-
2
-
-
34248997850
-
The importance of being subtle: Small changes in calcium homeostasis control cognitive decline in normal aging
-
Toescu EC, Verkhratsky A. The importance of being subtle: small changes in calcium homeostasis control cognitive decline in normal aging. Aging Cell. 2007;6:267-73.
-
(2007)
Aging Cell.
, vol.6
, pp. 267-273
-
-
Toescu, E.C.1
Verkhratsky, A.2
-
3
-
-
33947493213
-
Expansion of the calcium hypothesis of brain aging and Alzheimer's disease: Minding the store
-
Thibault O, Gant JC, Landfield PW. Expansion of the calcium hypothesis of brain aging and Alzheimer's disease: minding the store. Aging Cell. 2007;6:307-17.
-
(2007)
Aging Cell.
, vol.6
, pp. 307-317
-
-
Thibault, O.1
Gant, J.C.2
Landfield, P.W.3
-
4
-
-
34249030943
-
Calcium buffering systems and calcium signaling in aged rat basal forebrain neurons
-
Murchison D, Griffith WH. Calcium buffering systems and calcium signaling in aged rat basal forebrain neurons. Aging Cell. 2007;6:297-305.
-
(2007)
Aging Cell.
, vol.6
, pp. 297-305
-
-
Murchison, D.1
Griffith, W.H.2
-
5
-
-
0026787530
-
Measurements of intracellular calcium in sensory neurons of adult and old rats
-
Kirischuk S, Pronchuk N, Verkhratsky A. Measurements of intracellular calcium in sensory neurons of adult and old rats. Neuroscience. 1992;50:947-51.
-
(1992)
Neuroscience.
, vol.50
, pp. 947-951
-
-
Kirischuk, S.1
Pronchuk, N.2
Verkhratsky, A.3
-
6
-
-
0030567769
-
Calcium homeostasis in aged neurons
-
Kirischuk S, Verkhratsky A. Calcium homeostasis in aged neurons. Life Sci. 1996;59:451-9.
-
(1996)
Life Sci.
, vol.59
, pp. 451-459
-
-
Kirischuk, S.1
Verkhratsky, A.2
-
7
-
-
0031816168
-
Increased calcium buffering in basal forebrain neurons during aging
-
Murchison D, Griffith WH. Increased calcium buffering in basal forebrain neurons during aging. J Neurophysiol. 1998;80:350-64.
-
(1998)
J Neurophysiol.
, vol.80
, pp. 350-364
-
-
Murchison, D.1
Griffith, W.H.2
-
8
-
-
0037115050
-
2+ homeostasis in aged cerebellar granule neurons in brain slices
-
2+ homeostasis in aged cerebellar granule neurons in brain slices. J Neurosci. 2002;22:10761-71.
-
(2002)
J Neurosci.
, vol.22
, pp. 10761-10771
-
-
Xiong, J.1
Verkhratsky, A.2
Toescu, E.C.3
-
9
-
-
0029789056
-
Aging changes in voltage-gated calcium currents in hippocampal CA1 neurons
-
Campbell LW, Hao SY, Thibault O, Blalock EM, Landfield PW. Aging changes in voltage-gated calcium currents in hippocampal CA1 neurons. J Neurosci. 1996;16:6286-95.
-
(1996)
J Neurosci.
, vol.16
, pp. 6286-6295
-
-
Campbell, L.W.1
Hao, S.Y.2
Thibault, O.3
Blalock, E.M.4
Landfield, P.W.5
-
10
-
-
0029782113
-
Increase in single L-type calcium channels in hippocampal neurons during aging
-
Thibault O, Landfield PW. Increase in single L-type calcium channels in hippocampal neurons during aging. Science. 1996;272:1017-20.
-
(1996)
Science.
, vol.272
, pp. 1017-1020
-
-
Thibault, O.1
Landfield, P.W.2
-
11
-
-
0029896492
-
High-voltage-activated calcium currents in basal forebrain neurons during aging
-
Murchison D, Griffith WH. High-voltage-activated calcium currents in basal forebrain neurons during aging. J Neurophysiol. 1996;76:158-74.
-
(1996)
J Neurophysiol.
, vol.76
, pp. 158-174
-
-
Murchison, D.1
Griffith, W.H.2
-
12
-
-
0031451847
-
2+-dependent processes: Relation to hippocampal synaptic plasticity
-
2+-dependent processes: relation to hippocampal synaptic plasticity. Hippocampus. 1997;7:602-12.
-
(1997)
Hippocampus.
