메뉴 건너뛰기




Volumn 29, Issue 4, 2008, Pages 170-174

Free immunoglobulin light chains: a novel target in the therapy of inflammatory diseases

Author keywords

[No Author keywords available]

Indexed keywords

F 991; IMMUNOGLOBULIN E; IMMUNOGLOBULIN LIGHT CHAIN; PROTEIN INHIBITOR; UNCLASSIFIED DRUG;

EID: 41349097051     PISSN: 01656147     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tips.2008.01.004     Document Type: Article
Times cited : (53)

References (64)
  • 1
    • 0022486976 scopus 로고
    • Evidence by radioimmunoassay that mitogen-activated human blood mononuclear cells secrete significant amounts of light chain Ig unassociated with heavy chain
    • Hopper J.E., and Papagiannes E. Evidence by radioimmunoassay that mitogen-activated human blood mononuclear cells secrete significant amounts of light chain Ig unassociated with heavy chain. Cell. Immunol. 101 (1986) 122-131
    • (1986) Cell. Immunol. , vol.101 , pp. 122-131
    • Hopper, J.E.1    Papagiannes, E.2
  • 2
    • 0014431896 scopus 로고
    • Relative rates of synthesis of immunoglobulins and light chains in rabbit spleen cells during secondary response
    • Skvortsov V.T., and Gurvich A.E. Relative rates of synthesis of immunoglobulins and light chains in rabbit spleen cells during secondary response. Nature 218 (1968) 377-378
    • (1968) Nature , vol.218 , pp. 377-378
    • Skvortsov, V.T.1    Gurvich, A.E.2
  • 3
    • 0019504766 scopus 로고
    • Free immunoglobulin light chain synthesis by human foetal liver and cord blood lymphocytes
    • Hannam-Harris A.C., and Smith J.L. Free immunoglobulin light chain synthesis by human foetal liver and cord blood lymphocytes. Immunology 43 (1981) 417-423
    • (1981) Immunology , vol.43 , pp. 417-423
    • Hannam-Harris, A.C.1    Smith, J.L.2
  • 4
    • 0014019613 scopus 로고
    • Synthesis of excess light chains of gamma globulin by rabbit lymph node cells
    • Shapiro A.L., et al. Synthesis of excess light chains of gamma globulin by rabbit lymph node cells. Nature 211 (1966) 243-245
    • (1966) Nature , vol.211 , pp. 243-245
    • Shapiro, A.L.1
  • 5
    • 0035063345 scopus 로고    scopus 로고
    • Highly sensitive, automated immunoassay for immunoglobulin free light chains in serum and urine
    • Bradwell A.R., et al. Highly sensitive, automated immunoassay for immunoglobulin free light chains in serum and urine. Clin. Chem. 47 (2001) 673-680
    • (2001) Clin. Chem. , vol.47 , pp. 673-680
    • Bradwell, A.R.1
  • 6
    • 33644746124 scopus 로고    scopus 로고
    • Free immunoglobulin light chains as target in the treatment of chronic inflammatory diseases
    • van der Heijden M., et al. Free immunoglobulin light chains as target in the treatment of chronic inflammatory diseases. Eur. J. Pharmacol. 533 (2006) 319-326
    • (2006) Eur. J. Pharmacol. , vol.533 , pp. 319-326
    • van der Heijden, M.1
  • 8
    • 34247512849 scopus 로고    scopus 로고
    • The critical role of mast cells in allergy and inflammation
    • Theoharides T.C., and Kalogeromitros D. The critical role of mast cells in allergy and inflammation. Ann. N. Y. Acad. Sci. 1088 (2006) 78-99
    • (2006) Ann. N. Y. Acad. Sci. , vol.1088 , pp. 78-99
    • Theoharides, T.C.1    Kalogeromitros, D.2
  • 9
    • 0036065632 scopus 로고    scopus 로고
    • Immunoglobulin-free light chains elicit immediate hypersensitivity-like responses
    • Redegeld F.A., et al. Immunoglobulin-free light chains elicit immediate hypersensitivity-like responses. Nat. Med. 8 (2002) 694-701
