Crystal Structure of the CaV2 IQ Domain in Complex with Ca2+/Calmodulin: High-Resolution Mechanistic Implications for Channel Regulation by Ca2+

Structure

Volumn 16, Issue 4, 2008, Pages 607-620

  Mori, Masayuki X ^a   Vander Kooi, Craig W ^b   Leahy, Daniel J ^b   Yue, David T ^a  

^a Department of Biomedical Engineering   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

PROTEINS

Indexed keywords

CALCIUM ION; CALMODULIN; MUTANT PROTEIN; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL; VOLTAGE GATED CALCIUM CHANNEL 2.1; VOLTAGE GATED CALCIUM CHANNEL 2.3; ALANINE; CALCIUM; CALCIUM CHANNEL N TYPE; CALCIUM CHANNEL R TYPE; VOLTAGE DEPENDENT CALCIUM CHANNEL (P Q TYPE); VOLTAGE-DEPENDENT CALCIUM CHANNEL (P-Q TYPE);

ARTICLE; CRYSTAL STRUCTURE; EMBRYO; ENERGY; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; MUTATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN STRUCTURE; REGULATORY MECHANISM; SIMULATION; STRUCTURE ANALYSIS; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; MOLECULAR GENETICS; MUTAGENESIS; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY; X RAY CRYSTALLOGRAPHY;

ALANINE; AMINO ACID SEQUENCE; CALCIUM; CALCIUM CHANNELS, N-TYPE; CALCIUM CHANNELS, R-TYPE; CALMODULIN; CRYSTALLOGRAPHY, X-RAY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 41449096289     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.str.2008.01.011     Document Type: Article

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