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Volumn 149, Issue 4, 2008, Pages 1551-1561

Gene expression analyses in cynomolgus monkeys provides mechanistic insight into high-density lipoprotein-cholesterol reduction by androgens in primates

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; ANDROSTANOLONE; APOLIPOPROTEIN C1; CHOLESTEROL 7ALPHA MONOOXYGENASE; DRUG VEHICLE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

EID: 41549111592     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2007-1151     Document Type: Article
Times cited : (12)

References (58)
  • 1
    • 33646679639 scopus 로고    scopus 로고
    • Testosterone therapy for postmenopausal women: Efficacy and safety
    • Somboonporn W 2006 Testosterone therapy for postmenopausal women: efficacy and safety. Semin Reprod Med 24:115-124
    • (2006) Semin Reprod Med , vol.24 , pp. 115-124
    • Somboonporn, W.1
  • 2
    • 29544444474 scopus 로고    scopus 로고
    • Cardiovascular issues in hypogonadism and testosterone therapy
    • Shabsigh R, Katz M, Yan G, Makhsida N 2005 Cardiovascular issues in hypogonadism and testosterone therapy. Am J Cardiol 96:67M-72M
    • (2005) Am J Cardiol , vol.96
    • Shabsigh, R.1    Katz, M.2    Yan, G.3    Makhsida, N.4
  • 3
    • 0037396460 scopus 로고    scopus 로고
    • Androgens and coronary artery disease
    • Wu FC, von Eckardstein A 2003 Androgens and coronary artery disease. Endocr Rev 24:183-217
    • (2003) Endocr Rev , vol.24 , pp. 183-217
    • Wu, F.C.1    von Eckardstein, A.2
  • 4
    • 33748458429 scopus 로고    scopus 로고
    • Relative androgen deficiency in relation to obesity and metabolic status in older men
    • Chen RY, Wittert GA, Andrews GR 2006 Relative androgen deficiency in relation to obesity and metabolic status in older men. Diabetes Obes Metab 8:429-435
    • (2006) Diabetes Obes Metab , vol.8 , pp. 429-435
    • Chen, R.Y.1    Wittert, G.A.2    Andrews, G.R.3
  • 6
  • 7
    • 0036743775 scopus 로고    scopus 로고
    • Effect of surgical castration on risk factors for arteriosclerosis of patients with prostate cancer
    • Xu T, Wang X, Hou S, Zhu J, Zhang X, Huang X 2002 Effect of surgical castration on risk factors for arteriosclerosis of patients with prostate cancer. Chin Med J (Engl) 115:1336-1340
    • (2002) Chin Med J (Engl) , vol.115 , pp. 1336-1340
    • Xu, T.1    Wang, X.2    Hou, S.3    Zhu, J.4    Zhang, X.5    Huang, X.6
  • 9
    • 0037280752 scopus 로고    scopus 로고
    • The CAG repeat polymorphism in the androgen receptor gene modulates body fat mass and serum concentrations of leptin and insulin in men
    • Zitzmann M, Gromoll J, von Eckardstein A, Nieschlag E 2003 The CAG repeat polymorphism in the androgen receptor gene modulates body fat mass and serum concentrations of leptin and insulin in men. Diabetologia 46:31-39
    • (2003) Diabetologia , vol.46 , pp. 31-39
    • Zitzmann, M.1    Gromoll, J.2    von Eckardstein, A.3    Nieschlag, E.4
  • 10
    • 23444459874 scopus 로고    scopus 로고
    • The CAG repeat polymorphism in the androgen receptor gene is associated with HDL-cholesterol but not with coronary atherosclerosis or myocardial infarction
    • Hersberger M, Muntwyler J, Funke H, Marti-Jaun J, Schulte H, Assmann G, Luscher TF, von Eckardstein A 2005 The CAG repeat polymorphism in the androgen receptor gene is associated with HDL-cholesterol but not with coronary atherosclerosis or myocardial infarction. Clin Chem 51:1110-1115
    • (2005) Clin Chem , vol.51 , pp. 1110-1115
    • Hersberger, M.1    Muntwyler, J.2    Funke, H.3    Marti-Jaun, J.4    Schulte, H.5    Assmann, G.6    Luscher, T.F.7    von Eckardstein, A.8
  • 11
    • 33747353010 scopus 로고    scopus 로고
