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Volumn 4, Issue 2, 2007, Pages 53-60

Human embryonic stem cells: A potential system for modeling infant leukemia harboring MLL-AF4 fusion gene

Author keywords

[No Author keywords available]

Indexed keywords

MIXED LINEAGE LEUKEMIA PROTEIN; ONCOPROTEIN; PROTEIN AF4; UNCLASSIFIED DRUG;

EID: 40849106320     PISSN: 17406757     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ddmod.2007.10.004     Document Type: Review
Times cited : (17)

References (47)
  • 1
    • 33646448921 scopus 로고    scopus 로고
    • Biology of normal and acute myeloid leukemia stem cells
    • Dick J.E., and Lapidot T. Biology of normal and acute myeloid leukemia stem cells. Int. J. Hematol. 82 (2005) 389-396
    • (2005) Int. J. Hematol. , vol.82 , pp. 389-396
    • Dick, J.E.1    Lapidot, T.2
  • 2
    • 24344506258 scopus 로고    scopus 로고
    • Cancer stem cells: lessons from leukemia
    • Wang J.C., and Dick J.E. Cancer stem cells: lessons from leukemia. Trends Cell Biol. 15 (2005) 494-501
    • (2005) Trends Cell Biol. , vol.15 , pp. 494-501
    • Wang, J.C.1    Dick, J.E.2
  • 3
    • 0027276927 scopus 로고
    • In utero rearrangements in the trithorax-related oncogene in infant leukaemias
    • Ford A.M., et al. In utero rearrangements in the trithorax-related oncogene in infant leukaemias. Nature 363 (1993) 358-360
    • (1993) Nature , vol.363 , pp. 358-360
    • Ford, A.M.1
  • 4
    • 0031471132 scopus 로고    scopus 로고
    • Backtracking leukemia to birth: identification of clonotypic gene fusion sequences in neonatal blood spots
    • Gale K.B., et al. Backtracking leukemia to birth: identification of clonotypic gene fusion sequences in neonatal blood spots. Proc. Natl. Acad. Sci. U S A 94 (1997) 13950-13954
    • (1997) Proc. Natl. Acad. Sci. U S A , vol.94 , pp. 13950-13954
    • Gale, K.B.1
  • 5
    • 0141482011 scopus 로고    scopus 로고
    • Leukemia in twins: lessons in natural history
    • Greaves M.F., et al. Leukemia in twins: lessons in natural history. Blood 102 (2003) 2321-2333
    • (2003) Blood , vol.102 , pp. 2321-2333
    • Greaves, M.F.1
  • 6
    • 0141634051 scopus 로고    scopus 로고
    • Origins of chromosome translocations in childhood leukaemia
    • Greaves M.F., and Wiemels J. Origins of chromosome translocations in childhood leukaemia. Nat. Rev. Cancer 3 (2003) 639-649
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 639-649
    • Greaves, M.F.1    Wiemels, J.2
  • 7
    • 13944274492 scopus 로고    scopus 로고
    • Leukemic stem cells in childhood high-risk ALL/t(9;22) and t(4;11) are present in primitive lymphoid-restricted CD34+
    • Hotfilder M., et al. Leukemic stem cells in childhood high-risk ALL/t(9;22) and t(4;11) are present in primitive lymphoid-restricted CD34+. Cancer Res. 65 (2005) 1442-1449
    • (2005) Cancer Res. , vol.65 , pp. 1442-1449
    • Hotfilder, M.1
  • 8
    • 0032491416 scopus 로고    scopus 로고
    • Embryonic stem cell lines derived from human blastocysts
    • Thomson J.A., et al. Embryonic stem cell lines derived from human blastocysts. Science 282 (1998) 1145-1147
    • (1998) Science , vol.282 , pp. 1145-1147
    • Thomson, J.A.1
  • 9
    • 33645505915 scopus 로고    scopus 로고
