-
1
-
-
22544461679
-
The role of the growth hormone/insulin-like growth factor axis in tumor growth and progression: lessons from animal models
-
Yakar S., Leroith D., and Brodt P. The role of the growth hormone/insulin-like growth factor axis in tumor growth and progression: lessons from animal models. Cytokine Growth Factor Rev 16 (2005) 407-420
-
(2005)
Cytokine Growth Factor Rev
, vol.16
, pp. 407-420
-
-
Yakar, S.1
Leroith, D.2
Brodt, P.3
-
3
-
-
17544374485
-
The role of the insulin-like growth factor system in colorectal cancer: review of current knowledge
-
Durai R., Yang W., Gupta S., et al. The role of the insulin-like growth factor system in colorectal cancer: review of current knowledge. Int J Colorectal Dis 20 (2005) 203-220
-
(2005)
Int J Colorectal Dis
, vol.20
, pp. 203-220
-
-
Durai, R.1
Yang, W.2
Gupta, S.3
-
4
-
-
0032924170
-
Differential autocrine regulation of intestine epithelial cell proliferation and differentiation by insulin-like growth factor (IGF) system components
-
Jehle P.M., Fussgaenger R.D., Blum W.F., et al. Differential autocrine regulation of intestine epithelial cell proliferation and differentiation by insulin-like growth factor (IGF) system components. Horm Metab Res 31 (1999) 97-102
-
(1999)
Horm Metab Res
, vol.31
, pp. 97-102
-
-
Jehle, P.M.1
Fussgaenger, R.D.2
Blum, W.F.3
-
5
-
-
0036173548
-
Circulating insulin-like growth factor-I levels regulate colon cancer growth and metastasis
-
Wu Y., Yakar S., Zhao L., et al. Circulating insulin-like growth factor-I levels regulate colon cancer growth and metastasis. Cancer Res 62 (2002) 1030-1035
-
(2002)
Cancer Res
, vol.62
, pp. 1030-1035
-
-
Wu, Y.1
Yakar, S.2
Zhao, L.3
-
6
-
-
0032170035
-
Regulation of vascular endothelial growth factor expression in human colon cancer by insulin-like growth factor-I
-
Akagi Y., Liu W., Zebrowski B., et al. Regulation of vascular endothelial growth factor expression in human colon cancer by insulin-like growth factor-I. Cancer Res 58 (1998) 4008-4014
-
(1998)
Cancer Res
, vol.58
, pp. 4008-4014
-
-
Akagi, Y.1
Liu, W.2
Zebrowski, B.3
-
7
-
-
0032836014
-
Integrins and E-cadherin cooperate with IGF-I to induce migration of epithelial colonic cells
-
Andre F., Rigot V., Thimonier J., et al. Integrins and E-cadherin cooperate with IGF-I to induce migration of epithelial colonic cells. Int J Cancer 83 (1999) 497-505
-
(1999)
Int J Cancer
, vol.83
, pp. 497-505
-
-
Andre, F.1
Rigot, V.2
Thimonier, J.3
-
8
-
-
0035988406
-
Prevention of cytokine-induced apoptosis by insulin-like growth factor-I is independent of cell adhesion molecules in HT29-D4 colon carcinoma cells-evidence for a NF-kappaB-dependent survival mechanism
-
Garrouste F., Remacle-Bonnet M., Fauriat C., et al. Prevention of cytokine-induced apoptosis by insulin-like growth factor-I is independent of cell adhesion molecules in HT29-D4 colon carcinoma cells-evidence for a NF-kappaB-dependent survival mechanism. Cell Death Differ 9 (2002) 768-779
-
(2002)
Cell Death Differ
, vol.9
, pp. 768-779
-
-
Garrouste, F.1
Remacle-Bonnet, M.2
Fauriat, C.3
-
9
-
-
0034676333
-
IGF-II/IGF-I receptor pathway up-regulates COX-2 mRNA expression and PGE2 synthesis in Caco-2 human colon carcinoma cells
-
Di Popolo A., Memoli A., Apicella A., et al. IGF-II/IGF-I receptor pathway up-regulates COX-2 mRNA expression and PGE2 synthesis in Caco-2 human colon carcinoma cells. Oncogene 19 (2000) 5517-5524
-
(2000)
Oncogene
, vol.19
, pp. 5517-5524
-
-
Di Popolo, A.1
Memoli, A.2
Apicella, A.3
-
10
