Functional Stoichiometry and Local Enrichment of Calmodulin Interacting with Ca2+ Channels

Science

Volumn 304, Issue 5669, 2004, Pages 432-435

  Mori, Masayuki X ^a   Erickson, Michael G ^a   Yue, David T ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MOLECULAR STRUCTURE; NEUROLOGY; SIGNALING; STOICHIOMETRY;

CHIMERIC MOLECULES; FUSION MOLECULES; NEURONAL MEMORY;

PROTEINS;

CALCIUM CHANNEL; CALCIUM CHANNEL L TYPE; CALCIUM ION; CALMODULIN; TRANSCRIPTION FACTOR;

BIOLOGY;

ARTICLE; CALCIUM SIGNALING; CHIMERA; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STOICHIOMETRY;

CALCIUM; CALCIUM CHANNELS, L-TYPE; CALCIUM SIGNALING; CALMODULIN; CELL LINE; CELL NUCLEUS; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMANS; MATHEMATICS; MUTATION; PATCH-CLAMP TECHNIQUES; PEPTIDES; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; TRANSFECTION;

EID: 1942488175     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1093490     Document Type: Article

References (31)

1. B. Z. Peterson, C. D. DeMaria, J. P. Adelman, D. T. Yue, Neuron 22, 549 (1999).
2. R. D. Zuhlke, G. S. Pitt, K. Deisseroth, R. W. Tsien, H. Reuter, Nature 399, 159 (1999).
3. N. Qin, R. Olcese, M. Bransby, T. Lin, L. Birnbaumer, Proc. Natl. Acad. Sci. U.S.A. 96, 2435 (1999).
4. A. Lee et al., Nature 399, 155 (1999).
5. H. Liang et al., Neuron 39, 951 (2003).
6. S. C. Stotz, S. E. Jarvis, G. W. Zamponi, J. Physiol. (London) 554, 263 (2004); published online 18 June 2003.
7. K. Deisserath, H. Bito, R. W. Tsien, Neuron 16, 89 (1996).
8. K. G. Sutton, J. E. McRory, H. Guthrie, T. H. Murphy, T. P. Snutch, Nature 401, 800 (1999).
9. R. E. Dolmetsch, U. Pajvani, K. Fife, J. M. Spotts, M. E. Greenberg, Science 294, 333 (2001).
10. I. A. Graef et al., Nature 401, 703 (1999).
11. M. G. Erickson, B. A. Alseikhan, B. Z. Peterson, D. T. Yue, Neuron 31, 973 (2001).
12. M. G. Erickson, H. Liang, M. X. Mori, D. T. Yue, Neuron 39, 97 (2003).
13. C. D. DeMaria, T. W. Soong, B. A. Alseikhan, R. S. Alvania, D. T. Yue, Nature 411, 484 (2001).
14. T. W. Soong et al., Neurosci. 22, 10142 (2002).
15. K. Deisseroth, E. K. Heist, R. W. Tsien, Nature 392, 198 (1998).
16. P. K. Dash, B. Hochner, E. R. Kandel, Nature 345, 718 (1990).
17. S. H. Cheng, M. R. Willmann, H. C. Chen, J. Sheen, Plant Physiol. 129, 469 (2002).
18. S. R. Ikeda, Science 294, 318 (2001).
19. W. Tang et al., Biophys. J. 85, 1538 (2003).
20. T. Ivanina, Y. Blumenstein, E. Shistik, R. Barzilai, N. Dascal, J. Biol. Chem. 275, 39846 (2000).
21. G. S. Pitt et al., J. Biol. Chem. 276, 30794 (2001).
22. T. H. Murphy, P. F. Worley, J. M. Baraban, Neuron 7, 625 (1991).
23. B. A. Alseikhan, C. D. DeMaria, H. M. Colecraft, D. T. Yue, Proc. Natl. Acad. Sci. U.S.A. 99, 17185 (2002).
24. C. R. Cantor, P. R. Schimmel, Biophysical Chemistry. Part III: The Behavior of Biological Macromolecules (Freeman, San Francisco, 1980).
25. A. Persechini, P. M. Stemmer, Trends Cardiovasc. Med. 12, 32 (2002).
26. L. S. Maier, D. M. Bers, B. Pieske, J. Mol. Cell. Cardiol. 32, 2249 (2000).
27. A. Persechini, B. Cronk, J. Biol. Chem. 274, 6827 (1999).
28. M. A. Schumacher, A. F. Rivard, H. P. Bachinger, J. P. Adelman, Nature 410, 1120 (2001).
29. M. C. Wang et al., J. Mol. Biol. 323, 85 (2002).
30. M. J. Root, R. MacKinnon, Science 265, 1852 (1994).
31. 2+ Signals Laboratory for comments and discussion. This work was supported by grants from the NIH (D.T.Y.).