-
1
-
-
0033624575
-
The common PPARγ Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes
-
Altshuler, D., Hirschhorn, J.N., Klannemark, M., Lindgren, C.M., Vohl, M.C., Nemesh, J., Lane, C.R., Schaffner, S.F., Bolk, S., Brewer, C., et al. 2000. The common PPARγ Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes. Nat. Genet. 26: 76-80.
-
(2000)
Nat. Genet
, vol.26
, pp. 76-80
-
-
Altshuler, D.1
Hirschhorn, J.N.2
Klannemark, M.3
Lindgren, C.M.4
Vohl, M.C.5
Nemesh, J.6
Lane, C.R.7
Schaffner, S.F.8
Bolk, S.9
Brewer, C.10
-
2
-
-
79959524146
-
A haplotype map of the human genome
-
Altshuler, D., Brooks, L.D., Chakravarti, A., Collins, F.S., Daly, M.J., and Donnelly, P. 2005. A haplotype map of the human genome. Nature 437: 1299-1320.
-
(2005)
Nature
, vol.437
, pp. 1299-1320
-
-
Altshuler, D.1
Brooks, L.D.2
Chakravarti, A.3
Collins, F.S.4
Daly, M.J.5
Donnelly, P.6
-
3
-
-
0001677717
-
Controlling the false discovery rate: A practical and powerful approach to multiple testing
-
Benjamini, Y. and Hochberg, Y. 1995. Controlling the false discovery rate: A practical and powerful approach to multiple testing. J. R. Stat. Soc. Ser. B 57: 289-300.
-
(1995)
J. R. Stat. Soc. Ser. B
, vol.57
, pp. 289-300
-
-
Benjamini, Y.1
Hochberg, Y.2
-
4
-
-
0037177625
-
Genetic dissection of transcriptional regulation in budding yeast
-
Brem, R.B., Yvert, G., Clinton, R., and Kruglyak, L. 2002. Genetic dissection of transcriptional regulation in budding yeast. Science 296: 752-755.
-
(2002)
Science
, vol.296
, pp. 752-755
-
-
Brem, R.B.1
Yvert, G.2
Clinton, R.3
Kruglyak, L.4
-
5
-
-
34248154742
-
Association studies of BMI and type 2 diabetes in the neuropeptide Y pathway: A possible role for NPY2R as a candidate gene for type 2 diabetes in men
-
Campbell, C.D., Lyon, H.N., Nemesh, J., Drake, J.A., Tuomi, T., Gaudet, D., Zhu, X., Cooper, R.S., Ardlie, K.G., Groop, L.C., et al. 2007. Association studies of BMI and type 2 diabetes in the neuropeptide Y pathway: A possible role for NPY2R as a candidate gene for type 2 diabetes in men. Diabetes 56: 1460-1467.
-
(2007)
Diabetes
, vol.56
, pp. 1460-1467
-
-
Campbell, C.D.1
Lyon, H.N.2
Nemesh, J.3
Drake, J.A.4
Tuomi, T.5
Gaudet, D.6
Zhu, X.7
Cooper, R.S.8
Ardlie, K.G.9
Groop, L.C.10
-
6
-
-
0036899513
-
The genetics of variation in gene expression
-
Cheung, V.G. and Spielman, R.S. 2002. The genetics of variation in gene expression. Nat. Genet. (Suppl.) 32: 522-525.
-
(2002)
Nat. Genet. (Suppl.)
, vol.32
, pp. 522-525
-
-
Cheung, V.G.1
Spielman, R.S.2
-
7
-
-
0037370311
-
Natural variation in human gene expression assessed in lymphoblastoid cells
-
Cheung, V.G., Conlin, L.K., Weber, T.M., Arcaro, M., Jen, K.Y., Morley, M., and Spielman, R.S. 2003. Natural variation in human gene expression assessed in lymphoblastoid cells. Nat. Genet. 33: 422-425.
