-
1
-
-
17844373810
-
7G methyltransferase Trm8p/Trm82p: Evidence linking activity to growth phenotype and implicating Trm82p in maintaining levels of active Trm8p
-
7G methyltransferase Trm8p/Trm82p: Evidence linking activity to growth phenotype and implicating Trm82p in maintaining levels of active Trm8p. RNA 11: 821-830.
-
(2005)
RNA
, vol.11
, pp. 821-830
-
-
Alexandrov, A.1
Grayhack, E.J.2
Phizicky, E.M.3
-
2
-
-
29544450711
-
Rapid tRNA decay can result from lack of nonessential modifications
-
Alexandrov, A., Chernyakov, I., Gu, W., Hiley, S.L., Hughes, T.R., Grayhack, E.J., and Phizicky, E.M. 2006. Rapid tRNA decay can result from lack of nonessential modifications. Mol. Cell 21: 144-145.
-
(2006)
Mol. Cell
, vol.21
, pp. 144-145
-
-
Alexandrov, A.1
Chernyakov, I.2
Gu, W.3
Hiley, S.L.4
Hughes, T.R.5
Grayhack, E.J.6
Phizicky, E.M.7
-
3
-
-
0034043398
-
Rrp8 is a yeast nucleolar protein functionally linked to Gar1p and involved in pre-rRNA cleavage at site A2
-
Antonelli-Bousquet, C., Vanrobays, E., Gelugne, J.-P., Caizergues-Ferrer, M., and Henry, Y. 2000. Rrp8 is a yeast nucleolar protein functionally linked to Gar1p and involved in pre-rRNA cleavage at site A2. RNA 6: 826-843.
-
(2000)
RNA
, vol.6
, pp. 826-843
-
-
Antonelli-Bousquet, C.1
Vanrobays, E.2
Gelugne, J.-P.3
Caizergues-Ferrer, M.4
Henry, Y.5
-
4
-
-
0034602703
-
Competition between a sterol biosynthetic enzyme and tRNA modification in addition to changes in the protein synthesis machinery causes altered nonsense suppression
-
Benko, A.L., Vaduva, G., Martin, N.C., and Hopper, A.K. 2000. Competition between a sterol biosynthetic enzyme and tRNA modification in addition to changes in the protein synthesis machinery causes altered nonsense suppression. Proc. Natl. Acad. Sci. 97: 61-66.
-
(2000)
Proc. Natl. Acad. Sci
, vol.97
, pp. 61-66
-
-
Benko, A.L.1
Vaduva, G.2
Martin, N.C.3
Hopper, A.K.4
-
5
-
-
18844407538
-
Mechanisms of haploinsufficiency revealed by genome-wide profiling in yeast
-
Deutschbauer, A.M., Jaramillo, D.F., Proctor, M., Kumm, J., Hillenmeyer, M.E., Davis, R.W., Nislow, C., and Giaever, G. 2005. Mechanisms of haploinsufficiency revealed by genome-wide profiling in yeast. Genetics 169: 1915-1925.
-
(2005)
Genetics
, vol.169
, pp. 1915-1925
-
-
Deutschbauer, A.M.1
Jaramillo, D.F.2
Proctor, M.3
Kumm, J.4
Hillenmeyer, M.E.5
Davis, R.W.6
Nislow, C.7
Giaever, G.8
-
6
-
-
0023084849
-
Isolation and characterization of MOD5, a gene required for isopentenylation of cytoplasmic and mitochondrial tRNAs of Saccharomyces cerevisiae
-
Dihanich, M.E., Najarian, D., Clark, R., Gillman, E.C., Martin, N.C., and Hopper, A.K. 1987. Isolation and characterization of MOD5, a gene required for isopentenylation of cytoplasmic and mitochondrial tRNAs of Saccharomyces cerevisiae. Mol. Cell. Biol. 7: 177-184.
-
(1987)
Mol. Cell. Biol
, vol.7
, pp. 177-184
-
-
Dihanich, M.E.1
Najarian, D.2
Clark, R.3
Gillman, E.C.4
Martin, N.C.5
Hopper, A.K.6
-
7
-
-
0034659266
-
A putative ubiquitin ligase required for efficient mRNA export differentially affects hnRNP transport
-
Duncan, K., Umen, J.G., and Guthrie, C. 2000. A putative ubiquitin ligase required for efficient mRNA export differentially affects hnRNP transport. Curr. Biol. 10: 687-696.
