Osteoarthritis in the context of ageing and evolution. Loss of chondrocyte differentiation block during ageing

Ageing Research Reviews

Volumn 7, Issue 2, 2008, Pages 106-113

  van der Kraan, Peter M ^a   van den Berg, Wim B ^a  

^a RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

Author keywords

Cartilage; Chondrocytes; Osteoarthritis; Terminal differentiation

Indexed keywords

GROWTH FACTOR; REACTIVE OXYGEN METABOLITE; TRANSFORMING GROWTH FACTOR BETA;

AGING; APOPTOSIS; ARTICULAR CARTILAGE; CARTILAGE CELL; CARTILAGE DEGENERATION; CARTILAGE MATRIX; CELL DIFFERENTIATION; CELL LOSS; ENERGY RESOURCE; GENE MUTATION; HUMAN; INBORN ERROR OF METABOLISM; MOLECULAR EVOLUTION; NONHUMAN; OSTEOARTHRITIS; OXIDATIVE STRESS; PROTEIN DEPLETION; PROTEIN FUNCTION; REPRODUCTION; SENESCENCE; SHORT SURVEY; SIGNAL TRANSDUCTION;

ADENOSINE TRIPHOSPHATE; AGING; ANIMALS; APOPTOSIS; CELL DIFFERENTIATION; CHONDROCYTES; EVOLUTION; HUMANS; OSTEOARTHRITIS;

ANIMALIA;

EID: 41049117461     PISSN: 15681637     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.arr.2007.10.001     Document Type: Short Survey

References (71)

