Non-dioxin-like polychlorinated biphenyls induce a release of arachidonic acid in liver epithelial cells: A partial role of cytosolic phospholipase A2 and extracellular signal-regulated kinases 1/2 signalling

Toxicology

Volumn 247, Issue 1, 2008, Pages 55-60

  Umannova L ^a,b   Neca J ^b   Andrysik Z ^a   Vondracek J ^a,b   Upham, B L ^c   Trosko, J E ^c   Hofmanova J ^a,d   Kozubik A ^a,d   Machala, M ^b  

^a INSTITUTE OF BIOPHYSICS   (Czech Republic)

^b VETERINARY RESEARCH INSTITUTE   (Czech Republic)

^c MICHIGAN STATE UNIVERSITY   (United States)

^d MASARYK UNIVERSITY   (Czech Republic)

Author keywords

Aryl hydrocarbon receptor; Contact inhibition; Gap junctional intercellular communication; Genotoxicity; Polychlorinated biphenyls; Rat liver epithelial cells

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 3,3',4,4',5 PENTACHLOROBIPHENYL; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ARACHIDONIC ACID; DIOXIN; ICOSANOID; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLINOSITOL; PHOSPHOLIPASE A2; PHOSPHOLIPASE A2 INHIBITOR; PHOSPHOLIPASE C; POLYCHLORINATED BIPHENYL; POLYCHLORINATED BIPHENYL DERIVATIVE; SYNAPTOPHYSIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ATTENTION; CELL LINE; CONTROLLED STUDY; DRUG EFFECT; ENZYME INHIBITION; EPITHELIUM CELL; LIVER; LIVER CELL; NONHUMAN; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; STEM CELL; TOXICITY;

ANIMALS; ARACHIDONIC ACID; CELL LINE; ENVIRONMENTAL POLLUTANTS; EPITHELIAL CELLS; LIVER; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHOLIPASES A2, CYTOSOLIC; POLYCHLORINATED BIPHENYLS; RATS; RATS, INBRED F344; SIGNAL TRANSDUCTION; STEM CELLS;

RATTUS;

EID: 41249101485     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2008.02.002     Document Type: Article

References (50)

