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Volumn 44, Issue 5, 2006, Pages 522-532

Immunochemical quantification of free immunoglobulin light chains from an analytical perspective

Author keywords

Antibody; Bence Jones protein; Free immunoglobulin light chain; Immunoassay; Standardization

Indexed keywords

ANTIBODY; IMMUNOGLOBULIN LIGHT CHAIN;

EID: 33646700777     PISSN: 14346621     EISSN: 14346621     Source Type: Journal    
DOI: 10.1515/CCLM.2006.118     Document Type: Review
Times cited : (37)

References (73)
  • 1
    • 0001959377 scopus 로고
    • Papers on chemical pathology: Lecture III
    • Bence Jones H. Papers on chemical pathology: lecture III. Lancet 1847;ii:88-92.
    • (1847) Lancet , vol.2 , pp. 88-92
    • Bence Jones, H.1
  • 2
    • 73049153504 scopus 로고
    • The nature of Bence-Jones proteins. Chemical similarities to polypetide chains of myeloma globulins and normal gamma-globulins
    • Edelman GM, Gally JA. The nature of Bence-Jones proteins. Chemical similarities to polypetide chains of myeloma globulins and normal gamma-globulins. J Exp Med 1962;116:207-27.
    • (1962) J Exp Med , vol.116 , pp. 207-227
    • Edelman, G.M.1    Gally, J.A.2
  • 4
    • 0037256725 scopus 로고    scopus 로고
    • Guidelines for the analysis of Bence Jones protein
    • Graziani M, Merlini G, Petrini C. Guidelines for the analysis of Bence Jones protein. Clin Chem Lab Med 2003;41:338-46.
    • (2003) Clin Chem Lab Med , vol.41 , pp. 338-346
    • Graziani, M.1    Merlini, G.2    Petrini, C.3
  • 5
    • 0033035886 scopus 로고    scopus 로고
    • Electrophoretic analysis of Bence Jones proteinuria
    • Marshall T, Williams KM. Electrophoretic analysis of Bence Jones proteinuria. Electrophoresis 1999;20:1307-24.
    • (1999) Electrophoresis , vol.20 , pp. 1307-1324
    • Marshall, T.1    Williams, K.M.2
  • 6
    • 0028125256 scopus 로고
    • Free light chains of immunoglobulins: Clinical laboratory analysis
    • Levinson SS, Keren DF. Free light chains of immunoglobulins: clinical laboratory analysis. Clin Chem 1994;40:1869-78.
    • (1994) Clin Chem , vol.40 , pp. 1869-1878
    • Levinson, S.S.1    Keren, D.F.2
  • 7
    • 0025278422 scopus 로고
    • The optimum urine collections for the detection and monitoring of Bence Jones proteinuria
    • Brigden ML, Neal ED, McNeely MD, Hoag GN. The optimum urine collections for the detection and monitoring of Bence Jones proteinuria. Am J Clin Pathol 1990;93:689-93.
    • (1990) Am J Clin Pathol , vol.93 , pp. 689-693
    • Brigden, M.L.1    Neal, E.D.2    McNeely, M.D.3    Hoag, G.N.4
  • 8
    • 0024385281 scopus 로고
    • Evaluation and optimization of variables in immunofixation electrophoresis for the detection of IgG paraproteins
    • Monos DS, Bina M, Kahn SN. Evaluation and optimization of variables in immunofixation electrophoresis for the detection of IgG paraproteins. Clin Biochem 1989;22:369-71.
    • (1989) Clin Biochem , vol.22 , pp. 369-371
    • Monos, D.S.1    Bina, M.2    Kahn, S.N.3
  • 9
    • 0013665017 scopus 로고
    • A direct immunologic assay of human sera for Bence Jones proteins (L-chains)
    • Tan M, Epstein WV. A direct immunologic assay of human sera for Bence Jones proteins (L-chains). J Lab Clin Med 1965;66:344-56.