    • (2002) Nat. Med. , vol.8 , pp. 694-701
    • Redegeld, F.A.1
  • 10
    • 13444255985 scopus 로고    scopus 로고
    • Elicitation of allergic asthma by immunoglobulin free light chains
    • Kraneveld A.D., et al. Elicitation of allergic asthma by immunoglobulin free light chains. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 1578-1583
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 1578-1583
    • Kraneveld, A.D.1
  • 11
    • 34248137929 scopus 로고    scopus 로고
    • Differential release of mast cell mediators and the pathogenesis of inflammation
    • Theoharides T.C., et al. Differential release of mast cell mediators and the pathogenesis of inflammation. Immunol. Rev. 217 (2007) 65-78
    • (2007) Immunol. Rev. , vol.217 , pp. 65-78
    • Theoharides, T.C.1
  • 12
    • 36849072350 scopus 로고    scopus 로고
    • The mast cell and allergic diseases: role in pathogenesis and implications for therapy
    • Brown J.M., et al. The mast cell and allergic diseases: role in pathogenesis and implications for therapy. Clin. Exp. Allergy 38 (2008) 4-18
    • (2008) Clin. Exp. Allergy , vol.38 , pp. 4-18
    • Brown, J.M.1
  • 13
    • 0034693950 scopus 로고    scopus 로고
    • Mast cells control neutrophil recruitment during T cell-mediated delayed-type hypersensitivity reactions through tumor necrosis factor and macrophage inflammatory protein 2
    • Biedermann T., et al. Mast cells control neutrophil recruitment during T cell-mediated delayed-type hypersensitivity reactions through tumor necrosis factor and macrophage inflammatory protein 2. J. Exp. Med. 192 (2000) 1441-1452
    • (2000) J. Exp. Med. , vol.192 , pp. 1441-1452
    • Biedermann, T.1
  • 14
    • 33846411787 scopus 로고    scopus 로고
    • Topical application of F991, an immunoglobulin free light chain antagonist, prevents development of contact sensitivity in mice
    • van Houwelingen A.H., et al. Topical application of F991, an immunoglobulin free light chain antagonist, prevents development of contact sensitivity in mice. Clin. Exp. Allergy 37 (2007) 270-275
    • (2007) Clin. Exp. Allergy , vol.37 , pp. 270-275
    • van Houwelingen, A.H.1
  • 15
    • 0037383839 scopus 로고    scopus 로고
    • Immunoglobulin free light chains and mast cells: pivotal role in T-cell-mediated immune reactions?
    • Redegeld F.A., and Nijkamp F.P. Immunoglobulin free light chains and mast cells: pivotal role in T-cell-mediated immune reactions?. Trends Immunol. 24 (2003) 181-185
    • (2003) Trends Immunol. , vol.24 , pp. 181-185
    • Redegeld, F.A.1    Nijkamp, F.P.2
  • 16
    • 0037108379 scopus 로고    scopus 로고
    • Subunits of IgM reconstitute defective contact sensitivity in B-1 cell-deficient xid mice: κ light chains recruit T cells independent of complement
    • Paliwal V., et al. Subunits of IgM reconstitute defective contact sensitivity in B-1 cell-deficient xid mice: κ light chains recruit T cells independent of complement. J. Immunol. 169 (2002) 4113-4123
    • (2002) J. Immunol. , vol.169 , pp. 4113-4123
    • Paliwal, V.1
  • 17
    • 0014353171 scopus 로고
    • Free immunoglobulin light chains in connective tissue diseases
    • Cooper A., and Bluestone R. Free immunoglobulin light chains in connective tissue diseases. Ann. Rheum. Dis. 27 (1968) 537-543
    • (1968) Ann. Rheum. Dis. , vol.27 , pp. 537-543
    • Cooper, A.1    Bluestone, R.2
  • 18
    • 0033060552 scopus 로고    scopus 로고
    • How much asthma is really attributable to atopy?
