메뉴 건너뛰기




Volumn 7, Issue 2, 2008, Pages 106-113

Osteoarthritis in the context of ageing and evolution. Loss of chondrocyte differentiation block during ageing

Author keywords

Cartilage; Chondrocytes; Osteoarthritis; Terminal differentiation

Indexed keywords

GROWTH FACTOR; REACTIVE OXYGEN METABOLITE; TRANSFORMING GROWTH FACTOR BETA;

EID: 41049117461     PISSN: 15681637     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.arr.2007.10.001     Document Type: Short Survey
Times cited : (72)

References (71)
  • 1
    • 33750870364 scopus 로고    scopus 로고
    • Gene expression and proliferation analysis in young, aged, and osteoarthritic sheep chondrocytes effect of growth factor treatment
    • Acosta C.A., Izal I., Ripalda P., Douglas-Price A.L., and Forriol F. Gene expression and proliferation analysis in young, aged, and osteoarthritic sheep chondrocytes effect of growth factor treatment. J. Orthop. Res. 24 November (11) (2006) 2087-2094
    • (2006) J. Orthop. Res. , vol.24 , Issue.November 11 , pp. 2087-2094
    • Acosta, C.A.1    Izal, I.2    Ripalda, P.3    Douglas-Price, A.L.4    Forriol, F.5
  • 2
    • 0036675540 scopus 로고    scopus 로고
    • Apoptosis and cellular vitality: issues in osteoarthritic cartilage degeneration
    • Aigner T., and Kim H.A. Apoptosis and cellular vitality: issues in osteoarthritic cartilage degeneration. Arthritis Rheum. 46 August (8) (2002) 1986-1996
    • (2002) Arthritis Rheum. , vol.46 , Issue.August 8 , pp. 1986-1996
    • Aigner, T.1    Kim, H.A.2
  • 3
    • 0036707739 scopus 로고    scopus 로고
    • Roles of chondrocytes in the pathogenesis of osteoarthritis
    • Aigner T., Kurz B., Fukui N., and Sandell L. Roles of chondrocytes in the pathogenesis of osteoarthritis. Curr. Opin. Rheumatol. 14 September (5) (2002) 578-584
    • (2002) Curr. Opin. Rheumatol. , vol.14 , Issue.September 5 , pp. 578-584
    • Aigner, T.1    Kurz, B.2    Fukui, N.3    Sandell, L.4
  • 4
    • 4344604554 scopus 로고    scopus 로고
    • Aging theories of primary osteoarthritis: from epidemiology to molecular biology
    • Aigner T., Rose J., Martin J., and Buckwalter J. Aging theories of primary osteoarthritis: from epidemiology to molecular biology. Rejuvenation Res. 7 2 (2004) 134-145
    • (2004) Rejuvenation Res. , vol.7 , Issue.2 , pp. 134-145
    • Aigner, T.1    Rose, J.2    Martin, J.3    Buckwalter, J.4
  • 5
    • 0032519990 scopus 로고    scopus 로고
    • Ageing and zonal variation in post-translational modification of collagen in normal human articular cartilage. The age-related increase in non-enzymatic glycation affects biomechanical properties of cartilage
    • Bank R.A., Bayliss M.T., Lafeber F.P., Maroudas A., and TeKoppele J.M. Ageing and zonal variation in post-translational modification of collagen in normal human articular cartilage. The age-related increase in non-enzymatic glycation affects biomechanical properties of cartilage. Biochem. J. 330 Feb (Pt 1) (1998) 345-351
    • (1998) Biochem. J. , vol.330 , Issue.Feb PART 1 , pp. 345-351
    • Bank, R.A.1    Bayliss, M.T.2    Lafeber, F.P.3    Maroudas, A.4    TeKoppele, J.M.5
  • 6
    • 0021591661 scopus 로고
    • Changes in the cartilage proteoglycans in relation to age and osteoarthrosis
    • Bihari-Varga M., Farkas T., and Biro T. Changes in the cartilage proteoglycans in relation to age and osteoarthrosis. Acta Biol. Hung. 35 2-4 (1984) 325-331
    • (1984) Acta Biol. Hung. , vol.35 , Issue.2-4 , pp. 325-331
    • Bihari-Varga, M.1    Farkas, T.2    Biro, T.3
  • 7
    • 0031886742 scopus 로고    scopus 로고
    • Osteoarthritis chondrocytes die by apoptosis. A possible pathway for osteoarthritis pathology
    • Blanco F.J., Guitian R., Vazquez-Martul E., de Toro F.J., and Galdo F. Osteoarthritis chondrocytes die by apoptosis. A possible pathway for osteoarthritis pathology. Arthritis Rheum. 41 Feb (2) (1998) 284-289
    • (1998) Arthritis Rheum. , vol.41 , Issue.Feb 2 , pp. 284-289
    • Blanco, F.J.1    Guitian, R.2    Vazquez-Martul, E.3    de Toro, F.J.4    Galdo, F.5
  • 9
    • 33646145514 scopus 로고    scopus 로고
    • Premature osteoarthritis in the Disproportionate micromelia (Dmm) mouse
    • Bomsta B.D., Bridgewater L.C., and Seegmiller R.E. Premature osteoarthritis in the Disproportionate micromelia (Dmm) mouse. Osteoarthritis Cartilage 14 May (5) (2006) 477-485