, vol.7
, pp. 602-612
-
-
Foster, T.C.1
Norris, C.M.2
-
13
-
-
0036830947
-
Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease
-
LaFerla FM. Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease. Nat Rev Neurosci. 2002;3:862-72.
-
(2002)
Nat Rev Neurosci.
, vol.3
, pp. 862-872
-
-
Laferla, F.M.1
-
15
-
-
0037289779
-
Ca2+ signaling in mouse cortical neurons studied by two-photon imaging and photoreleased inositol triphosphate
-
Stutzmann GE, LaFerla FM, Parker I. Ca2+ signaling in mouse cortical neurons studied by two-photon imaging and photoreleased inositol triphosphate. J Neurosci. 2003;23:758-65.
-
(2003)
J Neurosci.
, vol.23
, pp. 758-765
-
-
Stutzmann, G.E.1
Laferla, F.M.2
Parker, I.3
-
16
-
-
33646945317
-
2+ disruptions in young, adult, and aged Alzheimer's disease mice
-
2+ disruptions in young, adult, and aged Alzheimer's disease mice. J Neurosci. 2006;26:5180-9.
-
(2006)
J Neurosci.
, vol.26
, pp. 5180-5189
-
-
Stutzmann, G.E.1
Smith, I.2
Caccamo, A.3
Oddo, S.4
Laferla, F.M.5
Parker, I.6
-
17
-
-
34247621471
-
Enhanced ryanodine-mediated calcium release in mutant PS1-expressing Alzheimer's mouse models
-
Stutzmann GE, Smith I, Caccamo A, Oddo S, Parker I, Laferla FM. Enhanced ryanodine-mediated calcium release in mutant PS1-expressing Alzheimer's mouse models. Ann N Y Acad Sci. 2007;1097:265-77.
-
(2007)
Ann N Y Acad Sci.
, vol.1097
, pp. 265-277
-
-
Stutzmann, G.E.1
Smith, I.2
Caccamo, A.3
Oddo, S.4
Parker, I.5
Laferla, F.M.6
-
19
-
-
0025342635
-
Two-photon laser scanning fluorescence microscopy
-
Denk W, Strickler JH, Webb WW. Two-photon laser scanning fluorescence microscopy. Science. 1990;248:73-6.
-
(1990)
Science.
, vol.248
, pp. 73-76
-
-
Denk, W.1
Strickler, J.H.2
Webb, W.W.3
-
20
-
-
0031021713
-
In vivo dendritic calcium dynamics in neocortical pyramidal neurons
-
Svoboda K, Denk W, Kleinfeld D, Tank DW. In vivo dendritic calcium dynamics in neocortical pyramidal neurons. Nature. 1997;385:161-5.
-
(1997)
Nature.
, vol.385
, pp. 161-165
-
-
Svoboda, K.1
Denk, W.2
Kleinfeld, D.3
Tank, D.W.4
-
21
-
-
30944450665
-
Deep tissue two-photon microscopy
-
Helmchen F, Denk W. Deep tissue two-photon microscopy. Nat Methods. 2005;2:932-40.
-
(2005)
Nat Methods.
, vol.2
, pp. 932-940
-
-
Helmchen, F.1
Denk, W.2
-
22
-
-
0035923747
-
Representation of odorants by receptor neuron input to the mouse olfactory bulb
-
Wachowiak M, Cohen LB. Representation of odorants by receptor neuron input to the mouse olfactory bulb. Neuron. 2001;32:723-35.
-
(2001)
Neuron.
, vol.32
, pp. 723-735
-
-
Wachowiak, M.1
Cohen, L.B.2
-
24
-
-
33751113978
-
Targeted bulk-loading of fluorescent indicators for two-photon brain imaging in vivo
-
Garaschuk O, Milos RI, Konnerth A. Targeted bulk-loading of fluorescent indicators for two-photon brain imaging in vivo. Nat Prot. 2006;1:380-6.
-
(2006)
Nat Prot.
, vol.1
, pp. 380-386
-
-
Garaschuk, O.1
Milos, R.I.2
Konnerth, A.3
-
26
-
-
33847628425
-
Improved calcium imaging in transgenic mice expressing a troponin-C based biosensor
-
Heim N, Garaschuk O, Friedrich MW, Mank M, Milos RI, Kovalchuk Y, et al. Improved calcium imaging in transgenic mice expressing a troponin-C based biosensor. Nat Methods. 2007;4:127-9.
-
(2007)
Nat Methods.