    • Pearce N., et al. How much asthma is really attributable to atopy?. Thorax 54 (1999) 268-272
    • (1999) Thorax , vol.54 , pp. 268-272
    • Pearce, N.1
  • 19
    • 0037198418 scopus 로고    scopus 로고
    • Mast-cell infiltration of airway smooth muscle in asthma
    • Brightling C.E., et al. Mast-cell infiltration of airway smooth muscle in asthma. N. Engl. J. Med. 346 (2002) 1699-1705
    • (2002) N. Engl. J. Med. , vol.346 , pp. 1699-1705
    • Brightling, C.E.1
  • 20
    • 0037103337 scopus 로고    scopus 로고
    • Key role for mast cells in nonatopic asthma
    • Kraneveld A.D., et al. Key role for mast cells in nonatopic asthma. J. Immunol. 169 (2002) 2044-2053
    • (2002) J. Immunol. , vol.169 , pp. 2044-2053
    • Kraneveld, A.D.1
  • 21
    • 33745225217 scopus 로고    scopus 로고
    • Mast cells can promote the development of multiple features of chronic asthma in mice
    • Yu M., et al. Mast cells can promote the development of multiple features of chronic asthma in mice. J. Clin. Invest. 116 (2006) 1633-1641
    • (2006) J. Clin. Invest. , vol.116 , pp. 1633-1641
    • Yu, M.1
  • 22
    • 33751119571 scopus 로고    scopus 로고
    • TNF-α is crucial for the development of mast cell-dependent colitis in mice
    • Rijnierse A., et al. TNF-α is crucial for the development of mast cell-dependent colitis in mice. Am. J. Physiol. Gastrointest. Liver Physiol. 291 (2006) G969-G976
    • (2006) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.291
    • Rijnierse, A.1
  • 23
    • 33646029749 scopus 로고    scopus 로고
    • Critical role for mast cells in the pathogenesis of 2,4-dinitrobenzene-induced murine colonic hypersensitivity reaction
    • Rijnierse A., et al. Critical role for mast cells in the pathogenesis of 2,4-dinitrobenzene-induced murine colonic hypersensitivity reaction. J. Immunol. 176 (2006) 4375-4384
    • (2006) J. Immunol. , vol.176 , pp. 4375-4384
    • Rijnierse, A.1
  • 24
    • 34548853957 scopus 로고    scopus 로고
    • Mast cells and nerves tickle in the tummy: implications for inflammatory bowel disease and irritable bowel syndrome
    • Rijnierse A., et al. Mast cells and nerves tickle in the tummy: implications for inflammatory bowel disease and irritable bowel syndrome. Pharmacol. Ther. 116 (2007) 207-235
    • (2007) Pharmacol. Ther. , vol.116 , pp. 207-235
    • Rijnierse, A.1
  • 25
    • 33846001611 scopus 로고    scopus 로고
    • Serum immunoglobulin free light chain assessment in rheumatoid arthritis and primary Sjögren's syndrome
    • Gottenberg J.E., et al. Serum immunoglobulin free light chain assessment in rheumatoid arthritis and primary Sjögren's syndrome. Ann. Rheum. Dis. 66 (2007) 23-27
    • (2007) Ann. Rheum. Dis. , vol.66 , pp. 23-27
    • Gottenberg, J.E.1
  • 26
    • 33749830743 scopus 로고    scopus 로고
    • Elevated CSF free κ light chains correlate with disability prognosis in multiple sclerosis
    • Rinker II J.R., et al. Elevated CSF free κ light chains correlate with disability prognosis in multiple sclerosis. Neurology 67 (2006) 1288-1290
    • (2006) Neurology , vol.67 , pp. 1288-1290
    • Rinker II, J.R.1
  • 27
    • 0028851791 scopus 로고
    • Cerebrospinal fluid free κ light chains versus IgG findings in neurological disorders: qualitative and quantitative measurements
    • Lamers K.J., et al. Cerebrospinal fluid free κ light chains versus IgG findings in neurological disorders: qualitative and quantitative measurements. J. Neuroimmunol. 62 (1995) 19-25
    • (1995) J. Neuroimmunol. , vol.62 , pp. 19-25