1. Brant K.A., and Caruso R.L. PCB 50 stimulates release of arachidonic acid and prostaglandins from late gestation rat amnion fibroblast cells. Reprod. Toxicol. 22 (2006) 591-598
2. Brash A.R. Arachidonic acid as a bioactive molecule. J. Clin. Invest. 107 (2001) 1339-1345
3. Brekke O.L., Sagen E., and Bjerve K.S. Tumor necrosis factor-induced release of endogenous fatty acids analyzed by a highly sensitive high-performance liquid chromatography method. J. Lipid Res. 38 (1997) 1913-1922
4. Cao Y., Pearman A.T., Zimmerman G.A., McIntyre T.M., and Prescott S.M. Intracellular unesterified arachidonic acid signals apoptosis. Proc. Natl. Acad. Sci. U.S.A. 97 (2000) 11280-11285
5. 2- and arachidonic acid-mediated cytotoxicity. Free Radic. Biol. Med. 40 (2006) 364-375
6. Casado M., Callejas N.A., Rodrigo J., Zhao X., Dey S.K., Bosca L., and Martin-Sanz P. Contribution of cyclooxygenase 2 to liver regeneration after partial hepatectomy. FASEB J. 15 (2001) 2016-2018
7. 2 and MAP kinases in modulation of AA release and cell growth in A549 cells. Br. J. Pharmacol. 131 (2000) 255-265
8. Dumble M.L., Croager E.J., Yeoh G.C., and Quail E.A. Generation and characterization of p53 null transformed hepatic progenitor cells: oval cells give rise to hepatocellular carcinoma. Carcinogenesis 23 (2002) 435-445
9. 2 phosphorylation and translocation. BMC Biochem. 3 (2002) 30
10. 2-alpha. Biochem. Pharmacol. 71 (2005) 144-155
11. 2 regulation. J. Biol. Chem. 275 (2000) 20146-20156
12. Glauert H.P., Robertson L.W., and Silberhorn E.M. PCBs and tumor promotion. In: Robertson L.W., and Hansen L. (Eds). Recent Advances in the Environmental Toxicology and Health Effects of PCBs (2001), The University Press of Kentucky, Lexington, KY 355-371
13. 2 and arachidonic acid release in endothelial cells. Atherosclerosis 156 (2001) 81-90
14. Hansen L.G. Stepping backward to improve assessment of PCB congener toxicities. Environ. Health. Perspect. 106 Suppl. 1 (1998) 171-189
15. Hara A., and Radin N.S. Lipid extraction of tissues with a low-toxicity solvent. Anal. Biochem. 90 (1978) 420-426
16. 2 and PDGF in mesangial cells. Am. J. Physiol. Renal Physiol. 282 (2002) F485-F491
17. Hemming H., Flodström S., Fransson-Steen R., Wärngård L., and Ahlborg U.G. Inhibition of intercellular communication in cells in culture by polychlorinated biphenyls. Chemosphere 25 (1992) 939-945
18. Hii C.S., Ferrante A., Edwards Y.S., Huang Z.H., Hartfield P.J., Rathjen D.A., Poulos A., and Murray A.W. Activation of mitogen-activated protein kinase by arachidonic acid in rat liver epithelial WB cells by a protein kinase C-dependent mechanism. J. Biol. Chem. 270 (1995) 4201-4204
19. Hii C.S., Ferrante A., Schmidt S., Rathjen D.A., Robinson B.S., Poulos A., and Murray A.W. Inhibition of gap junctional communication by polyunsaturated fatty acids in WB cells: evidence that connexin 43 is not hyperphosphorylated. Carcinogenesis 16 (1995) 1505-1511
20. Hu K.Q. Cyclooxygenase 2 (COX2)-prostanoid pathway and liver diseases. Prostaglandins Leukot. Essent. Fatty Acids 69 (2003) 329-337
21. Knight B., Yeoh G.C., Husk K.L., Ly T., Abraham L.J., Yu C., Rhim J.A., and Fausto N. Impaired preneoplastic changes and liver tumor formation in tumor necrosis factor receptor type 1 knockout mice. J. Exp. Med. 192 (2000) 1809-1818
22. 3H]arachidonic acid release in rat cerebellar granule neurons. Toxicol. Sci. 68 (2002) 451-457
23. Krutovskikh V.A., Mesnil M., Mazzoleni G., and Yamasaki H. Inhibition of rat liver gap junction intercellular communication by tumor-promoting agents in vivo. Association with aberrant localization of connexin proteins. Lab. Invest. 72 (1995) 571-577
24. Larsson S.C., Kumlin M., Ingelman-Sundberg M., and Wolk A. Dietary long-chain n-3 fatty acids for the prevention of cancer: a review of potential mechanisms. Am. J. Clin. Nutr. 79 (2004) 935-945
25. Lee K.W., Kim M.S., Kang N.J., Kim D.H., Surh Y.J., Lee H.J., and Moon A. H-Ras selectively up-regulates MMP-9 and COX-2 through activation of ERK1/2 and NF-kappaB: an implication for invasive phenotype in rat liver epithelial cells. Int. J. Cancer 119 (2006) 1767-1775
26. Leng J., Han C., Demetris A.J., Michalopoulos G.K., and Wu T. Cyclooxygenase-2 promotes hepatocellular carcinoma cell growth through Akt activation: evidence for Akt inhibition in celecoxib-induced apoptosis. Hepatology 38 (2003) 756-768
27. Machala M., Bláha L., Lehmler H.J., Plíšková M., Májková Z., Kapplová P., Sovadinová I., Vondráček J., Malmberg T., and Robertson L.W. Toxicity of hydroxylated and quinoid PCB metabolites: inhibition of gap junctional intercellular communication and activation of aryl hydrocarbon and estrogen receptors in hepatic and mammary cells. Chem. Res. Toxicol. 17 (2004) 340-347
