305-313.
237. Les E.P. Pressurized, individually ventilated (PIV) and individually exhausted caging for laboratory mice. Lab. Anim. Sci. 1983, 33:495.
238. Liimatainen A., Muller D., Vartiainen T., Jahn F., Kleeberg U., Klinger W., Hanninen O. Chlorinated drinking water is mutagenic and causes 3-methylcholanthrene type induction of hepatic monooxygenase. Toxicology 1988, 51:281-289.
239. Lindblom B., Motylewski K. "Disaster Planning for Cultural Institutions" technical leaflet 183 1993, American Association for State and Local History, Nashville, TN.
240. Lindsey J.R., Conner M.W., Baker H.J. Physical, chemical and microbial factors affecting biologic responses. Laboratory Animal Housing 1978, 37-43. Institute for Laboratory Animal Resources, National Academy of Science, Washington, DC.
241. Lindsey J.R., Davidson M.K., Schoeb T.R., Cassell G.H. Mycoplasma pulmonis-host relationships in a breeding colony of Sprague-Dawley rats with enzootic murine respiratory mycoplasmosis. Lab. Anim. Sci. 1985, 35:597-608.
242. Lipman N.S. Microenvironmental conditions in isolator cages: an important research variable. Lab. Anim. 1992, 21:23-26.
243. Lipman N.S. Strategies for architectural integration of ventilated caging systems. Contemp. Top. Lab. Anim. Sci. 1993, 32:7-12.
244. Lipman N.S. Isolator rodent caging systems (state of the art): a critical view. Contemp. Top. Lab. Anim. Sci. 1999, 38:9-17.
245. Lipman N.S., Corning B.F., Coiro M.A. The effects of intracage ventilation on microenvironmental conditions in filter-top cages. Lab. Anim. 1992, 26:206-210.
246. Lipman N.S., Corning B.F., Saifuddin M. Evaluation of isolator caging systems for protection of mice against challenge with mouse hepatitis virus. Lab. Anim. 1993, 27:134-140.
247. Lundberg V. Dominanzstrukturen mannlicher laborratten. Zeitschr. Versuchstierk 1986, 28:257-268.
248. Magee P.N. Tests for carcinogenic potential. Methods in Toxicology 1970, 158-196. Blackwells, Oxford. G.E. Paget (Ed.).
249. Manning P.J., Banks K.L. The effects of transportation on the aged rat. Publication 1591 1968, 98-103. National Academy of Sciences, Washington, DC.
250. Manser C.E., Morris T.H., Broom D.M. An investigation into the effects of solid or grid cage flooring on the welfare of laboratory rats. Lab. Anim. 1995, 2(9):353-363.
251. Manser C.E., Morris T.H., Broom D.M. The use of a novel operant test to determine the strength of preference for flooring in laboratory rats. Lab. Anim. 1996, 30:1-6.
252. Markaverich B., Mani S., Alejandro M.A., Mitchell A., Markaverich D., Brown T., Velez-Trippe C., Murchison C., O'Malley B., Faith R. A novel endocrine-disrupting agent in corn with mitogenic activity in human breast and prostatic cancer cells. Environ. Health Persp. 2002, 110:169-177.
253. Markaverich B.M., Alejandro M.A., Markaverich D., Zitzow L., Casajuna N., Camarao N., Hill J., Bhirdo K., Faith R., Turk J., Crowley J.R. Identification of an endocrine disrupting agent from corn with mitogenic activity. Biochem. Biophys. Res. Comm. 2002, 291:692-700.
254. Markey C.M., Coombs M.A., Sonnenschein C., Soto A.M. Mammalian development in a changing environment: exposure to endocrine disruptors reveals the developmental plasticity of steroid-hormone target organs. Evol. Dev. 2003, 5:67-75.
255. Markey C.M., Luque E.H., de Toro M.M., Sonnenschein C., Soto A.M. In utero exposure to bisphenol A alters the development and tissue organization of the mouse mammary gland. Biol. Reprod. 2001, 65:1215-1223.
256. Markey C.M., Rubin B.S., Soto A.M., Sonnenschein C. Endocrine disruptors: from Wingspread to environmental developmental biology. J. Steriod Biochem. Mol. Biol. 2002, 83:235-244.
257. Maslova L.N., Bulygina V.V., Markel A.L. Chronic stress during prepubertal development: immediate and long lasting effects on arterial blood pressure and anxiety-related behavior. Psychoneuroendocrinology 2002, 27:549-561.
258. Matsumura F. Toxicology of Insecticides 1975, Plenum Press, New York.
259. Mayeux P., Dupepe L., Dunn K., Balsmo J., Domer J. Massive fungal contamination in animal care facilities traced to bedding supply. Appl. Environ. Microbiol. 1995, 61:2297-2301.