-
(2003)
Nat. Genet
, vol.33
, pp. 422-425
-
-
Cheung, V.G.1
Conlin, L.K.2
Weber, T.M.3
Arcaro, M.4
Jen, K.Y.5
Morley, M.6
Spielman, R.S.7
-
8
-
-
0036843938
-
Detection of regulatory variation in mouse genes
-
Cowles, C.R., Hirschhorn, J.N., Altshuler, D., and Lander, E.S. 2002. Detection of regulatory variation in mouse genes. Nat. Genet. 32: 432-437.
-
(2002)
Nat. Genet
, vol.32
, pp. 432-437
-
-
Cowles, C.R.1
Hirschhorn, J.N.2
Altshuler, D.3
Lander, E.S.4
-
9
-
-
33845340501
-
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene
-
Duerr, R.H., Taylor, K.D., Brant, S.R., Rioux, J.D., Silverberg, M.S., Daly, M.J., Steinhart, A.H., Abraham, C., Regueiro, M., Griffiths, A., et al. 2006. A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science 314: 1461-1463.
-
(2006)
Science
, vol.314
, pp. 1461-1463
-
-
Duerr, R.H.1
Taylor, K.D.2
Brant, S.R.3
Rioux, J.D.4
Silverberg, M.S.5
Daly, M.J.6
Steinhart, A.H.7
Abraham, C.8
Regueiro, M.9
Griffiths, A.10
-
10
-
-
2342561802
-
Haplotype structure and genotype-phenotype correlations of the sulfonylurea receptor and the islet ATP-sensitive potassium channel gene region
-
Florez, J.C., Burtt, N., de Bakker, P.I., Almgren, P., Tuomi, T., Holmkvist, J., Gaudet, D., Hudson, T.J., Schaffner, S.F., Daly, M.J., et al. 2004. Haplotype structure and genotype-phenotype correlations of the sulfonylurea receptor and the islet ATP-sensitive potassium channel gene region. Diabetes 53: 1360-1368.
-
(2004)
Diabetes
, vol.53
, pp. 1360-1368
-
-
Florez, J.C.1
Burtt, N.2
de Bakker, P.I.3
Almgren, P.4
Tuomi, T.5
Holmkvist, J.6
Gaudet, D.7
Hudson, T.J.8
Schaffner, S.F.9
Daly, M.J.10
-
11
-
-
18444369013
-
The structure of haplotype blocks in the human genome
-
Gabriel, S.B., Schaffner, S.F., Nguyen, H., Moore, J.M., Roy, J., Blumenstiel, B., Higgins, J., DeFelice, M., Lochner, A., Faggart, M., et al. 2002. The structure of haplotype blocks in the human genome. Science 296: 2225-2229.
-
(2002)
Science
, vol.296
, pp. 2225-2229
-
-
Gabriel, S.B.1
Schaffner, S.F.2
Nguyen, H.3
Moore, J.M.4
Roy, J.5
Blumenstiel, B.6
Higgins, J.7
DeFelice, M.8
Lochner, A.9
Faggart, M.10
-
12
-
-
33646368404
-
A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus
-
Graham, R.R., Kozyrev, S.V., Baechler, E.C., Reddy, M.V., Plenge, R.M., Bauer, J.W., Ortmann, W.A., Koeuth, T., Gonzalez Escribano, M.F., Pons-Estel, B., et al. 2006. A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus. Nat. Genet. 38: 550-555.
-
(2006)
Nat. Genet
, vol.38
, pp. 550-555
-
-
Graham, R.R.1
Kozyrev, S.V.2
Baechler, E.C.3
Reddy, M.V.4
Plenge, R.M.5
Bauer, J.W.6
Ortmann, W.A.7
Koeuth, T.8
Gonzalez Escribano, M.F.9
Pons-Estel, B.10
-
13
-
-
34249860408
-
Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus
-
Graham, R.R., Kyogoku, C., Sigurdsson, S., Vlasova, I.A., Davies, L.R., Baechler, E.C., Plenge, R.M., Koeuth, T., Ortmann, W.A., Hom, G., et al. 2007a. Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus. Proc. Natl. Acad. Sci. 104: 6758-6763.
