Activation of dopamine D1-like receptors in nucleus accumbens is critical for the acquisition, but not the expression, of nutrient-conditioned flavor preferences in rats

European Journal of Neuroscience

Volumn 27, Issue 6, 2008, Pages 1525-1533

  Touzani, Khalid ^a   Bodnar, Richard ^b   Sclafani, Anthony ^a,b  

^a CITY UNIVERSITY OF NEW YORK   (United States)

^b CITY UNIVERSITY OF NEW YORK   (United States)

Author keywords

Carbohydrate; Conditioning; Core; SCH23390; Shell

Indexed keywords

8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; CARBOHYDRATE; DOPAMINE 1 RECEPTOR; DOPAMINE D1 LIKE RECEPTOR; GLUCOSE; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CATHETER; CONDITIONING; CONTROLLED STUDY; DOPAMINERGIC TRANSMISSION; FLAVOR; FLUID INTAKE; LEARNING; MALE; NONHUMAN; NUCLEUS ACCUMBENS; NUTRIENT; PRIORITY JOURNAL; RAT; TASTE PREFERENCE;

ANIMALS; CONDITIONING (PSYCHOLOGY); FOOD PREFERENCES; MALE; NUCLEUS ACCUMBENS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE D1; SWEETENING AGENTS; TASTE;

EID: 40949107371     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2008.06127.x     Document Type: Article

References (56)

