Sulfonamidolactam inhibitors of coagulation factor Xa

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 7, 2008, Pages 2428-2433

  Smallheer, Joanne M ^a   Wang, Shuaige ^a   Laws, Mia L ^a   Nakajima, Suanne ^a   Hu, Zilun ^a   Han, Wei ^a   Jacobson, Irina ^a   Luettgen, Joseph M ^a   Rossi, Karen A ^a   Rendina, Alan R ^a   Knabb, Robert M ^a   Wexler, Ruth R ^a   Lam, Patrick Y S ^a   Quan, Mimi L ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

Anticoagulant; Antithrombotic; Factor Xa inhibitors; Serine protease inhibitors

Indexed keywords

BLOOD CLOTTING FACTOR 10A INHIBITOR; LACTAM DERIVATIVE; NITROGEN; SULFONAMIDE;

ARTICLE; DRUG POTENCY; DRUG STRUCTURE; SUBSTITUTION REACTION;

ANTICOAGULANTS; BINDING SITES; BLOOD COAGULATION TESTS; FACTOR XA; LACTAMS; LIGANDS; MODELS, CHEMICAL; PIPERIDONES; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES;

EID: 41149130901     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.02.054     Document Type: Article

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