A predominant role for hydrogen bonding in the stability of the homodimer of bothropstoxin-I, a lysine 49-phospholipase A2

Biochimie

Volumn 87, Issue 11, 2005, Pages 993-1003

  Ruller, R ^a   Aragao E A ^a   Chioato, L ^a   Ferreira, T Lopes ^a   De Oliveira, A H C ^a   Sa J M ^a   Ward, R J ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Dimer interface; Membrane damage; Mutagenesis; Myotoxin

Indexed keywords

BOTHROPSTOXIN 1; CALCIUM ION; DIMER; GLUTAMIC ACID; HYDROGEN; LIPOSOME; LYSINE; MARKER; MONOMER; PHOSPHOLIPASE A2; TOXIN; TRYPTOPHAN; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANIMAL TISSUE; ANISOTROPY; ARTICLE; CIRCULAR DICHROISM; CONTROLLED STUDY; CORRELATION ANALYSIS; DENATURATION; ENERGY; FLUORESCENCE; HYDROGEN BOND; HYDROPHOBICITY; MALE; MEMBRANE DAMAGE; MODEL; MOUSE; MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; SITE DIRECTED MUTAGENESIS; TOXICITY;

AMINO ACID SEQUENCE; ANIMALS; CIRCULAR DICHROISM; CROTALID VENOMS; DIMERIZATION; ENZYME STABILITY; FLUORESCENCE POLARIZATION; HYDROGEN BONDING; LIPOSOMES; MALE; MICE; MUTAGENESIS, SITE-DIRECTED; PHOSPHOLIPASES A; PROTEIN DENATURATION; PROTEIN STRUCTURE, QUATERNARY;

BOTHROPS JARARACUSSU;

EID: 25444519212     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2005.04.008     Document Type: Article

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