-
(2007)
Proc. Natl. Acad. Sci
, vol.104
, pp. 6758-6763
-
-
Graham, R.R.1
Kyogoku, C.2
Sigurdsson, S.3
Vlasova, I.A.4
Davies, L.R.5
Baechler, E.C.6
Plenge, R.M.7
Koeuth, T.8
Ortmann, W.A.9
Hom, G.10
-
14
-
-
34247125683
-
Association of IRF5 in UK SLE families identifies a variant involved in polyadenylation
-
Graham, D.S., Manku, H., Wagner, S., Reid, J., Timms, K., Gutin, A., Lanchbury, J.S., and Vyse, T.J. 2007b. Association of IRF5 in UK SLE families identifies a variant involved in polyadenylation. Hum. Mol. Genet. 16: 579-591.
-
(2007)
Hum. Mol. Genet
, vol.16
, pp. 579-591
-
-
Graham, D.S.1
Manku, H.2
Wagner, S.3
Reid, J.4
Timms, K.5
Gutin, A.6
Lanchbury, J.S.7
Vyse, T.J.8
-
15
-
-
32544451924
-
Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes
-
Grant, S.F., Thorleifsson, G., Reynisdottir, I., Benediktsson, R., Manolescu, A., Sainz, J., Helgason, A., Stefansson, H., Emilsson, V., Helgadottir, A., et al. 2006. Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat. Genet. 38: 320-323.
-
(2006)
Nat. Genet
, vol.38
, pp. 320-323
-
-
Grant, S.F.1
Thorleifsson, G.2
Reynisdottir, I.3
Benediktsson, R.4
Manolescu, A.5
Sainz, J.6
Helgason, A.7
Stefansson, H.8
Emilsson, V.9
Helgadottir, A.10
-
16
-
-
0037338098
-
Imprinting regulation of the murine Meg1/Grb10 and human GRB10 genes; roles of brain-specific promoters and mouse-specific CTCF-binding sites
-
Hikichi, T., Kohda, T., Kaneko-Ishino, T., and Ishino, F. 2003. Imprinting regulation of the murine Meg1/Grb10 and human GRB10 genes; roles of brain-specific promoters and mouse-specific CTCF-binding sites. Nucleic Acids Res. 31: 1398-1406.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 1398-1406
-
-
Hikichi, T.1
Kohda, T.2
Kaneko-Ishino, T.3
Ishino, F.4
-
17
-
-
20244380171
-
Complement factor H polymorphism in age-related macular degeneration
-
Klein, R.J., Zeiss, C., Chew, E.Y., Tsai, J.Y., Sackler, R.S., Haynes, C., Henning, A.K., SanGiovanni, J.P., Mane, S.M., Mayne, S.T., et al. 2005. Complement factor H polymorphism in age-related macular degeneration. Science 308: 385-389.
-
(2005)
Science
, vol.308
, pp. 385-389
-
-
Klein, R.J.1
Zeiss, C.2
Chew, E.Y.3
Tsai, J.Y.4
Sackler, R.S.5
Haynes, C.6
Henning, A.K.7
SanGiovanni, J.P.8
Mane, S.M.9
Mayne, S.T.10
-
18
-
-
1242271304
-
Allele-specific gene expression uncovered
-
Knight, J.C. 2004. Allele-specific gene expression uncovered. Trends Genet. 20: 113-116.
-
(2004)
Trends Genet
, vol.20
, pp. 113-116
-
-
Knight, J.C.1
-
19
-
-
0012789869
-
Allelic variation in gene expression is common in the human genome
-
Lo, H.S., Wang, Z., Hu, Y., Yang, H.H., Gere, S., Buetow, K.H., and Lee, M.P. 2003. Allelic variation in gene expression is common in the human genome. Genome Res. 13: 1855-1862.
-
(2003)
Genome Res
, vol.13
, pp. 1855-1862
-
-
Lo, H.S.1
Wang, Z.2
Hu, Y.3
Yang, H.H.4
Gere, S.5
Buetow, K.H.6
Lee, M.P.7
-
20
-
-
34249996115
-
A common allele on chromosome 9 associated with coronary heart disease
-
McPherson, R., Pertsemlidis, A., Kavaslar, N., Stewart, A., Roberts, R., Cox, D.R., Hinds, D.A., Pennacchio, L.A., Tybjaerg-Hansen, A., Folsom, A.R., et al. 2007. A common allele on chromosome 9 associated with coronary heart disease. Science 316: 1488-1491.
