Crystal structure of a myotoxic Asp49-phospholipase A2 with low catalytic activity: Insights into Ca2+-independent catalytic mechanism

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1784, Issue 4, 2008, Pages 591-599

  Corrêa, Luiz C ^a   Marchi Salvador, Daniela P ^a   Cintra, Adélia C O ^b   Sampaio, Suely V ^b   Soares, Andreimar M ^b   Fontes, Marcos R M ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Bothrops jararacussu venom; Ca2+ independent enzymatic activity; Myotoxic; Phospholipase A2; X ray crystallography

Indexed keywords

ASPARTIC ACID; BATROXOBIN; BTHTX II ENZYME; PHOSPHOLIPASE A2; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; ENZYME ACTIVITY; ENZYME STRUCTURE; HYDROGEN BOND; NONHUMAN; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMALS; BOTHROPS; CALCIUM; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHOSPHOLIPASES A2; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; SNAKE VENOMS;

BOTHROPS JARARACUSSU;

EID: 40849111743     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbapap.2008.01.007     Document Type: Article

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