    • (1965) J Lab Clin Med , vol.66 , pp. 344-356
    • Tan, M.1    Epstein, W.V.2
  • 10
    • 0019962340 scopus 로고
    • Free light chains of immunoglobulins in serum from patients with leukaemias and multiple myeloma
    • Sölling K, Nielsen JL, Sölling J, Ellegaard J. Free light chains of immunoglobulins in serum from patients with leukaemias and multiple myeloma. Scand J Haematol 1982;28:309-18.
    • (1982) Scand J Haematol , vol.28 , pp. 309-318
    • Sölling, K.1    Nielsen, J.L.2    Sölling, J.3    Ellegaard, J.4
  • 11
    • 0019902440 scopus 로고
    • Myeloma protein kinetics following chemotherapy
    • McLaughlin P, Alexanian R. Myeloma protein kinetics following chemotherapy. Blood 1982;60:851-5.
    • (1982) Blood , vol.60 , pp. 851-855
    • McLaughlin, P.1    Alexanian, R.2
  • 12
    • 0035063345 scopus 로고    scopus 로고
    • Highly sensitive, automated immunoassay for immunoglobulin free light chains in serum and urine
    • Bradwell AR, Carr-Smith HD, Mead GP, Tang LX, Showell PJ, Drayson MT, et al. Highly sensitive, automated immunoassay for immunoglobulin free light chains in serum and urine. Clin Chem 2001;47:673-80.
    • (2001) Clin Chem , vol.47 , pp. 673-680
    • Bradwell, A.R.1    Carr-Smith, H.D.2    Mead, G.P.3    Tang, L.X.4    Showell, P.J.5    Drayson, M.T.6
  • 14
    • 17744370515 scopus 로고    scopus 로고
    • Diagnostic performance of quantitative κ and λ free light chain assays in clinical practice
    • Katzmann JA, Abraham RS, Dispenzieri A, Lust JA, Kyle RA. Diagnostic performance of quantitative κ and λ free light chain assays in clinical practice. Clin Chem 2005;51:878-81.
    • (2005) Clin Chem , vol.51 , pp. 878-881
    • Katzmann, J.A.1    Abraham, R.S.2    Dispenzieri, A.3    Lust, J.A.4    Kyle, R.A.5
  • 15
    • 17744382676 scopus 로고    scopus 로고
    • Definition of organ involvement and treatment response in primary systemic amyloidosis (AL): A consensus opinion from the 10th International Symposium on Amyloid and Amyloidosis
    • Gateau G, Kyle RA, Skinner M, editors. Boca Raton, FL: CRC Press
    • Gertz MA, Commenzo R, Falk RH, Fermand JP, Hazenberg BP, Hawkins PN. Definition of organ involvement and treatment response in primary systemic amyloidosis (AL): a consensus opinion from the 10th International Symposium on Amyloid and Amyloidosis. In: Gateau G, Kyle RA, Skinner M, editors. Amyloid and amyloidosis. Boca Raton, FL: CRC Press, 2004:151-3.
    • (2004) Amyloid and Amyloidosis , pp. 151-153
    • Gertz, M.A.1    Commenzo, R.2    Falk, R.H.3    Fermand, J.P.4    Hazenberg, B.P.5    Hawkins, P.N.6
  • 16
    • 0041866804 scopus 로고    scopus 로고
    • Practical considerations for the measurement of free light chains in serum
    • Tate JR, Gill D, Cobcroft R, Hickman PE. Practical considerations for the measurement of free light chains in serum. Clin Chem 2003;49:1252-7.
    • (2003) Clin Chem , vol.49 , pp. 1252-1257
    • Tate, J.R.1    Gill, D.2    Cobcroft, R.3    Hickman, P.E.4
  • 17
    • 7944219598 scopus 로고    scopus 로고
    • ELISAs for free human immunoglobulin light chains in serum: Improvement of assay specificity by using two specific antibodies in a sandwich detection method
    • Nakano T, Nagata A. ELISAs for free human immunoglobulin light chains in serum: improvement of assay specificity by using two specific antibodies in a sandwich detection method. J Immunol Methods 2004;293:183-9.