    • Lamers, K.J.1
  • 28
    • 0842265938 scopus 로고    scopus 로고
    • Detection of oligoclonal free κ chains in the absence of oligoclonal IgG in the CSF of patients with suspected multiple sclerosis
    • Goffette S., et al. Detection of oligoclonal free κ chains in the absence of oligoclonal IgG in the CSF of patients with suspected multiple sclerosis. J. Neurol. Neurosurg. Psychiatry 75 (2004) 308-310
    • (2004) J. Neurol. Neurosurg. Psychiatry , vol.75 , pp. 308-310
    • Goffette, S.1
  • 29
    • 0035161996 scopus 로고    scopus 로고
    • Inflammation and structural changes in the airways of patients with primary Sjögren's syndrome
    • Amin K., et al. Inflammation and structural changes in the airways of patients with primary Sjögren's syndrome. Respir. Med. 95 (2001) 904-910
    • (2001) Respir. Med. , vol.95 , pp. 904-910
    • Amin, K.1
  • 30
    • 0035411819 scopus 로고    scopus 로고
    • Autoimmunity in chronic urticaria and urticarial vasculitis
    • Napoli D.C., and Freeman T.M. Autoimmunity in chronic urticaria and urticarial vasculitis. Curr. Allergy Asthma Rep. 1 (2001) 329-336
    • (2001) Curr. Allergy Asthma Rep. , vol.1 , pp. 329-336
    • Napoli, D.C.1    Freeman, T.M.2
  • 31
    • 36849043756 scopus 로고    scopus 로고
    • The multitasking mast cell: positive and negative roles in the progression of autoimmunity
    • Christy A.L., and Brown M.A. The multitasking mast cell: positive and negative roles in the progression of autoimmunity. J. Immunol. 179 (2007) 2673-2679
    • (2007) J. Immunol. , vol.179 , pp. 2673-2679
    • Christy, A.L.1    Brown, M.A.2
  • 32
    • 0034467018 scopus 로고    scopus 로고
    • Mast cell activation and its relation to proinflammatory cytokine production in the rheumatoid lesion
    • Woolley D.E., and Tetlow L.C. Mast cell activation and its relation to proinflammatory cytokine production in the rheumatoid lesion. Arthritis Res. 2 (2000) 65-74
    • (2000) Arthritis Res. , vol.2 , pp. 65-74
    • Woolley, D.E.1    Tetlow, L.C.2
  • 33
    • 0019420691 scopus 로고
    • Free light chains of immunoglobulins in serum from patients with rheumatoid arthritis, sarcoidosis, chronic infections and pulmonary cancer
    • Solling K., et al. Free light chains of immunoglobulins in serum from patients with rheumatoid arthritis, sarcoidosis, chronic infections and pulmonary cancer. Acta Med. Scand. 209 (1981) 473-477
    • (1981) Acta Med. Scand. , vol.209 , pp. 473-477
    • Solling, K.1
  • 34
    • 0023805257 scopus 로고
    • Free κ and λ light chain levels in the cerebrospinal fluid of patients with multiple sclerosis and other neurological diseases
    • Fagnart O.C., et al. Free κ and λ light chain levels in the cerebrospinal fluid of patients with multiple sclerosis and other neurological diseases. J. Neuroimmunol. 19 (1988) 119-132
    • (1988) J. Neuroimmunol. , vol.19 , pp. 119-132
    • Fagnart, O.C.1
  • 35
    • 0025950025 scopus 로고
    • Increased occurrence of free immunoglobulin light chains in cerebrospinal fluid and serum in human immunodeficiency virus-1 infection
    • Elovaara I., et al. Increased occurrence of free immunoglobulin light chains in cerebrospinal fluid and serum in human immunodeficiency virus-1 infection. J. Neuroimmunol. 35 (1991) 65-77
    • (1991) J. Neuroimmunol. , vol.35 , pp. 65-77
    • Elovaara, I.1
  • 36
    • 0024431465 scopus 로고
    • Clinical relapse in systemic lupus erythematosus: correlation with antecedent elevation of urinary free light-chain immunoglobulin