-
(2000)
Curr. Biol
, vol.10
, pp. 687-696
-
-
Duncan, K.1
Umen, J.G.2
Guthrie, C.3
-
8
-
-
10044286102
-
5-Fluorouracil enhances exosome-dependent accumulation of polyadenylated rRNAs
-
Fang, F., Hoskins, J., and Butler, J.S. 2004. 5-Fluorouracil enhances exosome-dependent accumulation of polyadenylated rRNAs. Mol. Cell. Biol. 24: 10766-10776.
-
(2004)
Mol. Cell. Biol
, vol.24
, pp. 10766-10776
-
-
Fang, F.1
Hoskins, J.2
Butler, J.S.3
-
9
-
-
0019978251
-
Loss of tRNA 5-methyluridine methyltransferases and pseudouridine synthase activities in 5-fluorouracil and 1-(tetrahydro-2-furanyl)-5-fluorouracil (ftorafur)-treated Escherichia coli
-
Frendewey, D.A., Kladianos, D.M., Moore, V.G., and Kaiser, I.I. 1982. Loss of tRNA 5-methyluridine methyltransferases and pseudouridine synthase activities in 5-fluorouracil and 1-(tetrahydro-2-furanyl)-5-fluorouracil (ftorafur)-treated Escherichia coli. Biochim. Biophys. Acta 697: 31-40.
-
(1982)
Biochim. Biophys. Acta
, vol.697
, pp. 31-40
-
-
Frendewey, D.A.1
Kladianos, D.M.2
Moore, V.G.3
Kaiser, I.I.4
-
10
-
-
9144268287
-
Chemogenomic profiling: Identifying the functional interactions of small molecules in yeast
-
Giaever, G., Flaherty, P., Kumm, J., Proctor, M., Nislow, C., Jaramillo, D.F., Chu, A.M., Jordan, M.I., Arkin, A.P., and Davis, R.W. 2004. Chemogenomic profiling: Identifying the functional interactions of small molecules in yeast. Proc. Natl. Acad. Sci. 101: 793-798.
-
(2004)
Proc. Natl. Acad. Sci
, vol.101
, pp. 793-798
-
-
Giaever, G.1
Flaherty, P.2
Kumm, J.3
Proctor, M.4
Nislow, C.5
Jaramillo, D.F.6
Chu, A.M.7
Jordan, M.I.8
Arkin, A.P.9
Davis, R.W.10
-
11
-
-
0035824521
-
Pus1p-dependent tRNA pseudouridinylation becomes essential when tRNA biogenesis is compromised in yeast
-
Grosshans, H., Lecointe, F., Grosjean, H., Hurt, E., and Simos, G. 2001. Pus1p-dependent tRNA pseudouridinylation becomes essential when tRNA biogenesis is compromised in yeast. J. Biol. Chem. 276: 46333-46339.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 46333-46339
-
-
Grosshans, H.1
Lecointe, F.2
Grosjean, H.3
Hurt, E.4
Simos, G.5
-
12
-
-
0026865946
-
RNA-directed actions of 5-fluorouridine in hemin stimulated K-562 erythroleukemia cells
-
Heimer, R. and Sartorelli, A.C. 1992. RNA-directed actions of 5-fluorouridine in hemin stimulated K-562 erythroleukemia cells. Cancer Biochem. Biophys. 12: 221-239.
-
(1992)
Cancer Biochem. Biophys
, vol.12
, pp. 221-239
-
-
Heimer, R.1
Sartorelli, A.C.2
-
13
-
-
0037439213
-
tRNA transfers to the limelight
-
Hopper, A.K. and Phizicky, E.M. 2003. tRNA transfers to the limelight. Genes & Dev. 17: 162-180.
-
(2003)
Genes & Dev
, vol.17
, pp. 162-180
-
-
Hopper, A.K.1
Phizicky, E.M.2
-
14
-
-
0020064025
-
Defects in modification of cytoplasmic and mitochondrial transfer RNAs are caused by single nuclear mutations
-
Hopper, A.K., Furukawa, A.H., Pham, H.D., and Martin, N.C. 1982. Defects in modification of cytoplasmic and mitochondrial transfer RNAs are caused by single nuclear mutations. Cell 28: 543-550.