-
-
0032885494
-
Expression of insulin-like growth factor-1 receptor in human colorectal cancer
-
Hakam A., Yeatman T.J., Lu L., et al. Expression of insulin-like growth factor-1 receptor in human colorectal cancer. Hum Pathol 30 (1999) 1128-1133
-
(1999)
Hum Pathol
, vol.30
, pp. 1128-1133
-
-
Hakam, A.1
Yeatman, T.J.2
Lu, L.3
-
11
-
-
0037110602
-
Overexpression of the insulin-like growth factor I receptor in human colon carcinomas
-
Weber M.M., Fottner C., Liu S.B., et al. Overexpression of the insulin-like growth factor I receptor in human colon carcinomas. Cancer 95 (2002) 2086-2095
-
(2002)
Cancer
, vol.95
, pp. 2086-2095
-
-
Weber, M.M.1
Fottner, C.2
Liu, S.B.3
-
12
-
-
19944425991
-
Low levels of insulin-like growth factor type 1 receptor expression at cancer cell membrane predict liver metastasis in Dukes' C human colorectal cancers
-
Nakamura M., Miyamoto S., Maeda H., et al. Low levels of insulin-like growth factor type 1 receptor expression at cancer cell membrane predict liver metastasis in Dukes' C human colorectal cancers. Clin Cancer Res 10 (2004) 8434-8441
-
(2004)
Clin Cancer Res
, vol.10
, pp. 8434-8441
-
-
Nakamura, M.1
Miyamoto, S.2
Maeda, H.3
-
13
-
-
0030962307
-
Gene expression profiles in normal and cancer cells
-
Zhang L., Zhou W., Velculescu V.E., et al. Gene expression profiles in normal and cancer cells. Science 276 (1997) 1268-1272
-
(1997)
Science
, vol.276
, pp. 1268-1272
-
-
Zhang, L.1
Zhou, W.2
Velculescu, V.E.3
-
14
-
-
9744231436
-
Interplay of insulin-like growth factor-II, insulin-like growth factor-I, insulin-like growth factor-I receptor, COX-2, and matrix metalloproteinase-7, play key roles in the early stage of colorectal carcinogenesis
-
Nosho K., Yamamoto H., Taniguchi H., et al. Interplay of insulin-like growth factor-II, insulin-like growth factor-I, insulin-like growth factor-I receptor, COX-2, and matrix metalloproteinase-7, play key roles in the early stage of colorectal carcinogenesis. Clin Cancer Res 10 (2004) 7950-7957
-
(2004)
Clin Cancer Res
, vol.10
, pp. 7950-7957
-
-
Nosho, K.1
Yamamoto, H.2
Taniguchi, H.3
-
15
-
-
11144356102
-
Loss of imprinting of insulin growth factor II gene: a potential heritable biomarker for colon neoplasia predisposition
-
Cruz-Correa M., Cui H., Giardiello F.M., et al. Loss of imprinting of insulin growth factor II gene: a potential heritable biomarker for colon neoplasia predisposition. Gastroenterology 126 (2004) 964-970
-
(2004)
Gastroenterology
, vol.126
, pp. 964-970
-
-
Cruz-Correa, M.1
Cui, H.2
Giardiello, F.M.3
-
16
-
-
0030872680
-
Acromegaly, colonic polyps and carcinoma
-
Jenkins P.J., Fairclough P.D., Richards T., et al. Acromegaly, colonic polyps and carcinoma. Clin Endocrinol (Oxf) 47 (1997) 17-22
-
(1997)
Clin Endocrinol (Oxf)
, vol.47
, pp. 17-22
-
-
Jenkins, P.J.1
Fairclough, P.D.2
Richards, T.3
-
17
-
-
0033678518
-
The prevalence and characteristics of colorectal neoplasia in acromegaly
-
Renehan A.G., Bhaskar P., Painter J.E., et al. The prevalence and characteristics of colorectal neoplasia in acromegaly. J Clin Endocrinol Metab 85 (2000) 3417-3424
-
(2000)
J Clin Endocrinol Metab
, vol.85
, pp. 3417-3424
-
-
Renehan, A.G.1
Bhaskar, P.2
Painter, J.E.3
-
18
-
-
0035987679
-
Acromegaly and cancer risk: a cohort study in Sweden and Denmark
-
Baris D., Gridley G., Ron E., et al. Acromegaly and cancer risk: a cohort study in Sweden and Denmark. Cancer Causes Control 13 (2002) 395-400
-
(2002)
Cancer Causes Control
, vol.13
, pp. 395-400
-
-
Baris, D.1