    • Hopper J.E., et al. Clinical relapse in systemic lupus erythematosus: correlation with antecedent elevation of urinary free light-chain immunoglobulin. J. Clin. Immunol. 9 (1989) 338-350
    • (1989) J. Clin. Immunol. , vol.9 , pp. 338-350
    • Hopper, J.E.1
  • 37
    • 0026512138 scopus 로고
    • Increased excretion of soluble interleukin 2 receptors and free light chain immunoglobulins in the urine of patients with active lupus nephritis
    • Tsai C.Y., et al. Increased excretion of soluble interleukin 2 receptors and free light chain immunoglobulins in the urine of patients with active lupus nephritis. Ann. Rheum. Dis. 51 (1992) 168-172
    • (1992) Ann. Rheum. Dis. , vol.51 , pp. 168-172
    • Tsai, C.Y.1
  • 38
    • 0025240843 scopus 로고
    • Urinary excretion of κ light chains in patients with diabetes mellitus
    • Groop L., et al. Urinary excretion of κ light chains in patients with diabetes mellitus. Kidney Int. 37 (1990) 1120-1125
    • (1990) Kidney Int. , vol.37 , pp. 1120-1125
    • Groop, L.1
  • 39
    • 5644233966 scopus 로고    scopus 로고
    • Mast cells: the Jekyll and Hyde of tumor growth
    • Theoharides T.C., and Conti P. Mast cells: the Jekyll and Hyde of tumor growth. Trends Immunol. 25 (2004) 235-241
    • (2004) Trends Immunol. , vol.25 , pp. 235-241
    • Theoharides, T.C.1    Conti, P.2
  • 40
    • 36148964034 scopus 로고    scopus 로고
    • Role of mast cells in tumor growth
    • Conti P., et al. Role of mast cells in tumor growth. Ann. Clin. Lab. Sci. 37 (2007) 315-322
    • (2007) Ann. Clin. Lab. Sci. , vol.37 , pp. 315-322
    • Conti, P.1
  • 41
    • 33750840512 scopus 로고    scopus 로고
    • Evidence of a functional role for mast cells in the development of type 1 diabetes mellitus in the BioBreeding rat
    • Geoffrey R., et al. Evidence of a functional role for mast cells in the development of type 1 diabetes mellitus in the BioBreeding rat. J. Immunol. 177 (2006) 7275-7286
    • (2006) J. Immunol. , vol.177 , pp. 7275-7286
    • Geoffrey, R.1
  • 42
    • 0037376706 scopus 로고    scopus 로고
    • ELISAs for free light chains of human immunoglobulins using monoclonal antibodies: comparison of their specificity with available polyclonal antibodies
    • Nakano T., and Nagata A. ELISAs for free light chains of human immunoglobulins using monoclonal antibodies: comparison of their specificity with available polyclonal antibodies. J. Immunol. Methods 275 (2003) 9-17
    • (2003) J. Immunol. Methods , vol.275 , pp. 9-17
    • Nakano, T.1    Nagata, A.2
  • 43
    • 33646700777 scopus 로고    scopus 로고
    • Immunochemical quantification of free immunoglobulin light chains from an analytical perspective
    • Nakano T., et al. Immunochemical quantification of free immunoglobulin light chains from an analytical perspective. Clin. Chem. Lab. Med. 44 (2006) 522-532
    • (2006) Clin. Chem. Lab. Med. , vol.44 , pp. 522-532
    • Nakano, T.1
  • 44
    • 0034256087 scopus 로고    scopus 로고
    • Evidence of cerebrospinal fluid free κ light chains in AIDS patients with Toxoplasma gondii encephalitis
    • Contini C., et al. Evidence of cerebrospinal fluid free κ light chains in AIDS patients with Toxoplasma gondii encephalitis. J. Neuroimmunol. 108 (2000) 221-226
    • (2000) J. Neuroimmunol. , vol.108 , pp. 221-226
    • Contini, C.1
  • 45
    • 33748438946 scopus 로고    scopus 로고
    • Antigen-specific free immunoglobulin light-chain antibodies: could it be a new diagnostic marker for patients with allergy?