-
(2007)
Science
, vol.316
, pp. 1488-1491
-
-
McPherson, R.1
Pertsemlidis, A.2
Kavaslar, N.3
Stewart, A.4
Roberts, R.5
Cox, D.R.6
Hinds, D.A.7
Pennacchio, L.A.8
Tybjaerg-Hansen, A.9
Folsom, A.R.10
-
21
-
-
8844244726
-
Genetic inheritance of gene expression in human cell lines
-
Monks, S.A., Leonardson, A., Zhu, H., Cundiff, P., Pietrusiak, P., Edwards, S., Phillips, J.W., Sachs, A., and Schadt, E.E. 2004. Genetic inheritance of gene expression in human cell lines. Am. J. Hum. Genet. 75: 1094-1105.
-
(2004)
Am. J. Hum. Genet
, vol.75
, pp. 1094-1105
-
-
Monks, S.A.1
Leonardson, A.2
Zhu, H.3
Cundiff, P.4
Pietrusiak, P.5
Edwards, S.6
Phillips, J.W.7
Sachs, A.8
Schadt, E.E.9
-
22
-
-
4043128071
-
Genetic analysis of genome-wide variation in human gene expression
-
Morley, M., Molony, C.M., Weber, T.M., Devlin, J.L., Ewens, K.G., Spielman, R.S., and Cheung, V.G. 2004. Genetic analysis of genome-wide variation in human gene expression. Nature 430: 743-747.
-
(2004)
Nature
, vol.430
, pp. 743-747
-
-
Morley, M.1
Molony, C.M.2
Weber, T.M.3
Devlin, J.L.4
Ewens, K.G.5
Spielman, R.S.6
Cheung, V.G.7
-
23
-
-
33644662511
-
Analysis of allelic differential expression in human white blood cells
-
Pant, P.V., Tao, H., Beilharz, E.J., Ballinger, D.G., Cox, D.R., and Frazer, K.A. 2006. Analysis of allelic differential expression in human white blood cells. Genome Res. 16: 331-339.
-
(2006)
Genome Res
, vol.16
, pp. 331-339
-
-
Pant, P.V.1
Tao, H.2
Beilharz, E.J.3
Ballinger, D.G.4
Cox, D.R.5
Frazer, K.A.6
-
24
-
-
10744224159
-
A survey of genetic and epigenetic variation affecting human gene expression
-
Pastinen, T., Sladek, R., Gurd, S., Sammak, A., Ge, B., Lepage, P., Lavergne, K., Villeneuve, A., Gaudin, T., Brandstrom, H., et al. 2004. A survey of genetic and epigenetic variation affecting human gene expression. Physiol. Genomics 16: 184-193.
-
(2004)
Physiol. Genomics
, vol.16
, pp. 184-193
-
-
Pastinen, T.1
Sladek, R.2
Gurd, S.3
Sammak, A.4
Ge, B.5
Lepage, P.6
Lavergne, K.7
Villeneuve, A.8
Gaudin, T.9
Brandstrom, H.10
-
25
-
-
40149096663
-
-
Ronald, J. and Akey, J.M. 2007. The evolution of gene expression QTL in Saccharomyces cerevisiae. PLoS One 2: e678. doi: 10.1371/journal.pone.0000678.
-
Ronald, J. and Akey, J.M. 2007. The evolution of gene expression QTL in Saccharomyces cerevisiae. PLoS One 2: e678. doi: 10.1371/journal.pone.0000678.
-
-
-
-
26
-
-
34249888775
-
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
-
Saxena, R., Voight, B.F., Lyssenko, V., Burtt, N.P., de Bakker, P.I., Chen, H., Roix, J.J., Kathiresan, S., Hirschhorn, J.N., Daly, M.J., et al. 2007. Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science 316: 1331-1336.