    • Scientific and clinical opportunities for modeling blood disorders with embryonic stem cells
    • Lensch M.W., and Daley G.Q. Scientific and clinical opportunities for modeling blood disorders with embryonic stem cells. Blood 107 (2006) 2605-2612
    • (2006) Blood , vol.107 , pp. 2605-2612
    • Lensch, M.W.1    Daley, G.Q.2
  • 10
    • 0345763041 scopus 로고    scopus 로고
    • Pre-natal origins of childhood leukemia
    • Greaves M. Pre-natal origins of childhood leukemia. Rev. Clin. Exp. Hematol. 7 (2003) 233-245
    • (2003) Rev. Clin. Exp. Hematol. , vol.7 , pp. 233-245
    • Greaves, M.1
  • 11
    • 0032717039 scopus 로고    scopus 로고
    • The role of chromosome translocations in leukemogenesis
    • Rowley J.D. The role of chromosome translocations in leukemogenesis. Semin. Hematol. 36 (1999) 59-72
    • (1999) Semin. Hematol. , vol.36 , pp. 59-72
    • Rowley, J.D.1
  • 12
    • 0034970067 scopus 로고    scopus 로고
    • An atlas of chromosomes in hematological malignancies. Example: 11q23 and MLL partners
    • Huret J.L., et al. An atlas of chromosomes in hematological malignancies. Example: 11q23 and MLL partners. Leukemia 15 (2001) 987-989
    • (2001) Leukemia , vol.15 , pp. 987-989
    • Huret, J.L.1
  • 13
    • 0034235115 scopus 로고    scopus 로고
    • Biological and therapeutic aspects of infant leukemia
    • Biondi A., et al. Biological and therapeutic aspects of infant leukemia. Blood 96 (2000) 24-33
    • (2000) Blood , vol.96 , pp. 24-33
    • Biondi, A.1
  • 14
    • 0032189081 scopus 로고    scopus 로고
    • Secondary leukemias induced by topoisomerase-targeted drugs
    • Felix C.A. Secondary leukemias induced by topoisomerase-targeted drugs. Biochim. Biophys. Acta 1400 (1998) 233-255
    • (1998) Biochim. Biophys. Acta , vol.1400 , pp. 233-255
    • Felix, C.A.1
  • 15
    • 20144389914 scopus 로고    scopus 로고
    • Maternal diet and infant leukemia: the DNA topoisomerase II inhibitor hypothesis: a report from the children's oncology group
    • Spector L.G., et al. Maternal diet and infant leukemia: the DNA topoisomerase II inhibitor hypothesis: a report from the children's oncology group. Cancer Epidemiol. Biomarkers Prev. 14 (2005) 651-655
    • (2005) Cancer Epidemiol. Biomarkers Prev. , vol.14 , pp. 651-655
    • Spector, L.G.1
  • 16
    • 0036197483 scopus 로고    scopus 로고
    • International workshop on the relationship of prior therapy to balanced chromosome aberrations in therapy-related myelodysplastic syndromes and acute leukemia: overview report
    • Rowley J.D., and Olney H.J. International workshop on the relationship of prior therapy to balanced chromosome aberrations in therapy-related myelodysplastic syndromes and acute leukemia: overview report. Genes Chromosomes Cancer 33 (2002) 331-345
    • (2002) Genes Chromosomes Cancer , vol.33 , pp. 331-345
    • Rowley, J.D.1    Olney, H.J.2
  • 17
    • 0029930974 scopus 로고    scopus 로고
    • Infant leukaemia biology, aetiology and treatment
    • Greaves M.F. Infant leukaemia biology, aetiology and treatment. Leukemia 10 (1996) 372-377
    • (1996) Leukemia , vol.10 , pp. 372-377
    • Greaves, M.F.1
  • 18
    • 1542283683 scopus 로고    scopus 로고
    • Protracted postnatal natural histories in childhood leukemia
