-
1
-
-
0024328536
-
Altering the genome by homologous recombination
-
Capecchi, M. R. Altering the genome by homologous recombination. Science 244, 1283-1292 (1989).
-
(1989)
Science
, vol.244
, pp. 1283-1292
-
-
Capecchi, M.R.1
-
2
-
-
0033398982
-
Ten years of enhancer detection: Lessons from the fly
-
Bellen, H. J. Ten years of enhancer detection: Lessons from the fly. The Plant Cell 11, 2271-2281 (1999).
-
(1999)
The Plant Cell
, vol.11
, pp. 2271-2281
-
-
Bellen, H.J.1
-
3
-
-
0032499252
-
Disruption and sequence identification of 2,000 genes in mouse embryonic stem cells
-
Zambrowicz, B. P. et al. Disruption and sequence identification of 2,000 genes in mouse embryonic stem cells. Nature 392, 608-611 (1998).
-
(1998)
Nature
, vol.392
, pp. 608-611
-
-
Zambrowicz, B.P.1
-
4
-
-
0034425410
-
A systematic genome-wide phenotype-driven mutagenesis programme for gene function studies in the mouse
-
Nolan, P. M. et al. A systematic genome-wide phenotype-driven mutagenesis programme for gene function studies in the mouse. Nature Genet. 25, 440-443 (2000).
-
(2000)
Nature Genet.
, vol.25
, pp. 440-443
-
-
Nolan, P.M.1
-
5
-
-
0034425715
-
Genome wide large scale production of mutant mice by ENU mutagenesis
-
Hrabe de Angelis, M. et al. Genome wide large scale production of mutant mice by ENU mutagenesis. Nature Genet. 25, 444-447 (2000). References 4 and 5 describe the first large-scale ENU mutagenesis screens in the mouse.
-
(2000)
Nature Genet.
, vol.25
, pp. 444-447
-
-
Hrabe De Angelis, M.1
-
6
-
-
0031255352
-
SHIRPA, a proposed protocol for comprehensive phenotype assessment
-
Rogers, D. C. et al. SHIRPA, a proposed protocol for comprehensive phenotype assessment. Mamm. Genome 8, 711-713 (1997).
-
(1997)
Mamm. Genome
, vol.8
, pp. 711-713
-
-
Rogers, D.C.1
-
7
-
-
0013677535
-
Studies on spotting patterns. II. Genetic analysis of variegated spotting in the house mouse
-
Dunn, L. C. Studies on spotting patterns. II. Genetic analysis of variegated spotting in the house mouse. Genetics 22, 43-64 (1937).
-
(1937)
Genetics
, vol.22
, pp. 43-64
-
-
Dunn, L.C.1
-
8
-
-
0032919366
-
The Mouse Genome Database (MGD): Genetic and genomic information about the laboratory mouse. The Mouse Genome Database Group
-
Blake, J. A., Richardson, J. E., Davisson, M. T. & Eppig, J. T. The Mouse Genome Database (MGD): Genetic and genomic information about the laboratory mouse. The Mouse Genome Database Group. Nucleic Acids Res. 27, 95-98 (1999). This paper describes the features of the Mouse Genome Database (MGD).
-
(1999)
Nucleic Acids Res.
, vol.27
, pp. 95-98
-
-
Blake, J.A.1
Richardson, J.E.2
Davisson, M.T.3
Eppig, J.T.4
-
9
-
-
0001555958
-
Steel, a new dominant gene in the house mouse
-
Sarvella, P. A. & Russell, L. B. Steel, a new dominant gene in the house mouse. J. Hered. 47, 123-128 (1956).
-
(1956)
J. Hered.
, vol.47
, pp. 123-128
-
-
Sarvella, P.A.1
Russell, L.B.2
-
10
-
-
0028365880
-
PCR-amplification of simple sequence repeat variants from pooled DNA samples for rapidly mapping new mutations of the mouse
-
Taylor, B. A., Navin, A. & Phillips, S. J. PCR-amplification of simple sequence repeat variants from pooled DNA samples for rapidly mapping new mutations of the mouse. Genomics 21, 626-632 (1994).