Gridley, G.2
Ron, E.3
-
19
-
-
0031759850
-
Mortality and cancer incidence in acromegaly: a retrospective cohort study. United Kingdom Acromegaly Study Group
-
Orme S.M., McNally R.J., Cartwright R.A., et al. Mortality and cancer incidence in acromegaly: a retrospective cohort study. United Kingdom Acromegaly Study Group. J Clin Endocrinol Metab 83 (1998) 2730-2734
-
(1998)
J Clin Endocrinol Metab
, vol.83
, pp. 2730-2734
-
-
Orme, S.M.1
McNally, R.J.2
Cartwright, R.A.3
-
20
-
-
0034614106
-
More about: prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3
-
Paterson A.C., Leeding K.S., Bach L.A., et al. More about: prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3. J Natl Cancer Inst 92 (2000) 1947-1950
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 1947-1950
-
-
Paterson, A.C.1
Leeding, K.S.2
Bach, L.A.3
-
21
-
-
0033531765
-
Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3
-
Ma J., Pollak M.N., Giovannucci E., et al. Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3. J Natl Cancer Inst 91 (1999) 620-625
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 620-625
-
-
Ma, J.1
Pollak, M.N.2
Giovannucci, E.3
-
22
-
-
0034605463
-
Serum C-peptide, insulin-like growth factor (IGF)-I, IGF-binding proteins, and colorectal cancer risk in women
-
Kaaks R., Toniolo P., Akhmedkhanov A., et al. Serum C-peptide, insulin-like growth factor (IGF)-I, IGF-binding proteins, and colorectal cancer risk in women. J Natl Cancer Inst 92 (2000) 1592-1600
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 1592-1600
-
-
Kaaks, R.1
Toniolo, P.2
Akhmedkhanov, A.3
-
24
-
-
0034019059
-
A prospective study of plasma insulin-like growth factor-1 and binding protein-3 and risk of colorectal neoplasia in women
-
Giovannucci E., Pollak M.N., Platz E.A., et al. A prospective study of plasma insulin-like growth factor-1 and binding protein-3 and risk of colorectal neoplasia in women. Cancer Epidemiol Biomarkers Prev 9 (2000) 345-349
-
(2000)
Cancer Epidemiol Biomarkers Prev
, vol.9
, pp. 345-349
-
-
Giovannucci, E.1
Pollak, M.N.2
Platz, E.A.3
-
25
-
-
0036112482
-
Plasma insulin-like growth factor 1, insulin-like growth factor binding protein 3, and risk of colorectal cancer: a prospective study in northern Sweden
-
Palmqvist R., Hallmans G., Rinaldi S., et al. Plasma insulin-like growth factor 1, insulin-like growth factor binding protein 3, and risk of colorectal cancer: a prospective study in northern Sweden. Gut 50 (2002) 642-646
-
(2002)
Gut
, vol.50
, pp. 642-646
-
-
Palmqvist, R.1
Hallmans, G.2
Rinaldi, S.3
-
26
-
-
0035977198
-
IGF-1. IGF-2 and IGFBP-3 in prediagnostic serum: association with colorectal cancer in a cohort of Chinese men in Shanghai
-
Probst-Hensch N.M., Yuan J.M., Stanczyk F.Z., et al. IGF-1. IGF-2 and IGFBP-3 in prediagnostic serum: association with colorectal cancer in a cohort of Chinese men in Shanghai. Br J Cancer 85 (2001) 1695-1699
-
(2001)
Br J Cancer
, vol.85
, pp. 1695-1699
-
-
Probst-Hensch, N.M.1
Yuan, J.M.2
Stanczyk, F.Z.3
-
27
-
-
0043011879
-
Serum insulin-like growth factor I and subsequent risk of colorectal cancer among Japanese-American men
-
Nomura A.M., Stemmermann G.N., Lee J., et al. Serum insulin-like growth factor I and subsequent risk of colorectal cancer among Japanese-American men. Am J Epidemiol 158 (2003) 424-431
-
(2003)
Am J Epidemiol
, vol.158
, pp. 424-431
-
-
Nomura, A.M.1
Stemmermann, G.N.2
Lee, J.3
-
28
-
-
33646241320
-
Physical activity, insulin-like growth factor 1, insulin-like growth factor binding protein 3, and survival from colorectal cancer