28. Machala M., Bláha L., Vondráček J., Trosko J.E., Scott J., and Upham B.L. Inhibition of gap junctional intercellular communication by noncoplanar polychlorinated biphenyls: inhibitory potencies and screening for potential mode(s) of action. Toxicol. Sci. 76 (2003) 102-111
29. Marks F., Muller-Decker K., and Furstenberger G. A causal relationship between unscheduled eicosanoid signalling and tumor development: cancer chemoprevention by inhibitors of arachidonic acid metabolism. Toxicology 153 (2000) 11-26
30. 2 activation by macrophage migration inhibitory factor (MIF). Regulatory role in cell proliferation and glucocorticoid action. J. Biol. Chem. 274 (1999) 18100-18106
31. Nimura N., Kinoshita T., Yoshida T., Uetake A., and Nakai C. 1-Pyrenyldiazomethane as a fluorescent labeling reagent for liquid-chromatographic determination of carboxylic-acids. Anal. Chem. 60 (1988) 2067-2070
32. 2 by the polychlorinated biphenyl mixture Aroclor 1242. Toxicol. Appl. Pharmacol. 163 (2000) 9-16
33. Pessah I.N., Hansen L.G., Albertson T.E., Garner C.E., Ta T.A., Do Z., Kim K.H., and Wong P.W. Structure-activity relationship for noncoplanar polychlorinated biphenyl congeners toward the ryanodine receptor-Ca2+ channel complex type 1 (RyR1). Chem. Res. Toxicol. 19 (2006) 92-101
34. Presnell S.C., Hooth M.J., Borchert K.M., Coleman W.B., Grisham J.W., and Smith G.J. Establishment of a functional HGF/C-MET autocrine loop in spontaneous transformants of WB-F344 rat liver stem-like cells. Hepatology 28 (1998) 1253-1259
35. Robertson L.W., and Hansen L. Recent Advances in the Environmental Toxicology and Health Effects of PCBs (2001), The University Press of Kentucky, Lexington, KY
36. Roskams T. Liver stem cells and their implication in hepatocellular and cholangiocarcinoma. Oncogene 25 (2006) 3818-3822
37. Rudnick D.A., Perlmutter D.H., and Muglia L.J. Prostaglandins are required for CREB activation and cellular proliferation during liver regeneration. Proc. Natl. Acad. Sci. U.S.A. 98 (2001) 8885-8890
38. Safe S.H. Polychlorinated biphenyls (PCBs): environmental impact, biochemical and toxic responses, and implications for risk assessment. Crit. Rev. Toxicol. 24 (1994) 87-149
39. Shafritz D.A., and Dabeva M.D. Liver stem cells and model systems for liver repopulation. J. Hepatol. 36 (2002) 552-564
40. Sirica A.E., Lai G.H., and Zhang Z. Biliary cancer growth factor pathways, cyclo-oxygenase-2 and potential therapeutic strategies. J. Gastroenterol. Hepatol. 16 (2001) 363-372
41. Swierenga S.H., Yamasaki H., Piccoli C., Robertson L., Bourgon L., Marceau N., and Fitzgerald D.J. Effects on intercellular communication in human keratinocytes and liver-derived cells of polychlorinated biphenyl congeners with differing in vivo promotion activities. Carcinogenesis 11 (1990) 921-926
42. Telliez A., Furman C., Pommery N., and Henichart J.P. Mechanisms leading to COX-2 expression and COX-2 induced tumorigenesis: topical therapeutic strategies targeting COX-2 expression and activity. Anticancer Agents Med. Chem. 6 (2006) 187-208
43. Tithof P.K., Elgayyar M., Cho Y., Guan W., Fisher A.B., and Peters-Golden M. Polycyclic aromatic hydrocarbons present in cigarette smoke cause endothelial cell apoptosis by a phospholipase A2-dependent mechanism. FASEB J. 16 (2002) 1463-1464
44. Tithof P.K., Peters-Golden M., and Ganey P.E. Distinct phospholipases A2 regulate the release of arachidonic acid for eicosanoid production and superoxide anion generation in neutrophils. J. Immunol. 160 (1998) 953-960
45. Umannová L., Zatloukalová J., Machala M., Krčmář P., Májková Z., Hennig B., Kozubik A., and Vondráček J. Tumor necrosis factor-alpha modulates effects of aryl hydrocarbon receptor ligands on cell proliferation and expression of cytochrome P450 enzymes in rat liver "stem-like" cells. Toxicol. Sci. 99 (2007) 79-89
46. Upham B.L., Bláha L., Babica P., Park J.-S., Sovadinová I., Pudrith C., Rummel A.M., Weis L.M., Sai K., Tithof P.K., Guzvic M., Vondráček J., Machala M., and Trosko J.E. Inhibition of intercellular signalling, a tumor promotion event, by a cigarette abundant PAH, depends on phosphatidylcholine-specific phospholipase C. Cancer. Sci. 99 (2008) 696-705
47. Upmacis R.K., Deeb R.S., Resnick M.J., Lindenbaum R., Gamss C., Mittar D., and Hajjar D.P. Involvement of the mitogen-activated protein kinase cascade in peroxynitrite-mediated arachidonic acid release in vascular smooth muscle cells. Am. J. Physiol. Cell. Physiol. 286 (2004) C1271-C1280
48. 2 and cyclooxygenase-2 in the proliferation of human cholangiocarcinoma cells. Hepatology 36 (2002) 363-373
49. 2. Free. Rad. Biol. Med. 34 (2003) 1531-1543
50. 2 signalling pathways in human hepatocellular carcinoma cells. Cancer Res. 66 (2006) 11859-11868