MTD-PLS: A PLS-based variant of the MTD method. 2. Mapping ligand-receptor interactions. Enzymatic acetic acid esters hydrolysis

Journal of Chemical Information and Computer Sciences

Volumn 42, Issue 4, 2002, Pages 841-846

  Kurunczi, Ludovic ^a   Olah, Marius ^b   Oprea, Tudor I ^b,c   Bologa, Cristian ^b   Simon, Zeno ^b  

^a VICTOR BABES UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^b WEST UNIVERSITY OF TIMISOARA   (Romania)

^c ASTRAZENECA R AND D   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID; ENZYMES; HYDROLYSIS; HYDROPHOBICITY; STATISTICAL METHODS; SYNTHESIS (CHEMICAL);

LIGANDS;

ESTERS;

ACETIC ACID DERIVATIVE; ACETYLCHOLINESTERASE; DRUG RECEPTOR; LIGAND;

ANIMAL; ARTICLE; CHEMICAL MODEL; CHEMISTRY; COMPARATIVE STUDY; COMPUTER SIMULATION; ELECTRICITY; ENZYME SPECIFICITY; HYDROLYSIS; IN VITRO STUDY; KINETICS; METABOLISM; QUANTITATIVE STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY;

ACETATES; ACETYLCHOLINESTERASE; ANIMALS; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; ELECTROSTATICS; HYDROLYSIS; KINETICS; LIGANDS; MODELS, CHEMICAL; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RECEPTORS, DRUG; SUBSTRATE SPECIFICITY;

EID: 0036628551     PISSN: 00952338     EISSN: None     Source Type: Journal    
DOI: 10.1021/ci010124a     Document Type: Article

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