-
(1982)
Cell
, vol.28
, pp. 543-550
-
-
Hopper, A.K.1
Furukawa, A.H.2
Pham, H.D.3
Martin, N.C.4
-
15
-
-
0032488657
-
A conserved aspartate of tRNA pseudouridine synthase is essential for activity and a probable nucleophilic catalyst
-
Huang, L., Pookanjanatavip, M., Gu, X., and Santi, D.V. 1998. A conserved aspartate of tRNA pseudouridine synthase is essential for activity and a probable nucleophilic catalyst. Biochemistry 37: 344-351.
-
(1998)
Biochemistry
, vol.37
, pp. 344-351
-
-
Huang, L.1
Pookanjanatavip, M.2
Gu, X.3
Santi, D.V.4
-
16
-
-
15444371415
-
An early step in wobble uridine tRNA modification requires the Elongator complex
-
Huang, B., Johanson, M.J., and Bystrom, A.S. 2005. An early step in wobble uridine tRNA modification requires the Elongator complex. RNA 11: 424-436.
-
(2005)
RNA
, vol.11
, pp. 424-436
-
-
Huang, B.1
Johanson, M.J.2
Bystrom, A.S.3
-
17
-
-
0035836765
-
A comprehensive two-hybrid analysis to explore the yeast protein interactome
-
Ito, T., Chiba, T., Ozawa, R., Yoshida, M., Hattori, M., and Sakaki, Y. 2001. A comprehensive two-hybrid analysis to explore the yeast protein interactome. Proc. Natl. Acad. Sci. 98: 4569-4574.
-
(2001)
Proc. Natl. Acad. Sci
, vol.98
, pp. 4569-4574
-
-
Ito, T.1
Chiba, T.2
Ozawa, R.3
Yoshida, M.4
Hattori, M.5
Sakaki, Y.6
-
21
-
-
0018886329
-
Effects of 5-fluorouracil on the formation of modified nucleosides in yeast transfer RNA
-
Johnson, J.D., Kaiser, I.I., and Horowitz, J. 1980. Effects of 5-fluorouracil on the formation of modified nucleosides in yeast transfer RNA. Biochim. Biophys. Acta 607: 285-294.
-
(1980)
Biochim. Biophys. Acta
, vol.607
, pp. 285-294
-
-
Johnson, J.D.1
Kaiser, I.I.2
Horowitz, J.3
-
22
-
-
0025738284
-
Increased cytotoxicity of low-dose, long-duration exposure to 5-fluorouracil of V-79 cells with hyperthermia
-
Kido, Y., Kuwano, H., Maehara, Y., Mori, M., Matsuoka, H., and Sugimachi, K. 1991. Increased cytotoxicity of low-dose, long-duration exposure to 5-fluorouracil of V-79 cells with hyperthermia. Cancer Chemother. Pharmacol. 28: 251-254.
-
(1991)
Cancer Chemother. Pharmacol
, vol.28
, pp. 251-254
-
-
Kido, Y.1
Kuwano, H.2
Maehara, Y.3
Mori, M.4
Matsuoka, H.5
Sugimachi, K.6
-
23
-
-
13444309083
-
Chemoradiotherapy combined with intracavitary hyperthermia for anal cancer: Feasibility and long-term results from a phase II randomized trial
-
Kouloulias, V., Plataniotis, G., Kouvaris, J., Dardoufas, C., Gennatas, C., Uzunoglu, N., Papavasiliou, C., and Vlahos, L. 2005. Chemoradiotherapy combined with intracavitary hyperthermia for anal cancer: Feasibility and long-term results from a phase II randomized trial. Am. J. Clin. Oncol. 28: 91-99.
-
(2005)
Am. J. Clin. Oncol
, vol.28
, pp. 91-99
-
-
Kouloulias, V.1
Plataniotis, G.2
Kouvaris, J.3
Dardoufas, C.4
Gennatas, C.5
Uzunoglu, N.6
Papavasiliou, C.7
Vlahos, L.8
-
24
-
-
0037462660
-
Lsm proteins are required for normal processing and stability of ribosomal RNAs
-
Kufel, J., Allmang, E., Beggs, J., and Tollervey, D. 2003. Lsm proteins are required for normal processing and stability of ribosomal RNAs. J. Biol. Chem. 278: 2147-2156.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 2147-2156
-
-
Kufel, J.1
Allmang, E.2
Beggs, J.3
Tollervey, D.4
-
25
-
-
0038387494
-
5-fluorouracil: Mechanism of action and clinical strategies
-
Longley, D.B., Harkin, D.P., and Johnston, P.G. 2003. 5-fluorouracil: Mechanism of action and clinical strategies. Nat. Rev. Cancer 3: 330-338.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 330-338
-
-
Longley, D.B.1
Harkin, D.P.2
Johnston, P.G.3
-
26
-
-
27144474752
-
The Kluyveromyces lactis γ-toxin targets tRNA anticodons
-
Lu, J., Huang, B., Esberg, A., Johanson, M.J., and Byström, A.S. 2005. The Kluyveromyces lactis γ-toxin targets tRNA anticodons. RNA 11: 1648-1654.
