Probing the acy1-binding pocket of aminoacylase-1

Biochemistry

Volumn 47, Issue 14, 2008, Pages 4266-4275

  Lindner, Holger A ^a   Alary, Alain ^a   Wilke, Marsha ^a   Sulea, Traian ^a  

^a NATIONAL RESEARCH COUNCIL CANADA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCATALYSTS; ENZYME ACTIVITY; HYDROLYSIS; TOPOLOGY;

CATALYTIC EFFICIENCY; RACEMIC RESOLUTION; SUBSTRATE SPECIFICITY;

BINDING SITES;

AMINO ACID DERIVATIVE; AMINOACYLASE; ISOLEUCINE; LEUCINE; THREONINE; AMIDASE; AMINOACYLASE I; METHIONINE;

ALPHA CHAIN; ARTICLE; BETA CHAIN; CATALYSIS; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME ENGINEERING; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; GENETIC CONSERVATION; HYDROLYSIS; METAL BINDING; MICHAELIS CONSTANT; MOLECULAR PROBE; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN STRUCTURE; QUANTITATIVE STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; ANIMAL; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; HUMAN; KINETICS; METABOLISM; MUTATION; PROTEIN TERTIARY STRUCTURE; SWINE;

BACTERIA (MICROORGANISMS); MAMMALIA; SUS;

AMIDOHYDROLASES; ANIMALS; BINDING SITES; HUMANS; KINETICS; METHIONINE; MODELS, MOLECULAR; MUTATION; PROTEIN STRUCTURE, TERTIARY; SUBSTRATE SPECIFICITY; SWINE;

EID: 41849115598     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi702156h     Document Type: Article

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