-
Haydon A.M., Macinnis R.J., English D.R., et al. Physical activity, insulin-like growth factor 1, insulin-like growth factor binding protein 3, and survival from colorectal cancer. Gut 55 (2006) 689-694
-
(2006)
Gut
, vol.55
, pp. 689-694
-
-
Haydon, A.M.1
Macinnis, R.J.2
English, D.R.3
-
29
-
-
1942436958
-
Insulin-like growth factor (IGF)-I, IGF binding protein-3, and cancer risk: systematic review and meta-regression analysis
-
Renehan A.G., Zwahlen M., Minder C., et al. Insulin-like growth factor (IGF)-I, IGF binding protein-3, and cancer risk: systematic review and meta-regression analysis. Lancet 363 (2004) 1346-1353
-
(2004)
Lancet
, vol.363
, pp. 1346-1353
-
-
Renehan, A.G.1
Zwahlen, M.2
Minder, C.3
-
30
-
-
23044493251
-
Blocking the insulin-like growth factor-I receptor as a strategy for targeting cancer
-
Hofmann F., and Garcia-Echeverria C. Blocking the insulin-like growth factor-I receptor as a strategy for targeting cancer. Drug Discov Today 10 (2005) 1041-1047
-
(2005)
Drug Discov Today
, vol.10
, pp. 1041-1047
-
-
Hofmann, F.1
Garcia-Echeverria, C.2
-
31
-
-
9144234724
-
A fully human monoclonal antibody to the insulin-like growth factor I receptor blocks ligand-dependent signaling and inhibits human tumor growth in vivo
-
Burtrum D., Zhu Z., Lu D., et al. A fully human monoclonal antibody to the insulin-like growth factor I receptor blocks ligand-dependent signaling and inhibits human tumor growth in vivo. Cancer Res 63 (2003) 8912-8921
-
(2003)
Cancer Res
, vol.63
, pp. 8912-8921
-
-
Burtrum, D.1
Zhu, Z.2
Lu, D.3
-
32
-
-
36148953021
-
Phase 1 dose escalation study of the anti-IGF-1R monoclonal antibody CP-751,871 in patients with refractory solid tumors
-
2007 ASCO annual meeting proceedings, Part I
-
Haluska P., Shaw H., Batzel G.N., et al. Phase 1 dose escalation study of the anti-IGF-1R monoclonal antibody CP-751,871 in patients with refractory solid tumors. 2007 ASCO annual meeting proceedings, Part I. J Clin Oncol 25 18S (2007) 3586
-
(2007)
J Clin Oncol
, vol.25
, Issue.18 S
, pp. 3586
-
-
Haluska, P.1
Shaw, H.2
Batzel, G.N.3
-
33
-
-
20144386856
-
Combination therapy enhances the inhibition of tumor growth with the fully human anti-type 1 insulin-like growth factor receptor monoclonal antibody CP-751,871
-
Cohen B.D., Baker D.A., Soderstrom C., et al. Combination therapy enhances the inhibition of tumor growth with the fully human anti-type 1 insulin-like growth factor receptor monoclonal antibody CP-751,871. Clin Cancer Res 11 (2005) 2063-2073
-
(2005)
Clin Cancer Res
, vol.11
, pp. 2063-2073
-
-
Cohen, B.D.1
Baker, D.A.2
Soderstrom, C.3
-
34
-
-
0042515293
-
An anti-insulin-like growth factor I receptor antibody that is a potent inhibitor of cancer cell proliferation
-
Maloney E.K., McLaughlin J.L., Dagdigian N.E., et al. An anti-insulin-like growth factor I receptor antibody that is a potent inhibitor of cancer cell proliferation. Cancer Res 63 (2003) 5073-5083
-
(2003)
Cancer Res
, vol.63
, pp. 5073-5083
-
-
Maloney, E.K.1
McLaughlin, J.L.2
Dagdigian, N.E.3
-
35
-
-
10344247119
-
A recombinant humanized anti-insulin-like growth factor receptor type I antibody (h7C10) enhances the antitumor activity of vinorelbine and anti-epidermal growth factor receptor therapy against human cancer xenografts
-
Goetsch L., Gonzalez A., Leger O., et al. A recombinant humanized anti-insulin-like growth factor receptor type I antibody (h7C10) enhances the antitumor activity of vinorelbine and anti-epidermal growth factor receptor therapy against human cancer xenografts. Int J Cancer 113 (2005) 316-328