    • Nakano T., et al. Antigen-specific free immunoglobulin light-chain antibodies: could it be a new diagnostic marker for patients with allergy?. Clin. Biochem. 39 (2006) 955-959
    • (2006) Clin. Biochem. , vol.39 , pp. 955-959
    • Nakano, T.1
  • 46
    • 5644264939 scopus 로고    scopus 로고
    • Purification and characterization of a stimulator of plasmin generation from the antiangiogenic agent Neovastat: identification as immunoglobulin κ light chain
    • Boivin D., et al. Purification and characterization of a stimulator of plasmin generation from the antiangiogenic agent Neovastat: identification as immunoglobulin κ light chain. Arch. Biochem. Biophys. 431 (2004) 197-206
    • (2004) Arch. Biochem. Biophys. , vol.431 , pp. 197-206
    • Boivin, D.1
  • 47
    • 0028127014 scopus 로고
    • Proteolytic activity of an antibody light chain
    • Sun M., et al. Proteolytic activity of an antibody light chain. J. Immunol. 153 (1994) 5121-5126
    • (1994) J. Immunol. , vol.153 , pp. 5121-5126
    • Sun, M.1
  • 48
    • 0029072696 scopus 로고
    • Natural catalytic antibodies: peptide-hydrolyzing activities of Bence Jones proteins and VL fragment
    • Paul S., et al. Natural catalytic antibodies: peptide-hydrolyzing activities of Bence Jones proteins and VL fragment. J. Biol. Chem. 270 (1995) 15257-15261
    • (1995) J. Biol. Chem. , vol.270 , pp. 15257-15261
    • Paul, S.1
  • 49
    • 0034732941 scopus 로고    scopus 로고
    • Monoclonal antibody light chain with prothrombinase activity
    • Thiagarajan P., et al. Monoclonal antibody light chain with prothrombinase activity. Biochemistry 39 (2000) 6459-6465
    • (2000) Biochemistry , vol.39 , pp. 6459-6465
    • Thiagarajan, P.1
  • 50
    • 0032875669 scopus 로고    scopus 로고
    • Nephritogenic λ light chain dimer: a unique human miniautoantibody against complement factor H
    • Jokiranta T.S., et al. Nephritogenic λ light chain dimer: a unique human miniautoantibody against complement factor H. J. Immunol. 163 (1999) 4590-4596
    • (1999) J. Immunol. , vol.163 , pp. 4590-4596
    • Jokiranta, T.S.1
  • 51
    • 0021806879 scopus 로고
    • Binding of N-formylated chemotactic peptides in crystals of the Mcg light chain dimer: similarities with neutrophil receptors
    • Edmundson A.B., and Ely K.R. Binding of N-formylated chemotactic peptides in crystals of the Mcg light chain dimer: similarities with neutrophil receptors. Mol. Immunol. 22 (1985) 463-475
    • (1985) Mol. Immunol. , vol.22 , pp. 463-475
    • Edmundson, A.B.1    Ely, K.R.2
  • 52
    • 0023226209 scopus 로고
    • The binding of opioid peptides to the Mcg light chain dimer: flexible keys and adjustable locks
    • Edmundson A.B., et al. The binding of opioid peptides to the Mcg light chain dimer: flexible keys and adjustable locks. Mol. Immunol. 24 (1987) 915-935
    • (1987) Mol. Immunol. , vol.24 , pp. 915-935
    • Edmundson, A.B.1
  • 53
    • 0033377748 scopus 로고    scopus 로고
    • Recombinant light chain of human monoclonal antibody HB4C5 as a potentially useful lung cancer-targeting vehicle
    • Nishimura E., et al. Recombinant light chain of human monoclonal antibody HB4C5 as a potentially useful lung cancer-targeting vehicle. Hum. Antibodies 9 (1999) 111-124
    • (1999) Hum. Antibodies , vol.9 , pp. 111-124
    • Nishimura, E.1
  • 54
    • 0142080390 scopus 로고    scopus 로고
    • Domain antibodies: proteins for therapy
    • Holt L.J., et al. Domain antibodies: proteins for therapy. Trends Biotechnol. 21 (2003) 484-490
    • (2003) Trends Biotechnol. , vol.21 , pp. 484-490
    • Holt, L.J.1
  • 55
    • 19944395483 scopus 로고    scopus 로고
    • Potent inhibition of huntingtin aggregation and cytotoxicity by a disulfide bond-free single-domain intracellular antibody
    • Colby D.W., et al. Potent inhibition of huntingtin aggregation and cytotoxicity by a disulfide bond-free single-domain intracellular antibody. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 17616-17621