    • (2004) J Immunol Methods , vol.293 , pp. 183-189
    • Nakano, T.1    Nagata, A.2
  • 18
    • 0019738951 scopus 로고
    • Free light chains of immunoglobulins
    • Sölling K. Free light chains of immunoglobulins. Scand J Clin Lab Invest Suppl 1981;157:1-83.
    • (1981) Scand J Clin Lab Invest Suppl , vol.157 , pp. 1-83
    • Sölling, K.1
  • 19
    • 17744396910 scopus 로고    scopus 로고
    • Serum free light chain measurements move to center stage
    • Bradwell AR. Serum free light chain measurements move to center stage. Clin Chem 2005;51:805-7.
    • (2005) Clin Chem , vol.51 , pp. 805-807
    • Bradwell, A.R.1
  • 20
    • 0014356679 scopus 로고
    • Serum and urine light chain levels in benign monoclonal gammapathies, multiple myeloma and Waldenström's macroglobulinaemia
    • Dammacco F, Waldenström J. Serum and urine light chain levels in benign monoclonal gammapathies, multiple myeloma and Waldenström's macroglobulinaemia. Clin Exp Immunol 1968;3:911-21.
    • (1968) Clin Exp Immunol , vol.3 , pp. 911-921
    • Dammacco, F.1    Waldenström, J.2
  • 21
    • 0014480833 scopus 로고
    • Use of insoluble antibody for quantitative determination of small amounts of immunoglobulin
    • Mann D, Granger H, Fahey JL. Use of insoluble antibody for quantitative determination of small amounts of immunoglobulin. J Immunol 1969;102:618-24.
    • (1969) J Immunol , vol.102 , pp. 618-624
    • Mann, D.1    Granger, H.2    Fahey, J.L.3
  • 22
    • 85105423700 scopus 로고
    • Urinary immunoglobulin components in normal, tubular, and glomerular proteinuria: Quantities and characteristics of free light chains, IgG, IgA, and Fc-gamma fragment
    • Peterson PA, Berggård I. Urinary immunoglobulin components in normal, tubular, and glomerular proteinuria: quantities and characteristics of free light chains, IgG, IgA, and Fc-gamma fragment. Eur J Clin Invest 1971;1:255-64.
    • (1971) Eur J Clin Invest , vol.1 , pp. 255-264
    • Peterson, P.A.1    Berggård, I.2
  • 23
    • 0016217353 scopus 로고
    • Evidence for defective immunoglobulin metabolism in severe renal insufficiency
    • Abraham GN, Waterhouse C. Evidence for defective immunoglobulin metabolism in severe renal insufficiency. Am J Med Sci 1974;268:227-33.
    • (1974) Am J Med Sci , vol.268 , pp. 227-233
    • Abraham, G.N.1    Waterhouse, C.2
  • 24
    • 0016826844 scopus 로고
    • Free light chains of immunoglobulins in normal serum and urine determined by radioimmunoassay
    • Sölling K. Free light chains of immunoglobulins in normal serum and urine determined by radioimmunoassay. Scand J Clin Lab Invest 1975;35:407-12.
    • (1975) Scand J Clin Lab Invest , vol.35 , pp. 407-412
    • Sölling, K.1
  • 25
    • 0017581378 scopus 로고
    • Urinary excretion of ten plasma proteins in patients with febrile diseases
    • Hemmingsen L, Skaarup P. Urinary excretion of ten plasma proteins in patients with febrile diseases. Acta Med Scand 1977;201:359-64.
    • (1977) Acta Med Scand , vol.201 , pp. 359-364
    • Hemmingsen, L.1    Skaarup, P.2
  • 26
    • 0017849127 scopus 로고
    • Immunoquantitation of free light chain immunoglobulins: Applications in multiple myeloma
    • Cole PW, Durie BG, Salmon SE. Immunoquantitation of free light chain immunoglobulins: applications in multiple myeloma. J Immunol Methods 1978;19:341-9.
