Pharmacophore-based predictive model generation for potent antimalarials targeting haem detoxification pathway

Medicinal Chemistry Research

Volumn 16, Issue 5, 2007, Pages 213-229

  Acharya, Badri Narayan ^a   Kaushik, Mahabir Parshad ^a  

^a DEFENCE RESEARCH AND DEVELOPMENT ESTABLISHMENT   (India)

Author keywords

Haem detoxification; Malaria; Pharmacophore; Plasmodium falciparum; Predictive model

Indexed keywords

7 CHLORO 4 HYDROXYANILINOQUINOLINE; AMODIAQUINE; AMOPYROQUINE; ANTIMALARIAL AGENT; BIDESAMODIAQUINE; BIDESETHYLCHLOROQUINE; CHLOROQUINE; CHLOROQUINE PYROLIDINYL; CINCHONIDINE; CINCHONINE; DEETHYLAMODIAQUINE; DEHYDROXYFLUOROTEBAQUINE; DEHYDROXYTEBAQUINE; HALOFANTRINE; HEME; MEFLOQUINE; MEPACRINE; MONODESETHYLCHLOROQUINE; N TERT BUTYLAMODIAQUINE; PYRIDINE DERIVATIVE; PYRONARIDINE; QUINIDINE; QUININE; TEBAQUINE; UNCLASSIFIED DRUG;

ARTICLE; DRUG ACTIVITY; DRUG DETOXIFICATION; DRUG POTENCY; DRUG STRUCTURE; DRUG TARGETING; FISHER EXACT TEST; MOLECULAR MODEL; NONHUMAN; PHARMACOPHORE; PLASMODIUM FALCIPARUM; POLYMERIZATION; PREDICTION;

EID: 41649116099     PISSN: 10542523     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00044-007-9025-8     Document Type: Article

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