    • (2006) Osteoarthritis Cartilage , vol.14 , Issue.May 5 , pp. 477-485
    • Bomsta, B.D.1    Bridgewater, L.C.2    Seegmiller, R.E.3
  • 10
    • 0031602467 scopus 로고    scopus 로고
    • Articular cartilage: degeneration and osteoarthritis, repair, regeneration, and transplantation
    • Buckwalter J.A., and Mankin H.J. Articular cartilage: degeneration and osteoarthritis, repair, regeneration, and transplantation. Instr. Course Lect. 47 (1998) 487-504
    • (1998) Instr. Course Lect. , vol.47 , pp. 487-504
    • Buckwalter, J.A.1    Mankin, H.J.2
  • 11
    • 34547945100 scopus 로고    scopus 로고
    • Prevention of oxidative damage that contributes to the loss of bioenergetic capacity in ageing skin
    • Corstjens H., Declercq L., Hellemans L., Sente I., and Maes D. Prevention of oxidative damage that contributes to the loss of bioenergetic capacity in ageing skin. Exp. Gerontol. 42 september 9 (2007) 924-929
    • (2007) Exp. Gerontol. , vol.42 , Issue.september 9 , pp. 924-929
    • Corstjens, H.1    Declercq, L.2    Hellemans, L.3    Sente, I.4    Maes, D.5
  • 12
    • 0037148521 scopus 로고    scopus 로고
    • Bone abnormalities in latent TGF-[beta] binding protein (Ltbp)-3-null mice indicate a role for Ltbp-3 in modulating TGF-[beta] bioavailability
    • Dabovic B., Chen Y., Colarossi C., Obata H., Zambuto L., Perle M.A., et al. Bone abnormalities in latent TGF-[beta] binding protein (Ltbp)-3-null mice indicate a role for Ltbp-3 in modulating TGF-[beta] bioavailability. J. Cell Biol. 156 January (2) (2002) 227-232
    • (2002) J. Cell Biol. , vol.156 , Issue.January 2 , pp. 227-232
    • Dabovic, B.1    Chen, Y.2    Colarossi, C.3    Obata, H.4    Zambuto, L.5    Perle, M.A.6
  • 13
    • 33750591504 scopus 로고    scopus 로고
    • Dysfunction of TGF-beta signaling in Alzheimer's disease
    • Das P., and Golde T. Dysfunction of TGF-beta signaling in Alzheimer's disease. J. Clin. Invest. 116 November (11) (2006) 2855-2857
    • (2006) J. Clin. Invest. , vol.116 , Issue.November 11 , pp. 2855-2857
    • Das, P.1    Golde, T.2
  • 14
    • 2342648312 scopus 로고    scopus 로고
    • The AGE of the matrix: chemistry, consequence and cure
    • DeGroot J. The AGE of the matrix: chemistry, consequence and cure. Curr. Opin. Pharmacol. 4 June (3) (2004) 301-305
    • (2004) Curr. Opin. Pharmacol. , vol.4 , Issue.June 3 , pp. 301-305
    • DeGroot, J.1
  • 15
    • 0035159518 scopus 로고    scopus 로고
    • Accumulation of advanced glycation endproducts reduces chondrocyte-mediated extracellular matrix turnover in human articular cartilage
    • DeGroot J., Verzijl N., Jacobs K.M., Budde M., Bank R.A., Bijlsma J.W., et al. Accumulation of advanced glycation endproducts reduces chondrocyte-mediated extracellular matrix turnover in human articular cartilage. Osteoarthritis Cartilage 9 November (8) (2001) 720-726
    • (2001) Osteoarthritis Cartilage , vol.9 , Issue.November 8 , pp. 720-726
    • DeGroot, J.1    Verzijl, N.2    Jacobs, K.M.3    Budde, M.4    Bank, R.A.5    Bijlsma, J.W.6
  • 16
    • 11144357921 scopus 로고    scopus 로고
    • Accumulation of advanced glycation end products as a molecular mechanism for aging as a risk factor in osteoarthritis
    • DeGroot J., Verzijl N., Wenting-van Wijk M.J., Jacobs K.M., Van E.B., Van Roermund P.M., et al. Accumulation of advanced glycation end products as a molecular mechanism for aging as a risk factor in osteoarthritis. Arthritis Rheum. 50 April (4) (2004) 1207-1215
    • (2004) Arthritis Rheum. , vol.50 , Issue.April 4 , pp. 1207-1215
    • DeGroot, J.1    Verzijl, N.2    Wenting-van Wijk, M.J.3    Jacobs, K.M.4    Van, E.B.5    Van Roermund, P.M.6
  • 17
    • 25644437811 scopus 로고    scopus 로고
    • Increased matrix metalloproteinase-13 production with aging by human articular chondrocytes in response to catabolic stimuli
    • Forsyth C.B., Cole A., Murphy G., Bienias J.L., Im H.J., and Loeser Jr. R.F. Increased matrix metalloproteinase-13 production with aging by human articular chondrocytes in response to catabolic stimuli. J. Gerontol. A Biol. Sci. Med. Sci. 60 September (9) (2005) 1118-1124
    • (2005) J. Gerontol. A Biol. Sci. Med. Sci. , vol.60 , Issue.September 9 , pp. 1118-1124