1. Acosta C.A., Izal I., Ripalda P., Douglas-Price A.L., and Forriol F. Gene expression and proliferation analysis in young, aged, and osteoarthritic sheep chondrocytes effect of growth factor treatment. J. Orthop. Res. 24 November (11) (2006) 2087-2094
2. Aigner T., and Kim H.A. Apoptosis and cellular vitality: issues in osteoarthritic cartilage degeneration. Arthritis Rheum. 46 August (8) (2002) 1986-1996
3. Aigner T., Kurz B., Fukui N., and Sandell L. Roles of chondrocytes in the pathogenesis of osteoarthritis. Curr. Opin. Rheumatol. 14 September (5) (2002) 578-584
4. Aigner T., Rose J., Martin J., and Buckwalter J. Aging theories of primary osteoarthritis: from epidemiology to molecular biology. Rejuvenation Res. 7 2 (2004) 134-145
5. Bank R.A., Bayliss M.T., Lafeber F.P., Maroudas A., and TeKoppele J.M. Ageing and zonal variation in post-translational modification of collagen in normal human articular cartilage. The age-related increase in non-enzymatic glycation affects biomechanical properties of cartilage. Biochem. J. 330 Feb (Pt 1) (1998) 345-351
6. Bihari-Varga M., Farkas T., and Biro T. Changes in the cartilage proteoglycans in relation to age and osteoarthrosis. Acta Biol. Hung. 35 2-4 (1984) 325-331
7. Blanco F.J., Guitian R., Vazquez-Martul E., de Toro F.J., and Galdo F. Osteoarthritis chondrocytes die by apoptosis. A possible pathway for osteoarthritis pathology. Arthritis Rheum. 41 Feb (2) (1998) 284-289
8. Blaney Davidson E.N., Scharstuhl A., Vitters E.L., van der Kraan P.M., and van den Berg W.B. Reduced transforming growth factor-beta signaling in cartilage of old mice: role in impaired repair capacity. Arthritis Res. Ther. 7 6 (2005) R1338-R1347
9. Bomsta B.D., Bridgewater L.C., and Seegmiller R.E. Premature osteoarthritis in the Disproportionate micromelia (Dmm) mouse. Osteoarthritis Cartilage 14 May (5) (2006) 477-485
10. Buckwalter J.A., and Mankin H.J. Articular cartilage: degeneration and osteoarthritis, repair, regeneration, and transplantation. Instr. Course Lect. 47 (1998) 487-504
11. Corstjens H., Declercq L., Hellemans L., Sente I., and Maes D. Prevention of oxidative damage that contributes to the loss of bioenergetic capacity in ageing skin. Exp. Gerontol. 42 september 9 (2007) 924-929
12. Dabovic B., Chen Y., Colarossi C., Obata H., Zambuto L., Perle M.A., et al. Bone abnormalities in latent TGF-[beta] binding protein (Ltbp)-3-null mice indicate a role for Ltbp-3 in modulating TGF-[beta] bioavailability. J. Cell Biol. 156 January (2) (2002) 227-232
13. Das P., and Golde T. Dysfunction of TGF-beta signaling in Alzheimer's disease. J. Clin. Invest. 116 November (11) (2006) 2855-2857
14. DeGroot J. The AGE of the matrix: chemistry, consequence and cure. Curr. Opin. Pharmacol. 4 June (3) (2004) 301-305
15. DeGroot J., Verzijl N., Jacobs K.M., Budde M., Bank R.A., Bijlsma J.W., et al. Accumulation of advanced glycation endproducts reduces chondrocyte-mediated extracellular matrix turnover in human articular cartilage. Osteoarthritis Cartilage 9 November (8) (2001) 720-726
16. DeGroot J., Verzijl N., Wenting-van Wijk M.J., Jacobs K.M., Van E.B., Van Roermund P.M., et al. Accumulation of advanced glycation end products as a molecular mechanism for aging as a risk factor in osteoarthritis. Arthritis Rheum. 50 April (4) (2004) 1207-1215
17. Forsyth C.B., Cole A., Murphy G., Bienias J.L., Im H.J., and Loeser Jr. R.F. Increased matrix metalloproteinase-13 production with aging by human articular chondrocytes in response to catabolic stimuli. J. Gerontol. A Biol. Sci. Med. Sci. 60 September (9) (2005) 1118-1124
18. Fortier L.A., and Miller B.J. Signaling through the small G-protein Cdc42 is involved in insulin-like growth factor-I resistance in aging articular chondrocytes. J. Orthop. Res. 24 August (8) (2006) 1765-1772
