Crystallographic and spectroscopic characterization of a molecular hinge: Conformational changes in Bothropstoxin I, a dimeric Lys49- phospholipase A2 homologue

Proteins: Structure, Function and Genetics

Volumn 30, Issue 4, 1998, Pages 442-454

  Da Silva Giotto, M T ^a   Garratt, R C ^a   Oliva, G ^a   Mascarenhas, Y P ^a   Giglio, J R ^a   Cintra, A C O ^a   De Azevedo Jr , W F ^b   Arni, R K ^b   Ward, R J ^a,b  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

Protein membrane interaction; Quaternary structural change; Spectroscopy; Venom toxin; X ray diffraction

Indexed keywords

DIMER; LYSINE; MONOMER; PHOSPHOLIPASE A2; SNAKE VENOM; TRYPTOPHAN;

AMINO ACID SUBSTITUTION; ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; FLUORESCENCE SPECTROSCOPY; LIPID MEMBRANE; MEMBRANE DAMAGE; PRIORITY JOURNAL; PROTEIN QUATERNARY STRUCTURE; SEQUENCE HOMOLOGY; TOXIN STRUCTURE; X RAY CRYSTALLOGRAPHY; X RAY DIFFRACTION;

ANIMALS; BOTHROPS; CROTALID VENOMS; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; LYSINE; PHOSPHOLIPASES A; PROTEIN CONFORMATION; SPECTRUM ANALYSIS;

BOTHROPS JARARACUSSU; SERPENTES; VERTEBRATA;

EID: 0032031373     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0134(19980301)30:4<442::AID-PROT11>3.0.CO;2-I     Document Type: Article

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