    • Maia A.T., et al. Protracted postnatal natural histories in childhood leukemia. Genes Chromosomes Cancer 39 (2004) 335-340
    • (2004) Genes Chromosomes Cancer , vol.39 , pp. 335-340
    • Maia, A.T.1
  • 19
    • 9144244169 scopus 로고    scopus 로고
    • FLT3 mutations in the activation loop of tyrosine kinase domain are frequently found in infant ALL with MLL rearrangements and pediatric ALL with hyperdiploidy
    • Taketani T., et al. FLT3 mutations in the activation loop of tyrosine kinase domain are frequently found in infant ALL with MLL rearrangements and pediatric ALL with hyperdiploidy. Blood 103 (2004) 1085-1088
    • (2004) Blood , vol.103 , pp. 1085-1088
    • Taketani, T.1
  • 20
    • 0031898443 scopus 로고    scopus 로고
    • The translocations, t(11;19)(q23;p13.1) and t(11;19)(q23;p13.3): a cytogenetic and clinical profile of 53 patients. European 11q23 Workshop participants
    • Moorman A.V., et al. The translocations, t(11;19)(q23;p13.1) and t(11;19)(q23;p13.3): a cytogenetic and clinical profile of 53 patients. European 11q23 Workshop participants. Leukemia 12 (1998) 805-810
    • (1998) Leukemia , vol.12 , pp. 805-810
    • Moorman, A.V.1
  • 21
    • 17044413548 scopus 로고    scopus 로고
    • The versatile mixed lineage leukaemia gene MLL and its many associations in leukaemogenesis
    • Daser A., and Rabbitts T.H. The versatile mixed lineage leukaemia gene MLL and its many associations in leukaemogenesis. Semin Cancer Biol. 15 (2005) 175-188
    • (2005) Semin Cancer Biol. , vol.15 , pp. 175-188
    • Daser, A.1    Rabbitts, T.H.2
  • 22
    • 33745941911 scopus 로고    scopus 로고
    • A murine Mll-AF4 knock-in model results in lymphoid and myeloid deregulation and hematologic malignancy
    • Chen W., et al. A murine Mll-AF4 knock-in model results in lymphoid and myeloid deregulation and hematologic malignancy. Blood 108 (2006) 669-677
    • (2006) Blood , vol.108 , pp. 669-677
    • Chen, W.1
  • 23
    • 33745103352 scopus 로고    scopus 로고
    • A conditional model of MLL-AF4 B-cell tumourigenesis using invertor technology
    • Metzler M., et al. A conditional model of MLL-AF4 B-cell tumourigenesis using invertor technology. Oncogene 25 (2006) 3093-3103
    • (2006) Oncogene , vol.25 , pp. 3093-3103
    • Metzler, M.1
  • 24
    • 34249104594 scopus 로고    scopus 로고
    • Combined effects of the two reciprocal t(4;11) fusion proteins MLL.AF4 and AF4.MLL confer resistance to apoptosis, cell cycling capacity and growth transformation
    • Gaussmann A., et al. Combined effects of the two reciprocal t(4;11) fusion proteins MLL.AF4 and AF4.MLL confer resistance to apoptosis, cell cycling capacity and growth transformation. Oncogene 26 (2007) 3352-3363
    • (2007) Oncogene , vol.26 , pp. 3352-3363
    • Gaussmann, A.1
  • 25
    • 33745728281 scopus 로고    scopus 로고
    • MLL chimeric protein activation renders cells vulnerable to chromosomal damage: an explanation for the very short latency of infant leukemia
    • Eguchi M., et al. MLL chimeric protein activation renders cells vulnerable to chromosomal damage: an explanation for the very short latency of infant leukemia. Genes Chromosomes Cancer 45 (2006) 754-760
    • (2006) Genes Chromosomes Cancer , vol.45 , pp. 754-760
    • Eguchi, M.1
  • 26
    • 33747892853 scopus 로고    scopus 로고