    • Forsyth, C.B.1    Cole, A.2    Murphy, G.3    Bienias, J.L.4    Im, H.J.5    Loeser Jr., R.F.6
  • 18
    • 33746956085 scopus 로고    scopus 로고
    • Signaling through the small G-protein Cdc42 is involved in insulin-like growth factor-I resistance in aging articular chondrocytes
    • Fortier L.A., and Miller B.J. Signaling through the small G-protein Cdc42 is involved in insulin-like growth factor-I resistance in aging articular chondrocytes. J. Orthop. Res. 24 August (8) (2006) 1765-1772
    • (2006) J. Orthop. Res. , vol.24 , Issue.August 8 , pp. 1765-1772
    • Fortier, L.A.1    Miller, B.J.2
  • 19
    • 0029166857 scopus 로고
    • Growth factor responsiveness of human articular chondrocytes in aging and development
    • Guerne P.A., Blanco F., Kaelin A., Desgeorges A., and Lotz M. Growth factor responsiveness of human articular chondrocytes in aging and development. Arthritis Rheum. 38 July (7) (1995) 960-968
    • (1995) Arthritis Rheum. , vol.38 , Issue.July 7 , pp. 960-968
    • Guerne, P.A.1    Blanco, F.2    Kaelin, A.3    Desgeorges, A.4    Lotz, M.5
  • 20
    • 0015210527 scopus 로고
    • The palaeopathology of animal skeletal remains
    • Harcourt R.A. The palaeopathology of animal skeletal remains. Vet. Rec. 89 September (10) (1971) 267-272
    • (1971) Vet. Rec. , vol.89 , Issue.September 10 , pp. 267-272
    • Harcourt, R.A.1
  • 21
    • 0031658981 scopus 로고    scopus 로고
    • Linkage of chondrocyte apoptosis and cartilage degradation in human osteoarthritis
    • Hashimoto S., Ochs R.L., Komiya S., and Lotz M. Linkage of chondrocyte apoptosis and cartilage degradation in human osteoarthritis. Arthritis Rheum. 41 September (9) (1998) 1632-1638
    • (1998) Arthritis Rheum. , vol.41 , Issue.September 9 , pp. 1632-1638
    • Hashimoto, S.1    Ochs, R.L.2    Komiya, S.3    Lotz, M.4
  • 22
    • 22644441306 scopus 로고    scopus 로고
    • Oxygen and reactive oxygen species in cartilage degradation: friends or foes?
    • Henrotin Y., Kurz B., and Aigner T. Oxygen and reactive oxygen species in cartilage degradation: friends or foes?. Osteoarthritis Cartilage 13 August (8) (2005) 643-654
    • (2005) Osteoarthritis Cartilage , vol.13 , Issue.August 8 , pp. 643-654
    • Henrotin, Y.1    Kurz, B.2    Aigner, T.3
  • 23
    • 0019831921 scopus 로고
    • Decline in respiratory control ratio of rat liver mitochondria in old age
    • Horton A.A., and Spencer J.A. Decline in respiratory control ratio of rat liver mitochondria in old age. Mech. Ageing Dev. 17 November (3) (1981) 253-259
    • (1981) Mech. Ageing Dev. , vol.17 , Issue.November 3 , pp. 253-259
    • Horton, A.A.1    Spencer, J.A.2
  • 24
    • 33644673437 scopus 로고    scopus 로고
    • A novel role for GADD45beta as a mediator of MMP-13 gene expression during chondrocyte terminal differentiation
    • Ijiri K., Zerbini L.F., Peng H., Correa R.G., Lu B., Walsh N., et al. A novel role for GADD45beta as a mediator of MMP-13 gene expression during chondrocyte terminal differentiation. J. Biol. Chem. 280 November (46) (2005) 38544-38555
    • (2005) J. Biol. Chem. , vol.280 , Issue.November 46 , pp. 38544-38555
    • Ijiri, K.1    Zerbini, L.F.2    Peng, H.3    Correa, R.G.4    Lu, B.5    Walsh, N.6
  • 25
    • 10344245561 scopus 로고    scopus 로고
    • Critical roles for collagenase-3 (Mmp13) in development of growth plate cartilage and in endochondral ossification
    • Inada M., Wang Y., Byrne M.H., Rahman M.U., Miyaura C., Lopez-Otin C., et al. Critical roles for collagenase-3 (Mmp13) in development of growth plate cartilage and in endochondral ossification. Proc. Natl. Acad. Sci. U.S.A. 101 December (49) (2004) 17192-17197
    • (2004) Proc. Natl. Acad. Sci. U.S.A. , vol.101 , Issue.December 49 , pp. 17192-17197
    • Inada, M.1    Wang, Y.2    Byrne, M.H.3    Rahman, M.U.4    Miyaura, C.5    Lopez-Otin, C.6
  • 26
    • 0033939459 scopus 로고    scopus 로고
    • Mitochondrial oxidative phosphorylation is a downstream regulator of nitric oxide effects on chondrocyte matrix synthesis and mineralization
    • Johnson K., Jung A., Murphy A., Andreyev A., Dykens J., and Terkeltaub R. Mitochondrial oxidative phosphorylation is a downstream regulator of nitric oxide effects on chondrocyte matrix synthesis and mineralization. Arthritis Rheum. 43 July (7) (2000) 1560-1570
