메뉴 건너뛰기




Volumn 35, Issue SUPPL. 1, 2008, Pages

In vivo calcium imaging of the aging and diseased brain

Author keywords

Alzheimer's disease; In vivo calcium imaging; Lipofuscin; Plaques

Indexed keywords

2 (4' METHYLAMINOPHENYL) 6 HYDROXYBENZOTHIAZOLE C 11; CALCIUM; DIRECT YELLOW 7; FLUORESCENT DYE; LIPOFUSCIN; SULFORHODAMINE 101; THIOFLAVINE; UNCLASSIFIED DRUG;

EID: 41149119937     PISSN: 16197070     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00259-007-0709-6     Document Type: Review
Times cited : (51)

References (56)
  • 2
    • 34248997850 scopus 로고    scopus 로고
    • The importance of being subtle: Small changes in calcium homeostasis control cognitive decline in normal aging
    • Toescu EC, Verkhratsky A. The importance of being subtle: small changes in calcium homeostasis control cognitive decline in normal aging. Aging Cell. 2007;6:267-73.
    • (2007) Aging Cell. , vol.6 , pp. 267-273
    • Toescu, E.C.1    Verkhratsky, A.2
  • 3
    • 33947493213 scopus 로고    scopus 로고
    • Expansion of the calcium hypothesis of brain aging and Alzheimer's disease: Minding the store
    • Thibault O, Gant JC, Landfield PW. Expansion of the calcium hypothesis of brain aging and Alzheimer's disease: minding the store. Aging Cell. 2007;6:307-17.
    • (2007) Aging Cell. , vol.6 , pp. 307-317
    • Thibault, O.1    Gant, J.C.2    Landfield, P.W.3
  • 4
    • 34249030943 scopus 로고    scopus 로고
    • Calcium buffering systems and calcium signaling in aged rat basal forebrain neurons
    • Murchison D, Griffith WH. Calcium buffering systems and calcium signaling in aged rat basal forebrain neurons. Aging Cell. 2007;6:297-305.
    • (2007) Aging Cell. , vol.6 , pp. 297-305
    • Murchison, D.1    Griffith, W.H.2
  • 5
    • 0026787530 scopus 로고
    • Measurements of intracellular calcium in sensory neurons of adult and old rats
    • Kirischuk S, Pronchuk N, Verkhratsky A. Measurements of intracellular calcium in sensory neurons of adult and old rats. Neuroscience. 1992;50:947-51.
    • (1992) Neuroscience. , vol.50 , pp. 947-951
    • Kirischuk, S.1    Pronchuk, N.2    Verkhratsky, A.3
  • 6
    • 0030567769 scopus 로고    scopus 로고
    • Calcium homeostasis in aged neurons
    • Kirischuk S, Verkhratsky A. Calcium homeostasis in aged neurons. Life Sci. 1996;59:451-9.
    • (1996) Life Sci. , vol.59 , pp. 451-459
    • Kirischuk, S.1    Verkhratsky, A.2
  • 7
    • 0031816168 scopus 로고    scopus 로고
    • Increased calcium buffering in basal forebrain neurons during aging
    • Murchison D, Griffith WH. Increased calcium buffering in basal forebrain neurons during aging. J Neurophysiol. 1998;80:350-64.
    • (1998) J Neurophysiol. , vol.80 , pp. 350-364
    • Murchison, D.1    Griffith, W.H.2
  • 8
    • 0037115050 scopus 로고    scopus 로고
    • 2+ homeostasis in aged cerebellar granule neurons in brain slices
    • 2+ homeostasis in aged cerebellar granule neurons in brain slices. J Neurosci. 2002;22:10761-71.
    • (2002) J Neurosci. , vol.22 , pp. 10761-10771
    • Xiong, J.1    Verkhratsky, A.2    Toescu, E.C.3
  • 10
    • 0029782113 scopus 로고    scopus 로고
    • Increase in single L-type calcium channels in hippocampal neurons during aging
    • Thibault O, Landfield PW. Increase in single L-type calcium channels in hippocampal neurons during aging. Science. 1996;272:1017-20.