-
(2007)
Science
, vol.316
, pp. 1331-1336
-
-
Saxena, R.1
Voight, B.F.2
Lyssenko, V.3
Burtt, N.P.4
de Bakker, P.I.5
Chen, H.6
Roix, J.J.7
Kathiresan, S.8
Hirschhorn, J.N.9
Daly, M.J.10
-
27
-
-
0037456823
-
Genetics of gene expression surveyed in maize, mouse and man
-
Schadt, E.E., Monks, S.A., Drake, T.A., Lusis, A.J., Che, N., Colinayo, V., Ruff, T.G., Milligan, S.B., Lamb, J.R., Cavet, G., et al. 2003. Genetics of gene expression surveyed in maize, mouse and man. Nature 422: 297-302.
-
(2003)
Nature
, vol.422
, pp. 297-302
-
-
Schadt, E.E.1
Monks, S.A.2
Drake, T.A.3
Lusis, A.J.4
Che, N.5
Colinayo, V.6
Ruff, T.G.7
Milligan, S.B.8
Lamb, J.R.9
Cavet, G.10
-
28
-
-
33847176604
-
A genome-wide association study identifies novel risk loci for type 2 diabetes
-
Sladek, R., Rocheleau, G., Rung, J., Dina, C., Shen, L., Serre, D., Boutin, P., Vincent, D., Belisle, A., Hadjadj, S., et al. 2007. A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature 445: 881-885.
-
(2007)
Nature
, vol.445
, pp. 881-885
-
-
Sladek, R.1
Rocheleau, G.2
Rung, J.3
Dina, C.4
Shen, L.5
Serre, D.6
Boutin, P.7
Vincent, D.8
Belisle, A.9
Hadjadj, S.10
-
29
-
-
0037648405
-
Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease
-
Ueda, H., Howson, J.M., Esposito, L., Heward, J., Snook, H., Chamberlain, G., Rainbow, D.B., Hunter, K.M., Smith, A.N., Di Genova, G., et al. 2003. Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease. Nature 423: 506-511.
-
(2003)
Nature
, vol.423
, pp. 506-511
-
-
Ueda, H.1
Howson, J.M.2
Esposito, L.3
Heward, J.4
Snook, H.5
Chamberlain, G.6
Rainbow, D.B.7
Hunter, K.M.8
Smith, A.N.9
Di Genova, G.10
-
30
-
-
0037119584
-
Allelic variation in human gene expression
-
Yan, H., Yuan, W., Velculescu, V.E., Vogelstein, B., and Kinzler, K.W. 2002. Allelic variation in human gene expression. Science 297: 1143.
-
(2002)
Science
, vol.297
, pp. 1143
-
-
Yan, H.1
Yuan, W.2
Velculescu, V.E.3
Vogelstein, B.4
Kinzler, K.W.5
-
31
-
-
33746681910
-
Tissue-specific expression and regulation of sexually dimorphic genes in mice
-
Yang, X., Schadt, E.E., Wang, S., Wang, H., Arnold, A.P., Ingram-Drake, L., Drake, T.A., and Lusis, A.J. 2006. Tissue-specific expression and regulation of sexually dimorphic genes in mice. Genome Res. 16: 995-1004.
-
(2006)
Genome Res
, vol.16
, pp. 995-1004
-
-
Yang, X.1
Schadt, E.E.2
Wang, S.3
Wang, H.4
Arnold, A.P.5
Ingram-Drake, L.6
Drake, T.A.7
Lusis, A.J.8
-
32
-
-
0042856391
-
Trans-acting regulatory variation in Saccharomyces cerevisiae and the role of transcription factors
-
Yvert, G., Brem, R.B., Whittle, J., Akey, J.M., Foss, E., Smith, E.N., Mackelprang, R., and Kruglyak, L. 2003. Trans-acting regulatory variation in Saccharomyces cerevisiae and the role of transcription factors. Nat. Genet. 35: 57-64.
-
(2003)
Nat. Genet
, vol.35
, pp. 57-64
-
-
Yvert, G.1
Brem, R.B.2
Whittle, J.3
Akey, J.M.4
Foss, E.5
Smith, E.N.6
Mackelprang, R.7
Kruglyak, L.8
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