-
(2005)
RNA
, vol.11
, pp. 1648-1654
-
-
Lu, J.1
Huang, B.2
Esberg, A.3
Johanson, M.J.4
Byström, A.S.5
-
27
-
-
10744225364
-
Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes
-
Lum, P.Y., Armour, C.D., Stepaniants, S.B., Cavet, G., Wolf, M.K., Butler, J.S., Hinshaw, J.C., Garnier, P., Prestwich, G.D., Leonardson, A., et al. 2004. Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes. Cell 116: 121-137.
-
(2004)
Cell
, vol.116
, pp. 121-137
-
-
Lum, P.Y.1
Armour, C.D.2
Stepaniants, S.B.3
Cavet, G.4
Wolf, M.K.5
Butler, J.S.6
Hinshaw, J.C.7
Garnier, P.8
Prestwich, G.D.9
Leonardson, A.10
-
28
-
-
0033046012
-
Pseudouridine mapping in the Saccharomyces cerevisiae spliceosomal U small nuclear RNAs (snRNAs) reveals that pseudouridine synthase Pus1p exhibits a dual substrate specificity for U2 snRNA and tRNA
-
Massenet, S., Motorin, Y., Lafontaine, D.L.J., Hurt, E.C., Grosjean, H., and Branlant, C. 1999. Pseudouridine mapping in the Saccharomyces cerevisiae spliceosomal U small nuclear RNAs (snRNAs) reveals that pseudouridine synthase Pus1p exhibits a dual substrate specificity for U2 snRNA and tRNA. Mol. Cell. Biol. 19: 2142-2154.
-
(1999)
Mol. Cell. Biol
, vol.19
, pp. 2142-2154
-
-
Massenet, S.1
Motorin, Y.2
Lafontaine, D.L.J.3
Hurt, E.C.4
Grosjean, H.5
Branlant, C.6
-
29
-
-
0031870753
-
The yeast tRNA:pseudouridine synthase Pus1p displays a multisite substrate specificity
-
Motorin, Y., Keith, G., Simon, C., Foiret, D., Simos, G., Hurt, E., and Grosjean, H. 1998. The yeast tRNA:pseudouridine synthase Pus1p displays a multisite substrate specificity. RNA 4: 856-869.
-
(1998)
RNA
, vol.4
, pp. 856-869
-
-
Motorin, Y.1
Keith, G.2
Simon, C.3
Foiret, D.4
Simos, G.5
Hurt, E.6
Grosjean, H.7
-
30
-
-
0035970011
-
Identification of yeast deletion strains that are hypersensitive to brefeldin A or monensin, two drugs that affect intracellular transport
-
Murén, E., Oyen, M., Barmark, G., and Ronne, H. 2001. Identification of yeast deletion strains that are hypersensitive to brefeldin A or monensin, two drugs that affect intracellular transport. Yeast 18: 163-172.
-
(2001)
Yeast
, vol.18
, pp. 163-172
-
-
Murén, E.1
Oyen, M.2
Barmark, G.3
Ronne, H.4
-
32
-
-
0032971711
-
Elongator, a multisubunit component of a novel RNA polymerase II holoenzyme for transcriptional elongation
-
Otero, G., Fellows, J., Li, Y., de Bizemont, T., Dirac, A.M., Gustafsson, C.M., Erdjument-Bromage, H., Tempst, P., and Svejstrup, J.Q. 1999. Elongator, a multisubunit component of a novel RNA polymerase II holoenzyme for transcriptional elongation. Mol. Cell 3: 109-118.
-
(1999)
Mol. Cell
, vol.3
, pp. 109-118
-
-
Otero, G.1
Fellows, J.2
Li, Y.3
de Bizemont, T.4
Dirac, A.M.5
Gustafsson, C.M.6
Erdjument-Bromage, H.7
Tempst, P.8
Svejstrup, J.Q.9
-
33
-
-
0025611018
-
Metabolism and mechanism of action of 5-fluorouracil
-
Parker, W.B. and Cheng, Y.C. 1990. Metabolism and mechanism of action of 5-fluorouracil. Pharmacol. Ther. 48: 381-395.