    • (1996) Science. , vol.272 , pp. 1017-1020
    • Thibault, O.1    Landfield, P.W.2
  • 11
    • 0029896492 scopus 로고    scopus 로고
    • High-voltage-activated calcium currents in basal forebrain neurons during aging
    • Murchison D, Griffith WH. High-voltage-activated calcium currents in basal forebrain neurons during aging. J Neurophysiol. 1996;76:158-74.
    • (1996) J Neurophysiol. , vol.76 , pp. 158-174
    • Murchison, D.1    Griffith, W.H.2
  • 12
    • 0031451847 scopus 로고    scopus 로고
    • 2+-dependent processes: Relation to hippocampal synaptic plasticity
    • 2+-dependent processes: relation to hippocampal synaptic plasticity. Hippocampus. 1997;7:602-12.
    • (1997) Hippocampus. , vol.7 , pp. 602-612
    • Foster, T.C.1    Norris, C.M.2
  • 13
    • 0036830947 scopus 로고    scopus 로고
    • Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease
    • LaFerla FM. Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease. Nat Rev Neurosci. 2002;3:862-72.
    • (2002) Nat Rev Neurosci. , vol.3 , pp. 862-872
    • Laferla, F.M.1
  • 15
    • 0037289779 scopus 로고    scopus 로고
    • Ca2+ signaling in mouse cortical neurons studied by two-photon imaging and photoreleased inositol triphosphate
    • Stutzmann GE, LaFerla FM, Parker I. Ca2+ signaling in mouse cortical neurons studied by two-photon imaging and photoreleased inositol triphosphate. J Neurosci. 2003;23:758-65.
    • (2003) J Neurosci. , vol.23 , pp. 758-765
    • Stutzmann, G.E.1    Laferla, F.M.2    Parker, I.3
  • 17
    • 34247621471 scopus 로고    scopus 로고
    • Enhanced ryanodine-mediated calcium release in mutant PS1-expressing Alzheimer's mouse models
    • Stutzmann GE, Smith I, Caccamo A, Oddo S, Parker I, Laferla FM. Enhanced ryanodine-mediated calcium release in mutant PS1-expressing Alzheimer's mouse models. Ann N Y Acad Sci. 2007;1097:265-77.
    • (2007) Ann N Y Acad Sci. , vol.1097 , pp. 265-277
    • Stutzmann, G.E.1    Smith, I.2    Caccamo, A.3    Oddo, S.4    Parker, I.5    Laferla, F.M.6
  • 19
    • 0025342635 scopus 로고
    • Two-photon laser scanning fluorescence microscopy
    • Denk W, Strickler JH, Webb WW. Two-photon laser scanning fluorescence microscopy. Science. 1990;248:73-6.
    • (1990) Science. , vol.248 , pp. 73-76
    • Denk, W.1    Strickler, J.H.2    Webb, W.W.3
  • 20
    • 0031021713 scopus 로고    scopus 로고
    • In vivo dendritic calcium dynamics in neocortical pyramidal neurons
    • Svoboda K, Denk W, Kleinfeld D, Tank DW. In vivo dendritic calcium dynamics in neocortical pyramidal neurons. Nature. 1997;385:161-5.
    • (1997) Nature. , vol.385 , pp. 161-165
    • Svoboda, K.1    Denk, W.2    Kleinfeld, D.3    Tank, D.W.4
  • 21
    • 30944450665 scopus 로고    scopus 로고
    • Deep tissue two-photon microscopy
    • Helmchen F, Denk W. Deep tissue two-photon microscopy. Nat Methods. 2005;2:932-40.
    • (2005) Nat Methods. , vol.2 , pp. 932-940
    • Helmchen, F.1    Denk, W.2
  • 22
    • 0035923747 scopus 로고    scopus 로고
    • Representation of odorants by receptor neuron input to the mouse olfactory bulb
    • Wachowiak M, Cohen LB. Representation of odorants by receptor neuron input to the mouse olfactory bulb. Neuron. 2001;32:723-35.