19. Guerne P.A., Blanco F., Kaelin A., Desgeorges A., and Lotz M. Growth factor responsiveness of human articular chondrocytes in aging and development. Arthritis Rheum. 38 July (7) (1995) 960-968
20. Harcourt R.A. The palaeopathology of animal skeletal remains. Vet. Rec. 89 September (10) (1971) 267-272
21. Hashimoto S., Ochs R.L., Komiya S., and Lotz M. Linkage of chondrocyte apoptosis and cartilage degradation in human osteoarthritis. Arthritis Rheum. 41 September (9) (1998) 1632-1638
22. Henrotin Y., Kurz B., and Aigner T. Oxygen and reactive oxygen species in cartilage degradation: friends or foes?. Osteoarthritis Cartilage 13 August (8) (2005) 643-654
23. Horton A.A., and Spencer J.A. Decline in respiratory control ratio of rat liver mitochondria in old age. Mech. Ageing Dev. 17 November (3) (1981) 253-259
24. Ijiri K., Zerbini L.F., Peng H., Correa R.G., Lu B., Walsh N., et al. A novel role for GADD45beta as a mediator of MMP-13 gene expression during chondrocyte terminal differentiation. J. Biol. Chem. 280 November (46) (2005) 38544-38555
25. Inada M., Wang Y., Byrne M.H., Rahman M.U., Miyaura C., Lopez-Otin C., et al. Critical roles for collagenase-3 (Mmp13) in development of growth plate cartilage and in endochondral ossification. Proc. Natl. Acad. Sci. U.S.A. 101 December (49) (2004) 17192-17197
26. Johnson K., Jung A., Murphy A., Andreyev A., Dykens J., and Terkeltaub R. Mitochondrial oxidative phosphorylation is a downstream regulator of nitric oxide effects on chondrocyte matrix synthesis and mineralization. Arthritis Rheum. 43 July (7) (2000) 1560-1570
27. Johnson K., Svensson C.I., Etten D.V., Ghosh S.S., Murphy A.N., Powell H.C., et al. Mediation of spontaneous knee osteoarthritis by progressive chondrocyte ATP depletion in Hartley guinea pigs. Arthritis Rheum. 50 April (4) (2004) 1216-1225
28. Kerin A., Patwari P., Kuettner K., Cole A., and Grodzinsky A. Molecular basis of osteoarthritis: biomechanical aspects. Cell Mol. Life Sci. 59 January (1) (2002) 27-35
29. Kessler M.J., Turnquist J.E., Pritzker K.P., and London W.T. Reduction of passive extension and radiographic evidence of degenerative knee joint diseases in cage-raised and free-ranging aged rhesus monkeys (Macaca mulatta). J. Med. Primatol. 15 1 (1986) 1-9
30. Kim H.A., Lee Y.J., Seong S.C., Choe K.W., and Song Y.W. Apoptotic chondrocyte death in human osteoarthritis. J. Rheumatol. 27 February (2) (2000) 455-462
31. Lark M.W., Bayne E.K., Flanagan J., Harper C.F., Hoerrner L.A., Hutchinson N.I., et al. Aggrecan degradation in human cartilage. Evidence for both matrix metalloproteinase and aggrecanase activity in normal, osteoarthritic, and rheumatoid joints. J. Clin. Invest. 100 July (1) (1997) 93-106
32. Li T.F., Darowish M., Zuscik M.J., Chen D., Schwarz E.M., Rosier R.N., et al. Smad3-deficient chondrocytes have enhanced BMP signaling and accelerated differentiation. J. Bone Miner. Res. 21 January (1) (2006) 4-16
33. Lin Y., Luo E., Chen X., Liu L., Qiao J., Yan Z., et al. Molecular and cellular characterization during chondrogenic differentiation of adipose tissue-derived stromal cells in vitro and cartilage formation in vivo. J.Cell Mol. Med. 9 October (4) (2005) 929-939
34. Loeser R.F., Shanker G., Carlson C.S., Gardin J.F., Shelton B.J., and Sonntag W.E. Reduction in the chondrocyte response to insulin-like growth factor 1 in aging and osteoarthritis: studies in a non-human primate model of naturally occurring disease. Arthritis Rheum. 43 September (9) (2000) 2110-2120
35. Loeser R.F., Carlson C.S., Del C.M., and Cole A. Detection of nitrotyrosine in aging and osteoarthritic cartilage: Correlation of oxidative damage with the presence of interleukin-1beta and with chondrocyte resistance to insulin-like growth factor 1. Arthritis Rheum. 46 September (9) (2002) 2349-2357