-
(1994)
Genomics
, vol.21
, pp. 626-632
-
-
Taylor, B.A.1
Navin, A.2
Phillips, S.J.3
-
11
-
-
0346500972
-
-
(eds Jackson, I. J. & Abbott, C. M.) Oxford Univ. Press, Oxford
-
Taylor, B. A. in Mouse Genetics and Transgenics: A Practical Approach (eds Jackson, I. J. & Abbott, C. M.) 87-120 (Oxford Univ. Press, Oxford, 1999).
-
(1999)
Mouse Genetics and Transgenics: A Practical Approach
, pp. 87-120
-
-
Taylor, B.A.1
-
12
-
-
0034425606
-
The roads from phenotypic variation to gene discovery: Mutagenesis versus QTLs
-
Nadeau, J. H. & Frankel, W. N. The roads from phenotypic variation to gene discovery: mutagenesis versus QTLs. Nature Genet. 25, 381-384 (2000).
-
(2000)
Nature Genet.
, vol.25
, pp. 381-384
-
-
Nadeau, J.H.1
Frankel, W.N.2
-
14
-
-
0030796721
-
Reverse genetics by chemical mutagenesis in Caenorhabditis elegans
-
Jansen, G., Hazendonk, E., Thijssen, K. L. & Plasterk, R. Reverse genetics by chemical mutagenesis in Caenorhabditis elegans. Nature Genet. 17, 119-121 (1997).
-
(1997)
Nature Genet.
, vol.17
, pp. 119-121
-
-
Jansen, G.1
Hazendonk, E.2
Thijssen, K.L.3
Plasterk, R.4
-
15
-
-
0008125299
-
Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster I. Zygotic loci on the second chromosome
-
Nusslein-Volhard, C., Wieschaus, E. & Kluding, H. Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster I. Zygotic loci on the second chromosome. Roux's Archives Dev. Biol. 193, 267-282 (1984).
-
(1984)
Roux's Archives Dev. Biol.
, vol.193
, pp. 267-282
-
-
Nusslein-Volhard, C.1
Wieschaus, E.2
Kluding, H.3
-
16
-
-
34250136181
-
Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster III. Zygotic loci on the X-chromosome and fourth chromosome
-
Wieschaus, E., Nusslein-Volhard, C. & Jurgens, G. Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster III. Zygotic loci on the X-chromosome and fourth chromosome. Roux's Archives Dev. Biol. 193, 296-307 (1984).
-
(1984)
Roux's Archives Dev. Biol.
, vol.193
, pp. 296-307
-
-
Wieschaus, E.1
Nusslein-Volhard, C.2
Jurgens, G.3
-
17
-
-
34250134008
-
Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster II. Zygotic loci on the third chromosome
-
Jurgens, G., Wieschaus, E., Nusslein-Volhard, C. & Kluding, H. Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster II. Zygotic loci on the third chromosome. Roux's Archives Dev. Biol. 193, 283-295 (1984).
-
(1984)
Roux's Archives Dev. Biol.
, vol.193
, pp. 283-295
-
-
Jurgens, G.1
Wieschaus, E.2
Nusslein-Volhard, C.3
Kluding, H.4
-
18
-
-
0016730617
-
Isolation and characterization of sex-linked female-sterile mutants in Drosophila melanogaster
-
Gans, M., Audit, C. & Masson, M. Isolation and characterization of sex-linked female-sterile mutants in Drosophila melanogaster. Genetics 81, 683-704 (1975).
-
(1975)
Genetics
, vol.81
, pp. 683-704
-
-
Gans, M.1
Audit, C.2
Masson, M.3
-
19
-
-
0019133661
-
Mutations affecting segment number and polarity in Drosophila
-
Nusslein-Volhard, C. & Wieschaus, E. Mutations affecting segment number and polarity in Drosophila. Nature 287, 795-801 (1980).
