Inflammatory events induced by Lys-49 and Asp-49 phospholipases A 2 isolated from Bothrops asper snake venom: Role of catalytic activity

Toxicon

Volumn 45, Issue 3, 2005, Pages 335-346

  Zuliani, Juliana P ^a   Fernandes, Cristina M ^a   Zamuner, Stella R ^a   Gutiérrez, José M ^b   Teixeira, Catarina F P ^a  

^a INSTITUTO BUTANTAN   (Brazil)

^b UNIVERSIDAD DE COSTA RICA   (Costa Rica)

Author keywords

Adhesion molecules; Bothrops asper; Cytokines; Eicosanoids; Inflammation; Leukocytes; Snake venom PLA2

Indexed keywords

4 BROMOPHENACYL BROMIDE; ANTIBODY; ASPARTIC ACID; CD18 ANTIGEN; CELL ADHESION MOLECULE; ICOSANOID; L SELECTIN; LYSINE; PHOSPHOLIPASE A2; PHOSPHOLIPID; SNAKE VENOM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD VESSEL PERMEABILITY; CATALYSIS; CELL COUNT; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; HYDROLYSIS; INFLAMMATION; MOLECULAR INTERACTION; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PERITONEAL CAVITY; PERITONEUM; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

EID: 15944429322     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2004.11.004     Document Type: Article

References (55)