36. Loeser R.F., Yammani R.R., Carlson C.S., Chen H., Cole A., Im H.J., et al. Articular chondrocytes express the receptor for advanced glycation end products: Potential role in osteoarthritis. Arthritis Rheum. 52 August (8) (2005) 2376-2385
37. Lotz M., Hashimoto S., and Kuhn K. Mechanisms of chondrocyte apoptosis. Osteoarthritis Cartilage 7 July (4) (1999) 389-391
38. Luo J., Lin A.H., Masliah E., and Wyss-Coray T. Bioluminescence imaging of Smad signaling in living mice shows correlation with excitotoxic neurodegeneration. Proc. Natl. Acad. Sci. U.S.A. 103 November (48) (2006) 18326-18331
39. Marmor D. The arthritides, a medicolegal review. Osteoarthritis (degenerative, hypertrophic, senescent, or "wear and tear" arthritis). Med. Trial Tech. Q 15 March (3) (1969) 37-58
40. Martin J.A., and Buckwalter J.A. The role of chondrocyte senescence in the pathogenesis of osteoarthritis and in limiting cartilage repair. J. Bone Joint Surg. Am. 85-A Suppl. 2 (2003) 106-110
41. Martin J.A., and Buckwalter J.A. Aging articular cartilage chondrocyte senescence and osteoarthritis. Biogerontology 3 5 (2002) 257-264
42. Martin J.A., Klingelhutz A.J., Moussavi-Harami F., and Buckwalter J.A. Effects of oxidative damage and telomerase activity on human articular cartilage chondrocyte senescence. J. Gerontol. A Biol. Sci. Med. Sci. 59 April (4) (2004) 324-337
43. Mitchell P.G., Magna H.A., Reeves L.M., Lopresti-Morrow L.L., Yocum S.A., Rosner P.J., et al. Cloning, expression, and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilage. J. Clin. Invest. 97 February (3) (1996) 761-768
44. Moldovan F., Pelletier J.P., Hambor J., Cloutier J.M., and Martel-Pelletier J. Collagenase-3 (matrix metalloprotease 13) is preferentially localized in the deep layer of human arthritic cartilage in situ: in vitro mimicking effect by transforming growth factor beta. Arthritis Rheum. 40 September (9) (1997) 1653-1661
45. Olsen B.R. Mutations in collagen genes resulting in metaphyseal and epiphyseal dysplasias. Bone 17 August (2 Suppl.) (1995) 45S-49S
46. Pacifici M., Golden E.B., Oshima O., Shapiro I.M., Leboy P.S., and Adams S.L. Hypertrophic chondrocytes. The terminal stage of differentiation in the chondrogenic cell lineage?. Ann. N.Y. Acad. Sci. 599 (1990) 45-57
47. Phelan J.P., and Austad S.N. Natural selection, dietary restriction, and extended longevity. Growth Dev. Aging 53 1-2 (1989) 4-6
48. Poliard A., Ronziere M.C., Freyria A.M., Lamblin D., Herbage D., and Kellermann O. Lineage-dependent collagen expression and assembly during osteogenic or chondrogenic differentiation of a mesoblastic cell line. Exp. Cell Res. 253 December (2) (1999) 385-395
49. Rothschild B.M., and Panza R. Osteoarthritis is for the birds. Clin. Rheumatol. 25 September (5) (2006) 645-647
50. Sahebjam S., Khokha R., and Mort J.S. Increased collagen and aggrecan degradation with age in the joints of Timp3(-/-) mice. Arthritis Rheum. 56 Mar (3) (2007) 905-909
51. Scharstuhl A., van Beuningen H.M., Vitters E.L., van der Kraan P.M., and van den Berg W.B. Loss of transforming growth factor counteraction on interleukin 1 mediated effects in cartilage of old mice. Ann. Rheum. Dis. 61 December (12) (2002) 1095-1098
52. Serra R., Johnson M., Filvaroff E.H., LaBorde J., Sheehan D.M., Derynck R., et al. Expression of a truncated, kinase-defective TGF-beta type II receptor in mouse skeletal tissue promotes terminal chondrocyte differentiation and osteoarthritis. J. Cell Biol. 139 October (2) (1997) 541-552
53. Shlopov B.V., Lie W.R., Mainardi C.L., Cole A.A., Chubinskaya S., and Hasty K.A. Osteoarthritic lesions: involvement of three different collagenases. Arthritis Rheum. 40 November (11) (1997) 2065-2074
