Failed air supply to individually ventilated caging system causes acute hypoxia and mortality of rats

Contemporary Topics in Laboratory Animal Science

Volumn 42, Issue 3, 2003, Pages 44-45

  Huerkamp, Michael J ^a   Thompson, Wesley D ^a   Lehner, Noel D M ^a  

^a EMORY UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON DIOXIDE;

AIR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CAGE; CONTROLLED STUDY; ELECTRIC POWER PLANT; FEMALE; HYPOXIA; MORTALITY; NONHUMAN; OXYGEN CONCENTRATION; OXYGEN SUPPLY; POWER SUPPLY; RAT; ROOM VENTILATION; WEANING;

ANIMALS; ANIMALS, LABORATORY; ANIMALS, SUCKLING; ANOXIA; ENVIRONMENT, CONTROLLED; FEMALE; HOUSING, ANIMAL; RATS; RATS, LONG-EVANS; VENTILATION;

ANIMALIA;

EID: 0042320384     PISSN: 10600558     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Lipman, N. S. 1999. Isolator rodent caging systems (state of the art): a critical review. Contemp. Top. Lab. Anim. Sci. 38(5):9-17.
2. Renstrom, A., G. Bjoring, and A. U. Hoglund. 2001. Evaluation of individually ventilated cage systems for laboratory rodents: occupational health aspects. Lab. Anim. 35(1):42-50.
3. Huerkamp, M. J., D. L. Dillehay, and N. D. M. L. Lehner. 1994. Effect of intracage ventilation and automatic watering on outbred mouse reproductive performance and weanling growth. Contemp. Top. Lab. Anim. Sci. 33(5):58-62.
4. Serrano, L. J. 1971. Carbon dioxide and ammonia in mouse cages: effect of cage covers, population, and activity. Lab. Anim. Sci. 21(1):75-85.
5. Huerkamp M. J. and N. D. M. L. Lehner. 1994. Comparative effects of forced-air, individual cage ventilation, or an absorbent bedding additive on mouse isolator cage microenvironment. Contemp. Top. Lab. Anim. Sci. 33(2):58-61.
6. Perkins, S. E. and N. E. Lipman. 1996. Evaluation of microenvironmental conditions and noise generation in three individually ventilated rodent caging systems and static isolator cages. Contemp. Top. Lab. Anim. Sci. 35(2):61-65.
7. Hoglund, A. U. and A. Renstrom. 2001. Evaluation of individually ventilated cage systems for laboratory rodents: cage environment and animal health aspects. Lab Anim. 35(1):51-57.
8. Krohn, T. C. and A. K. Hansen. 2000. The effects of and tolerances for carbon dioxide in relation to recent developments in laboratory animal housing. Scand. J. Lab. Anim. Sci. 27:173-181.
9. Krohn, T. C. and A. K. Hansen. 2002. Carbon dioxide concentrations in unventilated IVC cages. Lab Anim. 36(2):209-212.
10. Hasegawa, M., Y. Kurabyashi, T. Ishii, et al. 1997. Intra-cage air change rate on forced-air-ventilated micro-isolation system-environment within cages: carbon dioxide and oxygen concentration. Exp. Anim. 46(4):251-257.
11. Clark, J. D., R. L. Baldwin, K. A. Bayne, et al. 1996. Guide for the care and use of laboratory animals, p. 25-27. National Research Council, National Academy Press, Washington, D.C.