The translocations, t(11;19)(q23;p13.1) and t(11;19)(q23;p13.3): A cytogenetic and clinical profile of 53 patients

Leukemia

Volumn 12, Issue 5, 1998, Pages 805-810

  Moorman, A V ^a,e   Hagemeijer, A ^b   Charrin, C ^c   Rieder, H ^d   Seeker Walker, L M ^a  

^a ROYAL FREE HOSPITAL   (United Kingdom)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c EDOUARD HERRIOT HOSPITAL   (France)

^d PHILIPPS UNIVERSITY MARBURG   (Germany)

^e LRF Centre for Clinical Epidemiology   (United Kingdom)

Author keywords

11q23; Acute lymphoblastic leukemia; Acute myeloid leukemia; Myelodysplastic syndrome; t(11; 19)

Indexed keywords

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LEUKEMIA; ACUTE LYMPHOBLASTIC LEUKEMIA; CANCER SURVIVAL; CHROMOSOME 11Q; CHROMOSOME 19; CHROMOSOME BREAKAGE; CONFERENCE PAPER; GENE TRANSLOCATION; HUMAN; INFANT; KARYOTYPE; MAJOR CLINICAL STUDY; MYELODYSPLASTIC SYNDROME; PRESCHOOL CHILD; PRIORITY JOURNAL;

EID: 0031898443     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2401016     Document Type: Conference Paper

References (23)