    • (2000) Arthritis Rheum. , vol.43 , Issue.July 7 , pp. 1560-1570
    • Johnson, K.1    Jung, A.2    Murphy, A.3    Andreyev, A.4    Dykens, J.5    Terkeltaub, R.6
  • 27
    • 1842683010 scopus 로고    scopus 로고
    • Mediation of spontaneous knee osteoarthritis by progressive chondrocyte ATP depletion in Hartley guinea pigs
    • Johnson K., Svensson C.I., Etten D.V., Ghosh S.S., Murphy A.N., Powell H.C., et al. Mediation of spontaneous knee osteoarthritis by progressive chondrocyte ATP depletion in Hartley guinea pigs. Arthritis Rheum. 50 April (4) (2004) 1216-1225
    • (2004) Arthritis Rheum. , vol.50 , Issue.April 4 , pp. 1216-1225
    • Johnson, K.1    Svensson, C.I.2    Etten, D.V.3    Ghosh, S.S.4    Murphy, A.N.5    Powell, H.C.6
  • 29
    • 0022616354 scopus 로고
    • Reduction of passive extension and radiographic evidence of degenerative knee joint diseases in cage-raised and free-ranging aged rhesus monkeys (Macaca mulatta)
    • Kessler M.J., Turnquist J.E., Pritzker K.P., and London W.T. Reduction of passive extension and radiographic evidence of degenerative knee joint diseases in cage-raised and free-ranging aged rhesus monkeys (Macaca mulatta). J. Med. Primatol. 15 1 (1986) 1-9
    • (1986) J. Med. Primatol. , vol.15 , Issue.1 , pp. 1-9
    • Kessler, M.J.1    Turnquist, J.E.2    Pritzker, K.P.3    London, W.T.4
  • 30
    • 0037523033 scopus 로고    scopus 로고
    • Apoptotic chondrocyte death in human osteoarthritis
    • Kim H.A., Lee Y.J., Seong S.C., Choe K.W., and Song Y.W. Apoptotic chondrocyte death in human osteoarthritis. J. Rheumatol. 27 February (2) (2000) 455-462
    • (2000) J. Rheumatol. , vol.27 , Issue.February 2 , pp. 455-462
    • Kim, H.A.1    Lee, Y.J.2    Seong, S.C.3    Choe, K.W.4    Song, Y.W.5
  • 31
    • 18744437369 scopus 로고    scopus 로고
    • Aggrecan degradation in human cartilage. Evidence for both matrix metalloproteinase and aggrecanase activity in normal, osteoarthritic, and rheumatoid joints
    • Lark M.W., Bayne E.K., Flanagan J., Harper C.F., Hoerrner L.A., Hutchinson N.I., et al. Aggrecan degradation in human cartilage. Evidence for both matrix metalloproteinase and aggrecanase activity in normal, osteoarthritic, and rheumatoid joints. J. Clin. Invest. 100 July (1) (1997) 93-106
    • (1997) J. Clin. Invest. , vol.100 , Issue.July 1 , pp. 93-106
    • Lark, M.W.1    Bayne, E.K.2    Flanagan, J.3    Harper, C.F.4    Hoerrner, L.A.5    Hutchinson, N.I.6
  • 32
    • 29644432280 scopus 로고    scopus 로고
    • Smad3-deficient chondrocytes have enhanced BMP signaling and accelerated differentiation
    • Li T.F., Darowish M., Zuscik M.J., Chen D., Schwarz E.M., Rosier R.N., et al. Smad3-deficient chondrocytes have enhanced BMP signaling and accelerated differentiation. J. Bone Miner. Res. 21 January (1) (2006) 4-16
    • (2006) J. Bone Miner. Res. , vol.21 , Issue.January 1 , pp. 4-16
    • Li, T.F.1    Darowish, M.2    Zuscik, M.J.3    Chen, D.4    Schwarz, E.M.5    Rosier, R.N.6
  • 33
    • 30944456312 scopus 로고    scopus 로고
    • Molecular and cellular characterization during chondrogenic differentiation of adipose tissue-derived stromal cells in vitro and cartilage formation in vivo
    • Lin Y., Luo E., Chen X., Liu L., Qiao J., Yan Z., et al. Molecular and cellular characterization during chondrogenic differentiation of adipose tissue-derived stromal cells in vitro and cartilage formation in vivo. J.Cell Mol. Med. 9 October (4) (2005) 929-939
    • (2005) J.Cell Mol. Med. , vol.9 , Issue.October 4 , pp. 929-939
    • Lin, Y.1    Luo, E.2    Chen, X.3    Liu, L.4    Qiao, J.5    Yan, Z.6
  • 34
    • 0033680154 scopus 로고    scopus 로고
    • Reduction in the chondrocyte response to insulin-like growth factor 1 in aging and osteoarthritis: studies in a non-human primate model of naturally occurring disease
    • Loeser R.F., Shanker G., Carlson C.S., Gardin J.F., Shelton B.J., and Sonntag W.E. Reduction in the chondrocyte response to insulin-like growth factor 1 in aging and osteoarthritis: studies in a non-human primate model of naturally occurring disease. Arthritis Rheum. 43 September (9) (2000) 2110-2120
    • (2000) Arthritis Rheum. , vol.43 , Issue.September 9 , pp. 2110-2120
    • Loeser, R.F.1    Shanker, G.2    Carlson, C.S.3    Gardin, J.F.4    Shelton, B.J.5    Sonntag, W.E.6
  • 35