1. R.K. Arni, R.J. Ward, J.M. Gutiérrez, and A. Tulinsky Structure of a calcium-independent phospholipase-like myotoxic protein from Bothrops asper venom Acta. Cryst D51 1995 311 317
2. M.P. Bevilacqua, and R.M. Nelson Selectins J. Clin. Invest. 91 1993 379 387
3. 2 up-regulates cyclooxygenase-2 and amplifies cytokine-mediated prostaglandin production in human rheumatoid synoviocytes J. Immunol. 165 2000 2790 2797
4. F. Chaves, G. León, V.H. Alvarado, and J.M. Gutiérrez Pharmacological modulation of edema induced by Lys-49 and Asp-49 myotoxic phospholipases A2 isolated from the venom of the snake Bothrops asper (terciopelo) Toxicon 36 1998 1861 1869
5. 2 induced oedema in rat paw Eur. J. Pharmacol. 166 1989 505 510
6. 2 gene expression in human hepatoma cells by mediators of the acute phase response J. Biol. Chem. 266 1991 2647 2651
7. 2 into the rat pleural cavity Toxicon 38 2000 1773 1785
8. 2 in eicosanoid generation Am. J. Respir. Crit. Care. Med 161 2000 S32 S35
9. 2 variant, from Bothrops asper snake venom Nat. Toxins 3 1995 26 31
10. S.H.P. Farsky, L.R.C. Gonçalves, J.M. Gutiérrez, A.P. Correa, A. Rucavado, P. Gasque, and D.V. Tambourgi Bothrops asper snake venom and its metalloproteinase BaP-1 activate the complement system. Role in leucocyte recruitment Mediators Inflamm. 9 2000 213 221
11. A. Gambero, E.C. Landucci, M.H. Toyama, S. Marangoni, J.R. Giglio, H.B. Nader, C.P. Dietrich, G. de Nucci, and E. Antunes Human neutrophil migration in vitro induced by secretory phospholipases A2: a role for cell surface glycosaminoglycans Biochem. Pharmacol. 63 1 2002 65 72
12. 2 myotoxins from Bothrops snake venoms Toxicon 33 1995 1405 1424
13. J.M. Gutierrez, C.L. Ownby, and G.V. Odell Pathogenesis of myonecrosis induced by crude venom and a myotoxin of Bothrops asper Exp. Mol. Pathol. 40 1984 367 379
14. J.M. Gutierrez, B. Lomonte, F. Chaves, E. Moreno, and L. Cerdas Pharmacological activities of a toxic phospholipase A isolated from the venom of the snake Bothrops asper Comp. Biochem. Physiol. 84C 1986 59 64
15. J.M. Gutierrez, F. Chaves, J.A. Gene, B. Lomonte, Z. Camacho, and K. Schosinsky Myonecrosis induced by a basic myotoxin isolated from the venom of the snake Bothrops nummifer (jumping viper) from Costa Rica Toxicon 27 1989 735 746
16. 2 isolated from the venom of the snake Bothrops jararacussu Exp. Mol. Pathol. 55 1991 217 229
17. R.L. Hoover, M.J. Karnovsky, K.F. Austen, E.J. Corey, and R.A. Lewis Leukotriene B4 action on endothelium mediates augmented neutrophil/endothelial adhesion Proc. Natl Acad. Sci. USA 81 7 1984 2191 2193
18. A. Hubbard, and R. Rothlein Intercellular adhesion molecule-1 (ICAM-1) expression and cell signaling cascades Free Radic. Biol. Med. 28 2000 1379 1386
19. 2 receptor blockade suppresses intercellular adhesion molecule-1 expression by stimulated vascular endothelial cells Eur. J. Pharmacol. 312 1996 367 377
20. I.I. Kaiser, J.M. Gutiérrez, D. Plummer, S.D. Aird, and G.V. Odell The amino acid sequence of a myotoxic phospholipase from the venom of Bothrops asper Arch. Biochem. Biophys. 278 1990 319 325
21. G. Kaplanski, V. Marin, F. Montero-Julian, A. Mantovani, and C. Farnarier IL-6: a regulator of the transition from neutrophil to monocyte recruitment during inflamation Trends Immunol. 24 1 2003 25 29
22. 2 enzymes Structure, Function and Mechanisms 1997 Wiley New York
23. 2 enzymes J. Mol. Evol. 48 1999 125 132
24. 2 homologues: dissociation between enzymatic and biological activities Eur. J. Pharmacol. 343 1998 257 263
25. 2 homologue piratoxin-I in the rat and rabbit. Effect of polyanions and p-bromophenacyl bromide Biochem. Pharmacol. 59 2000 1289 1294
26. M.B. Lawrence, and T.A. Springer Leukocytes roll on a selectin at physiologic flow rates: distinction from and prerequisite for adhesion through integrins Cell 65 5 1991 859 873
27. 2 purified from porcine pancreas and snake venoms Toxicon 31 1993 949 956
28. B. Lomonte, and J.M. Gutierrez A new muscle damaging toxin, myotoxin II, from the venom of the snake Bothrops asper (terciopelo) Toxicon 27 1989 725 733
29. B. Lomonte, A. Tarkowski, and L.A. Hanson Host response to Bothrops asper snake venom. Analysis of edema formation, inflammatory cells, and cytokine release in a mouse model Inflammation 17 1993 93 105
30. 2 from Bothrops asper snake venom. Identification of a heparin-binding and cytolytic region by the use of synthetic peptides and molecular modeling J. Biol. Chem. 269 1994 29867 29873
31. C.E. Nunez, Y. Angulo, and B. Lomonte Identification of the myotoxic site of the Lys49 phospholipase A(2) from Agkistrodon piscivorus piscivorus snake venom: synthetic C-terminal peptides from Lys49, but not from Asp49 myotoxins, exert membrane-damaging activities Toxicon 39 2001 1587 1594
32. 2 proteins Toxicon 37 1999 411 445
33. J. Palmblad, P. Lindstrom, and R. Lerner Leukotriene B4 induced hyperadhesiveness of endothelial cells for neutrophils Biochem. Biophys. Res. Commun. 166 2 1990 848 851
34. V.L. Petricevich, C.F. Teixeira, D.V. Tambourgi, and J.M. Gutierrez Increments in serum cytokine and nitric oxide levels in mice injected with Bothrops asper and Bothrops jararaca snake venoms Toxicon 38 9 2000 1253 1266
35. P. Pradelles, J. Grassi, and J. Maclouf Enzyme immunoassays of eicosanoids using acetylcholine esterase as label: na alternative to radioimmunoassay Anal. Chem. 57 7 1985 1170 1173
36. 2 lacking enzymatic activity Biochemistry 42 2003 11494 11503
37. M.R. Ruff, and G.E. Gifford Rabbit tumor necrosis factor: mechanism of action Infect. Immun. 31 1 1981 380 385
38. G.B. Ryan, and G. Majno Acute inflammation Am. J. Pathol. 86 1977 185 274
39. 2 in rat mesangial cells Biochem. Biophys. Res. Commun. 174 1991 268 725
40. J.H. Schumaker, A. O'Garra, B. Schrader, A. Van Kimmeenade, M.W. Bond, T.R. Mosmann, and R.L. Coffman The characterization of four monoclonal antibodies specific for mouse IL-5 and development of mouse and human IL-5 ELISA J. Immunol. 141 1988 1576 1581
41. 4 on the adhesive kinets of LFA-1 and Mac-1 on human neutrophils Am. J. Phys. Cell. Phys. 281 2001 C1508 C1578
42. M.G. Sirois, S. Jancar, P. Braquet, G.E. Plante, and P. Sirois PAF increases vascular permeability in selected tissues: effect of BN-52021 and L-655, 240 Prostaglandins 36 5 1988 631 644
43. J.V. Snick Interleukin-6: an overview Annu. Rev. Immunol. 8 1990 253 278
44. 2 homologue from Bothrops moojeni (caissaca) snake venom Arch. Biochem. Biophys. 373 2000 7 15
45. 2 homologue from Bothrops neuwiedi paoloensis venom Arch. Biochem. Biophys. 378 2000 201 209
46. E. Stylianou, and J. Saklatvala Molecules in Focus Interleukin-1 Intern. J. Biochem. Cell. Biol. 30 1998 1075 1079
47. T. Suwa, J.C. Hogg, D. English, and S.F. Van Eeden Interleukin-6 induces demargination of intravascular neutrophils and shortens their transit in marrow Am. J. Physiol. Heart Circ. Physiol. 279 6 2000 H2954 H2960
48. T. Suwa, J.C. Hogg, K.B. Quinlan, and S.F. Van Eeden The effect of interleukin-6 on l-selectin levels on polymorphonuclear leukocytes Am. J. Physiol. Heart Circ. Physiol. 283 3 2002 H879 H884
49. R.D. Thompson, K.E. Noble, K.Y. Lardbi, A. Dewar, G.S. Duncan, T.W. Mak, and S. Nourshargh Platelet-endothelial cell adhesion molecule-1 (PECAM-1) in leukocyte migration through the perivascular basement membrane Blood 97 2001 1854 1860
50. 2 enzymes from Habu venom and their interaction with aristolochic acid Toxicon 25 1987 501 515
51. 2 enzymes Eur. J. Pharmacol. 190 1990 347 354
52. 2 PNAS USA 95 1998 15345 15350
53. M.E. Wiles, R. Welborn, G. Goldman, H.B. Hechtman, and D. Shepro Thromboxane-induced neutrophil adhesion to pulmonary microvascular and aortic endothelium is regulated by CD18 Inflammation 15 1991 181 197
54. 2 from Chinese cobra (Naja naja atra) venom Toxicon 37 1999 783 799
55. G.A. Zimmerman, S.M. Prescott, and T.M. McIntyre Endothelial cell interactions with granulocytes: tethering and signaling molecules Immunol. Today 13 1992 93 100