    • (2001) Neuron. , vol.32 , pp. 723-735
    • Wachowiak, M.1    Cohen, L.B.2
  • 24
    • 33751113978 scopus 로고    scopus 로고
    • Targeted bulk-loading of fluorescent indicators for two-photon brain imaging in vivo
    • Garaschuk O, Milos RI, Konnerth A. Targeted bulk-loading of fluorescent indicators for two-photon brain imaging in vivo. Nat Prot. 2006;1:380-6.
    • (2006) Nat Prot. , vol.1 , pp. 380-386
    • Garaschuk, O.1    Milos, R.I.2    Konnerth, A.3
  • 27
    • 34547952060 scopus 로고    scopus 로고
    • Troponin C-based biosensors: A new family of genetically encoded indicators for in vivo calcium imaging in the nervous system
    • Garaschuk O, Griesbeck O, Konnerth A. Troponin C-based biosensors: a new family of genetically encoded indicators for in vivo calcium imaging in the nervous system. Cell Calcium. 2007;42:351-61.
    • (2007) Cell Calcium. , vol.42 , pp. 351-361
    • Garaschuk, O.1    Griesbeck, O.2    Konnerth, A.3
  • 28
    • 33947187417 scopus 로고    scopus 로고
    • In vivo calcium imaging from genetically specified target cells in mouse cerebellum
    • Diez-Garcia J, Akemann W, Knopfel T. In vivo calcium imaging from genetically specified target cells in mouse cerebellum. Neuroimage. 2007;34:859-69.
    • (2007) Neuroimage. , vol.34 , pp. 859-869
    • Diez-Garcia, J.1    Akemann, W.2    Knopfel, T.3
  • 32
    • 5344277556 scopus 로고    scopus 로고
    • Deciphering the molecular basis of memory failure in Alzheimer's disease
    • Walsh DM, Selkoe DJ. Deciphering the molecular basis of memory failure in Alzheimer's disease. Neuron. 2004;44:181-93.
    • (2004) Neuron. , vol.44 , pp. 181-193
    • Walsh, D.M.1    Selkoe, D.J.2
  • 33
    • 0036548070 scopus 로고    scopus 로고
    • Gamma-secretase, notch, Abeta and Alzheimer's disease: Where do the presenilins fit in
    • Sisodia SS, St George-Hyslop PH. Gamma-secretase, notch, Abeta and Alzheimer's disease: where do the presenilins fit in. Nat Rev Neurosci. 2002;3:281-90.
    • (2002) Nat Rev Neurosci. , vol.3 , pp. 281-290
    • Sisodia, S.S.1    St George-Hyslop, P.H.2
  • 34
    • 33847662852 scopus 로고    scopus 로고
    • Soluble protein oligomers in neurodegeneration: Lessons from the Alzheimer's amyloid beta-peptide
    • Haass C, Selkoe DJ. Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide. Nat Rev Mol Cell Biol. 2007;8:101-12.
    • (2007) Nat Rev Mol Cell Biol. , vol.8 , pp. 101-112
    • Haass, C.1    Selkoe, D.J.2
  • 35
    • 0028985574 scopus 로고
    • Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein
    • Games D, Adams D, Alessandrini R, Barbour R, Berthelette P, Blackwell C, et al. Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein. Nature. 1995;373:523-7.
    • (1995) Nature. , vol.373 , pp. 523-527
    • Games, D.1    Adams, D.2    Alessandrini, R.3    Barbour, R.4    Berthelette, P.5    Blackwell, C.6
  • 36
    • 0029742199 scopus 로고    scopus 로고
    • Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice
    • Hsiao K, Chapman P, Nilsen S, Eckman C, Harigaya Y, Younkin S, et al. Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice. Science. 1996;274:99-102.
    • (1996) Science. , vol.274 , pp. 99-102
    • Hsiao, K.1    Chapman, P.2    Nilsen, S.3    Eckman, C.4    Harigaya, Y.5    Younkin, S.6
  • 38
    • 0042697305 scopus 로고    scopus 로고
    • Triple-transgenic model of Alzheimer's disease with plaques and tangles: Intracellular Abeta and synaptic dysfunction
    • Oddo S, Caccamo A, Shepherd JD, Murphy MP, Golde TE, Kayed R, et al. Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction. Neuron. 2003;39:409-21.