    • 0036745073 scopus 로고    scopus 로고
    • Detection of nitrotyrosine in aging and osteoarthritic cartilage: Correlation of oxidative damage with the presence of interleukin-1beta and with chondrocyte resistance to insulin-like growth factor 1
    • Loeser R.F., Carlson C.S., Del C.M., and Cole A. Detection of nitrotyrosine in aging and osteoarthritic cartilage: Correlation of oxidative damage with the presence of interleukin-1beta and with chondrocyte resistance to insulin-like growth factor 1. Arthritis Rheum. 46 September (9) (2002) 2349-2357
    • (2002) Arthritis Rheum. , vol.46 , Issue.September 9 , pp. 2349-2357
    • Loeser, R.F.1    Carlson, C.S.2    Del, C.M.3    Cole, A.4
  • 36
    • 23644436200 scopus 로고    scopus 로고
    • Articular chondrocytes express the receptor for advanced glycation end products: Potential role in osteoarthritis
    • Loeser R.F., Yammani R.R., Carlson C.S., Chen H., Cole A., Im H.J., et al. Articular chondrocytes express the receptor for advanced glycation end products: Potential role in osteoarthritis. Arthritis Rheum. 52 August (8) (2005) 2376-2385
    • (2005) Arthritis Rheum. , vol.52 , Issue.August 8 , pp. 2376-2385
    • Loeser, R.F.1    Yammani, R.R.2    Carlson, C.S.3    Chen, H.4    Cole, A.5    Im, H.J.6
  • 37
    • 0033166579 scopus 로고    scopus 로고
    • Mechanisms of chondrocyte apoptosis
    • Lotz M., Hashimoto S., and Kuhn K. Mechanisms of chondrocyte apoptosis. Osteoarthritis Cartilage 7 July (4) (1999) 389-391
    • (1999) Osteoarthritis Cartilage , vol.7 , Issue.July 4 , pp. 389-391
    • Lotz, M.1    Hashimoto, S.2    Kuhn, K.3
  • 38
    • 33845287590 scopus 로고    scopus 로고
    • Bioluminescence imaging of Smad signaling in living mice shows correlation with excitotoxic neurodegeneration
    • Luo J., Lin A.H., Masliah E., and Wyss-Coray T. Bioluminescence imaging of Smad signaling in living mice shows correlation with excitotoxic neurodegeneration. Proc. Natl. Acad. Sci. U.S.A. 103 November (48) (2006) 18326-18331
    • (2006) Proc. Natl. Acad. Sci. U.S.A. , vol.103 , Issue.November 48 , pp. 18326-18331
    • Luo, J.1    Lin, A.H.2    Masliah, E.3    Wyss-Coray, T.4
  • 39
    • 0014483931 scopus 로고
    • The arthritides, a medicolegal review. Osteoarthritis (degenerative, hypertrophic, senescent, or "wear and tear" arthritis)
    • Marmor D. The arthritides, a medicolegal review. Osteoarthritis (degenerative, hypertrophic, senescent, or "wear and tear" arthritis). Med. Trial Tech. Q 15 March (3) (1969) 37-58
    • (1969) Med. Trial Tech. Q , vol.15 , Issue.March 3 , pp. 37-58
    • Marmor, D.1
  • 40
    • 0038753871 scopus 로고    scopus 로고
    • The role of chondrocyte senescence in the pathogenesis of osteoarthritis and in limiting cartilage repair
    • Martin J.A., and Buckwalter J.A. The role of chondrocyte senescence in the pathogenesis of osteoarthritis and in limiting cartilage repair. J. Bone Joint Surg. Am. 85-A Suppl. 2 (2003) 106-110
    • (2003) J. Bone Joint Surg. Am. , vol.85 -A , Issue.SUPPL. 2 , pp. 106-110
    • Martin, J.A.1    Buckwalter, J.A.2
  • 41
    • 0036398455 scopus 로고    scopus 로고
    • Aging articular cartilage chondrocyte senescence and osteoarthritis
    • Martin J.A., and Buckwalter J.A. Aging articular cartilage chondrocyte senescence and osteoarthritis. Biogerontology 3 5 (2002) 257-264
    • (2002) Biogerontology , vol.3 , Issue.5 , pp. 257-264
    • Martin, J.A.1    Buckwalter, J.A.2
  • 42
    • 1842781743 scopus 로고    scopus 로고
    • Effects of oxidative damage and telomerase activity on human articular cartilage chondrocyte senescence
    • Martin J.A., Klingelhutz A.J., Moussavi-Harami F., and Buckwalter J.A. Effects of oxidative damage and telomerase activity on human articular cartilage chondrocyte senescence. J. Gerontol. A Biol. Sci. Med. Sci. 59 April (4) (2004) 324-337
    • (2004) J. Gerontol. A Biol. Sci. Med. Sci. , vol.59 , Issue.April 4 , pp. 324-337
    • Martin, J.A.1    Klingelhutz, A.J.2    Moussavi-Harami, F.3    Buckwalter, J.A.4
  • 43
    • 0030032444 scopus 로고    scopus 로고
    • Cloning, expression, and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilage
    • Mitchell P.G., Magna H.A., Reeves L.M., Lopresti-Morrow L.L., Yocum S.A., Rosner P.J., et al. Cloning, expression, and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilage. J. Clin. Invest. 97 February (3) (1996) 761-768
