Egr1 and Gas6 facilitate the adaptation of HEK-293 cells to serum-free media by conferring enhanced viability and higher growth rates

Biotechnology and Bioengineering

Volumn 99, Issue 6, 2008, Pages 1443-1452

  Jaluria, Pratik ^a,b   Konstantopoulos, Konstantinos ^b   Betenbaugh, Michael ^b   Shiloach, Joseph ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b Johns Hopkins University   (United States)

Author keywords

Adaptation; Early growth response 1; Growth arrest specific 6; Microarrays; Serum free media; Survivability

Indexed keywords

CELL CULTURE; GENE EXPRESSION; MICROARRAYS; OLIGONUCLEOTIDES; PHYSIOLOGICAL MODELS;

GROWTH ARREST SPECIFIC 6; SERUM-FREE MEDIA; SURVIVABILITY;

CELL GROWTH;

CASPASE; EARLY GROWTH RESPONSE FACTOR 1; GROWTH ARREST SPECIFIC PROTEIN 6; EGR1 PROTEIN, HUMAN; GAS6 PROTEIN, MOUSE; SIGNAL PEPTIDE; UNCLASSIFIED DRUG;

ADAPTATION; ARTICLE; CELL CYCLE PROGRESSION; CELL GROWTH; CELL VIABILITY; CONTROLLED STUDY; COW; CULTURE MEDIUM; DNA MICROARRAY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; HUMAN; HUMAN CELL; MICROARRAY ANALYSIS; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; CYTOLOGY; GENETIC ENHANCEMENT; GENETICS; KIDNEY; METABOLISM; METHODOLOGY; PHYSIOLOGY; PROTEIN ENGINEERING;

ANIMALIA; BOVINAE; MAMMALIA;

ADAPTATION, PHYSIOLOGICAL; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; CULTURE MEDIA, SERUM-FREE; EARLY GROWTH RESPONSE PROTEIN 1; GENETIC ENHANCEMENT; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; KIDNEY; PROTEIN ENGINEERING;

EID: 41049088525     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.21707     Document Type: Article

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