260. McCarthy D.O., Ouimet M.E., Daun J.M. The effects of noise stress on leukocyte function in rats. Res. Nurs. Health 1992, 15:131-137.
261. Control of the Animal House Environment 1976, Laboratory animals Ltd., London. T. McSheehy (Ed.).
262. Meier J.R., Bull R.J., Stober J.A., Cimino M.C. Evaluation of chemicals used for drinking water disinfection for production of chromosomal damage and sperm-head abnormalities in mice. Environ. Mutagen. 1985, 7:201-211.
263. Melnick R., Lucier G., Wolfe M., Hall R., Stancel G., Prins G., Gallo M., Reuhl K., Ho S.M., Brown T., Moore J., Leakey J., Haseman J., Kohn M. Summary of the National Toxicology Program's report of the endocrine disruptors low-dose peer review. Environ. Health Perspect. 2002, 110:427-431.
264. Militzer K., Reinhard H.J. Rank position in rats and their relations to tissue parameters. Physiol. Psychol. 1982, 10:251-260.
265. Milligan S.R., Sales G.D., Khirnykh K. Sound levels in rooms housing laboratory animals: an uncontrolled daily variable. Physiol. Behav. 1993, 53:1067-1076.
266. Mills D.E., Ward R. Attenuation of psychosocial stress-induced hypertension by gamma-linolenic acid (GLA) administration in rats. Proc. Soc. Exp. Biol. 1984, 176:32-37.
267. Moore G.S., Calabrese E.J. The effects of chlorine dioxide and sodium chlorite on erythrocytes of A/J and C57L J mice. J. Environ. Pathol. Toxicol. 1980, 4:513-524.
268. Moreadith R.W., Radford N.B. Gene targeting in embryonic stem cells: the new physiology and metabolism. J. Mol. Med. 1997, 75:208-216.
269. Morinan S., Leonard B.E. Some anatomical and physiological correlates of social isolation in the young rat. Physiol. Behav. 1980, 24:637-640.
270. Morita T., Tokura H. The influence of different wavelengths of light on human biological rhythms. Appl. Human Sci. 1998, 17:91-96.
271. Murakami H. Difference between internal and external environment of the mouse cage. Lab. Anim. Sci. 1971, 21:680-684.
272. Nair V., Casper R. The influence of light on daily rhythm in hepatic drug metabolizing enzymes in rat. Life Sci. 1969, 21:680-684.
273. Naranjo J.R., Fuentes J.A. Association between hypoalgesia and hypertension in rat after short-term isolation. Neuropharmacology 1985, 24:167-171.
274. Nayfield K.C., Besch E.L. Comparative responses of rabbits and rats to elevated noise. Lab. Anim. Sci. 1981, 31:386-390.
275. Newberne P.M. Influence on pharmacological experiments of chemicals and other factors in diets of laboratory animals. Fed. Proc., Fed. Am. Soc. Exp. Biol. 1975, 34:209-218.
276. Newberne P.M., Fox J.G. Chemicals and toxins in the animal facility. Laboratory Animal Housing 1978, 118-138. Institute of Laboratory Animal Resources, National Academy of Sciences, Washington, DC.
277. Newberne P.M., McConnell R.G. Dietary nutrients and contaminants in laboratory animal experimentation. J. Environ. Pathol. Toxicol. 1980, 4:105-122.
278. Nielsen F.H., Bailey B. The fabrication of plastic cages for suspension in mass air flow racks. Lab. Anim. Sci. 1979, 29:502-506.
279. Nielsen J.B., Andersen O., Svendsen P. Hepatic O-demethylase activity in mice on different types of bedding. Zeitschr. Versuchstierk. 1986, 28:69-75.
280. Niesink R.J.M., van Ree J.M. Short-term isolation increases social interactions of male rats: A parametric analysis. Physiol. Behav. 1982, 29:819-825.
281. Nunez M.J., Mana P., Linares D., Riveiro M.P., Balboa J., Suarez-Quintanilla J., Maracchi M., Mendez M.R., Lopez J.M., Freire-Garabal M. Music, immunity and cancer. Life Sci. 2002, 71:1047-1057.
282. Ohishi N., Imaoka S., Funae Y. Changes in content of P-450 isozymes in hepatic and renal microsomes of the male rat treated with cis-diamminedichloroplatinum. Xenobiotica 1994, 24:873-880.
283. Orme J., Taylor D.H., Laurie R.D., Bull R.J. Effects of chlorine dioxide on thyroid function in neonatal rats. J. Toxicol. Envoiron. Health 1985, 15:315-322.
284. Ortman J.A., Sahenk Z., Mendell J.R. The experimental production of Renaut bodies. J. Neurol. Sci. 1983, 62:233-241.