1. Mitelman F. Catalog of Chromosome Aberrations in Cancer. 6th edn. Wiley-Liss: New York, 1998 (in press).
2. Morgan GJ, Cotter F, Katz FE, Ridge SA, Domer P, Korsmeyer S. Breakpoints at 11q23 in infant leukemias with the t(11;19)(q23; p13) are clustered. Blood 1992; 80: 2172-2175.
3. Huret JL, Brizard A, Slater R, Charrin C, Bertheas MF, Guilhot F, Kroes W, van Leeuwen E, School EV et al. Cytogenetic heterogeneity in t(11;19) acute leukemia: clinical, hematological and cytogenetic analyses of 48 patients - updated published cases and 16 new observations (review). Leukemia 1993; 7: 152-160.
4. Mitani K, Sato Y, Kobayashi Y, Shibasaki Y, Kasuga M, Inaba T, Hayashi Y, Miura Y, Miyazono K, Hirai H et al. Heterogeneity in the breakpoints of chromosome 19 among acute leukemic patients with the t(11 ;19)(q23;p13) translocation. Am J Hematol 1989; 31: 253-257.
5. Hudson MM, Raimondi SC, Behm FG, Pui CH. Childhood acute leukemia with t(11;19) (q23;p13). Leukemia 1991; 5: 1064-1068.
6. Djabali M, Selleri L, Parry P, Bower M, Young BD, Evans GA. A trithorax-like gene is interrupted by chromosome 11q23 translocations in acute leukaemias. Nat Genet 1992; 2: 113-118.
7. Ziemin Van der Poel S, McCabe NR, Gill HJ, Espinosa R III, Patel Y, Harden A, Rubinelli P, Smith SD, Le Beau MM, Rowley JD, Diaz MO. Identification of a gene, MIL, that spans the breakpoint in 11q23 translocations associated with human leukemias. Proc Natl Acad Sci USA 1991; 88: 10735-10739.
8. Cimino G, Moir DJ, Canaani O, Williams K, Crist W, Katzav S, Cannizzaro LA, Lange B, Nowell P, Croce C. Cloning of ALL-1, the locus involved in leukemias with the t(4;11)(q21;q23), t(9;11)(p22;q23), and t(11;19)(q23;p13) chromosome translocations. Cancer Res 1991; 51: 6712-6714.
9. Mitani K, Kanda Y, Ogawa S, Tanaka T, Inazawa J, Yazaki Y, Hirai H. Cloning of several species of MLL/MEN chimeric cDNAs in myeloid leukemia with t(11;19)(q23;p13.1) translocation. Blood 1995; 85: 2017-2024.
10. Thirman MJ, Levitan DA, Kobayashi H, Simon MC, Rowley JD. Cloning of ELL, a gene that fuses to MLL in a t(11;19)(q23;p13.1) in acute myeloid leukemia. Proc Natl Acad Sci USA 1994; 91: 12110-12114.
11. Tkachuk DC, Kohler S, Cleary ML. Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias. Cell 1992; 71: 691-700.
12. Yamamoto K, Seto M, Komatsu H, Iida S, Akao Y, Kojima S, Kodera Y, Nakazawa S, Ariyoshi Y, Takahashi T. Two distinct portions of LTG19/ENL at 19p13 are involved in t(11;19) leukemia. Oncogene 1993; 8: 2617-2625 (Abstr.).
13. Iida S, Seto M, Yamamoto K, Komatsu H, Akao Y, Nakazawa S, Ariyoshi Y, Takahashi T, Ueda R. Molecular cloning of 19p13 breakpoint region in infantile leukemia with t(11;19)(q23;p13) translocation. Jpn J Cancer Res 1993; 84: 532-537.
14. So CW, Caldas C, Liu MM, Chen SJ, Huang QH, Gu LJ, Sham MH, Wiedemann LM, Chan LC. EEN encodes for a member of a new family of proteins containing an Src homology 3 domain and is the third gene located on chromosome 19p13 that fuses to MLL in human leukemia. Proc Natl Acad Sci USA 1997; 94: 2563-2568.
15. Rubnitz JE, Behm FG, Curcio-Brint AM, Pinheiro VRP, Carroll AJ, Raimondi SC, Shurtleff SA, Downing JR. Molecular analysis of t(11;19) breakpoints in childhood acute leukemias. Blood 1996; 87: 4804-4808.
16. Seeker-Walker LM, on behalf of the European 11q23 Workshop Participants. General Report on the European Union Concerted Action Workshop on 11q23. Leukemia 1998; 12: 776-778.
17. Gibbons B, Katz FE, Ganly P, Chessells JM. Infant acute lymphoblastic leukaemia with t(11;19). Br J Haematol 1990; 74: 264-269.
18. Archimbaud E, Charrin C, Magaud JP, Campos L, Thomas X, Fiere D, Rimokh R. Clinical and biological characteristics of adult de novo and secondary adult myeloid leukemia with balanced 11 q23 chromosomal anomaly or MLL gene rearrangement compared to cases with unbalanced 11q23 anomaly: confirmation of the existence of different entities with 11q23 breakpoint. Leukemia 1998; 12: 25-33.
19. Carbonell F, Swansbury J, Min T, Farahat N, Buccheri V, Morilla R, Seeker-Walker LM, Catovsky D. Cytogenetic findings in acute biphenotypic leukemia. Leukemia 1996; 10: 1283-1287.
20. Horstmann M, Argyriou-Tirita A, Borkhardt A, Kabisch H, Kapaun P, Winkler K, Haas OA. MLL/ENL fusion in congenital acute lymphoblastic leukemia with a unique t(11;18;19). Cancer Genet Cytogenet 1996; 88: 103-109.
21. European Croup for the Immunological Characterization of Leukemias (EGIL), Bene MC, Castoldi G, Knapp W, Ludwig WD, Matutes E, Orfao A, Van't Veer MB. Proposal for the immunological classification of acute leukemias. Leukemia 1995; 9: 1783-1786.
22. Johansson B, Moorman AV, Seeker-Walker LM, on behalf of the European 11q23 Workshop Participants. Derivative chromosomes of 11q23-translocations in hematologic malignancies. Leukemia 1998; 12: 828-833.
23. Felix CA, Hosler MR, Winick NJ, Masterson M, Wilson A, Lange BJ. ALL-1 gene rearrangements in DNA topoisomerase II inhibitorrelated leukemia in children. Blood 1995; 85: 3250-3256.