1. Ågmo, A., Galvan, A. Talamantes, B. (1995) Reward and reinforcement produced by drinking sucrose: Two processes that may depend on different neurotransmitters. Pharmacol. Biochem. Behav., 52, 403 414.
2. Ahn, S. Phillips, A.G. (2007) Dopamine efflux in the nucleus accumbens during within-session extinction, outcome-dependent, and habit-based instrumental responding for food reward. Psychopharmacology, 191, 641 651.
3. Bernal, S.Y., Miner, P., Abayev, Y., Kandova, E., Pulatov, P, Touzani, K., Sclafani, A. Bodnar, R.J. (2007) Aquisition of fructose-conditioned flavor preferences in rats: role of D1 and D2 dopamine receptors in the nucleus accumbens and amygdala. Soc. Neurosci. Abstr., 629.2.
4. 2 dopamine receptor antagonism blocks the acquisition of a flavor preference conditioned by intragastric carbohydrate infusions. Pharmacol. Biochem. Behav., 68, 709 720.
5. Baker, R.M., Shah, M.J., Sclafani, A. Bodnar, R.J. (2003) Dopamine D1 and D2 antagonists reduce the acquisition and expression of flavor-preferences conditioned by fructose in rats. Pharmacol. Biochem. Behav., 75, 55 65.
6. Baldo, B.A. Kelley, A.E. (2007) Discrete neurochemical coding of distinguishable motivational processes: insights from nucleus accumbens control of feeding. Psychopharmacology, 191, 439 459.
7. Baldo, B.A., Sadeghian, K., Basso, A.M. Kelley, A.E. (2002) Effects of selective dopamine D1 or D2 receptor blockade within nucleus accumbens subregions on ingestive behavior and associated motor activity. Behav. Brain Res., 137, 165 177.
8. Baldwin, A.E., Sadeghian, K., Holahan, M.R. Kelley, A.E. (2002a) Appetitive instrumental learning is impaired by inhibition of cAMP-dependent protein kinase within the nucleus accumbens. Neurobiol. Learn. Mem., 77, 44 62.
9. Baldwin, A.E., Sadeghian, K. Kelley, A.E. (2002b) Appetitive instrumental learning requires coincident activation of NMDA and dopamine D1 receptors within the medial prefrontal cortex. J. Neurosci., 22, 1063 1071.
10. Barbano, M.F. Cador, M. (2007) Opioids for hedonic experience and dopamine to get ready for it. Psychopharmacology, 191, 497 506.
11. Bari, A.A. Pierce, R.C. (2005) D1-like and D2 dopamine receptor antagonists administered into the shell subregion of the rat nucleus accumbens decrease cocaine, but not food, reinforcement. Neuroscience, 135, 959 968.
12. Bassareo, V., De Luca, M.A. Di Chiara, G. (2002) Differential expression of motivational stimulus properties by dopamine in nucleus accumbens shell versus core and prefrontal cortex. J. Neurosci., 22, 4709 4719.
13. Beninger, R.J. Miller, R. (1998) Dopamine D1-like receptors and reward-related incentive learning. Neurosci. Biobehav. Rev., 22, 335 345.
14. Berridge, K.C. (2007) The debate over dopamine's role in reward: the case for incentive salience. Psychopharmacology, 191, 391 431.
15. Berridge, K.C. Robinson, T.E. (1998) What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience? Brain Res. Rev., 28, 309 369.
16. Bures, J., Bermúdez-Rattoni, F. Yamamoto, T. (1998) Conditioned Taste Aversion: Memory of a Special Kind. Oxford University Press, Oxford.
17. Cannon, C.M. Bseikri, M.R. (2004) Is dopamine required for natural reward? Physiol. Behav., 81, 741 748.
18. Cannon, C.M. Palmiter, R.D. (2003) Reward without dopamine. J. Neurosci., 23, 10827 10831.
19. Capaldi, E.D. (1996) Conditioned food preferences. In Capaldi, E.D. (ed.), Why We Eat What We Eat: the Psychology of Eating. American Psychological Association, Washington, DC, pp. 53 80.
20. Caulliez, R., Meile, M.-J. Nicolaidis, S. (1996) A lateral hypothalamic D1 dopaminergic mechanism in conditioned taste aversion. Brain Res., 729, 234 245.
21. Cheng, J.J., de Bruin, J.P.C. Feenstra, M.G.P. (2003) Dopamine efflux in nucleus accumbens shell and core in response to appetitive classical conditioning. Eur. J. Neurosci., 18, 1306 1314.
22. Costa, R.M., Gutierrez, R., De Araujo, I.E., Coelho, M.R.P., Kloth, A.D., Gainetdinov, R.R., Caron, M.G., Nicolelis, M.A.L. Simon, S.A. (2006) Dopamine levels modulate the updating of tastant values. Genes Brain Behav., 6, 314 320.
23. Di Chiara, G. Bassareo, V. (2007) Reward system and addiction: what dopamine does and doesn't do. Curr. Opin. Pharmacol., 7, 69 76.
24. Di Ciano, P., Cardinal, R.N., Cowell, R.A., Little, S.J. Everitt, B.J. (2001) Differential involvement of NMDA, AMPA/kainate, and dopamine receptors in the nucleus accumbens core in the acquisition and performance of Pavlovian approach behavior. J. Neurosci., 21, 9471 9477.
25. Fenu, S., Bassareo, V. Di Chiara, G. (2001) A role for dopamine D1 receptors of the nucleus accumbens shell in conditioned taste aversion learning. J. Neurosci., 21, 6897 6904.
26. Fenu, S., Spina, L., Rivas, E., Longoni, R. Di Chiara, G. (2006) Morphine-conditioned single-trial place preference: role of nucleus accumbens shell dopamine receptors in acquisition, but not expression. Psychopharmacology (Berl.), 187, 143 153.
27. Geary, N. Smith, G.P. (1985) Pimozide decreases the positive reinforcing effects of sham fed sucrose in the rat. Pharmacol. Biochem. Behav., 22, 787 790.
28. Hajnal, A., Smith, G.P. Norgren, R. (2003) Oral sucrose stimulation increases accumbens dopamine in the rat. Am. J. Physiol., 286, R31 R37.