-
(2005)
Int J Cancer
, vol.113
, pp. 316-328
-
-
Goetsch, L.1
Gonzalez, A.2
Leger, O.3
-
36
-
-
23844521596
-
Inhibition of insulin-like growth factor-I receptor (IGF-IR) signaling and tumor cell growth by a fully human neutralizing anti-IGF-IR antibody
-
Wang Y., Hailey J., Williams D., et al. Inhibition of insulin-like growth factor-I receptor (IGF-IR) signaling and tumor cell growth by a fully human neutralizing anti-IGF-IR antibody. Mol Cancer Ther 4 (2005) 1214-1221
-
(2005)
Mol Cancer Ther
, vol.4
, pp. 1214-1221
-
-
Wang, Y.1
Hailey, J.2
Williams, D.3
-
37
-
-
0037308651
-
A chimeric humanized single-chain antibody against the type I insulin-like growth factor (IGF) receptor renders breast cancer cells refractory to the mitogenic effects of IGF-I
-
Sachdev D., Li S.L., Hartell J.S., et al. A chimeric humanized single-chain antibody against the type I insulin-like growth factor (IGF) receptor renders breast cancer cells refractory to the mitogenic effects of IGF-I. Cancer Res 63 (2003) 627-635
-
(2003)
Cancer Res
, vol.63
, pp. 627-635
-
-
Sachdev, D.1
Li, S.L.2
Hartell, J.S.3
-
38
-
-
21244441508
-
A fully human recombinant IgG-like bispecific antibody to both the epidermal growth factor receptor and the insulin-like growth factor receptor for enhanced antitumor activity
-
Lu D., Zhang H., Koo H., et al. A fully human recombinant IgG-like bispecific antibody to both the epidermal growth factor receptor and the insulin-like growth factor receptor for enhanced antitumor activity. J Biol Chem 280 (2005) 19665-19672
-
(2005)
J Biol Chem
, vol.280
, pp. 19665-19672
-
-
Lu, D.1
Zhang, H.2
Koo, H.3
-
39
-
-
0033768157
-
Insulin-like growth factor I receptor antagonism augments response to chemoradiation therapy in colon cancer cells
-
Perer E.S., Madan A.K., Shurin A., et al. Insulin-like growth factor I receptor antagonism augments response to chemoradiation therapy in colon cancer cells. J Surg Res 94 (2000) 1-5
-
(2000)
J Surg Res
, vol.94
, pp. 1-5
-
-
Perer, E.S.1
Madan, A.K.2
Shurin, A.3
-
40
-
-
33751544431
-
Coexpression of the IGF-IR. EGFR and HER-2 is common in colorectal cancer patients
-
Cunningham M.P., Essapen S., Thomas H., et al. Coexpression of the IGF-IR. EGFR and HER-2 is common in colorectal cancer patients. Int J Oncol 28 (2006) 329-335
-
(2006)
Int J Oncol
, vol.28
, pp. 329-335
-
-
Cunningham, M.P.1
Essapen, S.2
Thomas, H.3
-
41
-
-
12144290914
-
Inhibition of the insulin-like growth factor receptor-1 tyrosine kinase activity as a therapeutic strategy for multiple myeloma, other hematologic malignancies, and solid tumors
-
Mitsiades C.S., Mitsiades N.S., McMullan C.J., et al. Inhibition of the insulin-like growth factor receptor-1 tyrosine kinase activity as a therapeutic strategy for multiple myeloma, other hematologic malignancies, and solid tumors. Cancer Cell 5 (2004) 221-230
-
(2004)
Cancer Cell
, vol.5
, pp. 221-230
-
-
Mitsiades, C.S.1
Mitsiades, N.S.2
McMullan, C.J.3
-
42
-
-
33750139113
-
Tyrosine kinase of insulin-like growth factor receptor as target for novel treatment and prevention strategies of colorectal cancer
-
Hopfner M., Sutter A.P., Huether A., et al. Tyrosine kinase of insulin-like growth factor receptor as target for novel treatment and prevention strategies of colorectal cancer. World J Gastroenterol 12 (2006) 5635-5643
-
(2006)
World J Gastroenterol
, vol.12
, pp. 5635-5643
-