285. Ostby J., Kelce W.R., Lambright C., Wolf C.J., Mann P., Gray L.E. The fungicide procymidone alters sexual differentiation in the male rat by acting as an androgen-receptor antagonist in vivo and in vitro. Toxicol. Ind. Health 1999, 15:80-93.
286. O'Steen W.K., Anderson K.V. Photoreceptor degeneration after exposure of rats to incandescent illumination. Z. Zellforsch. Mikrosk. Anat. 1972, 127:306-313.
287. O'Steen W.K., Brodish A. Neuronal damage in the rat retina after chronic stress. Brain. Res. 1985, 344:231-239.
288. Ozaki M., Ishikawa M., Takayanagi Y., Sasaki K. Sex-related differences in rat liver microsomal enzymes and their induction by doxapram. J. Pharm. Pharmacol. 1993, 45:975-978.
289. Palanza P., Howdeshell K.L., Parmigiani S., vom Saal F.S. Exposure to a low dose of bisphenol A during fetal life or in adulthood alters maternal behavior in mice. Environ. Health Perspect. 2002, 110(Suppl 3):415-422.
290. Panksepp J. Brief social isolation, pain responsivity, and morphine analgesia in young rats. Psychopharmacol. 1980, 72:111-112.
291. Peace T.A., Singer A.W., Niemuth N.A., Shaw M.E. Effects of caging type and animal source on the development of foot lesions in Sprague Dawley rats (Rattus norvegicus). Contemp. Top. Lab. Anim. Sci. 2001, 40:17-21.
292. Peeters J.E., Mazas E.A., Masschelein W.J., Martinez de Maturana I.v., Debacker E. Effect of disinfection of drinking water with ozone or chlorine dioxide on survival of cryptosporidium parvum oocysts. Appl. Environ. Microbiol. 1989, 55:1519-1522.
293. Pelkonen K.H., Hanninen O.O. Cytotoxicity and biotrans-formation inducing activity of rodent bedding: a global survey using the Hepa-1 assay. Toxicol. 1997, 122:73-80.
294. Periquet A., Derache R. Hepatic microsomal monoxygenase inhibition by nabam in the rat. Toxicol. Eur. Res. 1981, 3:285-291.
295. Perkins S.E., Lipman N.S. Characterization and quantification of microenvironmental contaminants in isolator cages with a variety of contact beddings. Contemp. Top. Lab. Anim. Sci. 1995, 34:93-97.
296. Perkins S.E., Lipman N.S. Evaluation of microenvironmental conditions and noise generation in three individually ventilated rodent caging systems and static isolator cages. Contemp. Top. Lab. Anim. Sci. 1996, 35:61-65.
297. Peterson E.A. Noise and laboratory animals. Lab. Anim. Sci. 1980, 30:422-439.
298. Pfaff J. Noise as an environmental problem in the animal house. Lab Anim. 1974, 8:347-354.
299. Pick J.R., Little J.M. Effect of type of bedding material on thresholds of penthylenetetrazole convulsions in mice. Lab. Anim. Care 1965, 15:28-33.
300. Plant S.M., Alder R., Friedman S.B., Ritterson A.L. Social factors and resistance to malaria in the mouse: effects of group vs. individual housing on resistance to Plasmodium berghei infection. Psychosom. Med. 1969, 31:536-540.
301. Pleasants J.R. Gnotobiotics. Handbook of Laboratory Animal Science 1974, Vol. 1:119-174. CRC Press, Cleveland, OH. E.C. Melby, N.H. Altman (Eds.).
302. Port C.D., Kaltenbach J.P. The effect of corncob bedding on reproductivity and leucine incorporation in mice. Lab. Anim. Care 1969, 10:46-49.
303. Potgieter F.J., Wilke P.J. Laboratory animal bedding: a review of wood and wood constituents as a possible source of external variables that could influence experimental results. Anim. Technol. 1992, 43:65-88.
304. Pozdeyev N.V., Lavrikova E.V. Diurnal changes of tyrosine, dopamine, and dopamine metabolites content in the retina of rats maintained at different lighting conditions. J. Mol. Neurosci. 2000, 15:1-9.
305. Prabhakaran K., Suthanthirarajan N., Namasivayam A. Biochemical changes in acute noise stress in rats. Indian J. Physiol. Pharmacol. 1988, 32:100-104.
306. Prater M.R., Gogal R.M., Blaylock B.L., Longstreth J., Holladay S.D. Single-dose topical exposure to the pyrethroid insecticide, permethrin in C57BL/6N mice: effects on thymus and spleen. Food Chem. Toxicol. 2002, 40:1863-1873.
307. Pryce C.R., Bettschen D., Bahr N.I., Feldon J. Comparison of the effects of infant handling, isolation, and nonhandling on acoustic startle, prepulse inhibition, locomotion, and HPA activity in the adult rat. Behav. Neurosci. 2001, 115:71-83.