    • The androgen receptor gene CAG repeat polymorphism does not predict increased risk of heart disease: Longitudinal results from the Massachusetts Male Ageing Study
    • Page ST, Kupelian V, Bremner WJ, McKinlay JB 2006 The androgen receptor gene CAG repeat polymorphism does not predict increased risk of heart disease: longitudinal results from the Massachusetts Male Ageing Study. Clin Endocrinol (Oxf) 65:333-339
    • (2006) Clin Endocrinol (Oxf) , vol.65 , pp. 333-339
    • Page, S.T.1    Kupelian, V.2    Bremner, W.J.3    McKinlay, J.B.4
  • 12
    • 34249285167 scopus 로고    scopus 로고
    • Why men's hearts break: Cardiovascular effects of sex steroids
    • Choi BG, McLaughlin MA 2007 Why men's hearts break: cardiovascular effects of sex steroids. Endocrinol Metab Clin North Am 36:365-377
    • (2007) Endocrinol Metab Clin North Am , vol.36 , pp. 365-377
    • Choi, B.G.1    McLaughlin, M.A.2
  • 13
    • 23844497854 scopus 로고    scopus 로고
    • Effects of androgens on the cardiovascular system
    • Rosano GM, Cornoldi A, Fini M 2005 Effects of androgens on the cardiovascular system. J Endocrinol Invest 28:32-38
    • (2005) J Endocrinol Invest , vol.28 , pp. 32-38
    • Rosano, G.M.1    Cornoldi, A.2    Fini, M.3
  • 14
    • 0033574718 scopus 로고    scopus 로고
    • Natural androgens inhibit male atherosclerosis: A study in castrated, cholesterol-fed rabbits
    • Alexandersen P, Haarbo J, Byrjalsen I, Lawaetz H, Christiansen C 1999 Natural androgens inhibit male atherosclerosis: a study in castrated, cholesterol-fed rabbits. Circ Res 84:813-819
    • (1999) Circ Res , vol.84 , pp. 813-819
    • Alexandersen, P.1    Haarbo, J.2    Byrjalsen, I.3    Lawaetz, H.4    Christiansen, C.5
  • 16
    • 0141507941 scopus 로고    scopus 로고
    • Testosterone as a protective factor against atherosclerosis - immunomodulation and influence upon plaque development and stability
    • Malkin CJ, Pugh PJ, Jones RD, Jones TH, Channer KS 2003 Testosterone as a protective factor against atherosclerosis - immunomodulation and influence upon plaque development and stability. J Endocrinol 178:373-380
    • (2003) J Endocrinol , vol.178 , pp. 373-380
    • Malkin, C.J.1    Pugh, P.J.2    Jones, R.D.3    Jones, T.H.4    Channer, K.S.5
  • 17
    • 0032958840 scopus 로고    scopus 로고
    • Hepatic lipase activity influences high density lipoprotein subclass distribution in normotriglyceridemic men. Genetic and pharmacological evidence
    • Grundy SM, Vega GL, Otvos JD, Rainwater DL, Cohen JC 1999 Hepatic lipase activity influences high density lipoprotein subclass distribution in normotriglyceridemic men. Genetic and pharmacological evidence. J Lipid Res 40:229-234
    • (1999) J Lipid Res , vol.40 , pp. 229-234
    • Grundy, S.M.1    Vega, G.L.2    Otvos, J.D.3    Rainwater, D.L.4    Cohen, J.C.5
  • 18
    • 0036197111 scopus 로고    scopus 로고
    • Impact on lipoprotein profile after long-term testosterone replacement in hypogonadal men
    • Berg G, Schreier L, Geloso G, Otero P, Nagelberg A, Levalle O 2002 Impact on lipoprotein profile after long-term testosterone replacement in hypogonadal men. Horm Metab Res 34:87-92
    • (2002) Horm Metab Res , vol.34 , pp. 87-92
    • Berg, G.1    Schreier, L.2    Geloso, G.3    Otero, P.4    Nagelberg, A.5    Levalle, O.6
  • 19
    • 0030819481 scopus 로고    scopus 로고
    • Effects of short-term stanozolol administration on serum lipoproteins in hepatic lipase deficiency
    • Bausserman LL, Saritelli AL, Herbert PN 1997 Effects of short-term stanozolol administration on serum lipoproteins in hepatic lipase deficiency. Metabolism 46:992-996
    • (1997) Metabolism , vol.46 , pp. 992-996
    • Bausserman, L.L.1    Saritelli, A.L.2    Herbert, P.N.3
  • 20
    • 0031415969 scopus 로고    scopus 로고