-
Hopfner, M.1
Sutter, A.P.2
Huether, A.3
-
43
-
-
1642494838
-
Cyclolignans as inhibitors of the insulin-like growth factor-1 receptor and malignant cell growth
-
Girnita A., Girnita L., del Prete F., et al. Cyclolignans as inhibitors of the insulin-like growth factor-1 receptor and malignant cell growth. Cancer Res 64 (2004) 236-242
-
(2004)
Cancer Res
, vol.64
, pp. 236-242
-
-
Girnita, A.1
Girnita, L.2
del Prete, F.3
-
44
-
-
0142103667
-
Development of new insulin-like growth factor-1 receptor kinase inhibitors using catechol mimics
-
Blum G., Gazit A., and Levitzki A. Development of new insulin-like growth factor-1 receptor kinase inhibitors using catechol mimics. J Biol Chem 278 (2003) 40442-40454
-
(2003)
J Biol Chem
, vol.278
, pp. 40442-40454
-
-
Blum, G.1
Gazit, A.2
Levitzki, A.3
-
45
-
-
31544464616
-
In vitro and in vivo antitumor effects of the dual insulin-like growth factor-I/insulin receptor inhibitor, BMS-554417
-
Haluska P., Carboni J.M., Loegering D.A., et al. In vitro and in vivo antitumor effects of the dual insulin-like growth factor-I/insulin receptor inhibitor, BMS-554417. Cancer Res 66 (2006) 362-371
-
(2006)
Cancer Res
, vol.66
, pp. 362-371
-
-
Haluska, P.1
Carboni, J.M.2
Loegering, D.A.3
-
46
-
-
20944440088
-
Tumor development by transgenic expression of a constitutively active insulin-like growth factor I receptor
-
Carboni J.M., Lee A.V., Hadsell D.L., et al. Tumor development by transgenic expression of a constitutively active insulin-like growth factor I receptor. Cancer Res 65 (2005) 3781-3787
-
(2005)
Cancer Res
, vol.65
, pp. 3781-3787
-
-
Carboni, J.M.1
Lee, A.V.2
Hadsell, D.L.3
-
47
-
-
41249093749
-
A novel, potent and selective IGF-1R small molecule inhibitor blocks activation of IGF-1R signaling in vitro and inhibits IGF-1R dependent tumor growth in vivo
-
LB-281
-
Ji Q.-S., Mulvihill M., Franklin M., et al. A novel, potent and selective IGF-1R small molecule inhibitor blocks activation of IGF-1R signaling in vitro and inhibits IGF-1R dependent tumor growth in vivo. Proc Am Assoc Cancer Res 47 (2006) LB-281
-
(2006)
Proc Am Assoc Cancer Res
, vol.47
-
-
Ji, Q.-S.1
Mulvihill, M.2
Franklin, M.3
-
48
-
-
0030274748
-
Regression of C6 rat brain tumors by cells expressing an antisense insulin-like growth factor I receptor RNA
-
Resnicoff M., Tjuvajev J., Rotman H.L., et al. Regression of C6 rat brain tumors by cells expressing an antisense insulin-like growth factor I receptor RNA. J Exp Ther Oncol 1 (1996) 385-389
-
(1996)
J Exp Ther Oncol
, vol.1
, pp. 385-389
-
-
Resnicoff, M.1
Tjuvajev, J.2
Rotman, H.L.3
-
49
-
-
0035871490
-
Results of a pilot study involving the use of an antisense oligodeoxynucleotide directed against the insulin-like growth factor type I receptor in malignant astrocytomas
-
Andrews D.W., Resnicoff M., Flanders A.E., et al. Results of a pilot study involving the use of an antisense oligodeoxynucleotide directed against the insulin-like growth factor type I receptor in malignant astrocytomas. J Clin Oncol 19 (2001) 2189-2200
-
(2001)
J Clin Oncol
, vol.19
, pp. 2189-2200
-
-
Andrews, D.W.1
Resnicoff, M.2
Flanders, A.E.3
-
50
-
-
0031785253
-
Inhibition of tumor growth by a dominant negative mutant of the insulin-like growth factor I receptor with a bystander effect
-
Reiss K., D'Ambrosio C., Tu X., et al. Inhibition of tumor growth by a dominant negative mutant of the insulin-like growth factor I receptor with a bystander effect. Clin Cancer Res 4 (1998) 2647-2655
-
(1998)
Clin Cancer Res