    • Topoisomerase II and the etiology of chromosomal translocations
    • Felix C.A., et al. Topoisomerase II and the etiology of chromosomal translocations. DNA Repair (Amst) 5 (2006) 1093-1108
    • (2006) DNA Repair (Amst) , vol.5 , pp. 1093-1108
    • Felix, C.A.1
  • 27
    • 18844396119 scopus 로고    scopus 로고
    • Embryonic stem cell differentiation: emergence of a new era in biology and medicine
    • Keller G. Embryonic stem cell differentiation: emergence of a new era in biology and medicine. Genes Dev. 19 (2005) 1129-1155
    • (2005) Genes Dev. , vol.19 , pp. 1129-1155
    • Keller, G.1
  • 28
    • 33845315254 scopus 로고    scopus 로고
    • Human embryonic stem cells: A journey beyond cell replacement therapies
    • Menendez P., et al. Human embryonic stem cells: A journey beyond cell replacement therapies. Cytotherapy 8 (2006) 530-541
    • (2006) Cytotherapy , vol.8 , pp. 530-541
    • Menendez, P.1
  • 29
    • 21744441322 scopus 로고    scopus 로고
    • Human embryonic stem cells as a model for nutritional programming: an evaluation
    • Allegrucci C., et al. Human embryonic stem cells as a model for nutritional programming: an evaluation. Reprod. Toxicol. 20 (2005) 353-367
    • (2005) Reprod. Toxicol. , vol.20 , pp. 353-367
    • Allegrucci, C.1
  • 30
    • 13444301598 scopus 로고    scopus 로고
    • Embryonic and fetal programming of physiological disorders in adulthood
    • Lau C., and Rogers J.M. Embryonic and fetal programming of physiological disorders in adulthood. Birth Defects Res. C. Embryo Today 72 (2004) 300-312
    • (2004) Birth Defects Res. C. Embryo Today , vol.72 , pp. 300-312
    • Lau, C.1    Rogers, J.M.2
  • 31
    • 15544369982 scopus 로고    scopus 로고
    • Developmental origins of the metabolic syndrome: prediction, plasticity, and programming
    • McMillen I.C., and Robinson J.S. Developmental origins of the metabolic syndrome: prediction, plasticity, and programming. Physiol. Rev. 85 (2005) 571-633
    • (2005) Physiol. Rev. , vol.85 , pp. 571-633
    • McMillen, I.C.1    Robinson, J.S.2
  • 32
    • 13544255602 scopus 로고    scopus 로고
    • The fetal, neonatal, and infant environments-the long-term consequences for disease risk
    • Gluckman P.D., et al. The fetal, neonatal, and infant environments-the long-term consequences for disease risk. Early Hum. Dev. 81 (2005) 51-59
    • (2005) Early Hum. Dev. , vol.81 , pp. 51-59
    • Gluckman, P.D.1
  • 33
    • 17044428415 scopus 로고    scopus 로고
    • Understanding mesenchymal cancer: the liposarcoma-associated FUS-DDIT3 fusion gene as a model
    • Perez-Mancera P.A., and Sanchez-Garcia I. Understanding mesenchymal cancer: the liposarcoma-associated FUS-DDIT3 fusion gene as a model. Semin. Cancer Biol. 15 (2005) 206-214
    • (2005) Semin. Cancer Biol. , vol.15 , pp. 206-214
    • Perez-Mancera, P.A.1    Sanchez-Garcia, I.2
  • 34
    • 28044468016 scopus 로고    scopus 로고
    • EWS-ETS oncoproteins: the linchpins of Ewing tumors
    • Janknecht R. EWS-ETS oncoproteins: the linchpins of Ewing tumors. Gene 363 (2005) 1-14
    • (2005) Gene , vol.363 , pp. 1-14
    • Janknecht, R.1
  • 35
    • 0035892108 scopus 로고    scopus 로고
    • Peripheral blood stem cell versus bone marrow allotransplantation: does the source of hematopoietic stem cells matter?