    • (1978) J Immunol Methods , vol.19 , pp. 341-349
    • Cole, P.W.1    Durie, B.G.2    Salmon, S.E.3
  • 27
    • 0020470654 scopus 로고
    • Radioimmunoassay of free light chains of immunoglobulins in urine
    • Robinson EL, Gowland E, Ward ID, Scarffe JH. Radioimmunoassay of free light chains of immunoglobulins in urine. Clin Chem 1982;28:2254-8.
    • (1982) Clin Chem , vol.28 , pp. 2254-2258
    • Robinson, E.L.1    Gowland, E.2    Ward, I.D.3    Scarffe, J.H.4
  • 29
    • 0020629308 scopus 로고
    • Serum-free light chain analysis by crossed immunoelectrophoresis: Correlation with plasmapheresis in light chain disease nephropathy
    • McLeod BC, Viernes AL, Sassetti RJ. Serum-free light chain analysis by crossed immunoelectrophoresis: correlation with plasmapheresis in light chain disease nephropathy. Am J Hematol 1983;15:75-88.
    • (1983) Am J Hematol , vol.15 , pp. 75-88
    • McLeod, B.C.1    Viernes, A.L.2    Sassetti, R.J.3
  • 31
    • 0021933155 scopus 로고
    • Multiple sclerosis: Free light chains in cerebrospinal fluid
    • Rudick RA, Peter DR, Bidlack JM, Knutson DW. Multiple sclerosis: free light chains in cerebrospinal fluid. Neurology 1985;35:1443-9.
    • (1985) Neurology , vol.35 , pp. 1443-1449
    • Rudick, R.A.1    Peter, D.R.2    Bidlack, J.M.3    Knutson, D.W.4
  • 32
    • 0021811861 scopus 로고
    • Urinary excretion of plasma proteins in diabetic subjects. Increased excretion of kappa light chains in diabetic patients with and without proliferative retinopathy
    • Teppo AM, Groop L. Urinary excretion of plasma proteins in diabetic subjects. Increased excretion of kappa light chains in diabetic patients with and without proliferative retinopathy. Diabetes 1985;34:589-94.
    • (1985) Diabetes , vol.34 , pp. 589-594
    • Teppo, A.M.1    Groop, L.2
  • 33
    • 0023264107 scopus 로고
    • Quantitation of free κ light chains in serum and urine using a monoclonal antibody based inhibition enzyme-linked immunoassay
    • Axiak SM, Krishnamoorthy L, Guinan J, Raison RL. Quantitation of free κ light chains in serum and urine using a monoclonal antibody based inhibition enzyme-linked immunoassay. J Immunol Methods 1987;99:141-7.
    • (1987) J Immunol Methods , vol.99 , pp. 141-147
    • Axiak, S.M.1    Krishnamoorthy, L.2    Guinan, J.3    Raison, R.L.4
  • 34
    • 0023805257 scopus 로고
    • Free kappa and lambda light chain levels in the cerebrospinal fluid of patients with multiple sclerosis and other neurological diseases
    • Fagnart OC, Sindic CJ, Laterre C. Free kappa and lambda light chain levels in the cerebrospinal fluid of patients with multiple sclerosis and other neurological diseases. J Neuroimmunol 1988;19:119-32.
    • (1988) J Neuroimmunol , vol.19 , pp. 119-132
    • Fagnart, O.C.1    Sindic, C.J.2    Laterre, C.3
  • 35
    • 0024412697 scopus 로고
    • Measurement of free kappa immunoglobulin light chains in the cerebrospinal fluid by a competitive avidin-biotin ELISA
    • Lolli F, Amaducci L. Measurement of free kappa immunoglobulin light chains in the cerebrospinal fluid by a competitive avidin-biotin ELISA. Clin Chim Acta 1989;182:229-34.