    • (2003) Neuron. , vol.39 , pp. 409-421
    • Oddo, S.1    Caccamo, A.2    Shepherd, J.D.3    Murphy, M.P.4    Golde, T.E.5    Kayed, R.6
  • 39
    • 33748988258 scopus 로고    scopus 로고
    • Abeta42-driven cerebral amyloidosis in transgenic mice reveals early and robust pathology
    • Radde R, Bolmont T, Kaeser SA, Coomaraswamy J, Lindau D, Stoltze L, et al. Abeta42-driven cerebral amyloidosis in transgenic mice reveals early and robust pathology. EMBO Rep. 2006;7:940-6.
    • (2006) EMBO Rep. , vol.7 , pp. 940-946
    • Radde, R.1    Bolmont, T.2    Kaeser, S.A.3    Coomaraswamy, J.4    Lindau, D.5    Stoltze, L.6
  • 40
    • 0035116442 scopus 로고    scopus 로고
    • Growth arrest of individual senile plaques in a model of Alzheimer's disease observed by in vivo multiphoton microscopy
    • Christie RH, Bacskai BJ, Zipfel WR, Williams RM, Kajdasz ST, Webb WW, et al. Growth arrest of individual senile plaques in a model of Alzheimer's disease observed by in vivo multiphoton microscopy. J Neurosci. 2001;21:858-64.
    • (2001) J Neurosci. , vol.21 , pp. 858-864
    • Christie, R.H.1    Bacskai, B.J.2    Zipfel, W.R.3    Williams, R.M.4    Kajdasz, S.T.5    Webb, W.W.6
  • 41
    • 0142123057 scopus 로고    scopus 로고
    • Four-dimensional multiphoton imaging of brain entry, amyloid binding, and clearance of an amyloid-beta ligand in transgenic mice
    • Bacskai BJ, Hickey GA, Skoch J, Kajdasz ST, Wang Y, Huang GF, et al. Four-dimensional multiphoton imaging of brain entry, amyloid binding, and clearance of an amyloid-beta ligand in transgenic mice. Proc Natl Acad Sci U S A. 2003;100:12462-7.
    • (2003) Proc Natl Acad Sci U S A. , vol.100 , pp. 12462-12467
    • Bacskai, B.J.1    Hickey, G.A.2    Skoch, J.3    Kajdasz, S.T.4    Wang, Y.5    Huang, G.F.6
  • 42
    • 0037444553 scopus 로고    scopus 로고
    • In vivo imaging of reactive oxygen species specifically associated with thioflavine S-positive amyloid plaques by multiphoton microscopy
    • McLellan ME, Kajdasz ST, Hyman BT, Bacskai BJ. In vivo imaging of reactive oxygen species specifically associated with thioflavine S-positive amyloid plaques by multiphoton microscopy. J Neurosci. 2003;23:2212-7.
    • (2003) J Neurosci. , vol.23 , pp. 2212-2217
    • McLellan, M.E.1    Kajdasz, S.T.2    Hyman, B.T.3    Bacskai, B.J.4
  • 43
    • 0036707494 scopus 로고    scopus 로고
    • Imaging Abeta plaques in living transgenic mice with multiphoton microscopy and methoxy-X04, a systemically administered Congo red derivative
    • Klunk WE, Bacskai BJ, Mathis CA, Kajdasz ST, McLellan ME, Frosch MP, et al. Imaging Abeta plaques in living transgenic mice with multiphoton microscopy and methoxy-X04, a systemically administered Congo red derivative. J Neuropathol Exp Neurol. 2002;61:797-805.
    • (2002) J Neuropathol Exp Neurol. , vol.61 , pp. 797-805
    • Klunk, W.E.1    Bacskai, B.J.2    Mathis, C.A.3    Kajdasz, S.T.4    McLellan, M.E.5    Frosch, M.P.6
  • 44
    • 0035106780 scopus 로고    scopus 로고
    • Imaging of amyloid-beta deposits in brains of living mice permits direct observation of clearance of plaques with immunotherapy
    • Bacskai BJ, Kajdasz ST, Christie RH, Carter C, Games D, Seubert P, et al. Imaging of amyloid-beta deposits in brains of living mice permits direct observation of clearance of plaques with immunotherapy. Nat Med. 2001;7:369-72.