    • (1996) J. Clin. Invest. , vol.97 , Issue.February 3 , pp. 761-768
    • Mitchell, P.G.1    Magna, H.A.2    Reeves, L.M.3    Lopresti-Morrow, L.L.4    Yocum, S.A.5    Rosner, P.J.6
  • 44
    • 0030868574 scopus 로고    scopus 로고
    • Collagenase-3 (matrix metalloprotease 13) is preferentially localized in the deep layer of human arthritic cartilage in situ: in vitro mimicking effect by transforming growth factor beta
    • Moldovan F., Pelletier J.P., Hambor J., Cloutier J.M., and Martel-Pelletier J. Collagenase-3 (matrix metalloprotease 13) is preferentially localized in the deep layer of human arthritic cartilage in situ: in vitro mimicking effect by transforming growth factor beta. Arthritis Rheum. 40 September (9) (1997) 1653-1661
    • (1997) Arthritis Rheum. , vol.40 , Issue.September 9 , pp. 1653-1661
    • Moldovan, F.1    Pelletier, J.P.2    Hambor, J.3    Cloutier, J.M.4    Martel-Pelletier, J.5
  • 45
    • 0029166050 scopus 로고
    • Mutations in collagen genes resulting in metaphyseal and epiphyseal dysplasias
    • Olsen B.R. Mutations in collagen genes resulting in metaphyseal and epiphyseal dysplasias. Bone 17 August (2 Suppl.) (1995) 45S-49S
    • (1995) Bone , vol.17 , Issue.August 2 SUPPL.
    • Olsen, B.R.1
  • 46
    • 0025102770 scopus 로고
    • Hypertrophic chondrocytes. The terminal stage of differentiation in the chondrogenic cell lineage?
    • Pacifici M., Golden E.B., Oshima O., Shapiro I.M., Leboy P.S., and Adams S.L. Hypertrophic chondrocytes. The terminal stage of differentiation in the chondrogenic cell lineage?. Ann. N.Y. Acad. Sci. 599 (1990) 45-57
    • (1990) Ann. N.Y. Acad. Sci. , vol.599 , pp. 45-57
    • Pacifici, M.1    Golden, E.B.2    Oshima, O.3    Shapiro, I.M.4    Leboy, P.S.5    Adams, S.L.6
  • 47
    • 0024625193 scopus 로고
    • Natural selection, dietary restriction, and extended longevity
    • Phelan J.P., and Austad S.N. Natural selection, dietary restriction, and extended longevity. Growth Dev. Aging 53 1-2 (1989) 4-6
    • (1989) Growth Dev. Aging , vol.53 , Issue.1-2 , pp. 4-6
    • Phelan, J.P.1    Austad, S.N.2
  • 48
    • 0343502991 scopus 로고    scopus 로고
    • Lineage-dependent collagen expression and assembly during osteogenic or chondrogenic differentiation of a mesoblastic cell line
    • Poliard A., Ronziere M.C., Freyria A.M., Lamblin D., Herbage D., and Kellermann O. Lineage-dependent collagen expression and assembly during osteogenic or chondrogenic differentiation of a mesoblastic cell line. Exp. Cell Res. 253 December (2) (1999) 385-395
    • (1999) Exp. Cell Res. , vol.253 , Issue.December 2 , pp. 385-395
    • Poliard, A.1    Ronziere, M.C.2    Freyria, A.M.3    Lamblin, D.4    Herbage, D.5    Kellermann, O.6
  • 49
    • 33746362910 scopus 로고    scopus 로고
    • Osteoarthritis is for the birds
    • Rothschild B.M., and Panza R. Osteoarthritis is for the birds. Clin. Rheumatol. 25 September (5) (2006) 645-647
    • (2006) Clin. Rheumatol. , vol.25 , Issue.September 5 , pp. 645-647
    • Rothschild, B.M.1    Panza, R.2
  • 50
    • 33947175117 scopus 로고    scopus 로고
    • Increased collagen and aggrecan degradation with age in the joints of Timp3(-/-) mice
    • Sahebjam S., Khokha R., and Mort J.S. Increased collagen and aggrecan degradation with age in the joints of Timp3(-/-) mice. Arthritis Rheum. 56 Mar (3) (2007) 905-909
    • (2007) Arthritis Rheum. , vol.56 , Issue.Mar 3 , pp. 905-909
    • Sahebjam, S.1    Khokha, R.2    Mort, J.S.3
  • 51
    • 0036893256 scopus 로고    scopus 로고
    • Loss of transforming growth factor counteraction on interleukin 1 mediated effects in cartilage of old mice
    • Scharstuhl A., van Beuningen H.M., Vitters E.L., van der Kraan P.M., and van den Berg W.B. Loss of transforming growth factor counteraction on interleukin 1 mediated effects in cartilage of old mice. Ann. Rheum. Dis. 61 December (12) (2002) 1095-1098
    • (2002) Ann. Rheum. Dis. , vol.61 , Issue.December 12 , pp. 1095-1098
    • Scharstuhl, A.1    van Beuningen, H.M.2    Vitters, E.L.3    van der Kraan, P.M.4    van den Berg, W.B.5
  • 52
    • 0030727351 scopus 로고    scopus 로고
    • Expression of a truncated, kinase-defective TGF-beta type II receptor in mouse skeletal tissue promotes terminal chondrocyte differentiation and osteoarthritis