    • (1989) Clin Chim Acta , vol.182 , pp. 229-234
    • Lolli, F.1    Amaducci, L.2
  • 36
    • 0025780512 scopus 로고
    • Increased free light chains in the urine from patients with multiple sclerosis
    • Mehta PD, Cook SD, Troiano RA, Coyle PK. Increased free light chains in the urine from patients with multiple sclerosis. Neurology 1991;41:540-4.
    • (1991) Neurology , vol.41 , pp. 540-544
    • Mehta, P.D.1    Cook, S.D.2    Troiano, R.A.3    Coyle, P.K.4
  • 37
    • 0025803858 scopus 로고
    • Sensitive competitive-binding ELISAs for quantifying free kappa and lambda light chains in cerebrospinal fluid
    • Stanescu GL, Swick AR, Tuohy VK, Rudick RA. Sensitive competitive-binding ELISAs for quantifying free kappa and lambda light chains in cerebrospinal fluid. J Clin Lab Anal 1991;5:206-11.
    • (1991) J Clin Lab Anal , vol.5 , pp. 206-211
    • Stanescu, G.L.1    Swick, A.R.2    Tuohy, V.K.3    Rudick, R.A.4
  • 38
    • 0025884695 scopus 로고
    • Immunoturbidimetric assay for estimating free light chains of immunoglobulins in urine and serum
    • Tillyer CR, Iqbal J, Raymond J, Gore M, McIlwain TJ. Immunoturbidimetric assay for estimating free light chains of immunoglobulins in urine and serum. J Clin Pathol 1991;44:466-71.
    • (1991) J Clin Pathol , vol.44 , pp. 466-471
    • Tillyer, C.R.1    Iqbal, J.2    Raymond, J.3    Gore, M.4    McIlwain, T.J.5
  • 40
    • 0026696770 scopus 로고
    • Measurement of free kappa and lambda chains in serum and the significance of their ratio in patients with multiple myeloma
    • Nelson M, Brown RD, Gibson J, Joshua DE. Measurement of free kappa and lambda chains in serum and the significance of their ratio in patients with multiple myeloma. Br J Haematol 1992;81:223-30.
    • (1992) Br J Haematol , vol.81 , pp. 223-230
    • Nelson, M.1    Brown, R.D.2    Gibson, J.3    Joshua, D.E.4
  • 42
    • 33646671937 scopus 로고    scopus 로고
    • Determination of free light chain in urine by latex immunoassay
    • Ohtani K, Mashiko T, Jimbo S, Ohtani H. Determination of free light chain in urine by latex immunoassay. Kitasato Med 1997;27:33-26.
    • (1997) Kitasato Med , vol.27 , pp. 33-126
    • Ohtani, K.1    Mashiko, T.2    Jimbo, S.3    Ohtani, H.4
  • 43
  • 44
    • 0037376706 scopus 로고    scopus 로고
    • ELISAs for free light chains of human immunoglobulins using monoclonal antibodies: Comparison of their specificity with available polyclonal antibodies
    • Nakano T, Nagata A. ELISAs for free light chains of human immunoglobulins using monoclonal antibodies: comparison of their specificity with available polyclonal antibodies. J Immunol Methods 2003;275:9-17.
    • (2003) J Immunol Methods , vol.275 , pp. 9-17
    • Nakano, T.1    Nagata, A.2
  • 45
    • 0013958519 scopus 로고
    • Increase of L-chain proteins in the sera of patients with systemic lupus erythematosus and the synovial fluids of patients with peripheral rheumatoid arthritis
    • Epstein WV, Tan M. Increase of L-chain proteins in the sera of patients with systemic lupus erythematosus and the synovial fluids of patients with peripheral rheumatoid arthritis. Arthritis Rheum 1966;9:713-9.