    • (2001) Nat Med. , vol.7 , pp. 369-372
    • Bacskai, B.J.1    Kajdasz, S.T.2    Christie, R.H.3    Carter, C.4    Games, D.5    Seubert, P.6
  • 46
    • 18744409106 scopus 로고    scopus 로고
    • Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo
    • Nimmerjahn A, Kirchhoff F, Kerr JN, Helmchen F. Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo. Nat Methods. 2004;1:31-7.
    • (2004) Nat Methods. , vol.1 , pp. 31-37
    • Nimmerjahn, A.1    Kirchhoff, F.2    Kerr, J.N.3    Helmchen, F.4
  • 47
    • 0034028817 scopus 로고    scopus 로고
    • Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion
    • Jung S, Aliberti J, Graemmel P, Sunshine MJ, Kreutzberg GW, Sher A, et al. Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion. Mol Cell Biol. 2000;20:4106-14.
    • (2000) Mol Cell Biol. , vol.20 , pp. 4106-4114
    • Jung, S.1    Aliberti, J.2    Graemmel, P.3    Sunshine, M.J.4    Kreutzberg, G.W.5    Sher, A.6
  • 48
    • 25444469608 scopus 로고    scopus 로고
    • Visualization of microglia in living tissues using Iba1-EGFP transgenic mice
    • Hirasawa T, Ohsawa K, Imai Y, Ondo Y, Akazawa C, Uchino S, et al. Visualization of microglia in living tissues using Iba1-EGFP transgenic mice. J Neurosci Res. 2005;81:357-62.
    • (2005) J Neurosci Res. , vol.81 , pp. 357-362
    • Hirasawa, T.1    Ohsawa, K.2    Imai, Y.3    Ondo, Y.4    Akazawa, C.5    Uchino, S.6
  • 49
    • 0018763698 scopus 로고
    • Autofluorescence of viable cultured mammalian cells
    • Aubin JE. Autofluorescence of viable cultured mammalian cells. J Histochem Cytochem. 1979;27:36-43.
    • (1979) J Histochem Cytochem. , vol.27 , pp. 36-43
    • Aubin, J.E.1
  • 50
    • 0036241090 scopus 로고    scopus 로고
    • Pigments in aging: An overview
    • Porta EA. Pigments in aging: an overview. Ann N Y Acad Sci. 2002;959:57-65.
    • (2002) Ann N Y Acad Sci. , vol.959 , pp. 57-65
    • Porta, E.A.1
  • 52
    • 0036710928 scopus 로고    scopus 로고
    • Lipofuscin: Mechanisms of age-related accumulation and influence on cell function
    • Brunk UT, Terman A. Lipofuscin: mechanisms of age-related accumulation and influence on cell function. Free Radic Biol Med. 2002;33:611-9.
    • (2002) Free Radic Biol Med. , vol.33 , pp. 611-619
    • Brunk, U.T.1    Terman, A.2
  • 53
    • 33744475390 scopus 로고    scopus 로고
    • Two-photon excited autofluorescence imaging of human retinal pigment epithelial cells
    • Han M, Bindewald-Wittich A, Holz FG, Giese G, Niemz MH, Snyder S, et al. Two-photon excited autofluorescence imaging of human retinal pigment epithelial cells. J Biomed Opt. 2006;11:0105011-3.
    • (2006) J Biomed Opt. , vol.11 , pp. 0105011-0105013
    • Han, M.1    Bindewald-Wittich, A.2    Holz, F.G.3    Giese, G.4    Niemz, M.H.5    Snyder, S.6
  • 55
    • 0002018965 scopus 로고    scopus 로고
    • Two-photon cross sections of indicators
    • Cold Spring Harbor Press Cold Spring Harbor
    • Xu C. Two-photon cross sections of indicators. In: Yuste R, Konnerth A, editors. Imaging: a laboratory manual. Cold Spring Harbor: Cold Spring Harbor Press; 2000. pp 19.1-19.9.
    • (2000) Imaging: A Laboratory Manual , pp. 191-199
    • Xu, C.1    Yuste, R.2    Konnerth, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.