308. Pucak G.J., Lee C.S., Zaino A.S. Effects of prolonged high temperature on testicular development and fertility in the male rat. Lab. Anim. Sci. 1977, 27:76-77.
309. Punareewattana K., Smith B.J., Blaylock B.L., Longstreth J., Snodgrass H.L., Gogal R.M., Prater R.M., Holladay S.D. Topical permethrin exposure inhibits antibody production and macrophage function in C57BL/6N mice. Food Chem. Toxicol. 2001, 39:133-139.
310. Quraishi M.S. Biochemical Insect Control: Its Impact on Economy, Environment and Natural Selection 1977, John Wiley and Sons, New York.
311. Rabin B.S., Lyte M., Hamill E. The influence of mouse strain and housing on the immune response. J. Neuroimmunol. 1987, 17:11-16.
312. Rabin B.S., Salvin S.B. Effect of differential housing and time on immune reactivity to sheep erythrocytes and Candida. Brain Behav. Immun. 1987, 1:267-275.
313. Radzialowski F.M., Bousquet W.F. Daily rhythmic variation in hepatic drug metabolism in the rat and mouse. J. Pharmacol. Exp. Ther. 1968, 163:229-238.
314. Ramos J.G., Varayoud J., Sonnenschein C., Soto A.M., de Toro M.M., Luque E.H. Prenatal exposure to low doses of bisphenol A alters the periductal stroma and glandular cell function in the rat ventral prostate. Biol. Reprod. 2001, 65:1271-1277.
315. Ras T., Van De Ven M., Patterson-Kane E.G., Nelson K. Rats' preferences for corn versus wood-based bedding and nesting materials. Lab. Anim. 2002, 36:420-425.
316. Rasmussen A.F. Emotions and immunity. Ann. NY Acad. Sci. 1969, 164:458-461.
317. Reeb C.K., Jones R.B., Bearg D.W., Cih P.E., Bedigian H., Myers D.D., Paigen B. Microenvironment in ventilated animal cages with differing ventilation rates, mice populations, and frequency of bedding changes. Contemp. Top. Lab. Anim. Sci. 1998, 37:43-49.
318. Reeb-Whitaker C.K., Harrison D.J., Jopnes R.B., Kacergia J.B., Myers D.D., Paigen B. Control strategies for aeroallergens in an animal facility. J. Allergy Clin. Immunol. 1999, 103:139-146.
319. Reeb-Whitaker C.K., Paigen B., Beamer W.G., Bronson R.T., Churchill G.A., Schweitzer I.B., Myers D.D. The impact of reduced frequency of cage changes on the health of mice housed in ventilated cages. Lab. Anim. 2001, 35:58-73.
320. Reiter R.J. Comparative effects of continual lighting and pinealectomy on the eyes, the Harderian glands and reproduction in pigmented and albino rats. Comp. Biochem. Physiol. 1973, 44:503-509.
321. Renstrom A., Bjoring G., Hoglund A.U. Evaluation of individually ventilate cage systems for laboratory rodents: occupational health aspects. Lab. Anim. 2001, 35:42-50.
322. Richa J. Production of transgenic mice. Mol. Biotechnol. 2001, 17:261-268.
323. Rikans L.E., Moore D.R. Acetaminophen hepatotoxicity in aging rats. Drug Chem. Toxicol. 1988, 11:237-247.
324. Riley V. Psychoneuroendocrine influence on immunocompetence and neoplasia. Science 1981, 212:1100-1109.
325. Rivard G.F., Neff D.E., Cullen J.F., Welch S.W. A novel vented microisolation container for caging animals: microenvironmental comfort in a closed-system filter cage. Contemp. Top. Lab. Anim. Sci. 2000, 39:22-27.
326. Robertson E.J. Using stem cells to introduce mutations into the mouse germ line. Biol. Reprod. 1991, 44:238-245.
327. Robinson E.C., Nair R.S. The genotoxic poteintial of linear alkylbenzene mixtures in a short-term test battery. Fundam. Appl. Toxicol. 1992, 18:540-548.
328. Robinson E.C., Schroeder R.E. Reproductive and developmental toxicity studies of a linear alkylbenzene mixture in rats. Fundam. Appl. Toxicol. 1992, 18:549-556.
329. Rock F.M., Landi M.S., Hughes H.C., Gagnon R.C. Effects of caging type and group size on selected physiologic variables in rats. Contemp. Top. Lab. Anim. Sci. 1997, 36:69-72.
330. Roe F.J.C. Spontaneous tumors in rats and mice. Food Cosmet. Toxicol. 1965, 3:707-720.
331. Romanovsky A.A., Ivanov A.I., Shimansky Y.P. Selected contribution: ambient temperature for experiments in rats: a new method for determining the zone of thermal neutrality. J. Appl. Physiol. 2002, 92:2667-2679.