, vol.4
, pp. 127-129
-
-
Heim, N.1
Garaschuk, O.2
Friedrich, M.W.3
Mank, M.4
Milos, R.I.5
Kovalchuk, Y.6
-
27
-
-
34547952060
-
Troponin C-based biosensors: A new family of genetically encoded indicators for in vivo calcium imaging in the nervous system
-
Garaschuk O, Griesbeck O, Konnerth A. Troponin C-based biosensors: a new family of genetically encoded indicators for in vivo calcium imaging in the nervous system. Cell Calcium. 2007;42:351-61.
-
(2007)
Cell Calcium.
, vol.42
, pp. 351-361
-
-
Garaschuk, O.1
Griesbeck, O.2
Konnerth, A.3
-
28
-
-
33947187417
-
In vivo calcium imaging from genetically specified target cells in mouse cerebellum
-
Diez-Garcia J, Akemann W, Knopfel T. In vivo calcium imaging from genetically specified target cells in mouse cerebellum. Neuroimage. 2007;34:859-69.
-
(2007)
Neuroimage.
, vol.34
, pp. 859-869
-
-
Diez-Garcia, J.1
Akemann, W.2
Knopfel, T.3
-
32
-
-
5344277556
-
Deciphering the molecular basis of memory failure in Alzheimer's disease
-
Walsh DM, Selkoe DJ. Deciphering the molecular basis of memory failure in Alzheimer's disease. Neuron. 2004;44:181-93.
-
(2004)
Neuron.
, vol.44
, pp. 181-193
-
-
Walsh, D.M.1
Selkoe, D.J.2
-
33
-
-
0036548070
-
Gamma-secretase, notch, Abeta and Alzheimer's disease: Where do the presenilins fit in
-
Sisodia SS, St George-Hyslop PH. Gamma-secretase, notch, Abeta and Alzheimer's disease: where do the presenilins fit in. Nat Rev Neurosci. 2002;3:281-90.
-
(2002)
Nat Rev Neurosci.
, vol.3
, pp. 281-290
-
-
Sisodia, S.S.1
St George-Hyslop, P.H.2
-
34
-
-
33847662852
-
Soluble protein oligomers in neurodegeneration: Lessons from the Alzheimer's amyloid beta-peptide
-
Haass C, Selkoe DJ. Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide. Nat Rev Mol Cell Biol. 2007;8:101-12.
-
(2007)
Nat Rev Mol Cell Biol.
, vol.8
, pp. 101-112
-
-
Haass, C.1
Selkoe, D.J.2
-
35
-
-
0028985574
-
Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein
-
Games D, Adams D, Alessandrini R, Barbour R, Berthelette P, Blackwell C, et al. Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein. Nature. 1995;373:523-7.
-
(1995)
Nature.
, vol.373
, pp. 523-527
-
-
Games, D.1
Adams, D.2
Alessandrini, R.3
Barbour, R.4
Berthelette, P.5
Blackwell, C.6
-
36
-
-
0029742199
-
Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice
-
Hsiao K, Chapman P, Nilsen S, Eckman C, Harigaya Y, Younkin S, et al. Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice. Science. 1996;274:99-102.
-
(1996)
Science.
, vol.274
, pp. 99-102
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Eckman, C.4
Harigaya, Y.5
Younkin, S.6
-
37
-
-
0011444914
-
Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology
-
Sturchler-Pierrat C, Abramowski D, Duke M, Wiederhold KH, Mistl C, Rothacher S, et al. Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology. Proc Natl Acad Sci U S A. 1997;94:13287-92.
-
(1997)
Proc Natl Acad Sci U S A.
, vol.94
, pp. 13287-13292
-
-
Sturchler-Pierrat, C.1
Abramowski, D.2
Duke, M.3
Wiederhold, K.H.4
Mistl, C.5
Rothacher, S.6
-
38
-
-
0042697305
-
Triple-transgenic model of Alzheimer's disease with plaques and tangles: Intracellular Abeta and synaptic dysfunction
-
Oddo S, Caccamo A, Shepherd JD, Murphy MP, Golde TE, Kayed R, et al. Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction. Neuron. 2003;39:409-21.
-
(2003)
Neuron.
, vol.39
, pp. 409-421
-
-
Oddo, S.1
Caccamo, A.2
Shepherd, J.D.3
Murphy, M.P.4
Golde, T.E.5
Kayed, R.6
-
39
-
-
33748988258
-
Abeta42-driven cerebral amyloidosis in transgenic mice reveals early and robust pathology
-
Radde R, Bolmont T, Kaeser SA, Coomaraswamy J, Lindau D, Stoltze L, et al. Abeta42-driven cerebral amyloidosis in transgenic mice reveals early and robust pathology. EMBO Rep. 2006;7:940-6.
-
(2006)
EMBO Rep.