    • (1966) Arthritis Rheum , vol.9 , pp. 713-719
    • Epstein, W.V.1    Tan, M.2
  • 46
    • 0014353171 scopus 로고
    • Free immunoglobulin light chains in connective tissue diseases
    • Cooper A, Bluestone R. Free immunoglobulin light chains in connective tissue diseases. Ann Rheum Dis 1968;27:537-43.
    • (1968) Ann Rheum Dis , vol.27 , pp. 537-543
    • Cooper, A.1    Bluestone, R.2
  • 47
    • 0036816931 scopus 로고    scopus 로고
    • Urinary free light chain analysis by the Freelite immunoassay: A preliminary study in multiple myeloma
    • Le Bricon T, Bengoufa D, Benlakehal M, Bousquet B, Erlich D. Urinary free light chain analysis by the Freelite immunoassay: a preliminary study in multiple myeloma. Clin Biochem 2002;35:565-7.
    • (2002) Clin Biochem , vol.35 , pp. 565-567
    • Le Bricon, T.1    Bengoufa, D.2    Benlakehal, M.3    Bousquet, B.4    Erlich, D.5
  • 48
    • 0026582793 scopus 로고
    • Studies of Bence Jones proteins by immunonephelometry
    • Levinson SS. Studies of Bence Jones proteins by immunonephelometry. Ann Clin Lab Sci 1992;22:100-9.
    • (1992) Ann Clin Lab Sci , vol.22 , pp. 100-109
    • Levinson, S.S.1
  • 49
    • 0025016992 scopus 로고
    • Identification and quantification of Bence-Jones proteinuria by automated nephelometric screening
    • Boege F, Koehler B, Liebermann F. Identification and quantification of Bence-Jones proteinuria by automated nephelometric screening. J Clin Chem Clin Biochem 1990;28:37-42.
    • (1990) J Clin Chem Clin Biochem , vol.28 , pp. 37-42
    • Boege, F.1    Koehler, B.2    Liebermann, F.3
  • 50
    • 2342504616 scopus 로고    scopus 로고
    • Ratio of urinary free immunoglobulin light chain κ to λ in the diagnosis of Bence Jones proteinuria
    • Nakano T, Nagata A, Takahashi H. Ratio of urinary free immunoglobulin light chain κ to λ in the diagnosis of Bence Jones proteinuria. Clin Chem Lab Med 2004;42:429-34.
    • (2004) Clin Chem Lab Med , vol.42 , pp. 429-434
    • Nakano, T.1    Nagata, A.2    Takahashi, H.3
  • 51
  • 52
    • 0027200364 scopus 로고
    • Production and immunodiagnostic applications of antihuman light chain monoclonal antibodies
    • Abe M, Goto T, Kennel SJ, Wolfenbarger D, Macy SD, Weiss DT, et al. Production and immunodiagnostic applications of antihuman light chain monoclonal antibodies. Am J Clin Pathol 1993;100:67-74.
    • (1993) Am J Clin Pathol , vol.100 , pp. 67-74
    • Abe, M.1    Goto, T.2    Kennel, S.J.3    Wolfenbarger, D.4    Macy, S.D.5    Weiss, D.T.6
  • 53
    • 0027999282 scopus 로고
    • Identification and quantitation of human urine proteins by capillary electrophoresis
    • Jenkins MA, O'Leary TD, Guerin MD. Identification and quantitation of human urine proteins by capillary electrophoresis. J Chromatogr B Biomed Appl 1994;662:108-12.
    • (1994) J Chromatogr B Biomed Appl , vol.662 , pp. 108-112
    • Jenkins, M.A.1    O'Leary, T.D.2    Guerin, M.D.3
  • 54
    • 0031665605 scopus 로고    scopus 로고
    • Prospective study of serum protein capillary zone electrophoresis and immunotyping of monoclonal proteins by immunosubtraction
    • Katzmann JA, Clark R, Sanders E, Landers JP, Kyle RA. Prospective study of serum protein capillary zone electrophoresis and immunotyping of monoclonal proteins by immunosubtraction. Am J Clin Pathol 1998;110:503-9.