29. Horvitz, J.C., Choi, W.Y., Morvan, C., Eyny, Y. Balsam, P.D. (2007) A 'Good Parent' function of dopamine. Transient modulation of learning and performance during early stages of training. Ann. NY Acad. Sci., 1104, 270 288.
30. Huang, A.C.W. Hsiao, S. (2002) Haloperidol attenuates rewarding and aversively conditioned suppression of saccharin solution intake: Reevaluation of the anhedonia hypothesis of dopamine blocking. Behav. Neurosci., 116, 646 650.
31. Ikemoto, S. (2007) Dopamine reward circuitry: Two projection systems from the ventral midbrain to the nucleus accumbens-olfactory tubercle complex. Brain Res. Rev., 56, 27 78.
32. Ikemoto, S. Panksepp, J. (1999) The role of nucleus accumbens dopamine in motivated behavior: a unifying interpretation with special reference to reward-seeking. Brain. Res. Rev., 31, 6 41.
33. Imaizumi, M., Takeda, M. Fushiki, T. (2000) Effects of oil intake in the conditioned place preference test in mice. Brain Res., 870, 150 156.
34. Kandel, E.R. (2001) The molecular biology of memory storage: a dialog between genes and synapses. Science, 294, 1030 1038.
35. Kirk, R.E. (1995) Experimental Design: Procedures for the Behavioral Sciences. Brooks/Cole, Pacific Grove, CA.
36. Liang, N.C., Hajnal, A. Norgren, R. (2006) Sham feeding corn oil increases accumbens dopamine in the rat. Am. J. Physiol. Regul. Integr. Comp. Physiol., 291, R1236 R1239.
37. Mark, G.P., Smith, S.E., Rada, P.V. Hoebel, B.G. (1994) An appetitively conditioned taste elicits a preferential increase in mesolimbic dopamine release. Pharmacol. Biochem. Behav., 48, 651 660.
38. Myers, K.P. Sclafani, A. (2001) Conditioned enhancement of flavor evaluation reinforced by intragastric glucose. II. Taste reactivity analysis. Physiol. Behav., 74, 495 505.
39. Nowend, K.L., Arizzi, M., Carlson, B.B. Salamone, J.D. (2001) D1 or D2 antagonism in nucleus accumbens core or dorsomedial shell suppresses lever pressing for food but leads to compensatory increases in chow consumption. Pharmacol. Biochem. Behav., 69, 373 382.
40. Paxinos, G. Watson, C. (1998) The Rat Brain in Stereotaxic Coordinates. Academic Press, San Diego, CA.
41. Ramirez-Lugo, L., Nunez-Jaramillo, L. Bermudez-Rattoni, F. (2007) Taste memory formation: Role of nucleus accumbens. Chem. Senses, 32, 93 97.
42. Sclafani, A. (1999) Macronutrient-conditioned flavor preferences. In Berthoud, H.-R. Seeley, R. (eds), Neural and Metabolic Control of Macronutrient Intake. CRC Press, Boca Raton, FL, pp. 93 107.
43. Sclafani, A. Ackroff, K. (2006) Nutrient-conditioned flavor preference and incentive value measured by progressive ratio licking in rats. Physiol. Behav., 88, 88 94.
44. Sclafani, A., Azzara, A.V., Touzani, K., Grigson, P.S. Norgren, R. (2001) Parabrachial nucleus lesions block taste and attenuate flavor preference and aversion conditioning in rats. Behav. Neurosci., 115, 920 933.
45. Sclafani, A., Fanizza, L.J. Azzara, A.V. (1999) Conditioned flavor avoidance, preference and indifference produced by intragastric infusions of galactose, glucose and fructose in rats. Physiol. Behav., 67, 227 234.
46. Smith, G.P. (1995) Dopamine and food reward. In Fluharty, S. Morrison, A.M. (eds), Progress in Psychobiology and Physiological Psychology, Vol. 16. Academic Press, New York, pp. 83 144.
47. Smith-Roe, S.L. Kelley, A.E. (2000) Coincident activation of NMDA and dopamine D1 receptors within the nucleus accumbens core is required for appetitive instrumental learning. J. Neurosci., 20, 7737 7742.
48. Spina, L., Fenu, S., Longoni, R., Rivas, E. Di Chiara, G. (2006) Nicotine-conditioned single-trial place preference: selective role of nucleus accumbens shell dopamine D1 receptors in acquisition. Psychopharmacology, 184, 447 455.
49. Sutton, M.A. Beninger, R.J. (1999) Psychopharmacology of conditioned reward: evidence for a rewarding signal at D1-like dopamine receptors. Psychopharmacology, 144, 95 110.
50. Szczypka, M.S., Kwok, K., Brot, M.D., Marck, B.T., Matsumoto, A.M., Donahue, B.A. Palmiter, R.D. (2001) Dopamine production in the caudate putamen restores feeding in dopamine-deficient mice. Neuron, 30, 819 828.
51. Touzani, K. Sclafani, A. (2001) Conditioned flavor preference and aversion: Role of the lateral hypothalamus. Behav. Neurosci., 115, 84 93.
52. Touzani, K. Sclafani, A. (2002) Lateral hypothalamic lesions impair flavor-nutrient and flavor-toxin trace learning in rats. Eur. J. Neurosci., 16, 2425 2433.
53. Touzani, K. Sclafani, A. (2005) Critical role of amygdala in flavor but not taste preference learning in rats. Eur. J. Neurosci., 22, 1767 1774.
54. Weatherford, S.C., Greenberg, D., Gibbs, J. Smith, G.P. (1990) The potency of D-1 and D-2 receptor antagonists is inversely related to the reward value of sham-fed corn oil and sucrose in rats. Pharmacol. Biochem. Behav., 37, 317 323.
55. Wise, R.A. (2004) Dopamine, learning and motivation. Nat. Rev. Neurosci., 5, 483 494.
56. Yiin, Y.-M., Ackroff, K. Sclafani, A. (2005) Flavor preferences conditioned by intragastric nutrient infusions in food restricted and unrestricted rats. Physiol. Behav., 84, 217 231.