, vol.7
, pp. 940-946
-
-
Radde, R.1
Bolmont, T.2
Kaeser, S.A.3
Coomaraswamy, J.4
Lindau, D.5
Stoltze, L.6
-
40
-
-
0035116442
-
Growth arrest of individual senile plaques in a model of Alzheimer's disease observed by in vivo multiphoton microscopy
-
Christie RH, Bacskai BJ, Zipfel WR, Williams RM, Kajdasz ST, Webb WW, et al. Growth arrest of individual senile plaques in a model of Alzheimer's disease observed by in vivo multiphoton microscopy. J Neurosci. 2001;21:858-64.
-
(2001)
J Neurosci.
, vol.21
, pp. 858-864
-
-
Christie, R.H.1
Bacskai, B.J.2
Zipfel, W.R.3
Williams, R.M.4
Kajdasz, S.T.5
Webb, W.W.6
-
41
-
-
0142123057
-
Four-dimensional multiphoton imaging of brain entry, amyloid binding, and clearance of an amyloid-beta ligand in transgenic mice
-
Bacskai BJ, Hickey GA, Skoch J, Kajdasz ST, Wang Y, Huang GF, et al. Four-dimensional multiphoton imaging of brain entry, amyloid binding, and clearance of an amyloid-beta ligand in transgenic mice. Proc Natl Acad Sci U S A. 2003;100:12462-7.
-
(2003)
Proc Natl Acad Sci U S A.
, vol.100
, pp. 12462-12467
-
-
Bacskai, B.J.1
Hickey, G.A.2
Skoch, J.3
Kajdasz, S.T.4
Wang, Y.5
Huang, G.F.6
-
42
-
-
0037444553
-
In vivo imaging of reactive oxygen species specifically associated with thioflavine S-positive amyloid plaques by multiphoton microscopy
-
McLellan ME, Kajdasz ST, Hyman BT, Bacskai BJ. In vivo imaging of reactive oxygen species specifically associated with thioflavine S-positive amyloid plaques by multiphoton microscopy. J Neurosci. 2003;23:2212-7.
-
(2003)
J Neurosci.
, vol.23
, pp. 2212-2217
-
-
McLellan, M.E.1
Kajdasz, S.T.2
Hyman, B.T.3
Bacskai, B.J.4
-
43
-
-
0036707494
-
Imaging Abeta plaques in living transgenic mice with multiphoton microscopy and methoxy-X04, a systemically administered Congo red derivative
-
Klunk WE, Bacskai BJ, Mathis CA, Kajdasz ST, McLellan ME, Frosch MP, et al. Imaging Abeta plaques in living transgenic mice with multiphoton microscopy and methoxy-X04, a systemically administered Congo red derivative. J Neuropathol Exp Neurol. 2002;61:797-805.
-
(2002)
J Neuropathol Exp Neurol.
, vol.61
, pp. 797-805
-
-
Klunk, W.E.1
Bacskai, B.J.2
Mathis, C.A.3
Kajdasz, S.T.4
McLellan, M.E.5
Frosch, M.P.6
-
44
-
-
0035106780
-
Imaging of amyloid-beta deposits in brains of living mice permits direct observation of clearance of plaques with immunotherapy
-
Bacskai BJ, Kajdasz ST, Christie RH, Carter C, Games D, Seubert P, et al. Imaging of amyloid-beta deposits in brains of living mice permits direct observation of clearance of plaques with immunotherapy. Nat Med. 2001;7:369-72.
-
(2001)
Nat Med.
, vol.7
, pp. 369-372
-
-
Bacskai, B.J.1
Kajdasz, S.T.2
Christie, R.H.3
Carter, C.4
Games, D.5
Seubert, P.6
-
45
-
-
0032983536
-
Association of microglia with amyloid plaques in brains of APP23 transgenic mice
-
Stalder M, Phinney A, Probst A, Sommer B, Staufenbiel M, Jucker M. Association of microglia with amyloid plaques in brains of APP23 transgenic mice. Am J Pathol. 1999;154:1673-84.
-
(1999)
Am J Pathol.
, vol.154
, pp. 1673-1684
-
-
Stalder, M.1
Phinney, A.2
Probst, A.3
Sommer, B.4
Staufenbiel, M.5
Jucker, M.6
-
46
-
-
18744409106
-
Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo
-
Nimmerjahn A, Kirchhoff F, Kerr JN, Helmchen F. Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo. Nat Methods. 2004;1:31-7.
-
(2004)
Nat Methods.