    • Korbling M., and Anderlini P. Peripheral blood stem cell versus bone marrow allotransplantation: does the source of hematopoietic stem cells matter?. Blood 98 (2001) 2900-2908
    • (2001) Blood , vol.98 , pp. 2900-2908
    • Korbling, M.1    Anderlini, P.2
  • 36
    • 0037871588 scopus 로고    scopus 로고
    • Cytokines and BMP-4 promote hematopoietic differentiation of human embryonic stem cells
    • Chadwick K., et al. Cytokines and BMP-4 promote hematopoietic differentiation of human embryonic stem cells. Blood 102 (2003) 906-915
    • (2003) Blood , vol.102 , pp. 906-915
    • Chadwick, K.1
  • 37
    • 1642306055 scopus 로고    scopus 로고
    • VEGF-A165 augments erythropoietic development from human embryonic stem cells
    • Cerdan C., et al. VEGF-A165 augments erythropoietic development from human embryonic stem cells. Blood 103 (2004) 2504-2512
    • (2004) Blood , vol.103 , pp. 2504-2512
    • Cerdan, C.1
  • 38
    • 0030831104 scopus 로고    scopus 로고
    • A requirement for Flk1 in primitive and definitive hematopoiesis and vasculogenesis
    • Shalaby F., et al. A requirement for Flk1 in primitive and definitive hematopoiesis and vasculogenesis. Cell 89 (1997) 981-990
    • (1997) Cell , vol.89 , pp. 981-990
    • Shalaby, F.1
  • 39
    • 0030770898 scopus 로고    scopus 로고
    • CD34 expression patterns during early mouse development are related to modes of blood vessel formation and reveal additional sites of hematopoiesis
    • Wood H.B., et al. CD34 expression patterns during early mouse development are related to modes of blood vessel formation and reveal additional sites of hematopoiesis. Blood 90 (1997) 2300-2311
    • (1997) Blood , vol.90 , pp. 2300-2311
    • Wood, H.B.1
  • 40
    • 3142776112 scopus 로고    scopus 로고
    • Endothelial and hematopoietic cell fate of human embryonic stem cells originates from primitive endothelium with hemangioblastic properties
    • Wang L., et al. Endothelial and hematopoietic cell fate of human embryonic stem cells originates from primitive endothelium with hemangioblastic properties. Immunity 21 (2004) 31-41
    • (2004) Immunity , vol.21 , pp. 31-41
    • Wang, L.1
  • 41
    • 24044465198 scopus 로고    scopus 로고
    • Hematopoietic development from human embryonic stem cell lines
    • Wang L., et al. Hematopoietic development from human embryonic stem cell lines. Exp. Hematol. 33 (2005) 987-996
    • (2005) Exp. Hematol. , vol.33 , pp. 987-996
    • Wang, L.1
  • 42
    • 10344240351 scopus 로고    scopus 로고
    • Retroviral transduction of hematopoietic cells differentiated from human embryonic stem cell-derived CD45(neg)PFV hemogenic precursors
    • Menendez P., et al. Retroviral transduction of hematopoietic cells differentiated from human embryonic stem cell-derived CD45(neg)PFV hemogenic precursors. Mol. Ther. 10 (2004) 1109-1120
    • (2004) Mol. Ther. , vol.10 , pp. 1109-1120
    • Menendez, P.1
  • 43
    • 33748992563 scopus 로고    scopus 로고
    • Clonal isolation of hESCs reveals heterogeneity within the pluripotent stem cell compartment
    • Stewart M.H., et al. Clonal isolation of hESCs reveals heterogeneity within the pluripotent stem cell compartment. Nat. Methods 3 (2006) 807-815
    • (2006) Nat. Methods , vol.3 , pp. 807-815
    • Stewart, M.H.1
  • 44
    • 33344461144 scopus 로고    scopus 로고
    • Human embryonic stem cell-derived hematopoietic cells are capable of engrafting primary as well as secondary fetal sheep recipients
    • Narayan A.D., et al. Human embryonic stem cell-derived hematopoietic cells are capable of engrafting primary as well as secondary fetal sheep recipients. Blood 107 (2006) 2180-2183
    • (2006) Blood , vol.107 , pp. 2180-2183
    • Narayan, A.D.1
  • 45
    • 33746897865 scopus 로고    scopus 로고
    • Hematopoietic engraftment of human embryonic stem cell-derived cells is regulated by recipient innate immunity
    • Tian X., et al. Hematopoietic engraftment of human embryonic stem cell-derived cells is regulated by recipient innate immunity. Stem Cells 24 (2006) 1370-1380
    • (2006) Stem Cells , vol.24 , pp. 1370-1380
    • Tian, X.1
  • 46
    • 2942691389 scopus 로고    scopus 로고
    • Stem cell origin of cancer and differentiation therapy
    • Sell S. Stem cell origin of cancer and differentiation therapy. Crit. Rev. Oncol. Hematol. 51 (2004) 1-28
    • (2004) Crit. Rev. Oncol. Hematol. , vol.51 , pp. 1-28
    • Sell, S.1
  • 47
    • 33845300700 scopus 로고    scopus 로고
    • APL and differentiation therapy-joint international congress
    • Zelent A. APL and differentiation therapy-joint international congress. IDrugs 4 (2001) 1257-1262
    • (2001) IDrugs , vol.4 , pp. 1257-1262
    • Zelent, A.1


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