N-Aroyl-3,5-bis(benzylidene)-4-piperidones: A novel class of antimycobacterial agents

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 7, 2008, Pages 3602-3607

  Das, Umashankar ^a   Das, Swagatika ^a   Bandy, Brian ^a   Stables, James P ^b   Dimmock, Jonathan R ^a  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

^b NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

Author keywords

3,5 Bis(benzylidene) 4 piperidones; Antimycobacterial; Antitubercular; Mitochondria; Neurotoxic; Piperidones; Rodent toxicity

Indexed keywords

3,5 BIS(BENZYLIDENE) 4 PIPERIDONE; ANTIMYCOBACTERIAL AGENT; BENZYLIDENE DERIVATIVE; N 4 (2 AMINOETHOXY)PHENYLCARBONY; N AROYL 3,5 BIS(BENZYLIDENE) 4 PIPERIDONE; RIFAMPICIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIMICROBIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DISEASE MODEL; DRUG SYNTHESIS; DRUG TOLERABILITY; IN VITRO STUDY; LIVER; MITOCHONDRION; MOUSE; NEUROTOXICITY; NONHUMAN; RAT; RODENT;

ANIMALS; ANTI-BACTERIAL AGENTS; MICE; MOLECULAR STRUCTURE; MYCOBACTERIUM TUBERCULOSIS; PIPERIDONES; RATS; STRUCTURE-ACTIVITY RELATIONSHIP;

MUS; RATTUS; RODENTIA;

EID: 41649096500     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.02.009     Document Type: Article

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