, vol.1
, pp. 31-37
-
-
Nimmerjahn, A.1
Kirchhoff, F.2
Kerr, J.N.3
Helmchen, F.4
-
47
-
-
0034028817
-
Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion
-
Jung S, Aliberti J, Graemmel P, Sunshine MJ, Kreutzberg GW, Sher A, et al. Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion. Mol Cell Biol. 2000;20:4106-14.
-
(2000)
Mol Cell Biol.
, vol.20
, pp. 4106-4114
-
-
Jung, S.1
Aliberti, J.2
Graemmel, P.3
Sunshine, M.J.4
Kreutzberg, G.W.5
Sher, A.6
-
48
-
-
25444469608
-
Visualization of microglia in living tissues using Iba1-EGFP transgenic mice
-
Hirasawa T, Ohsawa K, Imai Y, Ondo Y, Akazawa C, Uchino S, et al. Visualization of microglia in living tissues using Iba1-EGFP transgenic mice. J Neurosci Res. 2005;81:357-62.
-
(2005)
J Neurosci Res.
, vol.81
, pp. 357-362
-
-
Hirasawa, T.1
Ohsawa, K.2
Imai, Y.3
Ondo, Y.4
Akazawa, C.5
Uchino, S.6
-
49
-
-
0018763698
-
Autofluorescence of viable cultured mammalian cells
-
Aubin JE. Autofluorescence of viable cultured mammalian cells. J Histochem Cytochem. 1979;27:36-43.
-
(1979)
J Histochem Cytochem.
, vol.27
, pp. 36-43
-
-
Aubin, J.E.1
-
50
-
-
0036241090
-
Pigments in aging: An overview
-
Porta EA. Pigments in aging: an overview. Ann N Y Acad Sci. 2002;959:57-65.
-
(2002)
Ann N Y Acad Sci.
, vol.959
, pp. 57-65
-
-
Porta, E.A.1
-
52
-
-
0036710928
-
Lipofuscin: Mechanisms of age-related accumulation and influence on cell function
-
Brunk UT, Terman A. Lipofuscin: mechanisms of age-related accumulation and influence on cell function. Free Radic Biol Med. 2002;33:611-9.
-
(2002)
Free Radic Biol Med.
, vol.33
, pp. 611-619
-
-
Brunk, U.T.1
Terman, A.2
-
53
-
-
33744475390
-
Two-photon excited autofluorescence imaging of human retinal pigment epithelial cells
-
Han M, Bindewald-Wittich A, Holz FG, Giese G, Niemz MH, Snyder S, et al. Two-photon excited autofluorescence imaging of human retinal pigment epithelial cells. J Biomed Opt. 2006;11:0105011-3.
-
(2006)
J Biomed Opt.
, vol.11
, pp. 0105011-0105013
-
-
Han, M.1
Bindewald-Wittich, A.2
Holz, F.G.3
Giese, G.4
Niemz, M.H.5
Snyder, S.6
-
54
-
-
33750586787
-
Two-photon-excited fluorescence imaging of human RPE cells with a femtosecond Ti:Sapphire laser
-
Bindewald-Wittich A, Han M, Schmitz-Valckenberg S, Snyder SR, Giese G, Bille JF, et al. Two-photon-excited fluorescence imaging of human RPE cells with a femtosecond Ti:Sapphire laser. Invest Ophthalmol Vis Sci. 2006;47:4553-7.
-
(2006)
Invest Ophthalmol Vis Sci.
, vol.47
, pp. 4553-4557
-
-
Bindewald-Wittich, A.1
Han, M.2
Schmitz-Valckenberg, S.3
Snyder, S.R.4
Giese, G.5
Bille, J.F.6
-
55
-
-
0002018965
-
Two-photon cross sections of indicators
-
Cold Spring Harbor Press Cold Spring Harbor
-
Xu C. Two-photon cross sections of indicators. In: Yuste R, Konnerth A, editors. Imaging: a laboratory manual. Cold Spring Harbor: Cold Spring Harbor Press; 2000. pp 19.1-19.9.
-
(2000)
Imaging: A Laboratory Manual
, pp. 191-199
-
-
Xu, C.1
Yuste, R.2
Konnerth, A.3
-
56
-
-
33751117722
-
Optical monitoring of brain function in vivo: From neurons to networks
-
Garaschuk O, Milos RI, Grienberger C, Marandi N, Adelsberger H, Konnerth A, et al. Optical monitoring of brain function in vivo: from neurons to networks. Pflugers Arch. 2006;453:385-96.
-
(2006)
Pflugers Arch.
, vol.453
, pp. 385-396
-
-
Garaschuk, O.1
Milos, R.I.2
Grienberger, C.3
Marandi, N.4
Adelsberger, H.5
Konnerth, A.6
|