Inhibition of the MEK1/ERK pathway reduces arachidonic acid releaseindependently of cPLA2 phosphorylation and translocation

BMC Biochemistry

Volumn 3, Issue , 2002, Pages 1-12

  Evans, John H ^a   Fergus, Daniel J ^a   Leslie, Christina C ^a  

^a NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

Author keywords

Anisomycin; Arachidonic acid; Calcium; Cytosolic phospholipase A2; ERK; Fluorescent proteins; MEK; Phosphorylation; Translocation; UO126

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANISOMYCIN; ARACHIDONIC ACID; IONOMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; 1,3 BUTADIENE DERIVATIVE; 1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; CALCIUM; ENZYME INHIBITOR; GREEN FLUORESCENT PROTEIN; MAP2K1 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; NITRILE; PHOSPHOLIPASE A; PHOTOPROTEIN; PROTEIN SERINE THREONINE KINASE;

ARACHIDONIC ACID METABOLISM; ARTICLE; CALCIUM SIGNALING; CATALYSIS; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GOLGI COMPLEX; HUMAN; HUMAN CELL; WILD TYPE; ANIMAL; BINDING SITE; CELL LINE; CYTOSOL; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; FLUORESCENCE MICROSCOPY; GENETICS; METABOLISM; MUTATION; PHOSPHORYLATION; SECRETION; SIGNAL TRANSDUCTION; TRANSPORT AT THE CELLULAR LEVEL;

ADENOSINE TRIPHOSPHATE; ANIMALS; ARACHIDONIC ACID; BINDING SITES; BIOLOGICAL TRANSPORT; BUTADIENES; CALCIUM; CELL LINE; CYTOSOL; ENZYME INHIBITORS; GREEN FLUORESCENT PROTEINS; HUMANS; IONOMYCIN; LUMINESCENT PROTEINS; MAP KINASE KINASE 1; MAP KINASE SIGNALING SYSTEM; MICROSCOPY, FLUORESCENCE; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; MUTATION; NITRILES; PHOSPHOLIPASES A; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES;

EID: 18744383339     PISSN: 14712091     EISSN: None     Source Type: Journal    
DOI: 10.1186/1471-2091-3-30     Document Type: Article

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