Crystal structure of a novel myotoxic Arg49 phospholipase A2 homolog (zhaoermiatoxin) from Zhaoermia mangshanensis snake venom: Insights into Arg49 coordination and the role of Lys122 in the polarization of the C-terminus

Toxicon

Volumn 51, Issue 5, 2008, Pages 723-735

  Murakami, Mário T ^a   Kuch, Ulrich ^b   Betzel, Christian ^c   Mebs, Dietrich ^b   Arni, Raghuvir K ^a,d  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^c UNIVERSITY OF HAMBURG   (Germany)

^d CAT CEPID   (Brazil)

Author keywords

Arg49 phospholipase A2; Crystal structure; Lys49 phospholipase A2; Myotoxin; Snake venom; Zhaoermia mangshanensis

Indexed keywords

CARBONYL DERIVATIVE; GUANIDINE; OXYGEN; PHOSPHOLIPASE A2; SNAKE VENOM; UNCLASSIFIED DRUG; ZHAOERMIATOXIN;

AMINO ACID SUBSTITUTION; ARTICLE; ATOM; CALCIUM BINDING; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; NONHUMAN; POLARIZATION; PRIORITY JOURNAL; SNAKE;

AMINO ACID SEQUENCE; ANIMALS; ANIONS; CALCIUM; CROTALID VENOMS; CRYSTALLOGRAPHY, X-RAY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHOSPHOLIPASES A2; POLYETHYLENE GLYCOLS; PROTEIN BINDING; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT; VIPERIDAE;

TETRA; ZHAOERMIA MANGSHANENSIS;

EID: 40849126458     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2007.11.018     Document Type: Article

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