    • (1998) Am J Clin Pathol , vol.110 , pp. 503-509
    • Katzmann, J.A.1    Clark, R.2    Sanders, E.3    Landers, J.P.4    Kyle, R.A.5
  • 56
    • 0037277472 scopus 로고    scopus 로고
    • Detection of Bence Jones myeloma and monitoring of myeloma chemotherapy using immunoassays specific for free immunoglobulin light chains
    • Mead GP, Carr-Smith HD, Drayson MT, Bradwell AR. Detection of Bence Jones myeloma and monitoring of myeloma chemotherapy using immunoassays specific for free immunoglobulin light chains. Clin Lab 2003;49:25-7.
    • (2003) Clin Lab , vol.49 , pp. 25-27
    • Mead, G.P.1    Carr-Smith, H.D.2    Drayson, M.T.3    Bradwell, A.R.4
  • 57
    • 0035353192 scopus 로고    scopus 로고
    • Serum free light-chain measurements for identifying and monitoring patients with nonsecretory multiple myeloma
    • Drayson M, Tang LX, Drew R, Mead GP, Carr-Smith H, Bradwell AR. Serum free light-chain measurements for identifying and monitoring patients with nonsecretory multiple myeloma. Blood 2001;97:2900-2.
    • (2001) Blood , vol.97 , pp. 2900-2902
    • Drayson, M.1    Tang, L.X.2    Drew, R.3    Mead, G.P.4    Carr-Smith, H.5    Bradwell, A.R.6
  • 58
    • 0034781614 scopus 로고    scopus 로고
    • Measurement of free light chains in urine
    • Graziani MS, Merlini G. Measurement of free light chains in urine. Clin Chem 2001;47:2069-70.
    • (2001) Clin Chem , vol.47 , pp. 2069-2070
    • Graziani, M.S.1    Merlini, G.2
  • 59
    • 0021325122 scopus 로고
    • Turbidimetric measurement of Bence-Jones proteins using antibodies against free light chains of immunoglobulins. An artifact caused by different polymeric forms of light chains
    • Heino J, Rajamaki A, Irjala K. Turbidimetric measurement of Bence-Jones proteins using antibodies against free light chains of immunoglobulins. An artifact caused by different polymeric forms of light chains. Scand J Clin Lab Invest 1984;44:173-6.
    • (1984) Scand J Clin Lab Invest , vol.44 , pp. 173-176
    • Heino, J.1    Rajamaki, A.2    Irjala, K.3
  • 60
    • 0016998398 scopus 로고
    • Polymeric forms of free light chains in serum from normal individuals and from patients with renal diseases
    • Sölling K. Polymeric forms of free light chains in serum from normal individuals and from patients with renal diseases. Scand J Clin Lab Invest 1976;36:447-52.
    • (1976) Scand J Clin Lab Invest , vol.36 , pp. 447-452
    • Sölling, K.1
  • 63
    • 0032914224 scopus 로고    scopus 로고
    • Sequence of testing for monoclonal gammopathies
    • Kyle RA. Sequence of testing for monoclonal gammopathies. Arch Pathol Lab Med 1999;123:114-8.
    • (1999) Arch Pathol Lab Med , vol.123 , pp. 114-118
    • Kyle, R.A.1
  • 65
    • 0026596927 scopus 로고
    • Over- and underestimation of monoclonal gammopathies by quantification of κ- and λ-containing immunoglobulins in serum
    • Bush D, Keren DF. Over- and underestimation of monoclonal gammopathies by quantification of κ- and λ-containing immunoglobulins in serum. Clin Chem 1992;38:315-6.
    • (1992) Clin Chem , vol.38 , pp. 315-316
    • Bush, D.1    Keren, D.F.2
  • 66
    • 0025832837 scopus 로고
    • Overestimation of monoclonal immunoglobulin by immunochemical methods
    • Riches PG, Sheldon J, Smith AM, Hobbs JR. Overestimation of monoclonal immunoglobulin by immunochemical methods. Ann Clin Biochem 1991;28:253-9.