    • Serra R., Johnson M., Filvaroff E.H., LaBorde J., Sheehan D.M., Derynck R., et al. Expression of a truncated, kinase-defective TGF-beta type II receptor in mouse skeletal tissue promotes terminal chondrocyte differentiation and osteoarthritis. J. Cell Biol. 139 October (2) (1997) 541-552
    • (1997) J. Cell Biol. , vol.139 , Issue.October 2 , pp. 541-552
    • Serra, R.1    Johnson, M.2    Filvaroff, E.H.3    LaBorde, J.4    Sheehan, D.M.5    Derynck, R.6
  • 54
    • 0022452150 scopus 로고
    • Growth factor responsiveness declines during adulthood for human skin-derived cells
    • Stanulis-Praeger B.M., and Gilchrest B.A. Growth factor responsiveness declines during adulthood for human skin-derived cells. Mech. Ageing Dev. 35 July (2) (1986) 185-198
    • (1986) Mech. Ageing Dev. , vol.35 , Issue.July 2 , pp. 185-198
    • Stanulis-Praeger, B.M.1    Gilchrest, B.A.2
  • 56
    • 0033712592 scopus 로고    scopus 로고
    • Nitric oxide inhibits chondrocyte response to IGF-I: inhibition of IGF-IRbeta tyrosine phosphorylation
    • Studer R.K., Levicoff E., Georgescu H., Miller L., Jaffurs D., and Evans C.H. Nitric oxide inhibits chondrocyte response to IGF-I: inhibition of IGF-IRbeta tyrosine phosphorylation. Am. J. Physiol. Cell Physiol. 279 October (4) (2000) C961-C969
    • (2000) Am. J. Physiol. Cell Physiol. , vol.279 , Issue.October 4
    • Studer, R.K.1    Levicoff, E.2    Georgescu, H.3    Miller, L.4    Jaffurs, D.5    Evans, C.H.6
  • 57
    • 0031742193 scopus 로고    scopus 로고
    • Terminal differentiation of chondrocytes is arrested at distinct stages identified by their expression repertoire of marker genes
    • Szuts V., Mollers U., Bittner K., Schurmann G., Muratoglu S., Deak F., et al. Terminal differentiation of chondrocytes is arrested at distinct stages identified by their expression repertoire of marker genes. Matrix Biol. 17 October (6) (1998) 435-448
    • (1998) Matrix Biol. , vol.17 , Issue.October 6 , pp. 435-448
    • Szuts, V.1    Mollers, U.2    Bittner, K.3    Schurmann, G.4    Muratoglu, S.5    Deak, F.6
  • 58
    • 33846062161 scopus 로고    scopus 로고
    • A role for TGF-beta signaling in neurodegeneration: evidence from genetically engineered models
    • Tesseur I., and Wyss-Coray T. A role for TGF-beta signaling in neurodegeneration: evidence from genetically engineered models. Curr. Alzheimer Res. 3 December (5) (2006) 505-513
    • (2006) Curr. Alzheimer Res. , vol.3 , Issue.December 5 , pp. 505-513
    • Tesseur, I.1    Wyss-Coray, T.2
  • 59
    • 33750591957 scopus 로고    scopus 로고
    • Deficiency in neuronal TGF-beta signaling promotes neurodegeneration and Alzheimer's pathology
    • Tesseur I., Zou K., Esposito L., Bard F., Berber E., Can J.V., et al. Deficiency in neuronal TGF-beta signaling promotes neurodegeneration and Alzheimer's pathology. J. Clin. Invest. 116 November (11) (2006) 3060-3069
    • (2006) J. Clin. Invest. , vol.116 , Issue.November 11 , pp. 3060-3069
    • Tesseur, I.1    Zou, K.2    Esposito, L.3    Bard, F.4    Berber, E.5    Can, J.V.6
  • 60
    • 33746641679 scopus 로고    scopus 로고
    • Functional knockout of the matrilin-3 gene causes premature chondrocyte maturation to hypertrophy and increases bone mineral density and osteoarthritis
    • van der Weyden L., Wei L., Luo J., Yang X., Birk D.E., Adams D.J., et al. Functional knockout of the matrilin-3 gene causes premature chondrocyte maturation to hypertrophy and increases bone mineral density and osteoarthritis. Am. J. Pathol. 169 August (2) (2006) 515-527
    • (2006) Am. J. Pathol. , vol.169 , Issue.August 2 , pp. 515-527
    • van der Weyden, L.1    Wei, L.2    Luo, J.3    Yang, X.4    Birk, D.E.5    Adams, D.J.6
  • 62
    • 0023784221 scopus 로고
    • Osteoarthritis and obesity in the general population. A relationship calling for an explanation
    • van Saase J.L., Vandenbroucke J.P., van Romunde L.K., and Valkenburg H.A. Osteoarthritis and obesity in the general population. A relationship calling for an explanation. J. Rheumatol. 15 July (7) (1988) 1152-1158
    • (1988) J. Rheumatol. , vol.15 , Issue.July 7 , pp. 1152-1158
    • van Saase, J.L.1    Vandenbroucke, J.P.2    van Romunde, L.K.3    Valkenburg, H.A.4
  • 63