    • Testosterone, sex hormone-binding globulin, lipoproteins, and vascular disease risk
    • Dickerman RD, McConathy WJ, Zachariah NY 1997 Testosterone, sex hormone-binding globulin, lipoproteins, and vascular disease risk. J Cardiovasc Risk 4:363-366
    • (1997) J Cardiovasc Risk , vol.4 , pp. 363-366
    • Dickerman, R.D.1    McConathy, W.J.2    Zachariah, N.Y.3
  • 21
    • 0033927588 scopus 로고    scopus 로고
    • The adipose tissue metabolism: Role of testosterone and dehydroepiandrosterone
    • De Pergola G 2000 The adipose tissue metabolism: role of testosterone and dehydroepiandrosterone. Int J Obes Relat Metab Disord 24(Suppl 2):S59-S63
    • (2000) Int J Obes Relat Metab Disord , vol.24 , Issue.SUPPL. 2
    • De Pergola, G.1
  • 22
    • 0024618726 scopus 로고
    • Atherosclerosis research in cynomolgus monkeys (Macaca fascicularis)
    • Weingand KW 1989 Atherosclerosis research in cynomolgus monkeys (Macaca fascicularis). Exp Mol Pathol 50:1-15
    • (1989) Exp Mol Pathol , vol.50 , pp. 1-15
    • Weingand, K.W.1
  • 23
    • 0021676532 scopus 로고
    • Psychosocial and reproductive influences on plasma lipids, lipoproteins, and atherosclerosis in nonhuman primates
    • Clarkson TB, Adams MR, Kaplan JR, Koritnik DR 1984 Psychosocial and reproductive influences on plasma lipids, lipoproteins, and atherosclerosis in nonhuman primates. J Lipid Res 25:1629-1634
    • (1984) J Lipid Res , vol.25 , pp. 1629-1634
    • Clarkson, T.B.1    Adams, M.R.2    Kaplan, J.R.3    Koritnik, D.R.4
  • 25
    • 0033379825 scopus 로고    scopus 로고
    • Alterations in hepatic lipase and lipoprotein subfractions with transdermal testosterone replacement therapy
    • Tan KC, Shiu SW, Kung AW 1999 Alterations in hepatic lipase and lipoprotein subfractions with transdermal testosterone replacement therapy. Clin Endocrinol (Oxf) 51:765-769
    • (1999) Clin Endocrinol (Oxf) , vol.51 , pp. 765-769
    • Tan, K.C.1    Shiu, S.W.2    Kung, A.W.3
  • 27
    • 0029890650 scopus 로고    scopus 로고
    • Regulation of somatic growth and the somatotropic axis by gonadal steroids: Primary effect on insulin-like growth factor I gene expression and secretion
    • Borski RJ, Tsai W, DeMott-Friberg R, Barkan AL 1996 Regulation of somatic growth and the somatotropic axis by gonadal steroids: primary effect on insulin-like growth factor I gene expression and secretion. Endocrinology 137:3253-3259
    • (1996) Endocrinology , vol.137 , pp. 3253-3259
    • Borski, R.J.1    Tsai, W.2    DeMott-Friberg, R.3    Barkan, A.L.4
  • 28
    • 27844509037 scopus 로고    scopus 로고
    • Transcriptional corepression by SHP: Molecular mechanisms and physiological consequences
    • Bavner A, Sanyal S, Gustafsson JA, Treuter E 2005 Transcriptional corepression by SHP: molecular mechanisms and physiological consequences. Trends Endocrinol Metab 16:478-488
    • (2005) Trends Endocrinol Metab , vol.16 , pp. 478-488
    • Bavner, A.1    Sanyal, S.2    Gustafsson, J.A.3    Treuter, E.4
  • 29
  • 30
    • 0031798630 scopus 로고    scopus 로고
    • Androgen receptors in human preadipocytes and adipocytes: Regional specificities and regulation by sex steroids
    • Dieudonne MN, Pecquery R, Boumediene A, Leneveu MC, Giudicelli Y 1998 Androgen receptors in human preadipocytes and adipocytes: regional specificities and regulation by sex steroids. Am J Physiol 274:C1645-C1652
    • (1998) Am J Physiol , vol.274
    • Dieudonne, M.N.1    Pecquery, R.2    Boumediene, A.3    Leneveu, M.C.4    Giudicelli, Y.5
  • 31
    • 34347236550 scopus 로고    scopus 로고
    • Effects of testosterone and estrogen treatment on lipolysis signaling pathways in subcutaneous adipose tissue of postmenopausal women