-
(1990)
Pharmacol. Ther
, vol.48
, pp. 381-395
-
-
Parker, W.B.1
Cheng, Y.C.2
-
34
-
-
0032500682
-
TOM1p, a yeast hect-domain protein which mediates transcriptional regulation through the ADA/SAGA coactivator complexes
-
Saleh, A., Collart, M., Martens, J.A., Genereaux, J., Allard, S., Cote, J., and Brandl, C.J. 1998. TOM1p, a yeast hect-domain protein which mediates transcriptional regulation through the ADA/SAGA coactivator complexes. J. Mol. Biol. 282: 933-946.
-
(1998)
J. Mol. Biol
, vol.282
, pp. 933-946
-
-
Saleh, A.1
Collart, M.2
Martens, J.A.3
Genereaux, J.4
Allard, S.5
Cote, J.6
Brandl, C.J.7
-
35
-
-
0026008878
-
Interaction of transfer RNA pseudouridine synthases with RNAs substituted with fluorouracil
-
doi: 10.1093/nar/19.22.6139
-
Samuelsson, T. 1991. Interaction of transfer RNA pseudouridine synthases with RNAs substituted with fluorouracil. Nucleic Acids Res. 19: 6139-6144. doi: 10.1093/nar/19.22.6139.
-
(1991)
Nucleic Acids Res
, vol.19
, pp. 6139-6144
-
-
Samuelsson, T.1
-
36
-
-
0023667711
-
Catalytic mechanism and inhibition of tRNA (uracil-5-)methyltransferase: Evidence for covalent catalysis
-
Santi, D.V. and Hardy, L.W. 1987. Catalytic mechanism and inhibition of tRNA (uracil-5-)methyltransferase: Evidence for covalent catalysis. Biochemistry 26: 8599-8606.
-
(1987)
Biochemistry
, vol.26
, pp. 8599-8606
-
-
Santi, D.V.1
Hardy, L.W.2
-
37
-
-
0003529274
-
-
Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
-
Sherman, F., Fink, G., and Hicks, J.B 1986. Methods in yeast genetics. A laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
-
(1986)
Methods in yeast genetics. A laboratory manual
-
-
Sherman, F.1
Fink, G.2
Hicks, J.B.3
-
38
-
-
0035106451
-
Genes encoding ribosomal proteins Rps0A/B of Saccharomyces cerevisiae interact with TOM1 mutants defective in ribosome synthesis
-
Tabb, A.L., Utsugi, T., Wooten-Kee, C.R., Sasaki, T., Edling, S.A., Gump, W., Kikuchi, Y., and Ellis, S.R. 2001. Genes encoding ribosomal proteins Rps0A/B of Saccharomyces cerevisiae interact with TOM1 mutants defective in ribosome synthesis. Genetics 157: 1107-1116.
-
(2001)
Genetics
, vol.157
, pp. 1107-1116
-
-
Tabb, A.L.1
Utsugi, T.2
Wooten-Kee, C.R.3
Sasaki, T.4
Edling, S.A.5
Gump, W.6
Kikuchi, Y.7
Ellis, S.R.8
-
39
-
-
2342421220
-
The specificities of four yeast dihydrouridine synthase for cytoplasmic tRNAs
-
Xing, F., Hiley, S.L., Hughes, T.R., and Phizicky, E.M. 2004. The specificities of four yeast dihydrouridine synthase for cytoplasmic tRNAs. J. Biol. Chem. 279: 17850-17860.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 17850-17860
-
-
Xing, F.1
Hiley, S.L.2
Hughes, T.R.3
Phizicky, E.M.4
-
40
-
-
33846923097
-
Incorporation of 5-fluorouracil into U2 snRNA blocks pseudouridylation and pre-mRNA splicing in vivo
-
doi: 10.1093/nar/gkl1084
-
Zhao, X. and Yu, Y.-T. 2007. Incorporation of 5-fluorouracil into U2 snRNA blocks pseudouridylation and pre-mRNA splicing in vivo. Nucleic Acids Res. 35: 550-558. doi: 10.1093/nar/gkl1084.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 550-558
-
-
Zhao, X.1
Yu, Y.-T.2
|