    • 0034750139 scopus 로고    scopus 로고
    • Age-related accumulation of the advanced glycation endproduct pentosidine in human articular cartilage aggrecan: the use of pentosidine levels as a quantitative measure of protein turnover
    • Verzijl N., DeGroot J., Bank R.A., Bayliss M.T., Bijlsma J.W., Lafeber F.P., et al. Age-related accumulation of the advanced glycation endproduct pentosidine in human articular cartilage aggrecan: the use of pentosidine levels as a quantitative measure of protein turnover. Matrix Biol. 20 November (7) (2001) 409-417
    • (2001) Matrix Biol. , vol.20 , Issue.November 7 , pp. 409-417
    • Verzijl, N.1    DeGroot, J.2    Bank, R.A.3    Bayliss, M.T.4    Bijlsma, J.W.5    Lafeber, F.P.6
  • 64
    • 10244219817 scopus 로고    scopus 로고
    • Regulation of MMP-13 expression by RUNX2 and FGF2 in osteoarthritic cartilage
    • Wang X., Manner P.A., Horner A., Shum L., Tuan R.S., and Nuckolls G.H. Regulation of MMP-13 expression by RUNX2 and FGF2 in osteoarthritic cartilage. Osteoarthritis Cartilage 12 December (12) (2004) 963-973
    • (2004) Osteoarthritis Cartilage , vol.12 , Issue.December 12 , pp. 963-973
    • Wang, X.1    Manner, P.A.2    Horner, A.3    Shum, L.4    Tuan, R.S.5    Nuckolls, G.H.6
  • 65
    • 0024416892 scopus 로고
    • Diet of the classical period of Greece and Rome
    • Waterlow J.C. Diet of the classical period of Greece and Rome. Eur. J. Clin. Nutr. 43 Suppl. 2 (1989) 3-12
    • (1989) Eur. J. Clin. Nutr. , vol.43 , Issue.SUPPL. 2 , pp. 3-12
    • Waterlow, J.C.1
  • 66
    • 33745603438 scopus 로고    scopus 로고
    • Tgf-Beta pathway as a potential target in neurodegeneration and Alzheimer's
    • Wyss-Coray T. Tgf-Beta pathway as a potential target in neurodegeneration and Alzheimer's. Curr. Alzheimer Res. 3 July (3) (2006) 191-195
    • (2006) Curr. Alzheimer Res. , vol.3 , Issue.July 3 , pp. 191-195
    • Wyss-Coray, T.1
  • 67
    • 0035795409 scopus 로고    scopus 로고
    • TGF-beta/Smad3 signals repress chondrocyte hypertrophic differentiation and are required for maintaining articular cartilage
    • Yang X., Chen L., Xu X., Li C., Huang C., and Deng C.X. TGF-beta/Smad3 signals repress chondrocyte hypertrophic differentiation and are required for maintaining articular cartilage. J. Cell. Biol. 153 April (1) (2001) 35-46
    • (2001) J. Cell. Biol. , vol.153 , Issue.April 1 , pp. 35-46
    • Yang, X.1    Chen, L.2    Xu, X.3    Li, C.4    Huang, C.5    Deng, C.X.6
  • 68
  • 69
    • 26444473434 scopus 로고    scopus 로고
    • Potential involvement of oxidative stress in cartilage senescence and development of osteoarthritis: oxidative stress induces chondrocyte telomere instability and downregulation of chondrocyte function
    • Yudoh K., Nguyen T., Nakamura H., Hongo-Masuko K., Kato T., and Nishioka K. Potential involvement of oxidative stress in cartilage senescence and development of osteoarthritis: oxidative stress induces chondrocyte telomere instability and downregulation of chondrocyte function. Arthritis Res. Ther. 7 2 (2005) R380-R391
    • (2005) Arthritis Res. Ther. , vol.7 , Issue.2
    • Yudoh, K.1    Nguyen, T.2    Nakamura, H.3    Hongo-Masuko, K.4    Kato, T.5    Nishioka, K.6
  • 70
    • 33746621756 scopus 로고    scopus 로고
    • Transcriptional profiling of aging in human muscle reveals a common aging signature
    • Zahn J.M., Sonu R., Vogel H., Crane E., Mazan-Mamczarz K., Rabkin R., et al. Transcriptional profiling of aging in human muscle reveals a common aging signature. PLoS Genet 2 July (7) (2006) e115
    • (2006) PLoS Genet , vol.2 , Issue.July 7
    • Zahn, J.M.1    Sonu, R.2    Vogel, H.3    Crane, E.4    Mazan-Mamczarz, K.5    Rabkin, R.6
  • 71
    • 33750313169 scopus 로고    scopus 로고
    • Reduction of leucocyte telomere length in radiographic hand osteoarthritis: a population-based study
    • Zhai G., Aviv A., Hunter D.J., Hart D.J., Gardner J.P., Kimura M., et al. Reduction of leucocyte telomere length in radiographic hand osteoarthritis: a population-based study. Ann. Rheum. Dis. 65 November (11) (2006) 1444-1448
    • (2006) Ann. Rheum. Dis. , vol.65 , Issue.November 11 , pp. 1444-1448
    • Zhai, G.1    Aviv, A.2    Hunter, D.J.3    Hart, D.J.4    Gardner, J.P.5    Kimura, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.