-
(1980)
Nature
, vol.287
, pp. 795-801
-
-
Nusslein-Volhard, C.1
Wieschaus, E.2
-
20
-
-
0030598904
-
The role of the genome project in determining gene function: Insights from model organisms
-
Miklos, G. L. & Rubin, G. M. The role of the genome project in determining gene function: Insights from model organisms. Cell 86, 521-529 (1996).
-
(1996)
Cell
, vol.86
, pp. 521-529
-
-
Miklos, G.L.1
Rubin, G.M.2
-
21
-
-
12644303221
-
The identification of genes with unique and essential functions in the development of the zebrafish, Danio rerio
-
Haffter, P. et al. The identification of genes with unique and essential functions in the development of the zebrafish, Danio rerio. Development 123, 1-36 (1996).
-
(1996)
Development
, vol.123
, pp. 1-36
-
-
Haffter, P.1
-
22
-
-
12644268233
-
A genetic screen for mutations affecting embryogenesis in zebrafish
-
Driever, W. et al. A genetic screen for mutations affecting embryogenesis in zebrafish. Development 123, 37-46 (1996).
-
(1996)
Development
, vol.123
, pp. 37-46
-
-
Driever, W.1
-
23
-
-
18244431887
-
Vertebrate genome evolution and the zebrafish gene map
-
Postlethwait, J. H. et al. Vertebrate genome evolution and the zebrafish gene map. Nature Genet. 18, 345-349 (1998).
-
(1998)
Nature Genet.
, vol.18
, pp. 345-349
-
-
Postlethwait, J.H.1
-
24
-
-
0033569405
-
A large-scale insertional mutagenesis screen in zebrafish
-
Amsterdam, A. et al. A large-scale insertional mutagenesis screen in zebrafish. Genes Dev. 13, 2713-2724 (1999).
-
(1999)
Genes Dev.
, vol.13
, pp. 2713-2724
-
-
Amsterdam, A.1
-
25
-
-
0021733794
-
Hereditary joint disorder in progressive ankylosis (ank/ank) mice
-
Hakim, F. T. et al. Hereditary joint disorder in progressive ankylosis (ank/ank) mice, Arthritis Rheum. 27, 1411-1420 (1984).
-
(1984)
Arthritis Rheum.
, vol.27
, pp. 1411-1420
-
-
Hakim, F.T.1
-
26
-
-
0034647482
-
Role of the mouse ank gene in control of tissue calcification and arthritis
-
Ho, A. M., Johnson, M. D. & Kingsley, D. M. Role of the mouse ank gene in control of tissue calcification and arthritis. Science 289, 265-270 (2000).
-
(2000)
Science
, vol.289
, pp. 265-270
-
-
Ho, A.M.1
Johnson, M.D.2
Kingsley, D.M.3
-
27
-
-
0032943533
-
An action plan for mouse genomics
-
Battey, J., Jordan, E., Cox, D. & Dove, W. An action plan for mouse genomics. Nature Genet. 21, 73-75 (1999). This paper explains the rationale for the trans-NIH mouse Initiatives.
-
(1999)
Nature Genet.
, vol.21
, pp. 73-75
-
-
Battey, J.1
Jordan, E.2
Cox, D.3
Dove, W.4
-
28
-
-
0034237732
-
Mouse as the measure of man?
-
Denny, P. & Justice, M. J. Mouse as the measure of man? Trends Genet. 16, 283-287 (2000).
-
(2000)
Trends Genet.
, vol.16
, pp. 283-287
-
-
Denny, P.1
Justice, M.J.2
-
29
-
-
0034595496
-
Australian 'ranch' gears up to mass-produce mutant mice
-
Finkel, E. Australian 'ranch' gears up to mass-produce mutant mice. Science 288, 1572-1573 (2000).
-
(2000)
Science
, vol.288
, pp. 1572-1573
-
-
Finkel, E.1
-
30
-
-
0033152654
-
A system for rapid generation of coat color-tagged knockouts and defined chromosomal rearrangements in mice
-
Zheng, B., Mills, A. A. & Bradley, A. A system for rapid generation of coat color-tagged knockouts and defined chromosomal rearrangements in mice. Nucleic Acids Res. 27, 2354-2360 (1999).