    • Zang H, Ryden M, Wahlen K, Dahlman-Wright K, Arner P, Linden Hirschberg A 2007 Effects of testosterone and estrogen treatment on lipolysis signaling pathways in subcutaneous adipose tissue of postmenopausal women. Fertil Steril 88:100-106
    • (2007) Fertil Steril , vol.88 , pp. 100-106
    • Zang, H.1    Ryden, M.2    Wahlen, K.3    Dahlman-Wright, K.4    Arner, P.5    Linden Hirschberg, A.6
  • 32
    • 0036259046 scopus 로고    scopus 로고
    • The regulation of HSL and LPL expression by DHT and flutamide in human subcutaneous adipose tissue
    • Anderson LA, McTernan PG, Harte AL, Barnett AH, Kumar S 2002 The regulation of HSL and LPL expression by DHT and flutamide in human subcutaneous adipose tissue. Diabetes Obes Metab 4:209-213
    • (2002) Diabetes Obes Metab , vol.4 , pp. 209-213
    • Anderson, L.A.1    McTernan, P.G.2    Harte, A.L.3    Barnett, A.H.4    Kumar, S.5
  • 33
    • 29244491445 scopus 로고    scopus 로고
    • Insulin-like growth factor I, growth hormone and insulin in white adipose tissue
    • Bluher S, Kratzsch J, Kiess W 2005 Insulin-like growth factor I, growth hormone and insulin in white adipose tissue. Best Pract Res Clin Endocrinol Metab 19:577-587
    • (2005) Best Pract Res Clin Endocrinol Metab , vol.19 , pp. 577-587
    • Bluher, S.1    Kratzsch, J.2    Kiess, W.3
  • 37
    • 0141631436 scopus 로고    scopus 로고
    • Testosterone and atherosclerosis
    • Eckardstein A, Wu FC 2003 Testosterone and atherosclerosis. Growth Horm IGF Res 13(Suppl A):S72-S84
    • (2003) Growth Horm IGF Res , vol.13 , Issue.SUPPL. A
    • Eckardstein, A.1    Wu, F.C.2
  • 38
    • 33645108179 scopus 로고    scopus 로고
    • Oxandrolone in the treatment of HIV-associated weight loss in men: A randomized, double-blind, placebo-controlled study
    • Grunfeld C, Kotler DP, Dobs A, Glesby M, Bhasin S 2006 Oxandrolone in the treatment of HIV-associated weight loss in men: a randomized, double-blind, placebo-controlled study. J Acquir Immune Defic Syndr 41:304-314
    • (2006) J Acquir Immune Defic Syndr , vol.41 , pp. 304-314
    • Grunfeld, C.1    Kotler, D.P.2    Dobs, A.3    Glesby, M.4    Bhasin, S.5
  • 41
    • 0037340125 scopus 로고    scopus 로고
    • Differential regulation of rat and human CYP7A1 by the nuclear oxysterol receptor liver X receptor-α
    • Goodwin B, Watson MA, Kim H, Miao J, Kemper JK, Kliewer SA 2003 Differential regulation of rat and human CYP7A1 by the nuclear oxysterol receptor liver X receptor-α. Mol Endocrinol 17:386-394
    • (2003) Mol Endocrinol , vol.17 , pp. 386-394
    • Goodwin, B.1    Watson, M.A.2    Kim, H.3    Miao, J.4    Kemper, J.K.5    Kliewer, S.A.6
  • 43
    • 33747597081 scopus 로고    scopus 로고
    • The nuclear hormone receptor farnesoid X receptor (FXR) is activated by androsterone
    • Wang S, Lai K, Moy FJ, Bhat A, Hartman HB, Evans MJ 2006 The nuclear hormone receptor farnesoid X receptor (FXR) is activated by androsterone. Endocrinology 147:4025-4033
    • (2006) Endocrinology , vol.147 , pp. 4025-4033
    • Wang, S.1    Lai, K.2    Moy, F.J.3    Bhat, A.4    Hartman, H.B.5    Evans, M.J.6
  • 46
    • 29344440814 scopus 로고    scopus 로고
    • Testosterone inhibits adipogenic differentiation in 3T3-L1 cells: Nuclear translocation of androgen receptor complex with β-catenin and T-cell factor 4 may bypass canonical Wnt signaling to down-regulate adipogenic transcription factors
    • Singh R, Artaza JN, Taylor WE, Braga M, Yuan X, Gonzalez-Cadavid NF, Bhasin S 2006 Testosterone inhibits adipogenic differentiation in 3T3-L1 cells: nuclear translocation of androgen receptor complex with β-catenin and T-cell factor 4 may bypass canonical Wnt signaling to down-regulate adipogenic transcription factors. Endocrinology 147:141-154
    • (2006) Endocrinology , vol.147 , pp. 141-154
    • Singh, R.1    Artaza, J.N.2    Taylor, W.E.3    Braga, M.4    Yuan, X.5    Gonzalez-Cadavid, N.F.6    Bhasin, S.7