332. Thermobiology 1967, Academic Press, New York. A.H. Rose (Ed.).
333. Rowe W.P., Hartley J.W., Huebner R.J. Polyoma and other indigenous mouse viruses. The Problems of Laboratory Animal Diseases 1962, 131. Academic Press, New York. R.J.C. Harris (Ed.).
334. Roy D., Colerangle J.B., Singh K.P. Is exposure to environmental or industrial endocrine disrupting estrogen-like chemicals able to cause genomic instability?. Front. Biosci. 1998, 3:913-921.
335. Royals M., Getzy D.M., Vandewoude S. High fungal spore load in corncob bedding associated with fungal-induced rhinitis in two rats. Contemp. Top. Lab. Anim. Sci. 1999, 38:64-66.
336. Rubin B.S., Murray M.K., Damassa D.A., King J.C., Soto A.M. Pernatal exposure to low doses of bisphenol A affects body weight, patterns of estrous cyclicity, and plasma LH levels. Environ. Health Perspect. 2001, 109:675-680.
337. Handbook of Facilities Planning, Volume 2: Laboratory Animal Facilities 1991, Van Nostrand Reinhold, New York. T. Ruys (Ed.).
338. Sabiston B.H., Rose J.E., Cinader B. Temperature stress and immunity in mice: effects of environmental temperature on the antibody response to human immunoglobulin of mice, differing in age and strain. J. Immunogenet. 1978, 5:197-212.
339. Saito T.R., Motomura N., Taniguchi K., Hokao R., Arkin A., Takahashi K.W., Sato N.L. Effect of cage size on sexual behavior pattern in male rats. Contemp. Top. Lab. Anim. Sci. 1996, 35:80-82.
340. Sales G.D., Wilson K.J., Spencer K.E., Milligan S.R. Environmental ultrasound in laboratories and animal houses: a possible cause for concern in the welfare and use of laboratory animals. Lab. Anim. 1988, 22:369-375.
341. Saltarelli C.G., Coppola C.P. Influence of visible light on organ weights of mice. Lab. Anim. Sci. 1979, 29:319-322.
342. Salvia M., Weisbroth S.H., Paganelli R.G. Lab animals show less "shipment stress" given drinking water. Lab. Anim. 1979, 8:38-42.
343. Salvin S.B., Rabin B.S., Neta R. Evaluation of immunologic assays to determine the effects of differential housing on immune reactivity. Brain Behav. Immun. 1990, 4:180-188.
344. Sanvordecker D.R., Lambert H.J. Environmental modification of mammalian drug metabolism and biological response. Drug Metab. Rev. 1974, 3:201-229.
345. Schoeb T.R., Davidson M.K., Lindsey J.R. Intracaga ammonia promotes growth of Mycoplasma pulmonis in the respiratory tract of rats. Infect. Immun. 1982, 38:212-217.
346. Schoket B., Vincze I. Induction of rat hepatic drug metabolizing enzymes by substituted urea herbicides. Acta Pharmacol. Toxicol. 1985, 56:283-288.
347. Schonfelder G., Flick B., Mayr E., Talsness C., Paul M., Chahoud I. In utero exposure to low doses of bisphenol A lead to long-term deleterious effects in the vagina. Neoplasia 2002, 4:98-102.
348. Schuhr B. Social structure and plasma corticosterone level in female albino mice. Physiol. Behav. 1987, 40:689-693.
349. Sedlacek R.S., Orcutt R.P., Suit H.D., Rose E.F. A flexible barrier at cage level for existing colonies: Production and maintenance of a limited stable anaerobic flora in a closed inbred mouse colony. Recent Advances in Germfree Research: Proceedings of the VIIth International Symposium on Gnotobiology 1981, 65-69. Tokai University Press, Tokyo. S. Sasaki, A. Ozawa, K. Hashimoto (Eds.).
350. Sellers E.A. Adaptive and related phenomena in rats exposed to cold: a review. Revue Canadienne de Biologie 1957, 16:175-188.
351. Semple-Rowland S.L., Dawson W.W. Cyclic light intensity threshold for retinal damage in albino rats raised under 6 1x. Exp. Eye Res. 1987, 44:643-661.
352. Semple-Rowland S.L., Dawson W.W. Retinal cyclic light damage threshold for albino rats. Lab. Anim. Sci. 1978, 37:289-298.
353. Serrano L.J. Carbon dioxide and ammonia in mouse cages: effect of cage covers, population, and activity. Lab. Anim. Sci. 1971, 21:75-85.
354. Serrano L.J. Defined mice in a radiobiological experiment. Defining the Laboratory Animal 1971, 13-41. Institutes of Laboratory Animal Resources, National Academy of Science, Washington, DC.