-
(1999)
Nucleic Acids Res.
, vol.27
, pp. 2354-2360
-
-
Zheng, B.1
Mills, A.A.2
Bradley, A.3
-
31
-
-
0032813539
-
Engineering a balancer chromosome in the mouse
-
Zheng, B. et al. Engineering a balancer chromosome in the mouse. Nature Genet. 22, 375-378 (1999). A seminal paper that describes chromosomal engineering techniques to generate a coat-colour tagged balancer chromosome for genetic studies in the mouse.
-
(1999)
Nature Genet.
, vol.22
, pp. 375-378
-
-
Zheng, B.1
-
32
-
-
0034090650
-
Mouse mutants from chemically mutagenized embryonic stem cells
-
Munro, R. J. et al. Mouse mutants from chemically mutagenized embryonic stem cells. Nature Genet. 24, 318-321 (2000).
-
(2000)
Nature Genet.
, vol.24
, pp. 318-321
-
-
Munro, R.J.1
-
33
-
-
0034091810
-
Genotype-based screen for ENU-induced mutations in mouse embryonic stem cells
-
Chen, Y. et al. Genotype-based screen for ENU-induced mutations in mouse embryonic stem cells. Nature Genet. 24, 314-317 (2000). References 32 and 33 describe the use of point mutagens for gene-based screens in mouse embryonic stem cells.
-
(2000)
Nature Genet.
, vol.24
, pp. 314-317
-
-
Chen, Y.1
-
34
-
-
0033860049
-
Algorithms for mutant sorting: The need for phenotype vocabularies
-
Eppig, J. T. Algorithms for mutant sorting: The need for phenotype vocabularies. Mamm. Genome 11, 584-589 (2000).
-
(2000)
Mamm. Genome
, vol.11
, pp. 584-589
-
-
Eppig, J.T.1
-
35
-
-
0022369586
-
Dose-repetition increases the mutagenic effectiveness of N-ethyl-N-nitrosourea in mouse spermatogonia
-
Hitotsumachi, S., Carpenter, D. A. & Russell, W. L. Dose-repetition increases the mutagenic effectiveness of N-ethyl-N-nitrosourea in mouse spermatogonia. Proc. Natl Acad. Sci. USA 82, 6619-6621 (1985).
-
(1985)
Proc. Natl Acad. Sci. USA
, vol.82
, pp. 6619-6621
-
-
Hitotsumachi, S.1
Carpenter, D.A.2
Russell, W.L.3
-
36
-
-
0027295348
-
Mouse models of human phenylketonuria
-
Shedlovsky, A., McDonald, J. D., Symula, D. & Dove, W. F. Mouse models of human phenylketonuria. Genetics 134, 1205-1210 (1993).
-
(1993)
Genetics
, vol.134
, pp. 1205-1210
-
-
Shedlovsky, A.1
McDonald, J.D.2
Symula, D.3
Dove, W.F.4
-
37
-
-
0001996864
-
-
(eds Jackson, I. J. & Abbott, C. M.) Oxford Univ. Press, Oxford
-
Justice, M. J. in Mouse Genetics and Transgenics: A Practical Approach (eds Jackson, I. J. & Abbott, C. M.) 185-215 (Oxford Univ. Press, Oxford, 1999).
-
(1999)
Mouse Genetics and Transgenics: A Practical Approach
, pp. 185-215
-
-
Justice, M.J.1
-
38
-
-
0032837860
-
Mouse ENU mutagenesis
-
Justice, M. J., Noveroske, J. N., Weber, J. S., Zheng, B. & Bradley, A. Mouse ENU mutagenesis. Human Genet. 8, 1955-1963 (1999).
-
(1999)
Human Genet.
, vol.8
, pp. 1955-1963
-
-
Justice, M.J.1
Noveroske, J.N.2
Weber, J.S.3
Zheng, B.4
Bradley, A.5
|