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 17616-17621
    • Colby, D.W.1
  • 56
    • 0035854524 scopus 로고    scopus 로고
    • Building novel binding ligands to B7.1 and B7.2 based on human antibody single variable light chain domains
    • van den Beucken T., et al. Building novel binding ligands to B7.1 and B7.2 based on human antibody single variable light chain domains. J. Mol. Biol. 310 (2001) 591-601
    • (2001) J. Mol. Biol. , vol.310 , pp. 591-601
    • van den Beucken, T.1
  • 57
    • 0036433583 scopus 로고    scopus 로고
    • Endocytosis of light chains induces cytokines through activation of NF-κB in human proximal tubule cells
    • Sengul S., et al. Endocytosis of light chains induces cytokines through activation of NF-κB in human proximal tubule cells. Kidney Int. 62 (2002) 1977-1988
    • (2002) Kidney Int. , vol.62 , pp. 1977-1988
    • Sengul, S.1
  • 58
    • 0032750718 scopus 로고    scopus 로고
    • Protein overload activates proximal tubular cells to release vasoactive and inflammatory mediators
    • Zoja C., et al. Protein overload activates proximal tubular cells to release vasoactive and inflammatory mediators. Exp. Nephrol. 7 (1999) 420-428
    • (1999) Exp. Nephrol. , vol.7 , pp. 420-428
    • Zoja, C.1
  • 59
    • 2342459810 scopus 로고    scopus 로고
    • Different types of glomerulopathic light chains interact with mesangial cells using a common receptor but exhibit different intracellular trafficking patterns
    • Teng J., et al. Different types of glomerulopathic light chains interact with mesangial cells using a common receptor but exhibit different intracellular trafficking patterns. Lab. Invest. 84 (2004) 440-451
    • (2004) Lab. Invest. , vol.84 , pp. 440-451
    • Teng, J.1
  • 60
    • 0001935006 scopus 로고    scopus 로고
    • A study of the interactions of an immunoglobulin light chain with artificial and B-lymphocyte membranes
    • Wall J.S., et al. A study of the interactions of an immunoglobulin light chain with artificial and B-lymphocyte membranes. Front. Biosci. 1 (1996) a46-a58
    • (1996) Front. Biosci. , vol.1
    • Wall, J.S.1
  • 61
    • 0035478439 scopus 로고    scopus 로고
    • Association of B lymphocyte antigen receptor polypeptides with multiple chaperone proteins
    • Foy S.P., and Matsuuchi L. Association of B lymphocyte antigen receptor polypeptides with multiple chaperone proteins. Immunol. Lett. 78 (2001) 149-160
    • (2001) Immunol. Lett. , vol.78 , pp. 149-160
    • Foy, S.P.1    Matsuuchi, L.2
  • 62
    • 33947183940 scopus 로고    scopus 로고
    • Conventional light chains inhibit the autonomous signaling capacity of the B cell receptor
    • Meixlsperger S., et al. Conventional light chains inhibit the autonomous signaling capacity of the B cell receptor. Immunity 26 (2007) 323-333
    • (2007) Immunity , vol.26 , pp. 323-333
    • Meixlsperger, S.1
  • 63
    • 1342329593 scopus 로고    scopus 로고
    • Mast cells and eosinophils: the hallmark of asthma
    • Puxeddu I., and Levi-Schaffer F. Mast cells and eosinophils: the hallmark of asthma. Paediatr. Respir. Rev. 5 Suppl. A (2004) S31-S34
    • (2004) Paediatr. Respir. Rev. , vol.5 , Issue.SUPPL. A
    • Puxeddu, I.1    Levi-Schaffer, F.2
  • 64
    • 0036720993 scopus 로고    scopus 로고
    • Serum reference intervals and diagnostic ranges for free κ and free λ immunoglobulin light chains: relative sensitivity for detection of monoclonal light chains
    • Katzmann J.A., et al. Serum reference intervals and diagnostic ranges for free κ and free λ immunoglobulin light chains: relative sensitivity for detection of monoclonal light chains. Clin. Chem. 48 (2002) 1437-1444
    • (2002) Clin. Chem. , vol.48 , pp. 1437-1444
    • Katzmann, J.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.