355. Sharp P.E., LaRegina M.C. The Laboratory Rat 1998, 30. CRC Press, Boca Raton.
356. Shaw D.C., Gallagghe R.H. Group or singly housed rats?. Standards in Laboratory Animal Management, Part 1 1984, 65-70. Universities Federation for Animal Welfare, Herferdshire, United Kingdom.
357. Shapiro R. Chemical contamination of drinking water: what it is and where it comes from. Lab Anim. 1980, 9:45-51.
358. Shysh A., Noujaim A.A. Alterations in hepatic microsomal drug metabolizing systems in cold stressed mice. Can. J. Pharm. Sci. 1972, 7:23.
359. Sigmund C.D. Major approaches for generating and analyzing transgenic mice. An overiew. Hypertension 1993, 22:599-607.
360. Simmons M.L., Brick J.O. The Laboratory Mouse Selection and Management 1970, 153-156. Prentice-Hall, Englewood Cliffs, NJ.
361. Simmons M.L., Robie D.M., Jones J.B., Serrano L.J. Effect of a filter cover on temperature and humidity in a mouse cage. Lab. Anim. 1968, 2:113-120.
362. Skowronski G.A., Abdel-Rahman M.S., Gerges S.E., Klein K.M. Teratologic evaluation of Alcide liquid in rats and mice, I. J. Appl. Toxicol. 1985, 5:97-103.
363. Slanetz C.A., Fratta I., Crouse C.W., Jones S.C. Stress and transportation of animals. Proc. Anim. Care Panel 1956, 7:278-289.
364. Smith M.M., Hargaden M. Developing a rodent enrichment program. Lab Anim. 2001, 30:36-41.
365. Solomon G.F. Stress and antibody response in rats. Int. Arch. Allergy Appl. Immunol. 1969, 35:97-104.
366. Sobrian S.K., Vaughn V.T., Ashe W.K., Markovic B., Djuric V., Jankovic B.D. Gestational exposure to loud noise alters the developmental and postnatal responsiveness of humoral and cellular componentsof the immune system in offspring. Environ. Res. 1997, 73:227-241.
367. Sokel E.H., Zuppinger K.A., Joss E.E. Effects of isolation, handling and restraint on growth of rats. Growth 1979, 43:1-6.
368. Solvay Advanced Polymers Questions and answers about bisphenol A in lab animal caging materials. Information Sheet Provided by Solvay Advanced Polymers to Interested Individuals 2003, 1-9.
369. Sorensen D.R. Laboratory animal facilities. Handbook of Laboratory Animal Science, Vol. I. Selection and Handling of Animals in Biomedical Research 1994, 79-87. CRC Press, Boca Raton, FL. P. Svendssen, J. Hau (Eds.).
370. Spalding J.F., Archuleta R.F., Holland L.M. Influence of visible color spectrum on activity in mice. Lab. Anim. Care 1969, 19:50-54.
371. Spalding J.F., Holland L.M., Tietjen G.L. Influence of the visible color spectrum on activity in mice, II: influence of sex, color and age on activity. Lab. Anim. Care 1969, 19:209-213.
372. Stauffacher M. Comparative studies on housing conditions. Harmonization of Laboratory Animal Husbandry 1966, 5-9. Royal Society of Medicine Press, London. P.N. O'Donoghue (Ed.).
373. Stefanski V. Social rearing conditions before weaning influence numbers and proportions of blood immune cells in laboratory rats. Dev. Psychobiol. 2001, 39:46-52.
374. Svendsen P. Environmental impact on animal experiments. Handbook of Laboratory Animal Science 1994, Vol. 1:191-202. CRC Press, Boca Raton, FL.
375. Takai Y., Tsutsumi O., Ikezuki Y., Kamei Y., Osuga Y., Yano T., Taketan Y. Preimplantation exposure to bisphenol A advances postnatal development. Reprod. Toxicol. 2001, 15:71-74.
376. Takeo Y. Influence of continuous illumination on estrus cycle of rats: time course of changes in levels of gonadotropins and ovarian steroids until occurrence of persistent estrus. Neuroendocrinology 1984, 39:97-104.
377. Tanner R.S. Comparative testing and evaluation of hard-surface biocides. J. Ind. Microbiol. 1989, 4:145.
378. Targowski S.P., Klucinski W., Babiker S., Nonnecke B.J. Effect of ammonia on in vivo and in vitro immune responses. Infect Immun. 1984, 43:289-293.
379. Terleckyj B., Axler D.A. Quantitative neutralization assay of fungicidal activity of disinfectants. Antimicrob. Agents Chemother. 1987, 31:794-798.
380. Thompson J.S., Brown S.A., Khurdayan V., Zeynalzadedan A., Sullivan P.G., Scheff S.W. Early effects of tribromoethanol, ketamine/xylazine, pentobarbital, and isolflurance anesthesia on hepatic and lymphoid tissue in ICR mice. Comp. Med. 2002, 52:63-67.