, vol.4
, pp. 2647-2655
-
-
Reiss, K.1
D'Ambrosio, C.2
Tu, X.3
-
51
-
-
77954802903
-
Insulin-like growth factor-binding protein 3: single-agent and synergistic effects with chemotherapeutic drugs on solid tumour models
-
Yu Q., Banerjee K., Paterson J., et al. Insulin-like growth factor-binding protein 3: single-agent and synergistic effects with chemotherapeutic drugs on solid tumour models. Proc Am Assoc Cancer Res (2003)
-
(2003)
Proc Am Assoc Cancer Res
-
-
Yu, Q.1
Banerjee, K.2
Paterson, J.3
-
52
-
-
0030872966
-
Polyethylene glycol conjugated insulin-like growth factor binding protein-1 (IGFBP-1) inhibits growth of breast cancer in athymic mice
-
Van den Berg C.L., Cox G.N., Stroh C.A., et al. Polyethylene glycol conjugated insulin-like growth factor binding protein-1 (IGFBP-1) inhibits growth of breast cancer in athymic mice. Eur J Cancer 33 (1997) 1108-1113
-
(1997)
Eur J Cancer
, vol.33
, pp. 1108-1113
-
-
Van den Berg, C.L.1
Cox, G.N.2
Stroh, C.A.3
-
53
-
-
0027366338
-
Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type 1 insulin-like growth factor receptor
-
Sell C., Rubini M., Rubin R., et al. Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type 1 insulin-like growth factor receptor. Proc Natl Acad Sci USA 90 (1993) 11217-11221
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 11217-11221
-
-
Sell, C.1
Rubini, M.2
Rubin, R.3
-
54
-
-
0028890744
-
The insulin-like growth factor I receptor: a key to tumor growth?
-
Baserga R. The insulin-like growth factor I receptor: a key to tumor growth?. Cancer Res 55 (1995) 249-252
-
(1995)
Cancer Res
, vol.55
, pp. 249-252
-
-
Baserga, R.1
-
55
-
-
36348954086
-
Efficacy of the anti-insulin like growth factor 1 receptor (IGF-1R) antibody CP-751871 in combination with paclitaxel and carboplatin as first-line treatment for advanced non-small cell lung cancer (NSCLC)
-
2007 ASCO annual meeting proceedings, Part I
-
Karp D.D., Paz-Ares L.G., Blakely L.J., et al. Efficacy of the anti-insulin like growth factor 1 receptor (IGF-1R) antibody CP-751871 in combination with paclitaxel and carboplatin as first-line treatment for advanced non-small cell lung cancer (NSCLC). 2007 ASCO annual meeting proceedings, Part I. J Clin Oncol 25 18S (2007) 7506
-
(2007)
J Clin Oncol
, vol.25
, Issue.18 S
, pp. 7506
-
-
Karp, D.D.1
Paz-Ares, L.G.2
Blakely, L.J.3
-
56
-
-
36148976199
-
A phase 1 pharmacokinetic and pharmacodynamic study of AMG 479, a fully human monoclonal antibody against insulin-like growth factor type 1 receptor (IGF-1R), in advanced solid tumors
-
2007 ASCO annual meeting proceedings, Part I
-
Tolcher A.W., Rothenberg M.L., Rodon J., et al. A phase 1 pharmacokinetic and pharmacodynamic study of AMG 479, a fully human monoclonal antibody against insulin-like growth factor type 1 receptor (IGF-1R), in advanced solid tumors. 2007 ASCO annual meeting proceedings, Part I. J Clin Oncol 25 18S (2007) 3002
-
(2007)
J Clin Oncol
, vol.25
, Issue.18 S
, pp. 3002
-
-
Tolcher, A.W.1
Rothenberg, M.L.2
Rodon, J.3
-
57
-
-
36148981957
-
A phase 1 study of q3W R1507, a human monoclonal antibody IGF-1R antagonist in patients with advanced cancer
-
2007 ASCO annual meeting proceedings, Part I
-
Rodon J., Patnaik A., Stein M., et al. A phase 1 study of q3W R1507, a human monoclonal antibody IGF-1R antagonist in patients with advanced cancer. 2007 ASCO annual meeting proceedings, Part I. J Clin Oncol 25 18S (2007) 3590
-
(2007)
J Clin Oncol
, vol.25
, Issue.18 S
, pp. 3590
-
-
Rodon, J.1
Patnaik, A.2
Stein, M.3
|