54. Stanulis-Praeger B.M., and Gilchrest B.A. Growth factor responsiveness declines during adulthood for human skin-derived cells. Mech. Ageing Dev. 35 July (2) (1986) 185-198
55. Studer R., Jaffurs D., Stefanovic-Racic M., Robbins P.D., and Evans C.H. Nitric oxide in osteoarthritis. Osteoarthritis Cartilage 7 July4) (1999) 377-379
56. Studer R.K., Levicoff E., Georgescu H., Miller L., Jaffurs D., and Evans C.H. Nitric oxide inhibits chondrocyte response to IGF-I: inhibition of IGF-IRbeta tyrosine phosphorylation. Am. J. Physiol. Cell Physiol. 279 October (4) (2000) C961-C969
57. Szuts V., Mollers U., Bittner K., Schurmann G., Muratoglu S., Deak F., et al. Terminal differentiation of chondrocytes is arrested at distinct stages identified by their expression repertoire of marker genes. Matrix Biol. 17 October (6) (1998) 435-448
58. Tesseur I., and Wyss-Coray T. A role for TGF-beta signaling in neurodegeneration: evidence from genetically engineered models. Curr. Alzheimer Res. 3 December (5) (2006) 505-513
59. Tesseur I., Zou K., Esposito L., Bard F., Berber E., Can J.V., et al. Deficiency in neuronal TGF-beta signaling promotes neurodegeneration and Alzheimer's pathology. J. Clin. Invest. 116 November (11) (2006) 3060-3069
60. van der Weyden L., Wei L., Luo J., Yang X., Birk D.E., Adams D.J., et al. Functional knockout of the matrilin-3 gene causes premature chondrocyte maturation to hypertrophy and increases bone mineral density and osteoarthritis. Am. J. Pathol. 169 August (2) (2006) 515-527
61. van der Kraan P.M., and van den Berg W.B. Osteophytes: relevance and biology. Osteoarthritis Cartilage 15 Mar (3) (2007) 237-244
62. van Saase J.L., Vandenbroucke J.P., van Romunde L.K., and Valkenburg H.A. Osteoarthritis and obesity in the general population. A relationship calling for an explanation. J. Rheumatol. 15 July (7) (1988) 1152-1158
63. Verzijl N., DeGroot J., Bank R.A., Bayliss M.T., Bijlsma J.W., Lafeber F.P., et al. Age-related accumulation of the advanced glycation endproduct pentosidine in human articular cartilage aggrecan: the use of pentosidine levels as a quantitative measure of protein turnover. Matrix Biol. 20 November (7) (2001) 409-417
64. Wang X., Manner P.A., Horner A., Shum L., Tuan R.S., and Nuckolls G.H. Regulation of MMP-13 expression by RUNX2 and FGF2 in osteoarthritic cartilage. Osteoarthritis Cartilage 12 December (12) (2004) 963-973
65. Waterlow J.C. Diet of the classical period of Greece and Rome. Eur. J. Clin. Nutr. 43 Suppl. 2 (1989) 3-12
66. Wyss-Coray T. Tgf-Beta pathway as a potential target in neurodegeneration and Alzheimer's. Curr. Alzheimer Res. 3 July (3) (2006) 191-195
67. Yang X., Chen L., Xu X., Li C., Huang C., and Deng C.X. TGF-beta/Smad3 signals repress chondrocyte hypertrophic differentiation and are required for maintaining articular cartilage. J. Cell. Biol. 153 April (1) (2001) 35-46
68. Yoo J.U., Barthel T.S., Nishimura K., Solchaga L., Caplan A.I., Goldberg V.M., et al. The chondrogenic potential of human bone-marrow-derived mesenchymal progenitor cells. J. Bone Joint Surg. Am. 80 December (12) (1998) 1745-1757
69. Yudoh K., Nguyen T., Nakamura H., Hongo-Masuko K., Kato T., and Nishioka K. Potential involvement of oxidative stress in cartilage senescence and development of osteoarthritis: oxidative stress induces chondrocyte telomere instability and downregulation of chondrocyte function. Arthritis Res. Ther. 7 2 (2005) R380-R391
70. Zahn J.M., Sonu R., Vogel H., Crane E., Mazan-Mamczarz K., Rabkin R., et al. Transcriptional profiling of aging in human muscle reveals a common aging signature. PLoS Genet 2 July (7) (2006) e115
71. Zhai G., Aviv A., Hunter D.J., Hart D.J., Gardner J.P., Kimura M., et al. Reduction of leucocyte telomere length in radiographic hand osteoarthritis: a population-based study. Ann. Rheum. Dis. 65 November (11) (2006) 1444-1448