381. Tohei A., Suda S., Taya K., Hashimoto T., Kogo H. Bisphenol A inhibits testicular functions and increases luteinizing hormone secretion in adult male rats. Exp. Biol. Med. 2001, 226:216-221.
382. Torronen R., Pelkonen K., Karenlampi S. Enzyme-inducing and cytotoxic effects of wood-based materials used as bedding for laboratory animals: comparison by a cell culture study. Life Sci. 1989, 45:559-565.
383. Toth G.P., Long R.E., Mills T.S., Smith M.K. Effects of chlorine dioxide on the developing rat brain. J. Toxicol. Environ. Health 1990, 31:29-44.
384. Tu H., Diberadinis J., Lipman N.S. Determination of air distribution, exchange, velocity, and leakage in three individually ventilated rodent caging systems. Contemp. Top. Lab. Anim. Sci. 1997, 36:69-73.
385. Tuli J.S., Smith J.A., Morton D.B. Stress measurements in mice after transportation. Lab. Anim. 1994, 29:132-138.
386. Turner K., Sharpe R.M. Environmental oestrogens-present understanding. Rev. Repord. 1997, 2:69-73.
387. Twigger S., Lu J., Shimoyama M., Chen D., Pasko D., Long H., Ginster J., Chen C.F., Nigam R., Kwitek A., Eppig J., Maltais L., Maglott D., Schuler G., Jacob H., Tonellato P.J. Rat genome database (RGD): mapping disease onto the genome. Nucleic Acids Res. 2002, 30:125-128.
388. Tyl R.W., Myers C.B., Marr M.C., Thomas B.F., Keimowitz A.R., Brine D.R., Veselica M.M., Fail P.A., Chang T.Y., Seely J.C., Joiner R.L., Butala J.H., Dimond S.S., Cagen S.Z., Shiotsuka R.N., Stropp G.D., Waechter J.M. Three-generation reproductive toxicity study of dietary bisphenol A in CD Sprague-Dawley rats. Toxicol. Sci. 2002, 68:121-146.
389. Vadiei K., Berend K.L., Luke D.R. Isolation-induced renal functional changes in rats from four breeders. Lab. Anim. Sci. 1969, 40:56-59.
390. Van Damme A., Vanden Driessche T., Collen D., Chush M.K. Bone marrow stromal cells as targets for gene therapy. Curr. Gene Ther. 2002, 2:195-209.
391. Van der Touw J., Thrower S.J., Olley J. Non-specific neural stimuli and metabolic rhythms in rats. Physiol. Bohemos. 1978, 27:501-504.
392. Van de Weerd H.A., Baumans V., Koolhaas J.M., Van Zutphen L.F.M. Strain specific behavioural response to environmental enrichment in the mouse. J. Exp. Anim. Sci. 1994, 36:117-127.
393. Van Raajj M.T., Oortgiesen M., Timmerman H.H., Dobbe C.J., Van Loveren H. Time-dependent differential changes of immune function in rats exposed to chronic intermittent noise. Physiol. Behav. 1996, 60:1527-1533.
394. Verbiest H. Temperature and heat regulation. Folia Psychiatrica. Neurologica et Neurochirurgica Neerl 1956, 59:363-407.
395. Vesell E.S. Induction of drug-metabolizing enzymes in liver microsomes of mice and rats by soft wood bedding. Science 1967, 157:1057-1058.
396. Vesell E.S. Genetic and environmental factors affecting hexobarbital metabolism in mice. Ann. N. Y. Acad. Sci. 1968, 151:900-912.
397. Vessell E.S., Lang C.M. Environmental and genetic factors affecting laboratory animals: impact on biomedical research. Fed. Proc. 1976, 35:1123-1165.
398. Vessel E.S., Lang C.M., White W.J., Passananti G.T., Hill R.N., Clemens T.L., Liu D.K., Johnson W.D. Environmental and genetic factors affecting the response of laboratory animals to drugs. Fed. Proc. Fed. Am. Soc. Exp. Biol. 1976, 35:1125-1132.
399. Vesell E.S., Lang C.M., White W.J., Passananti G.T., Tripp S.L. Hepatic drug metabolism in rats: impairment in a dirty environment. Science 1973, 179:896-897.
400. Vessey S.H. Effects of grouping on levels of circulating antibodies in mice. Proc. Soc. Exp. Biol. Med. 1964, 115:225-255.
401. Vivitskaya L.V., Bikbulatova I.S., Vivitsky V. Changes in the content of nucleic acids and proteins in different brain parts of rats raised in enriched and impoverished media. Zhurnal Vysshei Deyatel Nosti 1982, 32:455-462.
402. Wade A.E., Holl J.E., Hilliard C.C., Molton E., Greene F.E. Alterations of drug metabolism in rats and mice by environment of cedar wood. Pharmacol 1968, 1:317-328.