    • (1991) Ann Clin Biochem , vol.28 , pp. 253-259
    • Riches, P.G.1    Sheldon, J.2    Smith, A.M.3    Hobbs, J.R.4
  • 67
    • 0018234655 scopus 로고
    • Paraprotein estimation: A comparison of immunochemical and densitometric techniques
    • Smith AM, Thompson RA. Paraprotein estimation: a comparison of immunochemical and densitometric techniques. J Clin Pathol 1978;31:1156-60.
    • (1978) J Clin Pathol , vol.31 , pp. 1156-1160
    • Smith, A.M.1    Thompson, R.A.2
  • 68
    • 0016710360 scopus 로고
    • The 24-h excretion of plasma proteins in the urine of apparently healthy subjects
    • Hemmingsen L, Skaarup P. The 24-h excretion of plasma proteins in the urine of apparently healthy subjects. Scand J Clin Lab Invest 1975;35:347-53.
    • (1975) Scand J Clin Lab Invest , vol.35 , pp. 347-353
    • Hemmingsen, L.1    Skaarup, P.2
  • 69
    • 0025240843 scopus 로고
    • Urinary excretion of kappa light chains in patients with diabetes mellitus
    • Groop L, Makipernaa A, Stenman S, DeFronzo RA, Teppo AM. Urinary excretion of kappa light chains in patients with diabetes mellitus. Kidney Int 1990;37:1120-5.
    • (1990) Kidney Int , vol.37 , pp. 1120-1125
    • Groop, L.1    Makipernaa, A.2    Stenman, S.3    DeFronzo, R.A.4    Teppo, A.M.5
  • 70
    • 33646707482 scopus 로고    scopus 로고
    • Clinical significance of free light chain in urine by latex agglutination immunoassay
    • Ohtani S, Ohtani H. Clinical significance of free light chain in urine by latex agglutination immunoassay. Kitasato Med 1998;28:435-45.
    • (1998) Kitasato Med , vol.28 , pp. 435-445
    • Ohtani, S.1    Ohtani, H.2
  • 71
    • 0036720993 scopus 로고    scopus 로고
    • Serum reference intervals and diagnostic ranges for free κ and free λ immunoglobulin light chains: Relative sensitivity for detection of monoclonal light chains
    • Katzmann JA, Clark RJ, Abraham RS, Bryant S, Lymp JF, Bradwell AR, et al. Serum reference intervals and diagnostic ranges for free κ and free λ immunoglobulin light chains: relative sensitivity for detection of monoclonal light chains. Clin Chem 2002;48:1437-44.
    • (2002) Clin Chem , vol.48 , pp. 1437-1444
    • Katzmann, J.A.1    Clark, R.J.2    Abraham, R.S.3    Bryant, S.4    Lymp, J.F.5    Bradwell, A.R.6
  • 72
    • 0017592808 scopus 로고
    • Normal values for free light chains in serum different age groups
    • Sölling K. Normal values for free light chains in serum different age groups. Scand J Clin Lab Invest 1977;37:21-5.
    • (1977) Scand J Clin Lab Invest , vol.37 , pp. 21-25
    • Sölling, K.1
  • 73
    • 0015380362 scopus 로고
    • The renal handling of low molecular weight proteins. II. Disorders of serum protein catabolism in patients with tubular proteinuria, the nephrotic syndrome, or uremia
    • Waldmann TA, Strober W, Mogielnicki RP. The renal handling of low molecular weight proteins. II. Disorders of serum protein catabolism in patients with tubular proteinuria, the nephrotic syndrome, or uremia. J Clin Invest 1972;51:2162-74.
    • (1972) J Clin Invest , vol.51 , pp. 2162-2174
    • Waldmann, T.A.1    Strober, W.2    Mogielnicki, R.P.3


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