  • 47
    • 0242468434 scopus 로고    scopus 로고
    • Androgens stimulate myogenic differentiation and inhibit adipogenesis in C3H 10T1/2 pluripotent cells through an androgen receptor-mediated pathway
    • Singh R, Artaza JN, Taylor WE, Gonzalez-Cadavid NF, Bhasin S 2003 Androgens stimulate myogenic differentiation and inhibit adipogenesis in C3H 10T1/2 pluripotent cells through an androgen receptor-mediated pathway. Endocrinology 144:5081-5088
    • (2003) Endocrinology , vol.144 , pp. 5081-5088
    • Singh, R.1    Artaza, J.N.2    Taylor, W.E.3    Gonzalez-Cadavid, N.F.4    Bhasin, S.5
  • 48
    • 16244382558 scopus 로고    scopus 로고
    • Androgen receptor null male mice develop late-onset obesity caused by decreased energy expenditure and lipolytic activity but show normal insulin sensitivity with high adiponectin secretion
    • Fan W, Yanase T, Nomura M, Okabe T, Goto K, Sato T, Kawano H, Kato S, Nawata H 2005 Androgen receptor null male mice develop late-onset obesity caused by decreased energy expenditure and lipolytic activity but show normal insulin sensitivity with high adiponectin secretion. Diabetes 54:1000-1008
    • (2005) Diabetes , vol.54 , pp. 1000-1008
    • Fan, W.1    Yanase, T.2    Nomura, M.3    Okabe, T.4    Goto, K.5    Sato, T.6    Kawano, H.7    Kato, S.8    Nawata, H.9
  • 49
    • 21244481801 scopus 로고    scopus 로고
    • Wnt signaling inhibits adipogenesis through β-catenin-dependent and -independent mechanisms
    • Kennell JA, MacDougald OA 2005 Wnt signaling inhibits adipogenesis through β-catenin-dependent and -independent mechanisms. J Biol Chem 280:24004-24010
    • (2005) J Biol Chem , vol.280 , pp. 24004-24010
    • Kennell, J.A.1    MacDougald, O.A.2
  • 51
    • 0025761710 scopus 로고
    • Plasma lipid transfer protein as a determinant of the atherogenicity of monkey plasma lipoproteins
    • Quinet E, Tall A, Ramakrishnan R, Rudel L 1991 Plasma lipid transfer protein as a determinant of the atherogenicity of monkey plasma lipoproteins. J Clin Invest 87:1559-1566
    • (1991) J Clin Invest , vol.87 , pp. 1559-1566
    • Quinet, E.1    Tall, A.2    Ramakrishnan, R.3    Rudel, L.4
  • 55
    • 34247882089 scopus 로고    scopus 로고
    • Obesity and atherogenic dyslipidemia
    • Bamba V, Rader DJ 2007 Obesity and atherogenic dyslipidemia. Gastroenterology 132:2181-2190
    • (2007) Gastroenterology , vol.132 , pp. 2181-2190
    • Bamba, V.1    Rader, D.J.2
  • 56
    • 0023155197 scopus 로고
    • Regional variation in high-density lipoprotein binding to human adipocyte plasma membranes of massively obese subjects
    • Salter AM, Fong BS, Jimenez J, Rotstein L, Angel A 1987 Regional variation in high-density lipoprotein binding to human adipocyte plasma membranes of massively obese subjects. Eur J Clin Invest 17:16-22
    • (1987) Eur J Clin Invest , vol.17 , pp. 16-22
    • Salter, A.M.1    Fong, B.S.2    Jimenez, J.3    Rotstein, L.4    Angel, A.5
  • 57
    • 33646826006 scopus 로고    scopus 로고
    • Lipid and lipoprotein dysregulation in insulin resistant states
    • Avramoglu RK, Basciano H, Adeli K 2006 Lipid and lipoprotein dysregulation in insulin resistant states. Clin Chim Acta 368:1-19
    • (2006) Clin Chim Acta , vol.368 , pp. 1-19
    • Avramoglu, R.K.1    Basciano, H.2    Adeli, K.3
  • 58
    • 19944366619 scopus 로고    scopus 로고
    • Regulation of plasma triglycerides in insulin resistance and diabetes
    • Ginsberg HN, Zhang YL, Hernandez-Ono A 2005 Regulation of plasma triglycerides in insulin resistance and diabetes. Arch Med Res 36:232-240
    • (2005) Arch Med Res , vol.36 , pp. 232-240
    • Ginsberg, H.N.1    Zhang, Y.L.2    Hernandez-Ono, A.3


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