403. Wagner S.L. Clinicla Toxicology of Agricultural Chemicals 1983, Noyes Data Corporation, Park Ridge.
404. Wahlstein D. Deficiency of corpus callosum varies with strain and supplier of the mice. Brain Res. 1982, 239:329-347.
405. Wallace M.E. Effects of stress due to deprivation and transport in different genotypes of house mouse. Lab. Anim. 1976, 10:335-347.
406. Weichbrod R.H., Cisar C.F., Miller J.G., Simmonds R.C., Alvares A.P.,
407. Weihe W.H. Temperature and humidity climatographs for rats and mice. Lab. Anim. Care 1965, 15:18-28.
408. Weihe W.H. The significance of the physical environment for the health and state of adaptation of laboratory animals. Defining the Laboratory Animal. IVth Symposium of the International Committee on Laboratory Animals 1971.
409. Weihe W.H. The effect of temperature on the action of drugs. Annu. Rev. Pharmacol. 1973, 13:409-425.
410. Weihe W.H. Influence of light on animals. Control of the Animal House Environment 1976, 63-76. Laboratory Animal, Ltd., London. T. McSheely (Ed.).
411. Weihe W.H., Schidlow J., Strittmatter J. The effect of light intensity on the breeding and development of rats and golden hamsters. Int. J. Biometeorol. 1969, 13:69-79.
412. Weisbroth S.H. Chemical contamination of lab animal beddings: problems and recommendations. Lab. Anim. 1979, 8:24-34.
413. Weisbroth S.H., Paganelli R.G., Salvia M. Evaluation of a disposable water system during shipment of laboratory rats and mice. Lab. Anim. Sci. 1977, 27:186-194.
414. Wiberg G.S., Airth J.M., Grive H.C. Methodology in long-term toxicity tests: A comparison of individual versus community housing. Fd. Cosmet. Toxicol. 1966, 4:47-55.
415. Wight D.C., Wagner T.E. Transgenic mice: a decade of progress in technology and research. Mutat. Res. 1994, 307:429-440.
416. Wilder P.J., Rizzino A. Mouse genetics in the 21st century: using gene targeting to create a cornucopia of mouse mutants possessing precise genetic modifications. Cytotechnology 1993, 11:79-99.
417. Williams D.I., Wells P.A. Differences in home-cage emergence in the rat in relation to infantile handling. Psychonom. Sci. 1970, 18:168-169.
418. Williams R.A., Howard A.G., Williams T.P. Retinal damage in pigmented and albino rats exposed to low levels of cyclic light following a single mydriatic treatment. Curr. Eye Res. 1985, 4:97-102.
419. Woods J.E. Interactions between primary (cage) and secondary (room) enclosures. Laboratory Animal Housing 1978, 65-83. National Academy of Science, Washington D.C.
420. Woods J.E. The animal enclosure: a microenvironment. Lab. Anim. Sci. 1980, 30:407-413.
421. Woods J.E., Besch E.L., Nevins R.G. Heat and moisture transfer in filter-top rodent cages. AALAS Publ. 1974, 74-3. Abstr. 77.
422. Wu D., Joiner G.N., McFarland A.R. A forced-air ventilation system for rodent cages. Lab. Anim. Sci. 1985, 35:499-504.
423. Wurbel H. Ideal homes? Housing effects on rodent brain and behavior. Trends Neurosci 2001, 24:207-211.
424. Wysocki A.B. The effect of intermittent noise exposure on wound healing. Adv. Wound Care 1996, 9:35-39.
425. Yagil R., Etzion Z., Berlyne G.M. Changes in rat milk quantity and quality due to variations in litter size and high ambient temperature. Lab. Anim. Sci. 1976, 26:33-37.
426. Yamamoto S., Ando M., Suzuki E. High-temperature effects on antibody response to viral antigen in mice. Exp. Anim. 1999, 48:9-14.
427. Yamauchi C., Fujita S., Obara T., Ueda T. Effects of room temperature on reproduction, body and organ weights, food and water intake, and hematology in rats. Lab. Anim. Sci. 1981, 31:251-258.
428. Yamauchi C., Takahashi H., Ando A. Effect of environmental temperature on physiological events in mice. 1: relationship between environmental temperature and number of caged mice. Jap. J. Vet. Sci. 1965, 27:471-478.
429. Yoshida K., Okamoto M., Tajima M., Kurosawa T. Invention of a forced-air-ventilated micro-isolation cage and rack system: environment, within cages: temperature and ammonia concentration. Exp. Anim. 1995, 43:703-710.
430. Zakem H.B., Alliston C.W. The effects of noise level and elevated ambient temperatures upon selected reproductive traits in female Swiss-Webster mice. Lab. Anim. Sci. 1974, 24:469-475.